A global optimisation approach to classification in medical diagnosis and prognosis
- Authors: Bagirov, Adil , Rubinov, Alex , Yearwood, John , Stranieri, Andrew
- Date: 2001
- Type: Text , Conference paper
- Relation: Paper presented at 34th Hawaii International Conference on System Sciences, HICSS-34, Maui, Hawaii, USA : 3rd-6th January 2001
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- Description: In this paper global optimisation-based techniques are studied in order to increase the accuracy of medical diagnosis and prognosis with FNA image data from the Wisconsin Diagnostic and Prognostic Breast Cancer databases. First we discuss the problem of determining the most informative features for the classification of cancerous cases in the databases under consideration. Then we apply a technique based on convex and global optimisation to breast cancer diagnosis. It allows the classification of benign cases and malignant ones and the subsequent diagnosis of patients with very high accuracy. The third application of this technique is a method that calculates centres of clusters to predict when breast cancer is likely to recur in patients for which cancer has been removed. The technique achieves higher accuracy with these databases than reported elsewhere in the literature.
- Description: 2003003950
A simulated annealing-based maximum-margin clustering algorithm
- Authors: Seifollahi, Sattar , Bagirov, Adil , Borzeshi, Ehsan , Piccardi, Massimo
- Date: 2019
- Type: Text , Journal article
- Relation: Computational Intelligence Vol. 35, no. 1 (2019), p. 23-41
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- Reviewed:
- Description: Maximum-margin clustering is an extension of the support vector machine (SVM) to clustering. It partitions a set of unlabeled data into multiple groups by finding hyperplanes with the largest margins. Although existing algorithms have shown promising results, there is no guarantee of convergence of these algorithms to global solutions due to the nonconvexity of the optimization problem. In this paper, we propose a simulated annealing-based algorithm that is able to mitigate the issue of local minima in the maximum-margin clustering problem. The novelty of our algorithm is twofold, ie, (i) it comprises a comprehensive cluster modification scheme based on simulated annealing, and (ii) it introduces a new approach based on the combination of k-means++ and SVM at each step of the annealing process. More precisely, k-means++ is initially applied to extract subsets of the data points. Then, an unsupervised SVM is applied to improve the clustering results. Experimental results on various benchmark data sets (of up to over a million points) give evidence that the proposed algorithm is more effective at solving the clustering problem than a number of popular clustering algorithms.
Data mining with combined use of optimization techniques and self-organizing maps for improving risk grouping rules : Application to prostate cancer patients
- Authors: Churilov, Leonid , Bagirov, Adil , Schwartz, Daniel , Smith, Kate , Dally, Michael
- Date: 2005
- Type: Text , Journal article
- Relation: Journal of Management Information Systems Vol. 21, no. 4 (2005), p. 85-100
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- Description: Data mining techniques provide a popular and powerful tool set to generate various data-driven classification systems. In this paper, we investigate the combined use of self-organizing maps (SOM) and nonsmooth nonconvex optimization techniques in order to produce a working case of a data-driven risk classification system. The optimization approach strengthens the validity of SOM results, and the improved classification system increases both the quality of prediction and the homogeneity within the risk groups. Accurate classification of prostate cancer patients into risk groups is important to assist in the identification of appropriate treatment paths. We start with the existing rules and aim to improve classification accuracy by identifying inconsistencies utilizing self-organizing maps as a data visualization tool. Then, we progress to the study of assigning prostate cancer patients into homogenous groups with the aim to support future clinical treatment decisions. Using the case of prostate cancer patients grouping, we demonstrate strong potential of data-driven risk classification schemes for addressing the risk grouping issues in more general organizational settings. © 2005 M.E. Sharpe, Inc.
- Description: C1
- Description: 2003001265