Showing items 1 - 20 of 13227

1-Methyl-1 H-pyrazole-5-carboxamide derivatives exhibit unexpected acute mammalian toxicity

- Preston, Sarah, Garcia-Bustos, Jose, Hall, Liam, Martin, Sheree, Le, Thuy

  • Authors: Preston, Sarah , Garcia-Bustos, Jose , Hall, Liam , Martin, Sheree , Le, Thuy
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Journal of Medicinal Chemistry Vol. 64, no. 1 (2021), p. 840-844
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  • Description: A series of 1-methyl-1H-pyrazole-5-carboxamides were synthesized as potent inhibitors of the parasitic nematode of sheep, Haemonchus contortus. These compounds did not show overt cytotoxicity to a range of mammalian cell lines under standard in vitro culture conditions, had high selectivity indices, and were progressed to an acute toxicity study in a rodent model. Strikingly, acute toxicity was observed in mice. Experiments measuring cellular respiration showed a dose-dependent inhibition of mitochondrial respiration. Under these conditions, potent cytotoxicity was observed for these compounds in rat hepatocytes suggesting that the potent acute mammalian toxicity of this chemotype is most likely associated with respiratory inhibition. In contrast, parasite toxicity was not correlated to acute toxicity or cytotoxicity in respiring cells. This paper highlights the importance of identifying an appropriate in vitro predictor of in vivo toxicity early on in the drug discovery pipeline, in particular assessment for in vitro mitochondrial toxicity. © 2020 American Chemical Society. *Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Sarah Preston” is provided in this record**

A field investigation of the relationship between rotating shifts, sleep, mental health and physical activity of Australian paramedics

- Khan, Wahaj, Jackson, Melinda, Kennedy, Gerard, Conduit, Russell

  • Authors: Khan, Wahaj , Jackson, Melinda , Kennedy, Gerard , Conduit, Russell
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Scientific Reports Vol. 11, no. 1 (2021), p.
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  • Description: Paramedics working on a rotating shift are at an increased risk of developing chronic health issues due to continuous circadian rhythm disruption. The acute effects of shift rotation and objectively measured sleep have rarely been reported in paramedics. This study investigated the relationships between a rotating shift schedule and sleep (using actigraphy), subjective reports of sleepiness, mood, stress and fatigue. Galvanic Skin Response, energy expenditure and physical activity (BodyMedia SenseWear Armband) were also recorded across the shift schedule. Paramedics were monitored for a period of eight consecutive days across pre-shift, day shift, night shift, and 2 days off. Fifteen paramedics (M age = 39.5 and SD = 10.7 years) who worked rotational shifts experienced sleep restriction during night shift compared to pre-shift, day shift and days off (p < 0.001). Night shift was also associated with higher levels of stress (p < 0.05), fatigue (p < 0.05), and sleepiness (p < 0.05). One day off was related to a return to pre-shift functioning. Such shift-related issues have a compounding negative impact on an already stressful occupation with high rates of physical and mental health issues. Therefore, there is an urgent need to investigate methods to reduce rotating shift burden on the health of paramedics. This could be through further research aimed at providing recommendations for shift work schedules with sufficient periods for sleep and recovery from stress. © 2021, The Author(s).

A new global index for short term voltage stability assessment

- Alshareef, Abdulrhman, Shah, Rakibuzzaman, Mithulananthan, Nadarajah, Alzahrani, Saeed

  • Authors: Alshareef, Abdulrhman , Shah, Rakibuzzaman , Mithulananthan, Nadarajah , Alzahrani, Saeed
  • Date: 2021
  • Type: Text , Journal article
  • Relation: IEEE Access Vol. 9, no. (2021), p. 36114-36124
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  • Description: The utility scale of non-conventional generators (NCGs), such as wind and photovoltaic (PV) plants, are competitive alternatives to synchronous machines (SMs) for power generation. Higher penetration of NCGs has been respondent of causing several recent incidents leading up to voltage collapse in power systems due to the distinct characteristics of NCGs under different operating conditions. Consequently, the so-called system strength has been reduced with higher NCGs penetration. A number of indices have been developed to quantify system strength from the short-term voltage stability (STVS) perspective. None of the indices capture the overall performances of power systems on dynamic voltage recovery. In this paper, an improvement in one of the STVS indices namely, the Voltage Recovery Index (VRI), is proposed to overcome shortcomings in the original index. Moreover, the improved index is globalized to establish a new index defined as system voltage recovery index (VRIsys) to quantify STVS at the system level. The amended VRI and developed VRIsys are used in systematic simulations to quantify the impact and interaction of various factors that could affect system strength. The assessment was conducted using time-domain simulation with direct connected induction motors (DCIMs) and a proliferation of converter-based technologies on both the generation and load sides, namely, NCGs and Variable Speed Drives (VSDs), respectively. © 2013 IEEE.

A survey of early-career researchers in Australia

- Christian, Katherine, Johnstone, Carolyn, Larkins, Jo-ann, Wright, Wendy, Doran, Michael

  • Authors: Christian, Katherine , Johnstone, Carolyn , Larkins, Jo-ann , Wright, Wendy , Doran, Michael
  • Date: 2021
  • Type: Text , Journal article
  • Relation: eLife Vol. 10, no. (2021), p. 1-19
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  • Description: Early-career researchers (ECRs) make up a large portion of the academic workforce and their experiences often reflect the wider culture of the research system. Here we surveyed 658 ECRs working in Australia to better understand the needs and challenges faced by this community. Although most respondents indicated a ‘love of science’, many also expressed an intention to leave their research position. The responses highlight how job insecurity, workplace culture, mentorship and ‘questionable research practices’ are impacting the job satisfaction of ECRs and potentially compromising science in Australia. We also make recommendations for addressing some of these concerns. © Christian et al.

Advances in the discovery and development of anthelmintics by harnessing natural product scaffolds

- Herath, H. M. P. Dilrukshi, Taki, Aya, Sleebs, Brad, Hofmann, Andreas, Nguyen, Nghi, Preston, Sarah, Davis, Rohan, Jabbar, Abdul, Gasser, Robin

  • Authors: Herath, H. M. P. Dilrukshi , Taki, Aya , Sleebs, Brad , Hofmann, Andreas , Nguyen, Nghi , Preston, Sarah , Davis, Rohan , Jabbar, Abdul , Gasser, Robin
  • Date: 2021
  • Type: Text , Book chapter , Book Chapter
  • Relation: Advances in Parasitology p. 203-251
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  • Description: Widespread resistance to currently-used anthelmintics represents a major obstacle to controlling parasitic nematodes of livestock animals. Given the reliance on anthelmintics in many control regimens, there is a need for the continued discovery and development of new nematocides. Enabling such a focus are: (i) the major chemical diversity of natural products; (ii) the availability of curated, drug-like extract-, fraction- and/or compound-libraries from natural sources; (iii) the utility and practicality of well-established whole-worm bioassays for Haemonchus contortus—an important parasitic nematodes of livestock—to screen natural product libraries; and (iv) the availability of advanced chromatographic (HPLC), spectroscopic (NMR) and spectrometric (MS) techniques for bioassay-guided fractionation and structural elucidation. This context provides a sound basis for the identification and characterisation of anthelmintic candidates from natural sources. This chapter provides a background on the importance and impact of helminth infections/diseases, parasite control and aspects of drug discovery, and reviews recent work focused on (i) screening well-defined compound libraries to establish the methods needed for large-scale screening of natural extract libraries; (ii) discovering plant and marine extracts with nematocidal or nematostatic activity, and purifying bioactive compounds and assessing their potential for further development; and (iii) synthesising analogues of selected purified natural compounds for the identification of possible ‘lead’ candidates. The chapter describes some lessons learned from this work and proposes future areas of focus for drug discovery. Collectively, the findings from this recent work show potential for selected natural product scaffolds as candidates for future development. Developing such candidates via future chemical optimisation, efficacy and safety evaluations, broad spectrum activity assessments, and target identification represents an exciting prospect and, if successful, could pave the way to subsequent pre-clinical and clinical evaluations. © 2021 Elsevier Ltd

After work? Understanding older women’s portfolio life transitions

- Taylor, Philip, Earl, Catherine, Brooke, Elizabeth, McLoughlin, Christopher

  • Authors: Taylor, Philip , Earl, Catherine , Brooke, Elizabeth , McLoughlin, Christopher
  • Date: 2021
  • Type: Text , Book chapter
  • Relation: Retiring women : work and post work transitions Chapter 7 p. 111-119
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  • Description: Chapter 7 reports qualitative interviews with older women about the pursuit of an active, fulfilling and productive retirement, and the mechanisms that promote these outcomes. Contrary to notions of the blended lifecycle, analysis reveals a stark division between paid work and retirement for many women at the same time as an ongoing commitment to socially valued and productive albeit unpaid activities that form a portfolio career. Furthermore , analysis reveals an increased sense of autonomy and control over decision making among retired women that contrasts with their experiences of paid employment.

Aggregate subgradient method for nonsmooth DC optimization

- Bagirov, Adil, Taheri, Sona, Joki, Kaisa, Karmitsa, Napsu, Mäkelä, Marko

  • Authors: Bagirov, Adil , Taheri, Sona , Joki, Kaisa , Karmitsa, Napsu , Mäkelä, Marko
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Optimization Letters Vol. 15, no. 1 (2021), p. 83-96
  • Relation: http://purl.org/au-research/grants/arc/DP190100580
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  • Description: The aggregate subgradient method is developed for solving unconstrained nonsmooth difference of convex (DC) optimization problems. The proposed method shares some similarities with both the subgradient and the bundle methods. Aggregate subgradients are defined as a convex combination of subgradients computed at null steps between two serious steps. At each iteration search directions are found using only two subgradients: the aggregate subgradient and a subgradient computed at the current null step. It is proved that the proposed method converges to a critical point of the DC optimization problem and also that the number of null steps between two serious steps is finite. The new method is tested using some academic test problems and compared with several other nonsmooth DC optimization solvers. © 2020, Springer-Verlag GmbH Germany, part of Springer Nature.

Agile ageing – A modifiable vital sign to mitigate the risk of falls in older adults?

- Ogilvie, Madeleine, Wallen, Matthew, Talpey, Scott

  • Authors: Ogilvie, Madeleine , Wallen, Matthew , Talpey, Scott
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Medical Hypotheses Vol. 148, no. (2021), p.
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  • Description: Falls prevention in older adults is a targeted priority because a fall can lead to disability, institutionalisation and presents a signficant financial burden. Falls are multifactoral in nature however, impairments in both physical and cognitive functioning have been linked to their occurrence. Currently, testing and exercise training for falls prevention focuses on physical qualities such as balance and strength. Agility is a unique physical quality that couples an individuals perceptual cognitive ability with the ability to produce a quick and accurate movement. Agility is relatively well understood in a sporting context however, its application to falls prevention has been minimal. Because a fall may occur while an individual is perceiving information from the dynamic environment around them while attempting to execute a rapid and accurate movement it is hypothesised that concepts and methods used to assess and train agility in athlete populations can be use to improve practices related to the screening and training to mitigate the risk of a fall in an older adult. © 2021

An efficient hybrid system for anomaly detection in social networks

- Rahman, Md Shafiur, Halder, Sajal, Uddin, Ashraf, Acharjee, Uzzal

  • Authors: Rahman, Md Shafiur , Halder, Sajal , Uddin, Ashraf , Acharjee, Uzzal
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Cybersecurity Vol. 4, no. 1 (2021), p.
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  • Description: Anomaly detection has been an essential and dynamic research area in the data mining. A wide range of applications including different social medias have adopted different state-of-the-art methods to identify anomaly for ensuring user’s security and privacy. The social network refers to a forum used by different groups of people to express their thoughts, communicate with each other, and share the content needed. This social networks also facilitate abnormal activities, spread fake news, rumours, misinformation, unsolicited messages, and propaganda post malicious links. Therefore, detection of abnormalities is one of the important data analysis activities for the identification of normal or abnormal users on the social networks. In this paper, we have developed a hybrid anomaly detection method named DT-SVMNB that cascades several machine learning algorithms including decision tree (C5.0), Support Vector Machine (SVM) and Naïve Bayesian classifier (NBC) for classifying normal and abnormal users in social networks. We have extracted a list of unique features derived from users’ profile and contents. Using two kinds of dataset with the selected features, the proposed machine learning model called DT-SVMNB is trained. Our model classifies users as depressed one or suicidal one in the social network. We have conducted an experiment of our model using synthetic and real datasets from social network. The performance analysis demonstrates around 98% accuracy which proves the effectiveness and efficiency of our proposed system. © 2021, The Author(s).

Ant community responses to farmland use and revegetation in a fragmented agricultural landscape

- Ng, Katherine, Nowrouzi, Somayeh, Staunton, Kyran, Barton, Philip, Driscoll, Don

  • Authors: Ng, Katherine , Nowrouzi, Somayeh , Staunton, Kyran , Barton, Philip , Driscoll, Don
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Agriculture Ecosystems & Environment Vol. 311, no. (May 2021), p. 8
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  • Description: Recent alarming losses of insects from agricultural landscapes in multiple countries around the world have brought into sharp focus the urgent need to identify ways to manage these landscapes to avoid further biodiversity decline. Identifying the drivers of insect declines, such as land use change, is critical to this effort. We examined ant communities at the interface between remnant vegetation patches and three adjoining farmland types (wheat crop, rested from cropping and restoration plantings) in a fragmented landscape in temperate Australia. We asked: do ant communities and occurrence of individual species differ between remnant patches and farmlands with more intensive farmland use (restoration plantings < rested farmlands < wheat crop)? We recorded 13,283 ants belonging to 102 species from 30 genera. Excluding 21 singletons, 27 species only occurred in remnant patches compared to ten species found only in farmlands. Ant community composition in wheat crop and rested farmlands significantly differed from their adjacent remnant patches and were more homogeneous. In contrast, ant communities from restoration plantings in farmland were not significantly different in composition from those in the adjacent remnant patch. The large, aggressive Australian meat ant (Iridomyrmex purpureus) showed significantly higher occurrence in the remnant patch than all farmland types, and we suggest that the absence of this strongly interacting species from farmlands may have contributed to biotic homogenisation. Our findings show that native vegetation provides crucial habitat resources for many ant species that are not provided by farmlands, and native plantings can, in some cases, ameliorate negative effects of farmland clearing over relatively short time scales (<7 years). Agricultural intensification that involves loss of remnant native vegetation or reduced revegetation will contribute to ongoing losses and changes to ant biodiversity in farming landscapes. However, replanting native vegetation can lead to rapid restoration, signifying a possible simple remedy to insect declines.

Assessing the conservation and enhancement value of revegetated strips on arthropod assemblages in a pasture landscape

- O'Donnell, Peter, Wright, Wendy

  • Authors: O'Donnell, Peter , Wright, Wendy
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Journal of Environmental Management Vol. 278, no. (2021), p.
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  • Description: Examining population dynamics of arthropod communities in habitats neighboring arable lands is essential to understanding how agroecosystems can be engineered to enhance ecosystem services and contribute to sustainable intensification. Arthropods comprise the bulk of faunal biomass on farms, are taxonomically diverse, and are the main drivers of many ecosystem functions. This study aimed to compare arthropod assemblages in revegetated strips of native plants and exotic pastures, and examine taxa of beneficial arthropods in revegetated strips and adjacent pasture in early spring (September 2009) and mid-summer (December 2009–January 2010) on two farms in southeastern Gippsland, Victoria, Australia. Arthropod community assemblages were distinctly different between revegetated strips and adjacent pasture with the exception of functional groups in early spring. Several taxa of beneficial arthropods including Carabidae (ground beetles) and Syrphidae (hoverflies) were of similar abundance in the two habitats. Only Formicidae (ants) were of higher abundances in revegetated strips compared to adjacent pasture in both seasons. Five of the 10 ant genera present, seven spider families and Dolichopodidae flies (long-legged flies) were found exclusively in revegetated strips. Apidae (bees) and Tachinidae (tachinid flies) had higher abundances in revegetated strips compared to 80 m into the adjacent pasture in mid-summer. Lycosidae (wolf spiders) were more abundant along the edge of revegetated strips and 20 m into adjacent pasture compared to the center (core) of revegetated strips and 80 m into pasture. These results illustrate that beneficial arthropods use revegetated strips as refugia and that revegetated strips clearly enhanced biological conservation of arthropods in pasturelands. Relevance of findings to enhanced biological control is also discussed. © 2020 Elsevier Ltd

Asset management journey for realising value from assets

- Chattopadhyay, Gopinath

Behaviour tracking : using geospatial and behaviour sequence analysis to map crime

- Keatley, David, Arntfield, Michael, Gill, Paul, Clare, Joe, Oatley, Giles, Bouhana, Noemie, Clarke, David

  • Authors: Keatley, David , Arntfield, Michael , Gill, Paul , Clare, Joe , Oatley, Giles , Bouhana, Noemie , Clarke, David
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Security Journal Vol. 34, no. 1 (2021), p. 184-201
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  • Description: Crime is a complex phenomenon. To understand the commission of crime, researchers must map both the temporal and the spatial processes involved. The current research combines a temporal method of analysis, Behaviour Sequence Analysis, with geospatial mapping, to outline a new method of integrating temporal and spatial movements of criminals. To show how the new method can be applied, a burglary scenario was used, and the movements and behaviours of a criminal tracked around the property. Results showed that combining temporal and spatial analyses allows for a clearer account of the process of a crime scene. The current method has application to a large range of other crimes and terrorist movements, for instance between cities and movements within each city. Therefore, the current research provides the foundation framework for a novel method of spatio-temporal analyses of crime. © 2019, Springer Nature Limited.

Can optimum solar radiation exposure or supplemented vitamin D intake reduce the severity of COVID-19 symptoms?

- Abraham, Joji, Dowling, Kim, Florentine, Singarayer

  • Authors: Abraham, Joji , Dowling, Kim , Florentine, Singarayer
  • Date: 2021
  • Type: Text , Journal article , Review
  • Relation: International Journal of Environmental Research and Public Health Vol. 18, no. 2 (2021), p. 1-21
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  • Description: The foremost mortality-causing symptom associated with COVID-19 is acute respiratory distress syndrome (ARDS). A significant correlation has been identified between the deficiency in vitamin D and the risk of developing ARDS. It has been suggested that if we can reduce or modify ARDS in COVID-19 patients, we may significantly reduce the severity of COVID-19 symptoms and associated mortality rates. The increased mortality of dark-skinned people, who have a reduced UV absorption capacity, may be consistent with diminished vitamin D status. The factors associated with COVID-19 mortality, such as old age, ethnicity, obesity, hypertension, cardiovascular diseases, and diabetes, are all found to be linked with vitamin D deficiency. Based on this review and as a precautionary measure, it is suggested that the adoption of appropriate and safe solar exposure and vitamin D enriched foods and supplements should be considered to reduce the possible severity of COVID-19 symptoms. Safe sun exposure is deemed beneficial globally, specifically in low and middle- income countries, as there is no cost involved. It is also noted that improved solar exposure and vitamin D levels can reduce the impact of other diseases as well, thus assisting in maintaining general human well-being. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Canonical duality theory and algorithm for solving bilevel knapsack problems with applications

- Gao, David

  • Authors: Gao, David
  • Date: 2021
  • Type: Text , Journal article
  • Relation: IEEE Transactions on Systems, Man, and Cybernetics: Systems Vol. 51, no. 2 (2021), p. 893-904
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  • Description: A novel canonical duality theory (CDT) is presented for solving general bilevel mixed integer nonlinear optimization governed by linear and quadratic knapsack problems. It shows that the challenging knapsack problems can be solved analytically in term of their canonical dual solutions. The existence and uniqueness of these analytical solutions are proved. NP-hardness of the knapsack problems is discussed. A powerful CDT algorithm combined with an alternative iteration and a volume reduction method is proposed for solving the NP-hard bilevel knapsack problems. Application is illustrated by benchmark problems in optimal topology design. The performance and novelty of the proposed method are compared with the popular commercial codes. © 2013 IEEE.

Conclusion: public policy leadership and change for women’s work and retirement

- Taylor, Philip, Earl, Catherine, Brooke, Elizabeth, McLoughlin, Christopher

  • Authors: Taylor, Philip , Earl, Catherine , Brooke, Elizabeth , McLoughlin, Christopher
  • Date: 2021
  • Type: Text , Book chapter
  • Relation: Retiring women : work and post work transitions Chapter 10 p.147-151
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  • Description: With current policy concerns about shortfalls of labour supply and effects on the social welfare system due to population ageing, there is a need to understand the factors that shape women's choices about if, when and how to retire. Recent trends indicating the increased workforce participation of women demand new policy responses to the end of careers and retirement transitions to sustain acceptable levels of participation and productivity. This book is innovative in that it will examine constellations of factors that disadvantage or advantage women's career and retirement trajectories against a backdrop of public policy efforts to extend working lives.

Customizing women’s portfolio work and ‘retirement’ careers

- Taylor, Philip, Earl, Catherine, Brooke, Elizabeth, McLoughlin, Christopher

  • Authors: Taylor, Philip , Earl, Catherine , Brooke, Elizabeth , McLoughlin, Christopher
  • Date: 2021
  • Type: Text , Book chapter
  • Relation: Retiring women : work and post work transitions Chapter 8 p. 122-134
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  • Description: Chapter 8 reports qualitative interviews with older women, drawing from the concepts of biographical work-life balance and portfolio careers. It focuses on older women who were in part-time work but who self-identified as having made a transition to retirement. Many had longstanding careers and stable networks, accrued skills and financial resources, supported a well-endowed quality of portfolio lives, whereas those who experienced ‘unbalanced’ portfolio retirement were more likely to be lacking resources from their working lives. The analysis reinforces the notion that retirement should be viewed as a process and not an event and that it is impossible to tell a single story of women's post-work transitions.

Dangerous dating in the digital age : jealousy, hostility, narcissism, and psychopathy as predictors of cyber dating abuse

- Branson, Molly, March, Evita

  • Authors: Branson, Molly , March, Evita
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Computers in Human Behavior Vol. 119, no. (2021), p.
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  • Description: Cyber Dating Abuse includes perpetration of aggressive and controlling behaviours against an intimate partner via technology. Despite the significant physical and psychological outcomes, there is a paucity in research exploring predictors of Cyber Dating Abuse. In the current study, we replicate and extend previous research by exploring the utility of jealousy, hostility, narcissism (grandiose and vulnerable), and psychopathy (primary and secondary) as predictors of Cyber Dating Abuse. Participants (N = 817; 78.2% women; Mage = 28.16, SD = 10.49) were recruited via social media and completed an online questionnaire which comprised measures of jealousy, hostility, narcissism, psychopathy, and perpetration of Cyber Dating Abuse behaviours. Results supported the hypotheses that jealousy, vulnerable narcissism, and secondary psychopathy would be significant, positive predictors of Cyber Dating Abuse perpetration. No other predictor reached significance, and gender (control variable) was also a non-significant predictor. Results are discussed through the lens of evolutionary theory and the General Aggression Model and indicate that the perpetration of Cyber Dating Abuse may be better attributed to reactive, emotional aggression, compared to proactive, instrumental aggression. These results have important clinical and practical implications and may inform management and prevention of online intimate partner abuse and violence. © 2021 Elsevier Ltd

Detecting outlier patterns with query-based artificially generated searching conditions

- Yu, Shuo, Xia, Feng, Sun, Yuchen, Tang, Tao, Yan, Xiaoran, Lee, Ivan

  • Authors: Yu, Shuo , Xia, Feng , Sun, Yuchen , Tang, Tao , Yan, Xiaoran , Lee, Ivan
  • Date: 2021
  • Type: Text , Journal article
  • Relation: IEEE Transactions on Computational Social Systems Vol. 8, no. 1 (2021), p. 134-147
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  • Description: In the age of social computing, finding interesting network patterns or motifs is significant and critical for various areas, such as decision intelligence, intrusion detection, medical diagnosis, social network analysis, fake news identification, and national security. However, subgraph matching remains a computationally challenging problem, let alone identifying special motifs among them. This is especially the case in large heterogeneous real-world networks. In this article, we propose an efficient solution for discovering and ranking human behavior patterns based on network motifs by exploring a user's query in an intelligent way. Our method takes advantage of the semantics provided by a user's query, which in turn provides the mathematical constraint that is crucial for faster detection. We propose an approach to generate query conditions based on the user's query. In particular, we use meta paths between the nodes to define target patterns as well as their similarities, leading to efficient motif discovery and ranking at the same time. The proposed method is examined in a real-world academic network using different similarity measures between the nodes. The experiment result demonstrates that our method can identify interesting motifs and is robust to the choice of similarity measures. © 2014 IEEE.

Draft genome sequences of four citrobacter isolates recovered from wild australian shorebirds

- Smith, Hannah, Bean, David, Pitchers, William, Valcanis, Mary, Clarke, Rohan, Loyn, Richard, Hassell, Chris, Greenhill, Andrew

  • Authors: Smith, Hannah , Bean, David , Pitchers, William , Valcanis, Mary , Clarke, Rohan , Loyn, Richard , Hassell, Chris , Greenhill, Andrew
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Microbiology Resource Announcements Vol. 10, no. 1 (2021), p.
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  • Description: Citrobacter is a ubiquitous bacterial genus whose members inhabit a variety of niches. Some species are clinically important for both antimicrobial resistance (AMR) carriage and as the cause of nosocomial infections. Surveillance of Citrobacter species in the environment can provide indicators of the spread of AMR genes outside clinical spaces. In this study, we present draft genome sequences of four Citrobacter isolates obtained from three species of wild Australian shorebirds. Copyright © 2021 Smith et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.