A 90 minute soccer match induces eccentric hamstring muscles fatigue
- Kakavas, Georgios, Malliaropoulos, Nikos, Gabbett, Tim, Mitrotasios, Michalis, Van Dyk, Nicol, Bikos, Georgios, Maffulli, Nicola
- Authors: Kakavas, Georgios , Malliaropoulos, Nikos , Gabbett, Tim , Mitrotasios, Michalis , Van Dyk, Nicol , Bikos, Georgios , Maffulli, Nicola
- Date: 2021
- Type: Text , Journal article
- Relation: Muscles, Ligaments and Tendons Journal Vol. 11, no. 2 (2021), p. 318-323
- Full Text:
- Reviewed:
- Description: Background/Purpose of the study. Hamstring injuries are the most prevalent muscle injuries in both amateur and professional soccer (football) players. Eccentric strength deficits and muscle strength imbalances have been associated with an increased risk of muscle injuries. The current study is a non-randomised observational study investigating whether fatigue significantly reduces peak eccentric strength of the hamstring muscle group. Methods. Twenty-two right leg dominant professional football players participated in this study. None were injured or were rehabilitating from an injury at the time of testing. The eccentric strength of the hamstring muscles was determined using the Nordic exercise on a Norbord device prior to a 90 minute soccer match and after its end. Results. There was a significant decrease in eccentric strength at the end of the match (before the match: M = 306.91, SD = 59.26; after the match: Mean = 277.77 ± SD = 60.35 p =.000, Cohen’s d =.50). The imbalance in eccentric hamstring muscle strength between dominant and non-dominant limb before the match remained unchanged after its end. Conclusions. A professional football match significantly impacts on the ability of players to produce high speed eccentric strength in the hamstring muscle groups. Resistance to fatigue and eccentric strength, particularly at high speeds, are considerable factors in conditioning of professional soccer players. Eccentric muscle strength fatigue of the hamstring muscle group after a 90 min soccer match may provide a possible explanation for the greater risk of hamstring injuries under fatigue conditions. © 2021, CIC Edizioni Internazionali s.r.l.. All rights reserved.
- Authors: Kakavas, Georgios , Malliaropoulos, Nikos , Gabbett, Tim , Mitrotasios, Michalis , Van Dyk, Nicol , Bikos, Georgios , Maffulli, Nicola
- Date: 2021
- Type: Text , Journal article
- Relation: Muscles, Ligaments and Tendons Journal Vol. 11, no. 2 (2021), p. 318-323
- Full Text:
- Reviewed:
- Description: Background/Purpose of the study. Hamstring injuries are the most prevalent muscle injuries in both amateur and professional soccer (football) players. Eccentric strength deficits and muscle strength imbalances have been associated with an increased risk of muscle injuries. The current study is a non-randomised observational study investigating whether fatigue significantly reduces peak eccentric strength of the hamstring muscle group. Methods. Twenty-two right leg dominant professional football players participated in this study. None were injured or were rehabilitating from an injury at the time of testing. The eccentric strength of the hamstring muscles was determined using the Nordic exercise on a Norbord device prior to a 90 minute soccer match and after its end. Results. There was a significant decrease in eccentric strength at the end of the match (before the match: M = 306.91, SD = 59.26; after the match: Mean = 277.77 ± SD = 60.35 p =.000, Cohen’s d =.50). The imbalance in eccentric hamstring muscle strength between dominant and non-dominant limb before the match remained unchanged after its end. Conclusions. A professional football match significantly impacts on the ability of players to produce high speed eccentric strength in the hamstring muscle groups. Resistance to fatigue and eccentric strength, particularly at high speeds, are considerable factors in conditioning of professional soccer players. Eccentric muscle strength fatigue of the hamstring muscle group after a 90 min soccer match may provide a possible explanation for the greater risk of hamstring injuries under fatigue conditions. © 2021, CIC Edizioni Internazionali s.r.l.. All rights reserved.
A qualitative analysis of the perceived determinants of success in elite esports athletes
- Poulus, Dylan, Coulter, Tristan, Trotter, Michael, Polman, Remco
- Authors: Poulus, Dylan , Coulter, Tristan , Trotter, Michael , Polman, Remco
- Date: 2022
- Type: Text , Journal article
- Relation: Journal of Sports Sciences Vol. 40, no. 7 (2022), p. 742-753
- Full Text:
- Reviewed:
- Description: The current study aimed to qualitatively investigate the perceived determinants of success in professional esports athletes. Guided by the bioecological model (Bronfenbrenner & Morris, 2006), thematic analysis was used to explore elite esports athletes’ perceptions of success determinants. Semi-structured interviews were conducted with seven elite esports athletes. The interviews were used to investigate players’ psychology when playing well, training in elite esports, and working in esports teams. Deductive and inductive analyses were conducted to capture the core themes of success in esports within the bioecological model. When playing well, elite esports athletes experienced high levels of confidence, uninterrupted focus, and flow states. Elite esport athletes use mental strategies to help regulate their emotions and remain mindful in the presence of “tilt”. Furthermore, breathing techniques and tactical breaks were used when players felt nervous or when trying to “reset” from a stressful situation. When working in elite esport teams, players reported using strategies to improve team cohesion and that the biggest challenge was interpersonal disagreements. The results contribute to the growing body of literature highlighting the psychological similarities between elite esports and traditional sports athletes and serve as an index for future research into high-performance in esports. © 2021 Informa UK Limited, trading as Taylor & Francis Group.
- Authors: Poulus, Dylan , Coulter, Tristan , Trotter, Michael , Polman, Remco
- Date: 2022
- Type: Text , Journal article
- Relation: Journal of Sports Sciences Vol. 40, no. 7 (2022), p. 742-753
- Full Text:
- Reviewed:
- Description: The current study aimed to qualitatively investigate the perceived determinants of success in professional esports athletes. Guided by the bioecological model (Bronfenbrenner & Morris, 2006), thematic analysis was used to explore elite esports athletes’ perceptions of success determinants. Semi-structured interviews were conducted with seven elite esports athletes. The interviews were used to investigate players’ psychology when playing well, training in elite esports, and working in esports teams. Deductive and inductive analyses were conducted to capture the core themes of success in esports within the bioecological model. When playing well, elite esports athletes experienced high levels of confidence, uninterrupted focus, and flow states. Elite esport athletes use mental strategies to help regulate their emotions and remain mindful in the presence of “tilt”. Furthermore, breathing techniques and tactical breaks were used when players felt nervous or when trying to “reset” from a stressful situation. When working in elite esport teams, players reported using strategies to improve team cohesion and that the biggest challenge was interpersonal disagreements. The results contribute to the growing body of literature highlighting the psychological similarities between elite esports and traditional sports athletes and serve as an index for future research into high-performance in esports. © 2021 Informa UK Limited, trading as Taylor & Francis Group.
A qualitative exploration of the impact of knowledge and perceptions about hypertension in medication adherence in Middle Eastern refugees and migrants
- Shahin, Wejdan, Kennedy, Gerard, Stupans, Ieva
- Authors: Shahin, Wejdan , Kennedy, Gerard , Stupans, Ieva
- Date: 2021
- Type: Text , Journal article
- Relation: Exploratory Research in Clinical and Social Pharmacy Vol. 3, no. (2021), p. 100038-100038
- Full Text:
- Reviewed:
- Description: Knowledge and perceptions about chronic disease and medications play a crucial role in determining long-term treatment adherence to diseases such as hypertension. Exploring in depth the barriers and enablers to medication adherence in specific population subgroups such as Middle Eastern refugees and migrants in Australia is important. This may provide a better understanding of each of these groups' beliefs and knowledge and suggest strategies and interventions to improve medication adherence. This study aimed to understand Middle Eastern refugees' and migrants' experiences, perceptions, and knowledge about hypertension and to explore factors affecting medication adherence. In this study 15 participants who identified themselves as Middle Eastern refugees and migrants in Australia and had been diagnosed with hypertension were interviewed (migrants = 5, refugees =10) using semi-structured interviews. Recorded interviews were analysed using a thematic analysis framework and the findings were reported according to consolidated criteria for reporting qualitative research. Three key themes emerged from the interview analysis: (1) dealing with the illness in terms of understanding the symptoms and causes, self-managing of high blood pressure, and coping and acquaintance with the illness (2) beliefs, practices around medication adherence and the barriers and facilitators to taking medications regularly and (3) healthcare encounters represented by participants trust in healthcare providers. Differences were found between refugees and migrants relating to the understanding, control, and coping with hypertension, beliefs about medications, trust of healthcare providers, and taking medications as prescribed. There were also differences in the social context of the two groups. Understanding the factors that prevent adherence to hypertension in Middle Eastern refugees addressed the gap in the literature regarding refugees' beliefs and medication adherence. Future studies are recommended to assess the improvement in medication adherence in refugees by modifying their beliefs, attitude, and knowledge about medications and illness. In addition, healthcare providers should consider the differences between Middle Eastern refugees and migrants when providing the health advice that targets each of these population independently to ultimately improve their overall health and adherence to medications. Erratum: The publisher regrets that the section below was accidentally anonymized in the original published version of this article: “Ethical approval was obtained from (redacted) 60–19/22299”. This section should read: “Ethical approval was obtained from RMIT University Ethics Committee 60–19/22299”. The publisher would like to apologise for any inconvenience caused.
- Authors: Shahin, Wejdan , Kennedy, Gerard , Stupans, Ieva
- Date: 2021
- Type: Text , Journal article
- Relation: Exploratory Research in Clinical and Social Pharmacy Vol. 3, no. (2021), p. 100038-100038
- Full Text:
- Reviewed:
- Description: Knowledge and perceptions about chronic disease and medications play a crucial role in determining long-term treatment adherence to diseases such as hypertension. Exploring in depth the barriers and enablers to medication adherence in specific population subgroups such as Middle Eastern refugees and migrants in Australia is important. This may provide a better understanding of each of these groups' beliefs and knowledge and suggest strategies and interventions to improve medication adherence. This study aimed to understand Middle Eastern refugees' and migrants' experiences, perceptions, and knowledge about hypertension and to explore factors affecting medication adherence. In this study 15 participants who identified themselves as Middle Eastern refugees and migrants in Australia and had been diagnosed with hypertension were interviewed (migrants = 5, refugees =10) using semi-structured interviews. Recorded interviews were analysed using a thematic analysis framework and the findings were reported according to consolidated criteria for reporting qualitative research. Three key themes emerged from the interview analysis: (1) dealing with the illness in terms of understanding the symptoms and causes, self-managing of high blood pressure, and coping and acquaintance with the illness (2) beliefs, practices around medication adherence and the barriers and facilitators to taking medications regularly and (3) healthcare encounters represented by participants trust in healthcare providers. Differences were found between refugees and migrants relating to the understanding, control, and coping with hypertension, beliefs about medications, trust of healthcare providers, and taking medications as prescribed. There were also differences in the social context of the two groups. Understanding the factors that prevent adherence to hypertension in Middle Eastern refugees addressed the gap in the literature regarding refugees' beliefs and medication adherence. Future studies are recommended to assess the improvement in medication adherence in refugees by modifying their beliefs, attitude, and knowledge about medications and illness. In addition, healthcare providers should consider the differences between Middle Eastern refugees and migrants when providing the health advice that targets each of these population independently to ultimately improve their overall health and adherence to medications. Erratum: The publisher regrets that the section below was accidentally anonymized in the original published version of this article: “Ethical approval was obtained from (redacted) 60–19/22299”. This section should read: “Ethical approval was obtained from RMIT University Ethics Committee 60–19/22299”. The publisher would like to apologise for any inconvenience caused.
A suggested new term and definition to describe the cumulative physiological and functional effects of non-injurious head impacts
- Lavender, Andrew, Georgieva, Julia, Takechi, Ryusuke
- Authors: Lavender, Andrew , Georgieva, Julia , Takechi, Ryusuke
- Date: 2022
- Type: Text , Journal article
- Relation: Frontiers in Neurology Vol. 13, no. (2022), p.
- Full Text:
- Reviewed:
- Authors: Lavender, Andrew , Georgieva, Julia , Takechi, Ryusuke
- Date: 2022
- Type: Text , Journal article
- Relation: Frontiers in Neurology Vol. 13, no. (2022), p.
- Full Text:
- Reviewed:
A validated injury surveillance and monitoring tool for fast jet aircrew: Translating sports medicine paradigms to a military population
- Wallace, James, Osmotherly, Peter, Gabbett, Tim, Spratford, Wayne, Niyonsenga, Theo, Newman, Phil
- Authors: Wallace, James , Osmotherly, Peter , Gabbett, Tim , Spratford, Wayne , Niyonsenga, Theo , Newman, Phil
- Date: 2022
- Type: Text , Journal article
- Relation: Sports medicine - open Vol. 8, no. 1 (2022), p.
- Full Text:
- Reviewed:
- Description: Background Military populations, including fast jet aircrew (FJA - aka fighter aircrew/pilots), commonly suffer from musculoskeletal complaints, which reduce performance and operational capability. Valid surveillance tools and agreed recordable injury definitions are lacking. Our objective was to develop and then evaluate the validity of a musculoskeletal complaints surveillance and monitoring tool for FJA. Methods A Delphi study with international experts sought consensus on recordable injury definitions and important content for use in a surveillance and monitoring tool for FJA. Using these results and feedback from end-users (FJA), the University of Canberra Fast Jet Aircrew Musculoskeletal Questionnaire (UC-FJAMQ) was developed. Following its use with 306 Royal Australian Air Force (RAAF) FJA over 4 × five-month reporting periods, validity of the UC-FJAMQ was evaluated via multi-level factor analysis (MFA) and compared with routine methods of injury surveillance. Results Consensus was achieved for: eight words/descriptors for defining a musculoskeletal complaint six definitions of recordable injury and 14 domains important for determining overall severity. The UC-FJAMQ was developed and refined. MFA identified three distinct dimensions within the 11 items used to determine severity: operational capability, symptoms, and care-seeking. MFA further highlighted that symptom severity and seeking medical attention were poor indicators of the impact musculoskeletal complaints have upon operational capability. One hundred and fifty-two episodes of time loss were identified, with the UC-FJAMQ identifying 79% of these, while routine methods identified 49%. Despite modest weekly reporting rates (61%), the UC-FJAMQ outperformed routine surveillance methods. Conclusions The UC-FJAMQ was developed to specifically address the complexities of injury surveillance with FJA, which are similar to those noted in other military and sporting populations. The results demonstrated the UC-FJAMQ to be sensitive and valid within a large group of FJA over 4 × five-month reporting periods. Adoption of consistent, sensitive, and valid surveillance methods will strengthen the FJA injury prevention literature, ultimately enhancing their health, performance, and operational capability.
- Authors: Wallace, James , Osmotherly, Peter , Gabbett, Tim , Spratford, Wayne , Niyonsenga, Theo , Newman, Phil
- Date: 2022
- Type: Text , Journal article
- Relation: Sports medicine - open Vol. 8, no. 1 (2022), p.
- Full Text:
- Reviewed:
- Description: Background Military populations, including fast jet aircrew (FJA - aka fighter aircrew/pilots), commonly suffer from musculoskeletal complaints, which reduce performance and operational capability. Valid surveillance tools and agreed recordable injury definitions are lacking. Our objective was to develop and then evaluate the validity of a musculoskeletal complaints surveillance and monitoring tool for FJA. Methods A Delphi study with international experts sought consensus on recordable injury definitions and important content for use in a surveillance and monitoring tool for FJA. Using these results and feedback from end-users (FJA), the University of Canberra Fast Jet Aircrew Musculoskeletal Questionnaire (UC-FJAMQ) was developed. Following its use with 306 Royal Australian Air Force (RAAF) FJA over 4 × five-month reporting periods, validity of the UC-FJAMQ was evaluated via multi-level factor analysis (MFA) and compared with routine methods of injury surveillance. Results Consensus was achieved for: eight words/descriptors for defining a musculoskeletal complaint six definitions of recordable injury and 14 domains important for determining overall severity. The UC-FJAMQ was developed and refined. MFA identified three distinct dimensions within the 11 items used to determine severity: operational capability, symptoms, and care-seeking. MFA further highlighted that symptom severity and seeking medical attention were poor indicators of the impact musculoskeletal complaints have upon operational capability. One hundred and fifty-two episodes of time loss were identified, with the UC-FJAMQ identifying 79% of these, while routine methods identified 49%. Despite modest weekly reporting rates (61%), the UC-FJAMQ outperformed routine surveillance methods. Conclusions The UC-FJAMQ was developed to specifically address the complexities of injury surveillance with FJA, which are similar to those noted in other military and sporting populations. The results demonstrated the UC-FJAMQ to be sensitive and valid within a large group of FJA over 4 × five-month reporting periods. Adoption of consistent, sensitive, and valid surveillance methods will strengthen the FJA injury prevention literature, ultimately enhancing their health, performance, and operational capability.
Adjustment for body mass index changes inverse associations of HDL-cholesterol with blood pressure and hypertension to positive associations
- Yang, Guang, Qian, Tingting, Sun, Hui, Xu, Qun, Hou, Xujuan, Hu, Wenqi, Zhang, Guang, Drummond, Grant, Sobey, Christopher, Witting, Paul, Denton, Kate, Charchar, Fadi, Golledge, Jonathan, Wang, Yutang
- Authors: Yang, Guang , Qian, Tingting , Sun, Hui , Xu, Qun , Hou, Xujuan , Hu, Wenqi , Zhang, Guang , Drummond, Grant , Sobey, Christopher , Witting, Paul , Denton, Kate , Charchar, Fadi , Golledge, Jonathan , Wang, Yutang
- Date: 2022
- Type: Text , Journal article
- Relation: Journal of Human Hypertension Vol. 36, no. 6 (2022), p. 570-579
- Relation: https://purl.org/au-research/grants/nhmrc/1062671
- Full Text:
- Reviewed:
- Description: The associations between high-density lipoprotein cholesterol (HDL-C) and blood pressure (BP) or hypertension are inconsistent in previous studies. This study aimed to assess these associations in a large cohort of Chinese adults and across different age groups. This cross-sectional association study included 22,081 Chinese adults. Associations of HDL-C with BP and hypertension were analyzed using linear or logistic regression, with or without adjustment for confounding factors. HDL-C was inversely associated with BP and hypertension. These associations were still apparent after adjustment for age, sex, fasting plasma glucose, and low-density lipoprotein cholesterol. Sub-analyses revealed: (1) in the whole cohort and females alone, HDL-C was inversely associated with BP and hypertension in young and middle-aged but not older participants; (2) in males alone, HDL-C was not associated with systolic BP or hypertension. However, HDL-C was either inversely, or not, or positively associated with BP in young, middle-aged, and older males, respectively. After further adjustment for body mass index (BMI), the negative associations of HDL-C with BP and hypertension in the whole cohort became positive ones, and the positive associations only presented in males. These findings suggest that further adjustment for BMI changes inverse associations of HDL-cholesterol with BP and hypertension to positive associations in a cohort of Chinese adults. © 2021, The Author(s), under exclusive licence to Springer Nature Limited.
- Authors: Yang, Guang , Qian, Tingting , Sun, Hui , Xu, Qun , Hou, Xujuan , Hu, Wenqi , Zhang, Guang , Drummond, Grant , Sobey, Christopher , Witting, Paul , Denton, Kate , Charchar, Fadi , Golledge, Jonathan , Wang, Yutang
- Date: 2022
- Type: Text , Journal article
- Relation: Journal of Human Hypertension Vol. 36, no. 6 (2022), p. 570-579
- Relation: https://purl.org/au-research/grants/nhmrc/1062671
- Full Text:
- Reviewed:
- Description: The associations between high-density lipoprotein cholesterol (HDL-C) and blood pressure (BP) or hypertension are inconsistent in previous studies. This study aimed to assess these associations in a large cohort of Chinese adults and across different age groups. This cross-sectional association study included 22,081 Chinese adults. Associations of HDL-C with BP and hypertension were analyzed using linear or logistic regression, with or without adjustment for confounding factors. HDL-C was inversely associated with BP and hypertension. These associations were still apparent after adjustment for age, sex, fasting plasma glucose, and low-density lipoprotein cholesterol. Sub-analyses revealed: (1) in the whole cohort and females alone, HDL-C was inversely associated with BP and hypertension in young and middle-aged but not older participants; (2) in males alone, HDL-C was not associated with systolic BP or hypertension. However, HDL-C was either inversely, or not, or positively associated with BP in young, middle-aged, and older males, respectively. After further adjustment for body mass index (BMI), the negative associations of HDL-C with BP and hypertension in the whole cohort became positive ones, and the positive associations only presented in males. These findings suggest that further adjustment for BMI changes inverse associations of HDL-cholesterol with BP and hypertension to positive associations in a cohort of Chinese adults. © 2021, The Author(s), under exclusive licence to Springer Nature Limited.
Agile ageing : implementation considerations for a walking basketball program
- Talpey, Scott, Pascoe, Deborah, Wallen, Mathew
- Authors: Talpey, Scott , Pascoe, Deborah , Wallen, Mathew
- Date: 2023
- Type: Text , Journal article
- Relation: Activities, Adaptation and Aging Vol. 47, no. 3 (2023), p. 301-314
- Full Text:
- Reviewed:
- Description: Physical activity generally declines with increasing age and lack of enjoyment is a noted barrier to older adults participating in traditional exercise programs. Walking basketball is a modified version of basketball designed to align with the physical capabilities of older adults, where participants are required to walk rather than run and body contact is not allowed. A walking basketball program provides participants with an opportunity to obtain the physical, mental and social health benefits of exercise in a competitive and social context. Due to the dynamic environment of a walking basketball program, participants are exposed to a unique stimulus combining both physical and cognitive demands, that is unmatched by traditional exercise programs. However, an increased risk of injury coincides with the unique demands of the activity. Therefore, the purpose of this manuscript is to provide practical applications for sporting organization that wish to implement a walking basketball program. © 2022 Taylor & Francis Group, LLC.
- Authors: Talpey, Scott , Pascoe, Deborah , Wallen, Mathew
- Date: 2023
- Type: Text , Journal article
- Relation: Activities, Adaptation and Aging Vol. 47, no. 3 (2023), p. 301-314
- Full Text:
- Reviewed:
- Description: Physical activity generally declines with increasing age and lack of enjoyment is a noted barrier to older adults participating in traditional exercise programs. Walking basketball is a modified version of basketball designed to align with the physical capabilities of older adults, where participants are required to walk rather than run and body contact is not allowed. A walking basketball program provides participants with an opportunity to obtain the physical, mental and social health benefits of exercise in a competitive and social context. Due to the dynamic environment of a walking basketball program, participants are exposed to a unique stimulus combining both physical and cognitive demands, that is unmatched by traditional exercise programs. However, an increased risk of injury coincides with the unique demands of the activity. Therefore, the purpose of this manuscript is to provide practical applications for sporting organization that wish to implement a walking basketball program. © 2022 Taylor & Francis Group, LLC.
Analysis of the impact of sex and age on the variation in the prevalence of antinuclear autoantibodies in Polish population : a nationwide observational, cross-sectional study
- Krzemie, Kasperczyk, Sławomir, Banach, Maciej, Kasperczyk, Aleksandra, Dobrakowski, Michał, Tomasik, Tomasz, Windak, Adam, Mastej, Mirosław, Catapano, Alberico, Ray, Kausik, Mikhailidis, Dimitri, Toth, Peter, Howard, George, Lip, Gregory, Tomaszewski, Macie, Charchar, Fadi, Sattar, Naveed, Williams, Bryan, MacDonald, Thomas, Penson, Peter, Al-Shaer, B, Andrusewicz, W., Anusz-Gaszewska, E., Balawajder, P., Bańka, G., Barańska-Skubisz E., Przyczyna, B., Bartkowiak S.
- Authors: Krzemie , Kasperczyk, Sławomir , Banach, Maciej , Kasperczyk, Aleksandra , Dobrakowski, Michał , Tomasik, Tomasz , Windak, Adam , Mastej, Mirosław , Catapano, Alberico , Ray, Kausik , Mikhailidis, Dimitri , Toth, Peter , Howard, George , Lip, Gregory , Tomaszewski, Macie , Charchar, Fadi , Sattar, Naveed , Williams, Bryan , MacDonald, Thomas , Penson, Peter , Al-Shaer, B , Andrusewicz, W. , Anusz-Gaszewska, E. , Balawajder, P. , Bańka, G. , Barańska-Skubisz E. , Przyczyna, B. , Bartkowiak S.
- Date: 2022
- Type: Text , Journal article
- Relation: Rheumatology International Vol. 42, no. 2 (2022), p. 261-271
- Full Text:
- Reviewed:
- Description: The detection of antinuclear autoantibody (ANA) is dependent on many factors and varies between the populations. The aim of the study was first to assess the prevalence of ANA in the Polish adult population depending on age, sex and the cutoff threshold used for the results obtained. Second, we estimated the occurrence of individual types of ANA-staining patterns. We tested 1731 patient samples using commercially available IIFA using two cutoff thresholds of 1:100 and 1:160. We found ANA in 260 participants (15.0%), but the percentage of positive results strongly depended on the cutoff level. For a cutoff threshold 1:100, the positive population was 19.5% and for the 1:160 cutoff threshold, it was 11.7%. The most prevalent ANA-staining pattern was AC-2 Dense Fine speckled (50%), followed by AC-21 Reticular/AMA (14.38%) ANA more common in women (72%); 64% of ANA-positive patients were over 50 years of age. ANA prevalence in the Polish population is at a level observed in other highly developed countries and is more prevalent in women and elderly individuals. To reduce the number of positive results released, we suggest that Polish laboratories should set 1:160 as the cutoff threshold. © 2021, The Author(s). **Please note that there are multiple authors for this article therefore only the name of the first 30 including Federation University Australia affiliate “Fadi Charchar" is provided in this record**
- Authors: Krzemie , Kasperczyk, Sławomir , Banach, Maciej , Kasperczyk, Aleksandra , Dobrakowski, Michał , Tomasik, Tomasz , Windak, Adam , Mastej, Mirosław , Catapano, Alberico , Ray, Kausik , Mikhailidis, Dimitri , Toth, Peter , Howard, George , Lip, Gregory , Tomaszewski, Macie , Charchar, Fadi , Sattar, Naveed , Williams, Bryan , MacDonald, Thomas , Penson, Peter , Al-Shaer, B , Andrusewicz, W. , Anusz-Gaszewska, E. , Balawajder, P. , Bańka, G. , Barańska-Skubisz E. , Przyczyna, B. , Bartkowiak S.
- Date: 2022
- Type: Text , Journal article
- Relation: Rheumatology International Vol. 42, no. 2 (2022), p. 261-271
- Full Text:
- Reviewed:
- Description: The detection of antinuclear autoantibody (ANA) is dependent on many factors and varies between the populations. The aim of the study was first to assess the prevalence of ANA in the Polish adult population depending on age, sex and the cutoff threshold used for the results obtained. Second, we estimated the occurrence of individual types of ANA-staining patterns. We tested 1731 patient samples using commercially available IIFA using two cutoff thresholds of 1:100 and 1:160. We found ANA in 260 participants (15.0%), but the percentage of positive results strongly depended on the cutoff level. For a cutoff threshold 1:100, the positive population was 19.5% and for the 1:160 cutoff threshold, it was 11.7%. The most prevalent ANA-staining pattern was AC-2 Dense Fine speckled (50%), followed by AC-21 Reticular/AMA (14.38%) ANA more common in women (72%); 64% of ANA-positive patients were over 50 years of age. ANA prevalence in the Polish population is at a level observed in other highly developed countries and is more prevalent in women and elderly individuals. To reduce the number of positive results released, we suggest that Polish laboratories should set 1:160 as the cutoff threshold. © 2021, The Author(s). **Please note that there are multiple authors for this article therefore only the name of the first 30 including Federation University Australia affiliate “Fadi Charchar" is provided in this record**
Buffering the fear of COVID-19 : social connectedness mediates the relationship between fear of COVID-19 and psychological wellbeing
- Humphrey, Ashley, March, Evita, Lavender, Andrew, Miller, Kyle, Alvarenga, Marlies, Mesagno, Christopher
- Authors: Humphrey, Ashley , March, Evita , Lavender, Andrew , Miller, Kyle , Alvarenga, Marlies , Mesagno, Christopher
- Date: 2022
- Type: Text , Journal article
- Relation: Behavioral Sciences Vol. 12, no. 3 (2022), p.
- Full Text:
- Reviewed:
- Description: Social connections are crucial for an individual’s health, wellbeing, and overall effective functioning. During the COVID-19 pandemic, one major preventative effort for reducing the spread of COVID-19 involved restricting people’s typical social interactions through physical distancing and isolation. The current cross-sectional study, conducted during the COVID-19 pandemic, explored the relationship among fear of COVID-19, social connectedness, resilience, depressive symptomologies, and self-perceived stress. Participants (N = 174) completed an anonymous, online questionnaire, and results indicated that social connectedness mediated the relationship between fear of COVID-19 and psychological wellbeing. In contrast, the relationship between fear of COVID-19 and psychological wellbeing was not mediated by resilience. These findings highlight the important role that social connections and resilience play in buffering against negative psychological wellbeing outcomes, especially during a pandemic. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
- Authors: Humphrey, Ashley , March, Evita , Lavender, Andrew , Miller, Kyle , Alvarenga, Marlies , Mesagno, Christopher
- Date: 2022
- Type: Text , Journal article
- Relation: Behavioral Sciences Vol. 12, no. 3 (2022), p.
- Full Text:
- Reviewed:
- Description: Social connections are crucial for an individual’s health, wellbeing, and overall effective functioning. During the COVID-19 pandemic, one major preventative effort for reducing the spread of COVID-19 involved restricting people’s typical social interactions through physical distancing and isolation. The current cross-sectional study, conducted during the COVID-19 pandemic, explored the relationship among fear of COVID-19, social connectedness, resilience, depressive symptomologies, and self-perceived stress. Participants (N = 174) completed an anonymous, online questionnaire, and results indicated that social connectedness mediated the relationship between fear of COVID-19 and psychological wellbeing. In contrast, the relationship between fear of COVID-19 and psychological wellbeing was not mediated by resilience. These findings highlight the important role that social connections and resilience play in buffering against negative psychological wellbeing outcomes, especially during a pandemic. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
Can the workload–injury relationship be moderated by improved strength, speed and repeated-sprint qualities?
- Malone, Shane, Hughes, Brian, Doran, Dominic, Collins, Kieran, Gabbett, Tim
- Authors: Malone, Shane , Hughes, Brian , Doran, Dominic , Collins, Kieran , Gabbett, Tim
- Date: 2019
- Type: Text , Journal article
- Relation: Journal of Science and Medicine in Sport Vol. 22, no. 1 (2019), p. 29-34
- Full Text:
- Reviewed:
- Description: Objectives: The aim of this study was to investigate potential moderators (i.e. lower body strength, repeated-sprint ability [RSA] and maximal velocity) of injury risk within a team-sport cohort. Design: Observational cohort study. Methods: Forty male amateur hurling players (age: 26.2 ± 4.4 year, height: 184.2 ± 7.1 cm, mass: 82.6 ± 4.7 kg) were recruited. During a two-year period, workload (session RPE × duration), injury and physical qualities were assessed. Specific physical qualities assessed were a three-repetition maximum Trapbar deadlift, 6 × 35-m repeated-sprint (RSA) and 5-, 10- and 20-m sprint time. All derived workload and physical quality measures were modelled against injury data using regression analysis. Odds ratios (OR) were reported against a reference group. Results: Moderate weekly loads between ≥1400 AU and ≤1900 AU were protective against injury during both the pre-season (OR: 0.44, 95% CI: 0.18–0.66) and in-season periods (OR: 0.59, 95% CI: 0.37–0.82) compared to a low load reference group (≤1200 AU). When strength was considered as a moderator of injury risk, stronger athletes were better able to tolerate the given workload at a reduced risk. Stronger athletes were also better able to tolerate larger week-to-week changes (>550–1000 AU) in workload than weaker athletes (OR = 2.54–4.52). Athletes who were slower over 5-m (OR: 3.11, 95% CI: 2.33–3.87), 10-m (OR: 3.45, 95% CI: 2.11–4.13) and 20-m (OR: 3.12, 95% CI: 2.11–4.13) were at increased risk of injury compared to faster athletes. When repeated-sprint total time (RSAt) was considered as a moderator of injury risk at a given workload (≥1750 AU), athletes with better RSAt were at reduced risk compared to those with poor RSAt (OR: 5.55, 95%: 3.98–7.94). Conclusions: These findings demonstrate that well-developed lower-body strength, RSA and speed are associated with better tolerance to higher workloads and reduced risk of injury in team-sport athletes. © 2018 Sports Medicine Australia
- Authors: Malone, Shane , Hughes, Brian , Doran, Dominic , Collins, Kieran , Gabbett, Tim
- Date: 2019
- Type: Text , Journal article
- Relation: Journal of Science and Medicine in Sport Vol. 22, no. 1 (2019), p. 29-34
- Full Text:
- Reviewed:
- Description: Objectives: The aim of this study was to investigate potential moderators (i.e. lower body strength, repeated-sprint ability [RSA] and maximal velocity) of injury risk within a team-sport cohort. Design: Observational cohort study. Methods: Forty male amateur hurling players (age: 26.2 ± 4.4 year, height: 184.2 ± 7.1 cm, mass: 82.6 ± 4.7 kg) were recruited. During a two-year period, workload (session RPE × duration), injury and physical qualities were assessed. Specific physical qualities assessed were a three-repetition maximum Trapbar deadlift, 6 × 35-m repeated-sprint (RSA) and 5-, 10- and 20-m sprint time. All derived workload and physical quality measures were modelled against injury data using regression analysis. Odds ratios (OR) were reported against a reference group. Results: Moderate weekly loads between ≥1400 AU and ≤1900 AU were protective against injury during both the pre-season (OR: 0.44, 95% CI: 0.18–0.66) and in-season periods (OR: 0.59, 95% CI: 0.37–0.82) compared to a low load reference group (≤1200 AU). When strength was considered as a moderator of injury risk, stronger athletes were better able to tolerate the given workload at a reduced risk. Stronger athletes were also better able to tolerate larger week-to-week changes (>550–1000 AU) in workload than weaker athletes (OR = 2.54–4.52). Athletes who were slower over 5-m (OR: 3.11, 95% CI: 2.33–3.87), 10-m (OR: 3.45, 95% CI: 2.11–4.13) and 20-m (OR: 3.12, 95% CI: 2.11–4.13) were at increased risk of injury compared to faster athletes. When repeated-sprint total time (RSAt) was considered as a moderator of injury risk at a given workload (≥1750 AU), athletes with better RSAt were at reduced risk compared to those with poor RSAt (OR: 5.55, 95%: 3.98–7.94). Conclusions: These findings demonstrate that well-developed lower-body strength, RSA and speed are associated with better tolerance to higher workloads and reduced risk of injury in team-sport athletes. © 2018 Sports Medicine Australia
Classifying excessive exercise : examining the relationship between compulsive exercise with obsessive-compulsive disorder symptoms and disordered eating symptoms
- Cosh, Suzanne, Eshkevari, Ertimiss, McNeil, Dominic, Tully, Phillip
- Authors: Cosh, Suzanne , Eshkevari, Ertimiss , McNeil, Dominic , Tully, Phillip
- Date: 2023
- Type: Text , Journal article
- Relation: European Eating Disorders Review Vol. 31, no. 6 (2023), p. 769-780
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- Description: Objective: There remains a lack of consensus around nosology for compulsive exercise (CE). Although widely observed in eating disorders (ED), CE shares theoretical overlap with obsessive-compulsive disorder (OCD), where exercise compulsions occur in response to obsessions. Yet, there is limited and mixed evidence of a relationship between CE with OCD. This study aims to explore the appropriate diagnostic classification of CE through examination of CE in relation to OCD, obsessional thinking, and ED symptoms. Method: Two hundred and eighty one adults with mental health symptoms, dieting, and exercise behaviour completed measures of OCD, CE, and disordered eating symptoms. Regression and Receiver Operating Characteristic analyses examined relationships between dimensions of CE with OCD and ED symptoms, and the predictive ability of CE assessment for detecting threshold OCD and ED symptoms. Results: CE assessment was poor at predicting threshold OCD symptoms, probable Anorexia Nervosa, and Binge Eating Disorder and moderate at detecting probable disordered eating and Bulimia Nervosa. Associations between CE and OCD symptoms were not significant after adjustment for ED symptoms. Obsessional thinking was associated only with lack of exercise enjoyment. Conclusions: Results indicate that excessive exercise might represent a distinct disorder, with some shared traits across CE, OCD and ED symptoms. Findings question the utility of adaptation of OCD diagnostic criteria for CE. Assessment and treatment implications are considered. © 2023 The Authors. European Eating Disorders Review published by Eating Disorders Association and John Wiley & Sons Ltd.
- Authors: Cosh, Suzanne , Eshkevari, Ertimiss , McNeil, Dominic , Tully, Phillip
- Date: 2023
- Type: Text , Journal article
- Relation: European Eating Disorders Review Vol. 31, no. 6 (2023), p. 769-780
- Full Text:
- Reviewed:
- Description: Objective: There remains a lack of consensus around nosology for compulsive exercise (CE). Although widely observed in eating disorders (ED), CE shares theoretical overlap with obsessive-compulsive disorder (OCD), where exercise compulsions occur in response to obsessions. Yet, there is limited and mixed evidence of a relationship between CE with OCD. This study aims to explore the appropriate diagnostic classification of CE through examination of CE in relation to OCD, obsessional thinking, and ED symptoms. Method: Two hundred and eighty one adults with mental health symptoms, dieting, and exercise behaviour completed measures of OCD, CE, and disordered eating symptoms. Regression and Receiver Operating Characteristic analyses examined relationships between dimensions of CE with OCD and ED symptoms, and the predictive ability of CE assessment for detecting threshold OCD and ED symptoms. Results: CE assessment was poor at predicting threshold OCD symptoms, probable Anorexia Nervosa, and Binge Eating Disorder and moderate at detecting probable disordered eating and Bulimia Nervosa. Associations between CE and OCD symptoms were not significant after adjustment for ED symptoms. Obsessional thinking was associated only with lack of exercise enjoyment. Conclusions: Results indicate that excessive exercise might represent a distinct disorder, with some shared traits across CE, OCD and ED symptoms. Findings question the utility of adaptation of OCD diagnostic criteria for CE. Assessment and treatment implications are considered. © 2023 The Authors. European Eating Disorders Review published by Eating Disorders Association and John Wiley & Sons Ltd.
Compulsive exercise and its relationship with mental health and psychosocial wellbeing in recreational exercisers and athletes
- Cosh, Suzanne, McNeil, Dominic, Tully, Phillip
- Authors: Cosh, Suzanne , McNeil, Dominic , Tully, Phillip
- Date: 2023
- Type: Text , Journal article
- Relation: Journal of Science and Medicine in Sport Vol. 26, no. 7 (2023), p. 338-344
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- Description: Objectives: Better understanding of compulsive exercise is needed in sports medicine. Whilst compulsive exercise may impact mental health, the limited research exploring the relationship between compulsive exercise and psychosocial outcomes is equivocal. The majority of studies have examined eating disorder populations where the eating disorder pathology might account for distress. This study explores relationships between compulsive exercise and mental health. Design: Cross-sectional observational study. Methods: Australian recreational exercisers and athletes (N = 1157; Mage 36.4, standard deviation = 12.9, 77 % female) recruited through sporting organisations, clubs, and gyms, completed measures of compulsive exercise, depression, anxiety, stress, life satisfaction, social physique anxiety, and self-esteem. Regression analyses examined relationships between dimensions of compulsive exercise and wellbeing. Results: After adjustment for eating disorder symptoms and sporting level, compulsive exercise was associated with increased risk of clinically-significant anxiety, depression, and stress symptoms. Compulsive exercise was also associated with lower life satisfaction and self-esteem, and higher social physique anxiety. Notably, different dimensions of compulsive exercise had varying relationships with outcomes, and avoidance and rule-driven behaviour and lack of exercise enjoyment were associated with poorer mental health and wellbeing. Conclusions: Results suggest that compulsive exercise is uniquely associated with a range of psychosocial and mental health outcomes. Results support the need to improve identification and treatment of compulsive exercise in sport and exercise settings. Results highlight that mental health intervention is an important component of treatment, and treatments targeting symptoms related to avoidance and rule-driven behaviour, and anhedonia may be valuable treatment components for those with compulsive exercise. © 2023 The Author(s)
- Authors: Cosh, Suzanne , McNeil, Dominic , Tully, Phillip
- Date: 2023
- Type: Text , Journal article
- Relation: Journal of Science and Medicine in Sport Vol. 26, no. 7 (2023), p. 338-344
- Full Text:
- Reviewed:
- Description: Objectives: Better understanding of compulsive exercise is needed in sports medicine. Whilst compulsive exercise may impact mental health, the limited research exploring the relationship between compulsive exercise and psychosocial outcomes is equivocal. The majority of studies have examined eating disorder populations where the eating disorder pathology might account for distress. This study explores relationships between compulsive exercise and mental health. Design: Cross-sectional observational study. Methods: Australian recreational exercisers and athletes (N = 1157; Mage 36.4, standard deviation = 12.9, 77 % female) recruited through sporting organisations, clubs, and gyms, completed measures of compulsive exercise, depression, anxiety, stress, life satisfaction, social physique anxiety, and self-esteem. Regression analyses examined relationships between dimensions of compulsive exercise and wellbeing. Results: After adjustment for eating disorder symptoms and sporting level, compulsive exercise was associated with increased risk of clinically-significant anxiety, depression, and stress symptoms. Compulsive exercise was also associated with lower life satisfaction and self-esteem, and higher social physique anxiety. Notably, different dimensions of compulsive exercise had varying relationships with outcomes, and avoidance and rule-driven behaviour and lack of exercise enjoyment were associated with poorer mental health and wellbeing. Conclusions: Results suggest that compulsive exercise is uniquely associated with a range of psychosocial and mental health outcomes. Results support the need to improve identification and treatment of compulsive exercise in sport and exercise settings. Results highlight that mental health intervention is an important component of treatment, and treatments targeting symptoms related to avoidance and rule-driven behaviour, and anhedonia may be valuable treatment components for those with compulsive exercise. © 2023 The Author(s)
Concussion assessment and management — what do community-level cricket participants know?
- Kodikara, Dulan, Plumb, Mandy, Twomey, Dara
- Authors: Kodikara, Dulan , Plumb, Mandy , Twomey, Dara
- Date: 2023
- Type: Text , Journal article
- Relation: Journal of Science and Medicine in Sport Vol. 26, no. 9 (2023), p. 448-453
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- Description: Objectives: To explore Australian cricket participants' knowledge of concussion assessment and management, and awareness of current concussion guidelines. Design: Cross-sectional survey. Methods: Novel and validated surveys were disseminated online, among over 16 year Australian cricket players and officials at the end of the 2018/19 cricket season. Data were collected on knowledge and awareness of concussion and analysed using descriptive statistics and crosstabulations. Further comparisons were made for the players between injured and non-injured, and helmet wearers and non-helmet wearers using Fisher's exact statistical test. Results: Both players (n = 224, 93 %) and officials (n = 36, 100 %) demonstrated strong knowledge of the importance of immediately evaluating suspected concussions. In comparison with players without helmets (n = 11), those using helmets (n = 135) considered replacing their helmets after a concussion to be vital to concussion assessment (p = 0.02). Overall, 80–97 % of players and 81–97 % of officials understood the importance of many factors regarding concussion management. When concussion management knowledge was compared by injury status, injured players (n = 17, 94 %) believed someone with a concussion should be hospitalised immediately, in contrast to non-injured players (n = 154, 69 %) (p = 0.04). Players (63 %) were less aware of concussion guidelines than officials (81 %). Conclusions: Overall, the knowledge of concussion assessment and management was satisfactory. However, there were discrepancies among players on some aspects of awareness of concussion guidelines. Increasing players' familiarity and experience in using the concussion guidelines is warranted. Targeted campaigns are needed to further improve concussion recognition and treatment at community-level cricket, so all participants play a role in making cricket a safe sport. © 2023
- Authors: Kodikara, Dulan , Plumb, Mandy , Twomey, Dara
- Date: 2023
- Type: Text , Journal article
- Relation: Journal of Science and Medicine in Sport Vol. 26, no. 9 (2023), p. 448-453
- Full Text:
- Reviewed:
- Description: Objectives: To explore Australian cricket participants' knowledge of concussion assessment and management, and awareness of current concussion guidelines. Design: Cross-sectional survey. Methods: Novel and validated surveys were disseminated online, among over 16 year Australian cricket players and officials at the end of the 2018/19 cricket season. Data were collected on knowledge and awareness of concussion and analysed using descriptive statistics and crosstabulations. Further comparisons were made for the players between injured and non-injured, and helmet wearers and non-helmet wearers using Fisher's exact statistical test. Results: Both players (n = 224, 93 %) and officials (n = 36, 100 %) demonstrated strong knowledge of the importance of immediately evaluating suspected concussions. In comparison with players without helmets (n = 11), those using helmets (n = 135) considered replacing their helmets after a concussion to be vital to concussion assessment (p = 0.02). Overall, 80–97 % of players and 81–97 % of officials understood the importance of many factors regarding concussion management. When concussion management knowledge was compared by injury status, injured players (n = 17, 94 %) believed someone with a concussion should be hospitalised immediately, in contrast to non-injured players (n = 154, 69 %) (p = 0.04). Players (63 %) were less aware of concussion guidelines than officials (81 %). Conclusions: Overall, the knowledge of concussion assessment and management was satisfactory. However, there were discrepancies among players on some aspects of awareness of concussion guidelines. Increasing players' familiarity and experience in using the concussion guidelines is warranted. Targeted campaigns are needed to further improve concussion recognition and treatment at community-level cricket, so all participants play a role in making cricket a safe sport. © 2023
Coping strategies to overcome psychological distress and fear during COVID-19 pandemic in Kuwait
- Elaidy, Asmaa, Hammoud, Majeda, N. Albatineh, Ahmed, Ridha, Fatma, Hammoud, Sabri, Elsadek, Hala, Rahman, Muhammad Aziz
- Authors: Elaidy, Asmaa , Hammoud, Majeda , N. Albatineh, Ahmed , Ridha, Fatma , Hammoud, Sabri , Elsadek, Hala , Rahman, Muhammad Aziz
- Date: 2023
- Type: Text , Journal article
- Relation: Middle East Current Psychiatry Vol. 30, no. 1 (2023), p.
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- Description: Background: The COVID-19 pandemic has detrimental effects on both physical and psychological well-being of community people worldwide. The purpose of this research was to determine coping strategies and the factors associated with psychological distress and fear among adults in Kuwait during the COVID-19 pandemic. Results: Participants with good-excellent mental health perception had significantly lower prevalence of reporting high psychological distress, while those identified as patients as used health services in the past 4 weeks had significantly higher prevalence of reporting high psychological distress. On the other hand, individuals born in the same country of residence, whose financial situation was impacted by COVID-19 had significantly lower prevalence of reporting high levels of fear from COVID-19. Those with an income source, with co-morbidities, tested negative to COVID-19, being frontline or essential worker, reported medium to high psychological distress and had significantly higher prevalence of high levels of fear of COVID-19. Conclusions: Mental health services should be provided in addition to the existing services in primary healthcare settings, so that the impact of ongoing pandemic on psychological wellbeing of people in Kuwait can be addressed. © 2023, The Author(s).
- Authors: Elaidy, Asmaa , Hammoud, Majeda , N. Albatineh, Ahmed , Ridha, Fatma , Hammoud, Sabri , Elsadek, Hala , Rahman, Muhammad Aziz
- Date: 2023
- Type: Text , Journal article
- Relation: Middle East Current Psychiatry Vol. 30, no. 1 (2023), p.
- Full Text:
- Reviewed:
- Description: Background: The COVID-19 pandemic has detrimental effects on both physical and psychological well-being of community people worldwide. The purpose of this research was to determine coping strategies and the factors associated with psychological distress and fear among adults in Kuwait during the COVID-19 pandemic. Results: Participants with good-excellent mental health perception had significantly lower prevalence of reporting high psychological distress, while those identified as patients as used health services in the past 4 weeks had significantly higher prevalence of reporting high psychological distress. On the other hand, individuals born in the same country of residence, whose financial situation was impacted by COVID-19 had significantly lower prevalence of reporting high levels of fear from COVID-19. Those with an income source, with co-morbidities, tested negative to COVID-19, being frontline or essential worker, reported medium to high psychological distress and had significantly higher prevalence of high levels of fear of COVID-19. Conclusions: Mental health services should be provided in addition to the existing services in primary healthcare settings, so that the impact of ongoing pandemic on psychological wellbeing of people in Kuwait can be addressed. © 2023, The Author(s).
Countermovement jump variables not tensiomyography can distinguish between sprint and endurance focused track cyclists
- Lewis, Mitchell, Young, Warren, Knapstein, Luke, Lavender, Andrew, Talpey, Scott
- Authors: Lewis, Mitchell , Young, Warren , Knapstein, Luke , Lavender, Andrew , Talpey, Scott
- Date: 2022
- Type: Text , Journal article
- Relation: Biology of Sport Vol. 39, no. 1 (2022), p. 67-72
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- Description: This study investigated the reliability and discriminative ability of tensiomyography and countermovement jump variables as measures of a muscles contractile properties in a cohort of elite endurance and sprint track cyclists. Tensiomyography was performed on the vastus lateralis (VL) and rectus femoris (RF) muscles in sprint track cyclists (N = 8) and endurance track cyclists (N = 8). Additionally, the participants completed a countermovement jump on a force plate. Tensiomyography measurements obtained from the RF displayed greater reliability (ICC = 0.879–0.997) than VL (ICC = 0.746–0.970). Radial muscle belly displacement (Dm), contraction time (Tc) and delay time (Td) demonstrated the most reliable TMG measurements. Only two variables displayed acceptable coefficient of variation (RF Td = 8.89, VL Td = 6.88), other variables presented as unacceptable. The TMG variables were unable to discriminate between endurance and sprint track cyclists whilst the CMJ variables could. Due to the high variability in measurements and its inability to distinguish between sprint and endurance based track cyclists TMG should be used cautiously in this athlete population and if available the CMJ is a more appropriate assessment of leg muscle function. © 2022 Institute of Sport. All rights reserved.
- Authors: Lewis, Mitchell , Young, Warren , Knapstein, Luke , Lavender, Andrew , Talpey, Scott
- Date: 2022
- Type: Text , Journal article
- Relation: Biology of Sport Vol. 39, no. 1 (2022), p. 67-72
- Full Text:
- Reviewed:
- Description: This study investigated the reliability and discriminative ability of tensiomyography and countermovement jump variables as measures of a muscles contractile properties in a cohort of elite endurance and sprint track cyclists. Tensiomyography was performed on the vastus lateralis (VL) and rectus femoris (RF) muscles in sprint track cyclists (N = 8) and endurance track cyclists (N = 8). Additionally, the participants completed a countermovement jump on a force plate. Tensiomyography measurements obtained from the RF displayed greater reliability (ICC = 0.879–0.997) than VL (ICC = 0.746–0.970). Radial muscle belly displacement (Dm), contraction time (Tc) and delay time (Td) demonstrated the most reliable TMG measurements. Only two variables displayed acceptable coefficient of variation (RF Td = 8.89, VL Td = 6.88), other variables presented as unacceptable. The TMG variables were unable to discriminate between endurance and sprint track cyclists whilst the CMJ variables could. Due to the high variability in measurements and its inability to distinguish between sprint and endurance based track cyclists TMG should be used cautiously in this athlete population and if available the CMJ is a more appropriate assessment of leg muscle function. © 2022 Institute of Sport. All rights reserved.
Cross-sectional study of soil-transmitted helminthiases in black belt region of Alabama, USA
- Poole, Claudette, Barker, Troy, Bradbury, Richard, Capone, Drew, Chatham, Amy, Handali, Sukwan, Rodriguez, Eduardo, Qvarnstrom, Yvonne, Brown, Joe
- Authors: Poole, Claudette , Barker, Troy , Bradbury, Richard , Capone, Drew , Chatham, Amy , Handali, Sukwan , Rodriguez, Eduardo , Qvarnstrom, Yvonne , Brown, Joe
- Date: 2023
- Type: Text , Journal article
- Relation: Emerging Infectious Diseases Vol. 29, no. 12 (2023), p. 2461-2470
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- Description: We conducted a cross-sectional study to determine the prevalence of soil-transmitted helminthiases (STH) in areas of rural Alabama, USA, that have sanitation deficits. We enrolled 777 children; 704 submitted stool specimens and 227 a dried blood spot sample. We microscopically examined stool specimens from all 704 children by using Mini-FLOTAC for helminth eggs. We tested a subset by using molecular techniques: real-time PCR analysis for 5 STH species, TaqMan Array Cards for enteric helminths, and digital PCR for Necator americanus hookworm. We analyzed dried blood spots for Strongyloides stercoralis and Toxocara spp. roundworms by using serologic testing. Despite 12% of our cohort reporting living in homes that directly discharge untreated domestic wastewater, stool testing for STH was negative; however, 5% of dried blood spots were positive for Toxocara spp. roundworms. Survey data suggests substantial numbers of children in this region may be exposed to raw sewage, which is itself a major public health concern. © 2023 Centers for Disease Control and Prevention (CDC). All rights reserved.
- Authors: Poole, Claudette , Barker, Troy , Bradbury, Richard , Capone, Drew , Chatham, Amy , Handali, Sukwan , Rodriguez, Eduardo , Qvarnstrom, Yvonne , Brown, Joe
- Date: 2023
- Type: Text , Journal article
- Relation: Emerging Infectious Diseases Vol. 29, no. 12 (2023), p. 2461-2470
- Full Text:
- Reviewed:
- Description: We conducted a cross-sectional study to determine the prevalence of soil-transmitted helminthiases (STH) in areas of rural Alabama, USA, that have sanitation deficits. We enrolled 777 children; 704 submitted stool specimens and 227 a dried blood spot sample. We microscopically examined stool specimens from all 704 children by using Mini-FLOTAC for helminth eggs. We tested a subset by using molecular techniques: real-time PCR analysis for 5 STH species, TaqMan Array Cards for enteric helminths, and digital PCR for Necator americanus hookworm. We analyzed dried blood spots for Strongyloides stercoralis and Toxocara spp. roundworms by using serologic testing. Despite 12% of our cohort reporting living in homes that directly discharge untreated domestic wastewater, stool testing for STH was negative; however, 5% of dried blood spots were positive for Toxocara spp. roundworms. Survey data suggests substantial numbers of children in this region may be exposed to raw sewage, which is itself a major public health concern. © 2023 Centers for Disease Control and Prevention (CDC). All rights reserved.
Deficiency of MicroRNA-181a results in transcriptome-wide cell-specific changes in the kidney and increases blood pressure
- Paterson, Madeleine, Jackson, Kristy, Dona, Malathi, Farrugia, Gabriella, Visniauskas, Bruna, Watson, Anna, Johnson, Chad, Prieto, Minolfa, Evans, Roger, Charchar, Fadi, Pinto, Alexander, Marques, Francine, Head, Geoffrey
- Authors: Paterson, Madeleine , Jackson, Kristy , Dona, Malathi , Farrugia, Gabriella , Visniauskas, Bruna , Watson, Anna , Johnson, Chad , Prieto, Minolfa , Evans, Roger , Charchar, Fadi , Pinto, Alexander , Marques, Francine , Head, Geoffrey
- Date: 2021
- Type: Text , Journal article
- Relation: Hypertension Vol. 78, no. 5 (Nov 2021), p. 1322-1334
- Full Text:
- Reviewed:
- Description: MicroRNA miR-181a is downregulated in the kidneys of hypertensive patients and hypertensive mice. In vitro, miR-181a is a posttranslational inhibitor of renin expression, but pleiotropic mechanisms by which miR-181a may influence blood pressure (BP) are unknown. Here, we determined whether deletion of miR-181a/b-1 in vivo changes BP and the molecular mechanisms involved at the single-cell level. We developed a KO (knockout) mouse model lacking miR-181a/b-1 genes using CRISPR/Cas9 technology. Radiotelemetry probes were implanted in 12-week-old C57BL/6J WT (wild type) and miR-181a/b-1 KO mice. Systolic and diastolic BP were 4- to 5-mm Hg higher in KO compared with WT mice over 24 hours (P<0.01). Compared with WT mice, renal renin was higher in the juxtaglomerular cells of KO mice. BP was similar in WT mice on a high- (3.1%) versus low- (0.3%) sodium diet (+0.4 +/- 0.8 mm Hg), but KO mice showed salt sensitivity (+3.3 +/- 0.8 mm Hg; P<0.001). Since microRNAs can target several mRNAs simultaneously, we performed single-nuclei RNA sequencing in 6699 renal cells. We identified 12 distinct types of renal cells, all of which had genes that were dysregulated. This included genes involved in renal fibrosis and inflammation such as Stat4, Col4a1, Cd81, Flt3l, Cxcl16, and Smad4. We observed upregulation of pathways related to the immune system, inflammatory response, reactive oxygen species, and nerve development, consistent with higher tyrosine hydroxylase in the kidney. In conclusion, downregulation of the miR-181a gene led to increased BP and salt sensitivity in mice. This is likely due to an increase in renin expression in juxtaglomerular cells, as well as microRNA-driven pleiotropic effects impacting renal pathways associated with hypertension.
- Authors: Paterson, Madeleine , Jackson, Kristy , Dona, Malathi , Farrugia, Gabriella , Visniauskas, Bruna , Watson, Anna , Johnson, Chad , Prieto, Minolfa , Evans, Roger , Charchar, Fadi , Pinto, Alexander , Marques, Francine , Head, Geoffrey
- Date: 2021
- Type: Text , Journal article
- Relation: Hypertension Vol. 78, no. 5 (Nov 2021), p. 1322-1334
- Full Text:
- Reviewed:
- Description: MicroRNA miR-181a is downregulated in the kidneys of hypertensive patients and hypertensive mice. In vitro, miR-181a is a posttranslational inhibitor of renin expression, but pleiotropic mechanisms by which miR-181a may influence blood pressure (BP) are unknown. Here, we determined whether deletion of miR-181a/b-1 in vivo changes BP and the molecular mechanisms involved at the single-cell level. We developed a KO (knockout) mouse model lacking miR-181a/b-1 genes using CRISPR/Cas9 technology. Radiotelemetry probes were implanted in 12-week-old C57BL/6J WT (wild type) and miR-181a/b-1 KO mice. Systolic and diastolic BP were 4- to 5-mm Hg higher in KO compared with WT mice over 24 hours (P<0.01). Compared with WT mice, renal renin was higher in the juxtaglomerular cells of KO mice. BP was similar in WT mice on a high- (3.1%) versus low- (0.3%) sodium diet (+0.4 +/- 0.8 mm Hg), but KO mice showed salt sensitivity (+3.3 +/- 0.8 mm Hg; P<0.001). Since microRNAs can target several mRNAs simultaneously, we performed single-nuclei RNA sequencing in 6699 renal cells. We identified 12 distinct types of renal cells, all of which had genes that were dysregulated. This included genes involved in renal fibrosis and inflammation such as Stat4, Col4a1, Cd81, Flt3l, Cxcl16, and Smad4. We observed upregulation of pathways related to the immune system, inflammatory response, reactive oxygen species, and nerve development, consistent with higher tyrosine hydroxylase in the kidney. In conclusion, downregulation of the miR-181a gene led to increased BP and salt sensitivity in mice. This is likely due to an increase in renin expression in juxtaglomerular cells, as well as microRNA-driven pleiotropic effects impacting renal pathways associated with hypertension.
Diabetes mortality and trends before 25 years of age : an analysis of the global burden of disease study 2019
- Cousin, Ewerton, Duncan, Bruce, Stein, Caroline, Ong, Kanyin, Vos, Theo, Abbafati, Cristiana, Abbasi-Kangevari, Mohsen, Abdelmasseh, Michael, Abdoli, Amir, Abd-Rabu, Rami, Abolhassani, Hassan, Abu-Gharbieh, Eman, Accrombessi, Manfred, Adnani, Qorinah, Afzal, Muhammad, Agarwal, Gina, Agrawaal, Krishna, Agudelo-Botero, Marcela, Ahinkorah, Bright, Ahmad, Sajjad, Ahmad, Tauseef, Ahmadi, Keivan, Ahmadi, Sepideh, Ahmadi, Ali, Ahmed, Ali, Ahmed Salih, Yusra, Akande-Sholabi, Wuraola, Akram, Tayyaba, Al Hamad, Hanadi, Al-Aly, Ziyad, Rahman, Muhammad Aziz
- Authors: Cousin, Ewerton , Duncan, Bruce , Stein, Caroline , Ong, Kanyin , Vos, Theo , Abbafati, Cristiana , Abbasi-Kangevari, Mohsen , Abdelmasseh, Michael , Abdoli, Amir , Abd-Rabu, Rami , Abolhassani, Hassan , Abu-Gharbieh, Eman , Accrombessi, Manfred , Adnani, Qorinah , Afzal, Muhammad , Agarwal, Gina , Agrawaal, Krishna , Agudelo-Botero, Marcela , Ahinkorah, Bright , Ahmad, Sajjad , Ahmad, Tauseef , Ahmadi, Keivan , Ahmadi, Sepideh , Ahmadi, Ali , Ahmed, Ali , Ahmed Salih, Yusra , Akande-Sholabi, Wuraola , Akram, Tayyaba , Al Hamad, Hanadi , Al-Aly, Ziyad , Rahman, Muhammad Aziz
- Date: 2022
- Type: Text , Journal article
- Relation: The Lancet Diabetes and Endocrinology Vol. 10, no. 3 (2022), p. 177-192
- Full Text:
- Reviewed:
- Description: Background: Diabetes, particularly type 1 diabetes, at younger ages can be a largely preventable cause of death with the correct health care and services. We aimed to evaluate diabetes mortality and trends at ages younger than 25 years globally using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. Methods: We used estimates of GBD 2019 to calculate international diabetes mortality at ages younger than 25 years in 1990 and 2019. Data sources for causes of death were obtained from vital registration systems, verbal autopsies, and other surveillance systems for 1990–2019. We estimated death rates for each location using the GBD Cause of Death Ensemble model. We analysed the association of age-standardised death rates per 100 000 population with the Socio-demographic Index (SDI) and a measure of universal health coverage (UHC) and described the variability within SDI quintiles. We present estimates with their 95% uncertainty intervals. Findings: In 2019, 16 300 (95% uncertainty interval 14 200 to 18 900) global deaths due to diabetes (type 1 and 2 combined) occurred in people younger than 25 years and 73·7% (68·3 to 77·4) were classified as due to type 1 diabetes. The age-standardised death rate was 0·50 (0·44 to 0·58) per 100 000 population, and 15 900 (97·5%) of these deaths occurred in low to high-middle SDI countries. The rate was 0·13 (0·12 to 0·14) per 100 000 population in the high SDI quintile, 0·60 (0·51 to 0·70) per 100 000 population in the low-middle SDI quintile, and 0·71 (0·60 to 0·86) per 100 000 population in the low SDI quintile. Within SDI quintiles, we observed large variability in rates across countries, in part explained by the extent of UHC (r2=0·62). From 1990 to 2019, age-standardised death rates decreased globally by 17·0%. **Please note that there are multiple authors for this article therefore only the name of the first 30 including Federation University Australia affiliate “Muhammad Aziz Rahman" is provided in this record**
- Description: Background: Diabetes, particularly type 1 diabetes, at younger ages can be a largely preventable cause of death with the correct health care and services. We aimed to evaluate diabetes mortality and trends at ages younger than 25 years globally using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. Methods: We used estimates of GBD 2019 to calculate international diabetes mortality at ages younger than 25 years in 1990 and 2019. Data sources for causes of death were obtained from vital registration systems, verbal autopsies, and other surveillance systems for 1990–2019. We estimated death rates for each location using the GBD Cause of Death Ensemble model. We analysed the association of age-standardised death rates per 100 000 population with the Socio-demographic Index (SDI) and a measure of universal health coverage (UHC) and described the variability within SDI quintiles. We present estimates with their 95% uncertainty intervals. Findings: In 2019, 16 300 (95% uncertainty interval 14 200 to 18 900) global deaths due to diabetes (type 1 and 2 combined) occurred in people younger than 25 years and 73·7% (68·3 to 77·4) were classified as due to type 1 diabetes. The age-standardised death rate was 0·50 (0·44 to 0·58) per 100 000 population, and 15 900 (97·5%) of these deaths occurred in low to high-middle SDI countries. The rate was 0·13 (0·12 to 0·14) per 100 000 population in the high SDI quintile, 0·60 (0·51 to 0·70) per 100 000 population in the low-middle SDI quintile, and 0·71 (0·60 to 0·86) per 100 000 population in the low SDI quintile. Within SDI quintiles, we observed large variability in rates across countries, in part explained by the extent of UHC (r2=0·62). From 1990 to 2019, age-standardised death rates decreased globally by 17·0% (
- Authors: Cousin, Ewerton , Duncan, Bruce , Stein, Caroline , Ong, Kanyin , Vos, Theo , Abbafati, Cristiana , Abbasi-Kangevari, Mohsen , Abdelmasseh, Michael , Abdoli, Amir , Abd-Rabu, Rami , Abolhassani, Hassan , Abu-Gharbieh, Eman , Accrombessi, Manfred , Adnani, Qorinah , Afzal, Muhammad , Agarwal, Gina , Agrawaal, Krishna , Agudelo-Botero, Marcela , Ahinkorah, Bright , Ahmad, Sajjad , Ahmad, Tauseef , Ahmadi, Keivan , Ahmadi, Sepideh , Ahmadi, Ali , Ahmed, Ali , Ahmed Salih, Yusra , Akande-Sholabi, Wuraola , Akram, Tayyaba , Al Hamad, Hanadi , Al-Aly, Ziyad , Rahman, Muhammad Aziz
- Date: 2022
- Type: Text , Journal article
- Relation: The Lancet Diabetes and Endocrinology Vol. 10, no. 3 (2022), p. 177-192
- Full Text:
- Reviewed:
- Description: Background: Diabetes, particularly type 1 diabetes, at younger ages can be a largely preventable cause of death with the correct health care and services. We aimed to evaluate diabetes mortality and trends at ages younger than 25 years globally using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. Methods: We used estimates of GBD 2019 to calculate international diabetes mortality at ages younger than 25 years in 1990 and 2019. Data sources for causes of death were obtained from vital registration systems, verbal autopsies, and other surveillance systems for 1990–2019. We estimated death rates for each location using the GBD Cause of Death Ensemble model. We analysed the association of age-standardised death rates per 100 000 population with the Socio-demographic Index (SDI) and a measure of universal health coverage (UHC) and described the variability within SDI quintiles. We present estimates with their 95% uncertainty intervals. Findings: In 2019, 16 300 (95% uncertainty interval 14 200 to 18 900) global deaths due to diabetes (type 1 and 2 combined) occurred in people younger than 25 years and 73·7% (68·3 to 77·4) were classified as due to type 1 diabetes. The age-standardised death rate was 0·50 (0·44 to 0·58) per 100 000 population, and 15 900 (97·5%) of these deaths occurred in low to high-middle SDI countries. The rate was 0·13 (0·12 to 0·14) per 100 000 population in the high SDI quintile, 0·60 (0·51 to 0·70) per 100 000 population in the low-middle SDI quintile, and 0·71 (0·60 to 0·86) per 100 000 population in the low SDI quintile. Within SDI quintiles, we observed large variability in rates across countries, in part explained by the extent of UHC (r2=0·62). From 1990 to 2019, age-standardised death rates decreased globally by 17·0%. **Please note that there are multiple authors for this article therefore only the name of the first 30 including Federation University Australia affiliate “Muhammad Aziz Rahman" is provided in this record**
- Description: Background: Diabetes, particularly type 1 diabetes, at younger ages can be a largely preventable cause of death with the correct health care and services. We aimed to evaluate diabetes mortality and trends at ages younger than 25 years globally using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. Methods: We used estimates of GBD 2019 to calculate international diabetes mortality at ages younger than 25 years in 1990 and 2019. Data sources for causes of death were obtained from vital registration systems, verbal autopsies, and other surveillance systems for 1990–2019. We estimated death rates for each location using the GBD Cause of Death Ensemble model. We analysed the association of age-standardised death rates per 100 000 population with the Socio-demographic Index (SDI) and a measure of universal health coverage (UHC) and described the variability within SDI quintiles. We present estimates with their 95% uncertainty intervals. Findings: In 2019, 16 300 (95% uncertainty interval 14 200 to 18 900) global deaths due to diabetes (type 1 and 2 combined) occurred in people younger than 25 years and 73·7% (68·3 to 77·4) were classified as due to type 1 diabetes. The age-standardised death rate was 0·50 (0·44 to 0·58) per 100 000 population, and 15 900 (97·5%) of these deaths occurred in low to high-middle SDI countries. The rate was 0·13 (0·12 to 0·14) per 100 000 population in the high SDI quintile, 0·60 (0·51 to 0·70) per 100 000 population in the low-middle SDI quintile, and 0·71 (0·60 to 0·86) per 100 000 population in the low SDI quintile. Within SDI quintiles, we observed large variability in rates across countries, in part explained by the extent of UHC (r2=0·62). From 1990 to 2019, age-standardised death rates decreased globally by 17·0% (
Dietary supplements in people with metastatic cancer who are experiencing malnutrition, cachexia, sarcopenia, and frailty : a scoping review
- Johal, Jolyn, Han, Chad, Joseph, Ria, Munn, Zachary, Agbejule, Oluwaseyifunmi, Crawford‐Williams, Fiona, Wallen, Matthew, Chan, Raymond, Hart, Nicolas
- Authors: Johal, Jolyn , Han, Chad , Joseph, Ria , Munn, Zachary , Agbejule, Oluwaseyifunmi , Crawford‐Williams, Fiona , Wallen, Matthew , Chan, Raymond , Hart, Nicolas
- Date: 2022
- Type: Text , Journal article , Review
- Relation: Nutrients Vol. 14, no. 13 (2022), p.
- Full Text:
- Reviewed:
- Description: Cancer‐associated malnutrition, or cachexia, stemming from cancer or its treatments, is particularly prevalent in metastatic cancers, and is often interrelated with sarcopenia and frailty. Evidence suggests that dietary supplements play a role in managing these conditions. As metastatic cancer cells are associated with notable genomic and phenotypic alterations, response to dietary supplements may differ between metastatic and non‐metastatic cancers. However, research in this area is lacking. This scoping review aims to identify the dietary supplements that have been studied in patients with metastatic cancers and malnutrition‐related conditions, along with their proposed effects, mechanisms, outcome measures, and tools used. A systematic search was conducted across databases, including MEDLINE, EMBASE, CINAHL, and clinical trial registries. Of the initial 6535 records screened, a total of 48 studies were included, covering a range of dietary supplements— vitamins, minerals, antioxidants, proteins, amino acids, fatty acids, fiber, and others. While the types of dietary supplements included varied across cancer types, omega‐3 and carnitine were investigated most often. Proposed relevant attributes of dietary supplements included their antioxidant, anti‐inflammatory, anti‐cancer, and immunomodulatory properties. Overall, there was a paucity of interventional studies, and more randomized controlled trials are warranted. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
- Authors: Johal, Jolyn , Han, Chad , Joseph, Ria , Munn, Zachary , Agbejule, Oluwaseyifunmi , Crawford‐Williams, Fiona , Wallen, Matthew , Chan, Raymond , Hart, Nicolas
- Date: 2022
- Type: Text , Journal article , Review
- Relation: Nutrients Vol. 14, no. 13 (2022), p.
- Full Text:
- Reviewed:
- Description: Cancer‐associated malnutrition, or cachexia, stemming from cancer or its treatments, is particularly prevalent in metastatic cancers, and is often interrelated with sarcopenia and frailty. Evidence suggests that dietary supplements play a role in managing these conditions. As metastatic cancer cells are associated with notable genomic and phenotypic alterations, response to dietary supplements may differ between metastatic and non‐metastatic cancers. However, research in this area is lacking. This scoping review aims to identify the dietary supplements that have been studied in patients with metastatic cancers and malnutrition‐related conditions, along with their proposed effects, mechanisms, outcome measures, and tools used. A systematic search was conducted across databases, including MEDLINE, EMBASE, CINAHL, and clinical trial registries. Of the initial 6535 records screened, a total of 48 studies were included, covering a range of dietary supplements— vitamins, minerals, antioxidants, proteins, amino acids, fatty acids, fiber, and others. While the types of dietary supplements included varied across cancer types, omega‐3 and carnitine were investigated most often. Proposed relevant attributes of dietary supplements included their antioxidant, anti‐inflammatory, anti‐cancer, and immunomodulatory properties. Overall, there was a paucity of interventional studies, and more randomized controlled trials are warranted. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
Differences between DSM-5-TR and ICD-11 revisions of attention deficit/hyperactivity disorder : a commentary on implications and opportunities
- Gomez, Rapson, Chen, Wai, Houghton, Stephen
- Authors: Gomez, Rapson , Chen, Wai , Houghton, Stephen
- Date: 2023
- Type: Text , Journal article
- Relation: World J Psychiatry Vol. 13, no. 5 (2023), p. 138-143
- Full Text:
- Reviewed:
- Description: Current ICD-11 descriptions for attention deficit hyperactivity disorder (ADHD) were recently published online, in the same year as the DSM-5-TR (text revised edition) was released. In this commentary, we compare and contrast the DSM-5/DSM-5-TR and ICD-11 diagnostic criteria, summarize important differences, and underscore their clinical and research implications. Overall, three major differences emerge: (1) The number of diagnostic criteria for inattention (IA), hyperactivity (HY) and impulsivity (IM) symptoms ( , DSM-5-TR has nine IA and nine HY/IM symptoms, whereas ICD-11 has 11 IA and 11 HY/IM sym-ptoms) (2) the clarity and standardization of diagnostic thresholds ( , the diagnostic thresholds for symptom count in IA and HY/IM domains are explicitly specified in DSM-5-TR, whereas in ICD-11 they are not) and (3) the partitioning of HY and IM symptoms into sub-dimensions ( , difference in partitioning HY and IM symptom domains relates to the differences between the current and previous editions of DSM and ICD, and this has important research implications). Currently, no ICD-11 based ADHD rating scales exist and while this absence represents an obstacle for respective research and clinical practice, it also presents opportunities for research development. This article highlights these challenges, possible remedies and novel research opportunities.
- Authors: Gomez, Rapson , Chen, Wai , Houghton, Stephen
- Date: 2023
- Type: Text , Journal article
- Relation: World J Psychiatry Vol. 13, no. 5 (2023), p. 138-143
- Full Text:
- Reviewed:
- Description: Current ICD-11 descriptions for attention deficit hyperactivity disorder (ADHD) were recently published online, in the same year as the DSM-5-TR (text revised edition) was released. In this commentary, we compare and contrast the DSM-5/DSM-5-TR and ICD-11 diagnostic criteria, summarize important differences, and underscore their clinical and research implications. Overall, three major differences emerge: (1) The number of diagnostic criteria for inattention (IA), hyperactivity (HY) and impulsivity (IM) symptoms ( , DSM-5-TR has nine IA and nine HY/IM symptoms, whereas ICD-11 has 11 IA and 11 HY/IM sym-ptoms) (2) the clarity and standardization of diagnostic thresholds ( , the diagnostic thresholds for symptom count in IA and HY/IM domains are explicitly specified in DSM-5-TR, whereas in ICD-11 they are not) and (3) the partitioning of HY and IM symptoms into sub-dimensions ( , difference in partitioning HY and IM symptom domains relates to the differences between the current and previous editions of DSM and ICD, and this has important research implications). Currently, no ICD-11 based ADHD rating scales exist and while this absence represents an obstacle for respective research and clinical practice, it also presents opportunities for research development. This article highlights these challenges, possible remedies and novel research opportunities.