An examination of physical exercise therapy on quality of life (QoL) and mortality in men diagnosed with Prostate Cancer (PCa)
- Authors: Khan, Nazib
- Date: 2023
- Type: Text , Thesis , PhD
- Full Text:
- Description: Prostate cancer (PCa) is the second most frequent malignancy in men worldwide, accounting for 27% of new cancer cases in men and responsible for 3.8% of worldwide male cancer deaths (2018). This risk is projected to double before 204, so it is surprising that there are no well- established modifiable risk factors for PCa diagnosis orr progression. Considering this, the following thesis consists of three original research studies that examined; (1) the moderating effect of physical activity and muscular strength on prostate cancer mortality; (2) the magnitude of effect from pooled therapeutic exercise studies to impact quality of life and adverse events in PCa patients following surgery; (3) the head-to-head comparative efficacy of individual exercise therapies to impact quality of life and adverse events following surgery. The sum of works presented in this thesis lead to the conclusion that 1) when PCa is the only lifetime cancer diagnosis, life expectancy is similar to lifetime cancer free counterparts whereas diagnosis of PCa with any other lifetime cancer is associated with a 30.2% lower life expectancy during 10-year follow-up. Physical activity has negligible effect on life-expectancy whereas handgrip strength accounts for ~4% of the difference in life-expectancy between PCa with any other lifetime cancer compared with controls; 2) Pooled evidence from randomised controlled trials (n=999 participants) identifies that perioperative exercise therapy (aerobic, resistance, pelvic floor, mind-body exercise, or mixed exercise (combined aerobic and resistance) has a positive impact on patient quality of life and adverse events in PCa patients undergoing surgery which is predominant in perceptions of symptom related QoL (SMD: 0.56, 111 95% CI’s [0.22-0.89]) more so than health related quality of life (HRQoL) (SMD: 0.02, 95% 112 CI’s [-0.16-0.20]; 3) Comparison of head-to-head efficacy of different therapeutic exercise interventions [Aerobic, resistance, pelvic floor, mind-body exercise or mixed exercise (combined aerobic and resistance)] identified pelvic floor muscle exercise to be the most favorable exercise therapy to maintain QoL in PCa patients undergoing surgery, partly due to the current lack of evidence to support other exercise therapies. These findings provide new knowledge to support the effective treatment of PCa patients.
- Description: Doctor of Philosophy
- Authors: Khan, Nazib
- Date: 2023
- Type: Text , Thesis , PhD
- Full Text:
- Description: Prostate cancer (PCa) is the second most frequent malignancy in men worldwide, accounting for 27% of new cancer cases in men and responsible for 3.8% of worldwide male cancer deaths (2018). This risk is projected to double before 204, so it is surprising that there are no well- established modifiable risk factors for PCa diagnosis orr progression. Considering this, the following thesis consists of three original research studies that examined; (1) the moderating effect of physical activity and muscular strength on prostate cancer mortality; (2) the magnitude of effect from pooled therapeutic exercise studies to impact quality of life and adverse events in PCa patients following surgery; (3) the head-to-head comparative efficacy of individual exercise therapies to impact quality of life and adverse events following surgery. The sum of works presented in this thesis lead to the conclusion that 1) when PCa is the only lifetime cancer diagnosis, life expectancy is similar to lifetime cancer free counterparts whereas diagnosis of PCa with any other lifetime cancer is associated with a 30.2% lower life expectancy during 10-year follow-up. Physical activity has negligible effect on life-expectancy whereas handgrip strength accounts for ~4% of the difference in life-expectancy between PCa with any other lifetime cancer compared with controls; 2) Pooled evidence from randomised controlled trials (n=999 participants) identifies that perioperative exercise therapy (aerobic, resistance, pelvic floor, mind-body exercise, or mixed exercise (combined aerobic and resistance) has a positive impact on patient quality of life and adverse events in PCa patients undergoing surgery which is predominant in perceptions of symptom related QoL (SMD: 0.56, 111 95% CI’s [0.22-0.89]) more so than health related quality of life (HRQoL) (SMD: 0.02, 95% 112 CI’s [-0.16-0.20]; 3) Comparison of head-to-head efficacy of different therapeutic exercise interventions [Aerobic, resistance, pelvic floor, mind-body exercise or mixed exercise (combined aerobic and resistance)] identified pelvic floor muscle exercise to be the most favorable exercise therapy to maintain QoL in PCa patients undergoing surgery, partly due to the current lack of evidence to support other exercise therapies. These findings provide new knowledge to support the effective treatment of PCa patients.
- Description: Doctor of Philosophy
Identifying complementary and alternative medicine recommendations for anxiety treatment and care : a systematic review and critical assessment of comprehensive clinical practice guidelines
- Zhao, Fei-Yi, Kennedy, Gerard, Xu, Peijie, Conduit, Russell, Wang, Yan-Mei, Zhang, Wen-Jing, Wang, Hui-Ru, Yue, Li-Ping, Huang, Yu-Ling, Wang, Yin, Xu, Yan, Fu, Qiang-Qiang, Zheng, Zhen
- Authors: Zhao, Fei-Yi , Kennedy, Gerard , Xu, Peijie , Conduit, Russell , Wang, Yan-Mei , Zhang, Wen-Jing , Wang, Hui-Ru , Yue, Li-Ping , Huang, Yu-Ling , Wang, Yin , Xu, Yan , Fu, Qiang-Qiang , Zheng, Zhen
- Date: 2023
- Type: Text , Journal article , Review
- Relation: Frontiers in Psychiatry Vol. 14, no. (2023), p.
- Full Text:
- Reviewed:
- Description: Background: Clinical practice guidelines (CPGs) are used to guide decision-making, especially regarding complementary and alternative medicine (CAM) therapies that are unfamiliar to orthodox healthcare providers. This systematic review aimed to critically review and summarise CAM recommendations associated with anxiety management included in the existing CPGs. Methods: Seven databases, websites of six international guidelines developing institutions, and the National Centre for Complementary and Integrative Health website were systematically searched. Their reporting and methodological quality were evaluated using the Reporting Items for practice Guidelines in Healthcare checklist and the Appraisal of Guidelines for Research and Evaluation (2nd version) instrument, respectively. Results: Ten CPGs were included, with reporting rates between 51.4 and 88.6%. Seven of these were of moderate to high methodological quality. Seventeen CAM modalities were implicated, involving phytotherapeutics, mind–body practice, art therapy, and homeopathy. Applied relaxation was included in 70% CPGs, which varied in degree of support for its use in the treatment of generalised anxiety disorder. There were few recommendations for other therapies/products. Light therapy was not recommended for use in generalised anxiety disorder, and St John’s wort and mindfulness were not recommended for use in social anxiety disorder in individual guidelines. Recommendations for the applicability of other therapies/products for treating a specific anxiety disorder were commonly graded as “unclear, unambiguous, or uncertain”. No CAM recommendations were provided for separation anxiety disorder, specific phobia or selective mutism. Conclusion: Available guidelines are limited in providing logically explained graded CAM recommendations for anxiety treatment and care. A lack of high-quality evidence and multidisciplinary consultation during the guideline development are two major reasons. High quality and reliable clinical evidence and the engagement of a range of interdisciplinary stakeholders are needed for future CPG development and updating. Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022373694, identifier CRD42022373694. Copyright © 2023 Zhao, Kennedy, Xu, Conduit, Wang, Zhang, Wang, Yue, Huang, Wang, Xu, Fu and Zheng.
- Authors: Zhao, Fei-Yi , Kennedy, Gerard , Xu, Peijie , Conduit, Russell , Wang, Yan-Mei , Zhang, Wen-Jing , Wang, Hui-Ru , Yue, Li-Ping , Huang, Yu-Ling , Wang, Yin , Xu, Yan , Fu, Qiang-Qiang , Zheng, Zhen
- Date: 2023
- Type: Text , Journal article , Review
- Relation: Frontiers in Psychiatry Vol. 14, no. (2023), p.
- Full Text:
- Reviewed:
- Description: Background: Clinical practice guidelines (CPGs) are used to guide decision-making, especially regarding complementary and alternative medicine (CAM) therapies that are unfamiliar to orthodox healthcare providers. This systematic review aimed to critically review and summarise CAM recommendations associated with anxiety management included in the existing CPGs. Methods: Seven databases, websites of six international guidelines developing institutions, and the National Centre for Complementary and Integrative Health website were systematically searched. Their reporting and methodological quality were evaluated using the Reporting Items for practice Guidelines in Healthcare checklist and the Appraisal of Guidelines for Research and Evaluation (2nd version) instrument, respectively. Results: Ten CPGs were included, with reporting rates between 51.4 and 88.6%. Seven of these were of moderate to high methodological quality. Seventeen CAM modalities were implicated, involving phytotherapeutics, mind–body practice, art therapy, and homeopathy. Applied relaxation was included in 70% CPGs, which varied in degree of support for its use in the treatment of generalised anxiety disorder. There were few recommendations for other therapies/products. Light therapy was not recommended for use in generalised anxiety disorder, and St John’s wort and mindfulness were not recommended for use in social anxiety disorder in individual guidelines. Recommendations for the applicability of other therapies/products for treating a specific anxiety disorder were commonly graded as “unclear, unambiguous, or uncertain”. No CAM recommendations were provided for separation anxiety disorder, specific phobia or selective mutism. Conclusion: Available guidelines are limited in providing logically explained graded CAM recommendations for anxiety treatment and care. A lack of high-quality evidence and multidisciplinary consultation during the guideline development are two major reasons. High quality and reliable clinical evidence and the engagement of a range of interdisciplinary stakeholders are needed for future CPG development and updating. Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022373694, identifier CRD42022373694. Copyright © 2023 Zhao, Kennedy, Xu, Conduit, Wang, Zhang, Wang, Yue, Huang, Wang, Xu, Fu and Zheng.
Identifying complementary and alternative medicine recommendations for insomnia treatment and care : a systematic review and critical assessment of comprehensive clinical practice guidelines
- Zhao, Fei-Yi. Y., Xu, Peijie, Kennedy, Gerard, Conduit, Russell, Zhang, Wen-Jing, Wang, Yan-Mei, Fu, Qiang-Qiang, Zheng, Zhen
- Authors: Zhao, Fei-Yi. Y. , Xu, Peijie , Kennedy, Gerard , Conduit, Russell , Zhang, Wen-Jing , Wang, Yan-Mei , Fu, Qiang-Qiang , Zheng, Zhen
- Date: 2023
- Type: Text , Journal article , Review
- Relation: Frontiers in Public Health Vol. 11, no. (2023), p.
- Full Text:
- Reviewed:
- Description: Background: There is a need for evidence-informed guidance on the use of complementary and alternative medicine (CAM) for insomnia because of its widespread utilization and a lack of guidance on the balance of benefits and harms. This systematic review aimed to identify and summarize the CAM recommendations associated with insomnia treatment and care from existing comprehensive clinical practice guidelines (CPGs). The quality of the eligible guidelines was appraised to assess the credibility of these recommendations. Methods: Formally published CPGs incorporating CAM recommendations for insomnia management were searched for in seven databases from their inception to January 2023. The NCCIH website and six websites of international guideline developing institutions were also retrieved. The methodological and reporting quality of each included guideline was appraised using the AGREE II instrument and RIGHT statement, respectively. Results: Seventeen eligible GCPs were included, and 14 were judged to be of moderate to high methodological and reporting quality. The reporting rate of eligible CPGs ranged from 42.9 to 97.1%. Twenty-two CAM modalities were implicated, involving nutritional or natural products, physical CAM, psychological CAM, homeopathy, aromatherapy, and mindful movements. Recommendations for these modalities were mostly unclear, unambiguous, uncertain, or conflicting. Logically explained graded recommendations supporting the CAM use in the treatment and/or care of insomnia were scarce, with bibliotherapy, Tai Chi, Yoga, and auriculotherapy positively recommended based on little and weak evidence. The only consensus was that four phytotherapeutics including valerian, chamomile, kava, and aromatherapy were not recommended for insomnia management because of risk profile and/or limited benefits. Conclusions: Existing guidelines are generally limited in providing clear, evidence-informed recommendations for the use of CAM therapies for insomnia management due to a lack of high-quality evidence and multidisciplinary consultation in CPG development. More well-designed studies to provide reliable clinical evidence are therefore urgently needed. Allowing the engagement of a range of interdisciplinary stakeholders in future updates of CPGs is also warranted. Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=369155, identifier: CRD42022369155. Copyright © 2023 Zhao, Xu, Kennedy, Conduit, Zhang, Wang, Fu and Zheng.
- Authors: Zhao, Fei-Yi. Y. , Xu, Peijie , Kennedy, Gerard , Conduit, Russell , Zhang, Wen-Jing , Wang, Yan-Mei , Fu, Qiang-Qiang , Zheng, Zhen
- Date: 2023
- Type: Text , Journal article , Review
- Relation: Frontiers in Public Health Vol. 11, no. (2023), p.
- Full Text:
- Reviewed:
- Description: Background: There is a need for evidence-informed guidance on the use of complementary and alternative medicine (CAM) for insomnia because of its widespread utilization and a lack of guidance on the balance of benefits and harms. This systematic review aimed to identify and summarize the CAM recommendations associated with insomnia treatment and care from existing comprehensive clinical practice guidelines (CPGs). The quality of the eligible guidelines was appraised to assess the credibility of these recommendations. Methods: Formally published CPGs incorporating CAM recommendations for insomnia management were searched for in seven databases from their inception to January 2023. The NCCIH website and six websites of international guideline developing institutions were also retrieved. The methodological and reporting quality of each included guideline was appraised using the AGREE II instrument and RIGHT statement, respectively. Results: Seventeen eligible GCPs were included, and 14 were judged to be of moderate to high methodological and reporting quality. The reporting rate of eligible CPGs ranged from 42.9 to 97.1%. Twenty-two CAM modalities were implicated, involving nutritional or natural products, physical CAM, psychological CAM, homeopathy, aromatherapy, and mindful movements. Recommendations for these modalities were mostly unclear, unambiguous, uncertain, or conflicting. Logically explained graded recommendations supporting the CAM use in the treatment and/or care of insomnia were scarce, with bibliotherapy, Tai Chi, Yoga, and auriculotherapy positively recommended based on little and weak evidence. The only consensus was that four phytotherapeutics including valerian, chamomile, kava, and aromatherapy were not recommended for insomnia management because of risk profile and/or limited benefits. Conclusions: Existing guidelines are generally limited in providing clear, evidence-informed recommendations for the use of CAM therapies for insomnia management due to a lack of high-quality evidence and multidisciplinary consultation in CPG development. More well-designed studies to provide reliable clinical evidence are therefore urgently needed. Allowing the engagement of a range of interdisciplinary stakeholders in future updates of CPGs is also warranted. Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=369155, identifier: CRD42022369155. Copyright © 2023 Zhao, Xu, Kennedy, Conduit, Zhang, Wang, Fu and Zheng.
- Lindsay, Riki, Larkin, Paul, Kittel, Aden, Spittle, Michael
- Authors: Lindsay, Riki , Larkin, Paul , Kittel, Aden , Spittle, Michael
- Date: 2023
- Type: Text , Journal article
- Relation: Physical education and sport pedagogy Vol. 28, no. 4 (2023), p. 444-465
- Full Text: false
- Reviewed:
- Description: Physical practice is the cornerstone of acquiring and developing movement skills in physical education and sport. However, research has suggested that psychological tools, such as mental imagery (MI), could effectively supplement a learner's physical practice schedule. MI is the mental simulation of a movement or situation in the absence of an overt physical output. Previous reviews have established the efficacy of MI for improving motor skills in sport. Further investigation, however, will help strengthen previous findings by focusing exclusively on studies that apply MI programs for the development of sport-specific motor skills. The purpose of this paper is to examine the overall effectiveness of MI programs for developing sport-specific motor skills and investigate program principles that may moderate the efficacy of MI programs, such as practice type, skill level, skill complexity, performance measures, duration, practice setting, and session frequency. By examining key program variables for MI, this review seeks to provide practical recommendations for physical educators and sports coaches on how they might effectively design and deliver a MI program to develop sport-specific motor skills. The review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. To provide practical recommendations for physical educators and sports coaches for effective MI programs, the following moderator variables were examined using subgroup analysis: (1) skill complexity, (2) skill level, (3) program duration, (4) session frequency, (5) MI practice type, and (6) practice context. The PEDro scale was used to assess study quality. The presence of publication bias was evaluated using the Trim and Fill method to calculate an adjusted and unbiased overall effect. The systematic review included 36 studies (n = 1449). A random-effects meta-analysis of standardised mean differences yielded an initial 135 individual effect sizes. A composite approach accounted for statistical dependence between effects and yielded 58 individual effects for further analysis. Analysis indicated that MI has a significant effect on performance (g = 0.476). Further analysis revealed significant effects on performance outcomes for MI combined with physical practice and MI alone (g = 0.579 and 0.298, respectively). Subgroup analyses revealed these beneficial effects be moderated by skill complexity, elements of skill performance, and MI delivery type. These results presented in our meta-analysis highlight the overall benefit of MI practice for developing sport-specific motor skills. However, there is a paucity of research on the effects of MI on complex skills and in physical education and sport coaching contexts. Although most studies presented in this review were conducted in controlled research settings, there are clear parallels between the skills practiced in these studies and those implemented in physical education and sport coaching. The efficacy of MI alone presents a potentially beneficial tool when physical practice is not possible or when physical training needs reduction (e.g. in-season sports competition). Therefore, it is encouraged that physical educators and sports coaches collaborate with sport psychology practitioners to investigate the efficacy of the several MI program variables presented in this review.
Tobacco retailer density and smoking behaviour : how are exposure and outcome measures classified? A systematic review
- Baker, John, Lenz, Katrin, Masood, Mohd, Rahman, Muhammad Aziz, Begg, Stephen
- Authors: Baker, John , Lenz, Katrin , Masood, Mohd , Rahman, Muhammad Aziz , Begg, Stephen
- Date: 2023
- Type: Text , Journal article
- Relation: BMC Public Health Vol. 23, no. 1 (2023), p.
- Full Text:
- Reviewed:
- Description: Introduction: To date only a limited number of reviews have focused on how exposure and outcome measures are defined in the existing literature on associations between tobacco retailer density (‘density’) and smoking behaviour (‘smoking’). Therefore this systematic review classified and summarised how both density and smoking variables are operationalised in the existing literature, and provides several methodological recommendations for future density and smoking research. Methods: Two literature searches between March and April 2018 and April 2022 were conducted across 10 databases. Inclusion and exclusion criteria were developed and keyword database searches were undertaken. Studies were imported into Covidence. Cross-sectional studies that met the inclusion criteria were extracted and a quality assessment was undertaken. Studies were categorised according to the density measure used, and smoking was re-categorised using a modified classification tool. Results: Large heterogeneity was found in the operationalisation of both measures in the 47 studies included for analysis. Density was most commonly measured directly from geocoded locations using circular buffers at various distances (n = 14). After smoking was reclassified using a smoking classification tool, past-month smoking was the most common smoking type reported (n = 26). Conclusions: It is recommended that density is measured through length-distance and travel time using the street network and weighted (e.g. by the size of an area), or by using Kernel Density Estimates as these methods provide a more accurate measure of geographical to tobacco and e-cigarette retailer density. The consistent application of a smoking measures classification tool, such as the one developed for this systematic review, would enable better comparisons between studies. Future research should measure exposure and outcome measures in a way that makes them comparable with other studies. Implications: This systematic review provides a strong case for improving data collection and analysis methodologies in studies assessing tobacco retailer density and smoking behaviour to ensure that both exposure and outcome measures are clearly defined and captured. As large heterogeneity was found in the operationalisation of both density and smoking behaviour measures in the studies included for analysis, there is a need for future studies to capture, measure and classify exposure measures accurately, and to define outcome measures in a manner that makes them comparable with other studies. © 2023, BioMed Central Ltd., part of Springer Nature.
- Authors: Baker, John , Lenz, Katrin , Masood, Mohd , Rahman, Muhammad Aziz , Begg, Stephen
- Date: 2023
- Type: Text , Journal article
- Relation: BMC Public Health Vol. 23, no. 1 (2023), p.
- Full Text:
- Reviewed:
- Description: Introduction: To date only a limited number of reviews have focused on how exposure and outcome measures are defined in the existing literature on associations between tobacco retailer density (‘density’) and smoking behaviour (‘smoking’). Therefore this systematic review classified and summarised how both density and smoking variables are operationalised in the existing literature, and provides several methodological recommendations for future density and smoking research. Methods: Two literature searches between March and April 2018 and April 2022 were conducted across 10 databases. Inclusion and exclusion criteria were developed and keyword database searches were undertaken. Studies were imported into Covidence. Cross-sectional studies that met the inclusion criteria were extracted and a quality assessment was undertaken. Studies were categorised according to the density measure used, and smoking was re-categorised using a modified classification tool. Results: Large heterogeneity was found in the operationalisation of both measures in the 47 studies included for analysis. Density was most commonly measured directly from geocoded locations using circular buffers at various distances (n = 14). After smoking was reclassified using a smoking classification tool, past-month smoking was the most common smoking type reported (n = 26). Conclusions: It is recommended that density is measured through length-distance and travel time using the street network and weighted (e.g. by the size of an area), or by using Kernel Density Estimates as these methods provide a more accurate measure of geographical to tobacco and e-cigarette retailer density. The consistent application of a smoking measures classification tool, such as the one developed for this systematic review, would enable better comparisons between studies. Future research should measure exposure and outcome measures in a way that makes them comparable with other studies. Implications: This systematic review provides a strong case for improving data collection and analysis methodologies in studies assessing tobacco retailer density and smoking behaviour to ensure that both exposure and outcome measures are clearly defined and captured. As large heterogeneity was found in the operationalisation of both density and smoking behaviour measures in the studies included for analysis, there is a need for future studies to capture, measure and classify exposure measures accurately, and to define outcome measures in a manner that makes them comparable with other studies. © 2023, BioMed Central Ltd., part of Springer Nature.
Wearable obstacle avoidance electronic travel aids for blind and visually impaired individuals : a systematic review
- Xu, Peijie, Kennedy, Gerard, Zhao, Fei-Yi, Zhang, Wen-Jing, Van Schyndel, Ron
- Authors: Xu, Peijie , Kennedy, Gerard , Zhao, Fei-Yi , Zhang, Wen-Jing , Van Schyndel, Ron
- Date: 2023
- Type: Text , Journal article
- Relation: IEEE Access Vol. 11, no. (2023), p. 66587-66613
- Full Text:
- Reviewed:
- Description: Background Wearable obstacle avoidance electronic travel aids (ETAs) have been developed to assist the safe displacement of blind and visually impaired individuals (BVIs) in indoor/outdoor spaces. This systematic review aimed to understand the strengths and weaknesses of existing ETAs in terms of hardware functionality, cost, and user experience. These elements may influence the usability of the ETAs and are valuable in guiding the development of superior ETAs in the future. Methods Formally published studies designing and developing the wearable obstacle avoidance ETAs were searched for from six databases from their inception to April 2023. The PRISMA 2020 and APISSER guidelines were followed. Results Eighty-nine studies were included for analysis, 41 of which were judged to be of moderate to high quality. Most wearable obstacle avoidance ETAs mainly depend on camera- and ultrasonic-based techniques to achieve perception of the environment. Acoustic feedback was the most common human-computer feedback form used by the ETAs. According to user experience, the efficacy and safety of the device was usually their primary concern. Conclusions Although many conceptualised ETAs have been designed to facilitate BVIs' independent navigation, most of these devices suffer from shortcomings. This is due to the nature and limitations of the various processors, environment detection techniques and human-computer feedback those ETAs are equipped with. Integrating multiple techniques and hardware into one ETA is a way to improve performance, but there is still a need to address the discomfort of wearing the device and the high-cost. Developing an applicable systematic review guideline along with a credible quality assessment tool for these types of studies is also required. © 2013 IEEE.
- Authors: Xu, Peijie , Kennedy, Gerard , Zhao, Fei-Yi , Zhang, Wen-Jing , Van Schyndel, Ron
- Date: 2023
- Type: Text , Journal article
- Relation: IEEE Access Vol. 11, no. (2023), p. 66587-66613
- Full Text:
- Reviewed:
- Description: Background Wearable obstacle avoidance electronic travel aids (ETAs) have been developed to assist the safe displacement of blind and visually impaired individuals (BVIs) in indoor/outdoor spaces. This systematic review aimed to understand the strengths and weaknesses of existing ETAs in terms of hardware functionality, cost, and user experience. These elements may influence the usability of the ETAs and are valuable in guiding the development of superior ETAs in the future. Methods Formally published studies designing and developing the wearable obstacle avoidance ETAs were searched for from six databases from their inception to April 2023. The PRISMA 2020 and APISSER guidelines were followed. Results Eighty-nine studies were included for analysis, 41 of which were judged to be of moderate to high quality. Most wearable obstacle avoidance ETAs mainly depend on camera- and ultrasonic-based techniques to achieve perception of the environment. Acoustic feedback was the most common human-computer feedback form used by the ETAs. According to user experience, the efficacy and safety of the device was usually their primary concern. Conclusions Although many conceptualised ETAs have been designed to facilitate BVIs' independent navigation, most of these devices suffer from shortcomings. This is due to the nature and limitations of the various processors, environment detection techniques and human-computer feedback those ETAs are equipped with. Integrating multiple techniques and hardware into one ETA is a way to improve performance, but there is still a need to address the discomfort of wearing the device and the high-cost. Developing an applicable systematic review guideline along with a credible quality assessment tool for these types of studies is also required. © 2013 IEEE.
- Thangavelu, Dhivya, Tan, Apphia, Cant, Robyn, Chua, Wei, Liaw, Sok
- Authors: Thangavelu, Dhivya , Tan, Apphia , Cant, Robyn , Chua, Wei , Liaw, Sok
- Date: 2022
- Type: Text , Journal article , Review
- Relation: Nurse Education Today Vol. 113, no. (2022), p.
- Full Text: false
- Reviewed:
- Description: Objective: This review aimed to synthesise evidence from experimental studies of the application of digital serious games in developing nursing clinical competence. Design: Systematic review and meta-analysis. Data sources: Eight databases were searched for randomized controlled trials and quasi-experimental studies published in English from 2000 to 2021. Review methods: Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were adopted in this review. Quality appraisal was conducted using Cochrane's Risk of Bias tool and the Joanna Brigg's Institute Critical Appraisal Tool for Quasi-Experimental Designs. A narrative synthesis of studies, and a meta-analysis and subgroup analysis, was performed on the study outcomes. Results: 22 experimental studies including 13 randomized controlled trials and nine quasi-experimental studies were included. Of these, 19 studies examined nursing students and three examined qualified nurses. These studies applied serious games to develop nursing competencies in management of nursing care, clinical reasoning skills, procedural skills, legal practice and quality improvement. Compared with control groups, serious games improved knowledge (SMD = 1.30, 95% CI [0.75, 1.86]) and skills (SMD = 0.38, 95% CI [0.17, 0.60]). Subgroup analysis for both knowledge and skills outcomes demonstrated that serious games were more effective than control groups with either no intervention or other educational interventions. A large effect size (SMD = 1.13, 95% CI [0.91, 1.34]) was found in favour of serious games for improving knowledge scores in management of nursing care. Conclusion: The reviewed studies identified a broad application of digital serious games for developing nursing competencies. The knowledge and skills performance outcomes supported the use of serious games, which were found to be superior to conventional educational interventions. More serious games are required to be incorporated into undergraduate and continuing nursing education for workplace training, with more rigorous studies examining the effect of serious games in improving the quality and safety of clinical nursing practice. © 2022 Elsevier Ltd
Five decades of research on capital budgeting – a systematic review and future research agenda
- Sureka, Riya, Kumar, Satish, Colombage, Sisira, Abedin, Mohammad
- Authors: Sureka, Riya , Kumar, Satish , Colombage, Sisira , Abedin, Mohammad
- Date: 2022
- Type: Text , Journal article
- Relation: Research in International Business and Finance Vol. 60, no. (2022), p.
- Full Text: false
- Reviewed:
- Description: This study synthesizes and reviews the existing literature on capital budgeting (CB) practices and their application to theories, contexts, characteristics and methodology. It aims to identify the prevalent issues and gaps in the literature and provide potential avenues for future research. After comprehensive search and rigorous scrutiny, this review encompasses 185 articles. A systematic literature review (SLR), triangulated with the bibliometric method, is carried out, adopting a meticulous approach to achieve a comprehensive overview of the field. Based on cluster analysis, four distinct themes are identified. Additionally, a conceptual framework is developed that shows the antecedents, moderators and outcomes of research on capital budgeting. Grounded on the detailed content analysis, 11 actionable future research directions are proposed to advance this field of research. © 2021 Elsevier B.V.
Occupational violence and aggression in urgent and critical care in rural health service settings : a systematic review of mixed studies
- Grant, Sharon, Hartanto, Stephanie, Sivasubramaniam, Diane, Heritage, Kaye
- Authors: Grant, Sharon , Hartanto, Stephanie , Sivasubramaniam, Diane , Heritage, Kaye
- Date: 2022
- Type: Text , Journal article , Review
- Relation: Health and Social Care in the Community Vol. 30, no. 6 (2022), p. e3696-e3715
- Full Text:
- Reviewed:
- Description: Rural/remote health services are vulnerable to occupational violence and aggression due to factors such as weapon accessibility, poor network coverage and distance to backup. This systematic review investigated (1) the nature of occupational violence and aggression perpetrated in rural/remote health service urgent care settings and (2) the availability and effectiveness of policies/interventions/recommendations that address occupational violence and aggression in this context. We searched Business Source Complete, CINAHL Complete, Health & Society, APAIS Health, Health Collection, PsycINFO, PubMed, Scopus, SocIndex and Web of Science. Included articles (peer-reviewed, no grey literature and English language) addressed occupational violence and aggression in rural health service urgent care settings. Fifteen articles matched these criteria (total [rural/remote only, where specified] N ~ 2555) and were included in the final analysis. The Mixed Methods Appraisal Tool was applied to assess the risk of bias. A data extraction table and narrative synthesis are presented. The most common occupational violence and aggression type was verbal aggression. The primary perpetrator was patients. Risk factors reflected practitioner age, remoteness, sector, staffing, shift type and area of practice. Precipitating factors were alcohol/drugs, dissatisfaction and mental health conditions. Policy content and limitations and education/training programme effectiveness were not addressed. Community collaboration supported occupational violence and aggression prevention/management. Organisational culture should promote reporting, debriefing and post-incident care for staff well-being. Work environment and job/task design are priorities for safety, but with possible limitations for traumatised clients. Occupational violence and aggression policies/interventions in rural health settings must be systematically evaluated to inform best practices. Co-funded by Swinburne Social Innovation Research Institute Interdisciplinary Seed Funding Scheme and SMART Rural Health Network. © 2022 The Authors. Health and Social Care in the Community published by John Wiley & Sons Ltd.
- Authors: Grant, Sharon , Hartanto, Stephanie , Sivasubramaniam, Diane , Heritage, Kaye
- Date: 2022
- Type: Text , Journal article , Review
- Relation: Health and Social Care in the Community Vol. 30, no. 6 (2022), p. e3696-e3715
- Full Text:
- Reviewed:
- Description: Rural/remote health services are vulnerable to occupational violence and aggression due to factors such as weapon accessibility, poor network coverage and distance to backup. This systematic review investigated (1) the nature of occupational violence and aggression perpetrated in rural/remote health service urgent care settings and (2) the availability and effectiveness of policies/interventions/recommendations that address occupational violence and aggression in this context. We searched Business Source Complete, CINAHL Complete, Health & Society, APAIS Health, Health Collection, PsycINFO, PubMed, Scopus, SocIndex and Web of Science. Included articles (peer-reviewed, no grey literature and English language) addressed occupational violence and aggression in rural health service urgent care settings. Fifteen articles matched these criteria (total [rural/remote only, where specified] N ~ 2555) and were included in the final analysis. The Mixed Methods Appraisal Tool was applied to assess the risk of bias. A data extraction table and narrative synthesis are presented. The most common occupational violence and aggression type was verbal aggression. The primary perpetrator was patients. Risk factors reflected practitioner age, remoteness, sector, staffing, shift type and area of practice. Precipitating factors were alcohol/drugs, dissatisfaction and mental health conditions. Policy content and limitations and education/training programme effectiveness were not addressed. Community collaboration supported occupational violence and aggression prevention/management. Organisational culture should promote reporting, debriefing and post-incident care for staff well-being. Work environment and job/task design are priorities for safety, but with possible limitations for traumatised clients. Occupational violence and aggression policies/interventions in rural health settings must be systematically evaluated to inform best practices. Co-funded by Swinburne Social Innovation Research Institute Interdisciplinary Seed Funding Scheme and SMART Rural Health Network. © 2022 The Authors. Health and Social Care in the Community published by John Wiley & Sons Ltd.
- Xiao, Lily, Chen, Li, Han, Weifeng, Meyer, Claudia, Müller, Amanda, Low, Lee‐Fay, Brijnath, Bianca, Mohammadi, Leila
- Authors: Xiao, Lily , Chen, Li , Han, Weifeng , Meyer, Claudia , Müller, Amanda , Low, Lee‐Fay , Brijnath, Bianca , Mohammadi, Leila
- Date: 2022
- Type: Text , Journal article
- Relation: Nursing Inquiry Vol. 29, no. 3 (2022), p. e12469-n/a
- Full Text: false
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- Description: A large proportion of nursing home residents in developed countries come from ethnic minority groups. Unmet care needs and poor quality of care for this resident population have been widely reported. This systematic review aimed to explore social conditions affecting ethnic minority residents' ability to exercise their autonomy in communication and care while in nursing homes. In total, 19 studies were included in the review. Findings revealed that ethno‐specific nursing homes create the ideal social condition for residents to express their care needs and preferences in a language of choice. In nonethno‐specific nursing homes, staff cultural competence and nursing home commitment to culturally safe care are crucial social conditions that enable this group of residents to fulfil their autonomy in communicating and in participating in their care. In contrast, social conditions that undermine residents' ability to express their care needs and preferences include low levels of staff cultural awareness and cultural desire, negative attitudes towards residents and limited organisational support for staff to improve culturally responsive and culturally safe care. In conclusion, it is important to optimise the social conditions to support ethnic minority residents to communicate their care needs and preferences.
The epidemiology of melioidosis and its association with diabetes mellitus : a systematic review and meta-analysis
- Chowdhury, Sukanta, Barai, Lovely, Afroze, Samira, Ghosh, Probir, Afroz, Farhana, Rahman, Habibur, Ghosh, Sumon, Hossain, Muhammad, Rahman, Mohammed, Das, Pritomy, Rahim, Muhammad
- Authors: Chowdhury, Sukanta , Barai, Lovely , Afroze, Samira , Ghosh, Probir , Afroz, Farhana , Rahman, Habibur , Ghosh, Sumon , Hossain, Muhammad , Rahman, Mohammed , Das, Pritomy , Rahim, Muhammad
- Date: 2022
- Type: Text , Journal article
- Relation: Pathogens Vol. 11, no. 2 (2022), p.
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- Description: Melioidosis is an under-recognized fatal disease in humans, caused by the Gram-negative bacterium Burkholderia pseudomallei. Globally, more than 35,000 human melioidosis cases have been reported since 1911. Soil acts as the natural reservoir of B. pseudomallei. Humans may become infected by this pathogen through direct contact with contaminated soil and/or water. Melioidosis commonly occurs in patients with diabetes mellitus, who increase the occurrence of melioidosis in a population. We carried out a systematic review and meta-analysis to investigate to what extent diabetes mellitus affects the patient in getting melioidosis. We selected 39 articles for meta-analysis. This extensive review also provided the latest updates on the global distribution, clinical manifestation, preexisting underlying diseases, and risk factors of melioidosis. Diabetes mellitus was identified as the predominant predisposing factor for melioidosis in humans. The overall proportion of melioidosis cases having diabetes was 45.68% (95% CI: 44.8–46.57, p < 0.001). Patients with diabetes mellitus were three times more likely to develop melioidosis than patients with no diabetes (RR 3.40, 95% CI: 2.92–3.87, p < 0.001). The other potential risk factors included old age, exposure to soil and water, preexisting underlying diseases (chronic kidney disease, lung disease, heart disease, and thalassemia), and agricultural activities. Evidence-based clinical practice guidelines for melioidosis in patients with diabetes mellitus may be developed and shared with healthcare professionals of melioidosis endemic countries to reduce morbidity. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
- Authors: Chowdhury, Sukanta , Barai, Lovely , Afroze, Samira , Ghosh, Probir , Afroz, Farhana , Rahman, Habibur , Ghosh, Sumon , Hossain, Muhammad , Rahman, Mohammed , Das, Pritomy , Rahim, Muhammad
- Date: 2022
- Type: Text , Journal article
- Relation: Pathogens Vol. 11, no. 2 (2022), p.
- Full Text:
- Reviewed:
- Description: Melioidosis is an under-recognized fatal disease in humans, caused by the Gram-negative bacterium Burkholderia pseudomallei. Globally, more than 35,000 human melioidosis cases have been reported since 1911. Soil acts as the natural reservoir of B. pseudomallei. Humans may become infected by this pathogen through direct contact with contaminated soil and/or water. Melioidosis commonly occurs in patients with diabetes mellitus, who increase the occurrence of melioidosis in a population. We carried out a systematic review and meta-analysis to investigate to what extent diabetes mellitus affects the patient in getting melioidosis. We selected 39 articles for meta-analysis. This extensive review also provided the latest updates on the global distribution, clinical manifestation, preexisting underlying diseases, and risk factors of melioidosis. Diabetes mellitus was identified as the predominant predisposing factor for melioidosis in humans. The overall proportion of melioidosis cases having diabetes was 45.68% (95% CI: 44.8–46.57, p < 0.001). Patients with diabetes mellitus were three times more likely to develop melioidosis than patients with no diabetes (RR 3.40, 95% CI: 2.92–3.87, p < 0.001). The other potential risk factors included old age, exposure to soil and water, preexisting underlying diseases (chronic kidney disease, lung disease, heart disease, and thalassemia), and agricultural activities. Evidence-based clinical practice guidelines for melioidosis in patients with diabetes mellitus may be developed and shared with healthcare professionals of melioidosis endemic countries to reduce morbidity. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
The influence of probiotics on gastrointestinal tract infections among children attending childcare : a systematic review and meta-analysis
- Ahmad, Hafiz, Peck, Blake, Terry, Daniel
- Authors: Ahmad, Hafiz , Peck, Blake , Terry, Daniel
- Date: 2022
- Type: Text , Journal article , Review
- Relation: Journal of Applied Microbiology Vol. 132, no. 3 (2022), p. 1636-1651
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- Description: Current literature related to the impact of probiotics on the incidence of gastrointestinal tract infections (GITIs) has shown mixed results and no systematic review available with pooled analysis exists. Thus, the aim of this systematic review was to provide contemporary evidence regarding the overall and strain-specific influence of probiotics in preventing GITIs among infants and children attending childcare centres. The review shortlisted 18 RCTs after screening through the initial search results of 779 articles. However, only 15 trials were deemed eligible, addressing at least one outcome in the pooled analysis. It is concluded that the supplementation of probiotics (overall effect) may reduce the risk of GITI episode by 26%, with Lacticaseibacillus paracasei, Limosilactobacillus reuteri and Lacticaseibacillus rhamnosus GG being specifically potent probiotic strains in reducing GITI episode, duration of infection and absence from childcare respectively. There is insufficient evidence to determine the effect of Bifidobacterium animalis subsp. lactis BB-12 based on the findings of the trials included in this review. © 2021 The Society for Applied Microbiology
- Authors: Ahmad, Hafiz , Peck, Blake , Terry, Daniel
- Date: 2022
- Type: Text , Journal article , Review
- Relation: Journal of Applied Microbiology Vol. 132, no. 3 (2022), p. 1636-1651
- Full Text:
- Reviewed:
- Description: Current literature related to the impact of probiotics on the incidence of gastrointestinal tract infections (GITIs) has shown mixed results and no systematic review available with pooled analysis exists. Thus, the aim of this systematic review was to provide contemporary evidence regarding the overall and strain-specific influence of probiotics in preventing GITIs among infants and children attending childcare centres. The review shortlisted 18 RCTs after screening through the initial search results of 779 articles. However, only 15 trials were deemed eligible, addressing at least one outcome in the pooled analysis. It is concluded that the supplementation of probiotics (overall effect) may reduce the risk of GITI episode by 26%, with Lacticaseibacillus paracasei, Limosilactobacillus reuteri and Lacticaseibacillus rhamnosus GG being specifically potent probiotic strains in reducing GITI episode, duration of infection and absence from childcare respectively. There is insufficient evidence to determine the effect of Bifidobacterium animalis subsp. lactis BB-12 based on the findings of the trials included in this review. © 2021 The Society for Applied Microbiology
The role of acupuncture in the management of insomnia as a major or residual symptom among patients with active or previous depression : a systematic review and meta-analysis
- Zhao, Fei-Yi, Kennedy, Gerard, Spencer, Sarah, Conduit, Russell, Zhang, Wen-Jing, Fu, Qiang-Qiang, Zheng, Zhen
- Authors: Zhao, Fei-Yi , Kennedy, Gerard , Spencer, Sarah , Conduit, Russell , Zhang, Wen-Jing , Fu, Qiang-Qiang , Zheng, Zhen
- Date: 2022
- Type: Text , Journal article , Review
- Relation: Frontiers in Psychiatry Vol. 13, no. (2022), p.
- Full Text:
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- Description: Background: Due to concerns about risks associated with antidepressants and/or hypnotics, complementary therapies such as acupuncture have been sought by patients with active or previous depression to manage insomnia. This systematic review aimed to clarify if acupuncture is effective and safe enough to be recommended as an alternative or adjuvant therapy to standard care in ameliorating concomitant or residual insomnia, two types of insomnia associated with depression. Methods: Randomized controlled trials (RCTs) of depression-related insomnia (DI) treatment via acupuncture vs. waitlist-control or placebo-/sham-acupuncture and RCTs of DI treatment via acupuncture alone or combined with standard care [Western pharmacotherapy and/or cognitive-behavioral therapy (CBT)] vs. standard care alone were searched for from seven databases from inception to December 2021. Cochrane criteria were followed. Results: Twenty-one studies involving 1,571 participants were analyzed. For insomnia as a major symptom of active depression, meta-analyses suggested that acupuncture significantly reduced the global scores of both the Pittsburg Sleep Quality Index (PSQI) [MD = −3.12, 95% CI (−5.16, −1.08), p < 0.01] and Hamilton Depression Scale (HAMD) [SMD = −2.67, 95% CI (−3.51, −1.84), p < 0.01], in comparison with placebo-acupuncture. When compared with conventional pharmacotherapy (antidepressants and/or hypnotics), the results favored acupuncture in decreasing PSQI [MD = −1.17, 95% CI (−2.26, −0.08), p = 0.03] and HAMD [SMD = −0.47, 95% CI (−0.91, −0.02), p = 0.04]. Acupuncture was comparable to conventional pharmacotherapy in reducing scores of each domain of PSQI. For insomnia as a residual symptom of previous or partially remitted depression, acupuncture conferred a very limited, non-significant therapeutic advantage against sham-/placebo-acupuncture. Whether acupuncture has an add-on effect to conventional pharmacotherapy in this type of insomnia has not been investigated. Also, no study was available to address the efficacy differences between acupuncture and CBT or the synergistic effect of these two therapies. Conclusions: There is a low to moderate level of evidence supporting acupuncture as a safe and effective remedy alternative to or adjuvant to conventional pharmacotherapy (antidepressant and/or hypnotic) in improving insomnia and other depression symptoms among patients with active depression. Furthermore, the patients' complaint of disrupted sleep continuity is most likely to benefit from acupuncture. The benefit of acupuncture on residual insomnia associated with previous or partially remitted depression is limited. Future acupuncture studies need to consider applying optimal dosage and addressing deficiencies in trial quality. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021269880, PROSPERO, identifier: CRD42021269880. Copyright © 2022 Zhao, Kennedy, Spencer, Conduit, Zhang, Fu and Zheng.
- Authors: Zhao, Fei-Yi , Kennedy, Gerard , Spencer, Sarah , Conduit, Russell , Zhang, Wen-Jing , Fu, Qiang-Qiang , Zheng, Zhen
- Date: 2022
- Type: Text , Journal article , Review
- Relation: Frontiers in Psychiatry Vol. 13, no. (2022), p.
- Full Text:
- Reviewed:
- Description: Background: Due to concerns about risks associated with antidepressants and/or hypnotics, complementary therapies such as acupuncture have been sought by patients with active or previous depression to manage insomnia. This systematic review aimed to clarify if acupuncture is effective and safe enough to be recommended as an alternative or adjuvant therapy to standard care in ameliorating concomitant or residual insomnia, two types of insomnia associated with depression. Methods: Randomized controlled trials (RCTs) of depression-related insomnia (DI) treatment via acupuncture vs. waitlist-control or placebo-/sham-acupuncture and RCTs of DI treatment via acupuncture alone or combined with standard care [Western pharmacotherapy and/or cognitive-behavioral therapy (CBT)] vs. standard care alone were searched for from seven databases from inception to December 2021. Cochrane criteria were followed. Results: Twenty-one studies involving 1,571 participants were analyzed. For insomnia as a major symptom of active depression, meta-analyses suggested that acupuncture significantly reduced the global scores of both the Pittsburg Sleep Quality Index (PSQI) [MD = −3.12, 95% CI (−5.16, −1.08), p < 0.01] and Hamilton Depression Scale (HAMD) [SMD = −2.67, 95% CI (−3.51, −1.84), p < 0.01], in comparison with placebo-acupuncture. When compared with conventional pharmacotherapy (antidepressants and/or hypnotics), the results favored acupuncture in decreasing PSQI [MD = −1.17, 95% CI (−2.26, −0.08), p = 0.03] and HAMD [SMD = −0.47, 95% CI (−0.91, −0.02), p = 0.04]. Acupuncture was comparable to conventional pharmacotherapy in reducing scores of each domain of PSQI. For insomnia as a residual symptom of previous or partially remitted depression, acupuncture conferred a very limited, non-significant therapeutic advantage against sham-/placebo-acupuncture. Whether acupuncture has an add-on effect to conventional pharmacotherapy in this type of insomnia has not been investigated. Also, no study was available to address the efficacy differences between acupuncture and CBT or the synergistic effect of these two therapies. Conclusions: There is a low to moderate level of evidence supporting acupuncture as a safe and effective remedy alternative to or adjuvant to conventional pharmacotherapy (antidepressant and/or hypnotic) in improving insomnia and other depression symptoms among patients with active depression. Furthermore, the patients' complaint of disrupted sleep continuity is most likely to benefit from acupuncture. The benefit of acupuncture on residual insomnia associated with previous or partially remitted depression is limited. Future acupuncture studies need to consider applying optimal dosage and addressing deficiencies in trial quality. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021269880, PROSPERO, identifier: CRD42021269880. Copyright © 2022 Zhao, Kennedy, Spencer, Conduit, Zhang, Fu and Zheng.
Viral load monitoring for people living with HIV in the era of test and treat: progress made and challenges ahead – a systematic review
- Pham, Minh, Nguyen, Huy, Anderson, David, Crowe, Suzanne, Luchters, Stanley
- Authors: Pham, Minh , Nguyen, Huy , Anderson, David , Crowe, Suzanne , Luchters, Stanley
- Date: 2022
- Type: Text , Journal article
- Relation: BMC public health Vol. 22, no. 1 (2022), p. 1-1203
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- Description: Abstract Background In 2016, we conducted a systematic review to assess the feasibility of treatment monitoring for people living with HIV (PLHIV) receiving antiretroviral therapy (ART) in low and middle-income countries (LMICs), in line with the 90-90-90 treatment target. By 2020, global estimates suggest the 90-90-90 target, particularly the last 90, remains unattainable in many LMICs. This study aims to review the progress and identify needs for public health interventions to improve viral load monitoring and viral suppression for PLHIV in LMICs. Methods A literature search was conducted using an update of the initial search strategy developed for the 2016 review. Electronic databases (Medline and PubMed) were searched to identify relevant literature published in English between Dec 2015 and August 2021. The primary outcome was initial viral load (VL) monitoring (the proportion of PLHIV on ART and eligible for VL monitoring who received a VL test). Secondary outcomes included follow-up VL monitoring (the proportion of PLHIV who received a follow-up VL after an initial elevated VL test), confirmation of treatment failure (the proportion of PLHIV who had two consecutive elevated VL results) and switching treatment regimen rates (the proportion of PLHIV who switched treatment regimen after confirmation of treatment failure). Results The search strategy identified 1984 non-duplicate records, of which 34 studies were included in the review. Marked variations in initial VL monitoring coverage were reported across study settings/countries (range: 12–93% median: 74% IQR: 46–82%) and study populations (adults (range: 25–96%, median: 67% IQR: 50–84%), children, adolescents/young people (range: 2–94%, median: 72% IQR: 47–85%), and pregnant women (range: 32–82%, median: 57% IQR: 43–71%)). Community-based models reported higher VL monitoring (median: 85%, IQR: 82-88%) compared to decentralised care at primary health facility (median: 64%, IRQ: 48-82%). Suboptimal uptake of follow-up VL monitoring and low regimen switching rates were observed. Conclusions Substantial gaps in VL coverage across study settings and study populations were evident, with limited data availability outside of sub-Saharan Africa. Further research is needed to fill the data gaps. Development and implementation of innovative, community-based interventions are required to improve VL monitoring and address the “failure cascade” in PLHIV on ART who fail to achieve viral suppression.
- Authors: Pham, Minh , Nguyen, Huy , Anderson, David , Crowe, Suzanne , Luchters, Stanley
- Date: 2022
- Type: Text , Journal article
- Relation: BMC public health Vol. 22, no. 1 (2022), p. 1-1203
- Full Text:
- Reviewed:
- Description: Abstract Background In 2016, we conducted a systematic review to assess the feasibility of treatment monitoring for people living with HIV (PLHIV) receiving antiretroviral therapy (ART) in low and middle-income countries (LMICs), in line with the 90-90-90 treatment target. By 2020, global estimates suggest the 90-90-90 target, particularly the last 90, remains unattainable in many LMICs. This study aims to review the progress and identify needs for public health interventions to improve viral load monitoring and viral suppression for PLHIV in LMICs. Methods A literature search was conducted using an update of the initial search strategy developed for the 2016 review. Electronic databases (Medline and PubMed) were searched to identify relevant literature published in English between Dec 2015 and August 2021. The primary outcome was initial viral load (VL) monitoring (the proportion of PLHIV on ART and eligible for VL monitoring who received a VL test). Secondary outcomes included follow-up VL monitoring (the proportion of PLHIV who received a follow-up VL after an initial elevated VL test), confirmation of treatment failure (the proportion of PLHIV who had two consecutive elevated VL results) and switching treatment regimen rates (the proportion of PLHIV who switched treatment regimen after confirmation of treatment failure). Results The search strategy identified 1984 non-duplicate records, of which 34 studies were included in the review. Marked variations in initial VL monitoring coverage were reported across study settings/countries (range: 12–93% median: 74% IQR: 46–82%) and study populations (adults (range: 25–96%, median: 67% IQR: 50–84%), children, adolescents/young people (range: 2–94%, median: 72% IQR: 47–85%), and pregnant women (range: 32–82%, median: 57% IQR: 43–71%)). Community-based models reported higher VL monitoring (median: 85%, IQR: 82-88%) compared to decentralised care at primary health facility (median: 64%, IRQ: 48-82%). Suboptimal uptake of follow-up VL monitoring and low regimen switching rates were observed. Conclusions Substantial gaps in VL coverage across study settings and study populations were evident, with limited data availability outside of sub-Saharan Africa. Further research is needed to fill the data gaps. Development and implementation of innovative, community-based interventions are required to improve VL monitoring and address the “failure cascade” in PLHIV on ART who fail to achieve viral suppression.
A systematic review of public transport accessibility for people using mobility devices
- Unsworth, Carolyn, So, Man, Chua, Julian, Gudimetla, Prasad, Naweed, Anjum
- Authors: Unsworth, Carolyn , So, Man , Chua, Julian , Gudimetla, Prasad , Naweed, Anjum
- Date: 2021
- Type: Text , Journal article , Review
- Relation: Disability and Rehabilitation Vol. 43, no. 16 (2021), p. 2253-2267
- Full Text: false
- Reviewed:
- Description: Purpose: Being able to access public transport is vital for mobility device users as this is an affordable way of maintaining community connections and participating in activities that promote quality of life. This systematic review investigated literature on public transport access for people using mobility devices, excluding transit restraint and securement literature. Materials and methods: A systematic review of the peer-reviewed literature in English from 1995 to 2019, with critical appraisal and narrative synthesis. Results: Twenty-six articles were identified, including 14 studies investigating user experiences, seven examining bus formats and floor layouts, and five focusing on bus ramp incidents and optimal design. Studies were generally observational and descriptive, with 12 including analysis of video data. Conclusion: This is the first systematic review of literature related to the accessibility of public transport for people using mobility devices. Topics such as ramp access have been relatively well-researched, as have the experiences of users. However, many gaps remain and there is a need for research to; address the barriers identified through user experiences, discern the best access to stations and stops, as well as floor formats for people to ingress, manoeuvre and egress from a variety of transport modes, and promote universal design principles in the transport sector. Rehabilitation professionals can use the findings of this review to advocate for, and support people using mobility devices to successfully negotiate public transport.Implications for Rehabilitation Accessible public transport is vital to enable people using mobility devices to remain connected in their communities. Despite increased international awareness and adoption of accessibility features by the public transport sector to improve getting to a stop, ingress, manoeuvrability within and egress from conveyances, access for people using wheeled mobility devices cannot be assumed. When prescribing new wheeled mobility devices with clients, rehabilitation professionals and users need to consider public transport access and the suitability of different devices for this purpose. Rehabilitation professionals can undertake skills training with people using wheeled mobility devices to test out access prior to independent travel on public transport and develop strategies to overcome any barriers. © 2019 Informa UK Limited, trading as Taylor & Francis Group.
Acupuncture as an independent or adjuvant management to standard care for perimenopausal depression : a systematic review and meta-analysis
- Zhao, Fei, Fu, Qiang-Qiang, Kennedy, Gerard, Conduit, Russell, Zhang, Wen-Jing, Zheng, Zhen
- Authors: Zhao, Fei , Fu, Qiang-Qiang , Kennedy, Gerard , Conduit, Russell , Zhang, Wen-Jing , Zheng, Zhen
- Date: 2021
- Type: Text , Journal article , Review
- Relation: Frontiers in Psychiatry Vol. 12, no. (2021), p.
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- Description: Background: Many women with perimenopausal depression (PMD) have sought alternative therapies such as acupuncture because of concerns about risks associated with antidepressant and hormone replacement therapy (HRT). This systematic review aimed to clarify if acupuncture is effective for PMD compared with waitlist control or placebo/sham acupuncture, and if acupuncture alone or combined with standard care (antidepressant and/or HRT) is more effective in ameliorating PMD in comparison with standard care alone. Methods: Randomized controlled trials (RCTs) of PMD treatment via acupuncture vs. waitlist control or placebo/sham acupuncture, and RCTs of PMD treatment via acupuncture alone or combined with Western pharmacotherapy vs. Western pharmacotherapy were searched for from seven databases from inception to December 2020. Cochrane criteria were followed. Results: Twenty-five studies involving 2,213 women were analyzed. Meta-analyses indicated that acupuncture significantly reduced the global scores of Hamilton Depression Scale (HAMD) [standardized mean difference (SMD) = −0.54, 95% CI (−0.91, −0.16), p < 0.01], compared with standard care. The therapeutic effect of acupuncture maintained at 2-, 4-, and 12-week follow-ups. Acupuncture combined with standard care was more effective than standard care alone in decreasing HAMD scores [SMD = −0.82, 95% CI (−1.07, −0.58), p < 0.01]. Too few RCTs were available to assess the clinical efficacy differences between acupuncture and placebo/sham acupuncture or HRT alone. Acupuncture also showed better effects in decreasing Kupperman index (KI) scores, whether compared with antidepressant alone [MD = −4.55, 95% CI (−8.46, −0.65), p = 0.02] or antidepressant combined with HRT [MD = −0.89, 95% CI (−1.34, −0.43), p < 0.01]. Conclusions: In comparison with standard care, acupuncture alone or combined with standard care was associated with significant improvements in PMD and reductions of other menopausal symptoms. This finding suggests that acupuncture may be a useful addition to treatment for PMD. © Copyright © 2021 Zhao, Fu, Kennedy, Conduit, Zhang and Zheng.
- Authors: Zhao, Fei , Fu, Qiang-Qiang , Kennedy, Gerard , Conduit, Russell , Zhang, Wen-Jing , Zheng, Zhen
- Date: 2021
- Type: Text , Journal article , Review
- Relation: Frontiers in Psychiatry Vol. 12, no. (2021), p.
- Full Text:
- Reviewed:
- Description: Background: Many women with perimenopausal depression (PMD) have sought alternative therapies such as acupuncture because of concerns about risks associated with antidepressant and hormone replacement therapy (HRT). This systematic review aimed to clarify if acupuncture is effective for PMD compared with waitlist control or placebo/sham acupuncture, and if acupuncture alone or combined with standard care (antidepressant and/or HRT) is more effective in ameliorating PMD in comparison with standard care alone. Methods: Randomized controlled trials (RCTs) of PMD treatment via acupuncture vs. waitlist control or placebo/sham acupuncture, and RCTs of PMD treatment via acupuncture alone or combined with Western pharmacotherapy vs. Western pharmacotherapy were searched for from seven databases from inception to December 2020. Cochrane criteria were followed. Results: Twenty-five studies involving 2,213 women were analyzed. Meta-analyses indicated that acupuncture significantly reduced the global scores of Hamilton Depression Scale (HAMD) [standardized mean difference (SMD) = −0.54, 95% CI (−0.91, −0.16), p < 0.01], compared with standard care. The therapeutic effect of acupuncture maintained at 2-, 4-, and 12-week follow-ups. Acupuncture combined with standard care was more effective than standard care alone in decreasing HAMD scores [SMD = −0.82, 95% CI (−1.07, −0.58), p < 0.01]. Too few RCTs were available to assess the clinical efficacy differences between acupuncture and placebo/sham acupuncture or HRT alone. Acupuncture also showed better effects in decreasing Kupperman index (KI) scores, whether compared with antidepressant alone [MD = −4.55, 95% CI (−8.46, −0.65), p = 0.02] or antidepressant combined with HRT [MD = −0.89, 95% CI (−1.34, −0.43), p < 0.01]. Conclusions: In comparison with standard care, acupuncture alone or combined with standard care was associated with significant improvements in PMD and reductions of other menopausal symptoms. This finding suggests that acupuncture may be a useful addition to treatment for PMD. © Copyright © 2021 Zhao, Fu, Kennedy, Conduit, Zhang and Zheng.
Factors contributing to the recruitment and retention of rural pharmacist workforce: a systematic review
- Terry, Daniel, Peck, Blake, Hills, Danny, Baker, Ed, Schmitz, David
- Authors: Terry, Daniel , Peck, Blake , Hills, Danny , Baker, Ed , Schmitz, David
- Date: 2021
- Type: Text , Journal article
- Relation: BMC Health Services Research Vol. 21, no. 1 (2021), p.
- Full Text:
- Reviewed:
- Description: Background: Recruiting and retaining medical, nursing, and allied health professionals in rural and remote areas is a worldwide challenge, compromising continuity of care and population health outcomes in these locations. Specifically, pharmacists play an essential and accessible frontline healthcare role, and are often the first point of contact for health concerns. Despite several incentives, there remains a maldistribution and undersupply of pharmacists in rural and remote areas across many parts of the world. Although current systematic reviews have focussed on factors affecting pharmacists’ retention generally, literature specifically focused on rural pharmacist workforce in a global context remains limited. The aim of this systematic review is to identify factors associated with recruitment and retention of the pharmacist workforce in rural and remote settings. Better understanding of these contributors will inform more effective interventional strategies to resolve pharmacist workforce shortages. Methods: A systematic search of primary studies was conducted in online databases, including Medline, Embase, CINAHL, Scopus, Web of Science and PsycINFO, and by hand-searching of reference lists. Eligible studies were identified based on predefined inclusion/exclusion criteria and methodological quality criteria, utilising the Critical Appraisal Skills Programme (CASP) and Good Reporting of A Mixed Methods Study (GRAMMS) checklists. Results: The final review included 13 studies, with quantitative, qualitative, or mixed methods research design. Study-specific factors associated with recruitment and retention of pharmacists in rural practice were identified and grouped into five main themes: geographic and family-related, economic and resources, scope of practice or skills development, the practice environment, and community and practice support factors. Conclusions: The results provide critical insights into the complexities of rural recruitment and retention of pharmacists and confirms the need for flexible yet multifaceted responses to overcoming rural pharmacist workforce challenges. Overall, the results provide an opportunity for rural communities and health services to better identify key strengths and challenges unique to the rural and remote pharmacist workforce that may be augmented to guide more focussed recruitment and retention endeavours. © 2021, The Author(s). **Please note that there are multiple authors for this article therefore only the name of the Federation University Australia affiliates “Daniel Terry, Blake Peck, Danny Hills, Ed Baker and David Schmitz” are provided in this record** Correction to: Factors contributing to the recruitment and retention of rural pharmacist workforce: a systematic review (BMC Health Services Research, (2021), 21, 1, (1052), 10.1186/s12913-021-07072-1)
- Authors: Terry, Daniel , Peck, Blake , Hills, Danny , Baker, Ed , Schmitz, David
- Date: 2021
- Type: Text , Journal article
- Relation: BMC Health Services Research Vol. 21, no. 1 (2021), p.
- Full Text:
- Reviewed:
- Description: Background: Recruiting and retaining medical, nursing, and allied health professionals in rural and remote areas is a worldwide challenge, compromising continuity of care and population health outcomes in these locations. Specifically, pharmacists play an essential and accessible frontline healthcare role, and are often the first point of contact for health concerns. Despite several incentives, there remains a maldistribution and undersupply of pharmacists in rural and remote areas across many parts of the world. Although current systematic reviews have focussed on factors affecting pharmacists’ retention generally, literature specifically focused on rural pharmacist workforce in a global context remains limited. The aim of this systematic review is to identify factors associated with recruitment and retention of the pharmacist workforce in rural and remote settings. Better understanding of these contributors will inform more effective interventional strategies to resolve pharmacist workforce shortages. Methods: A systematic search of primary studies was conducted in online databases, including Medline, Embase, CINAHL, Scopus, Web of Science and PsycINFO, and by hand-searching of reference lists. Eligible studies were identified based on predefined inclusion/exclusion criteria and methodological quality criteria, utilising the Critical Appraisal Skills Programme (CASP) and Good Reporting of A Mixed Methods Study (GRAMMS) checklists. Results: The final review included 13 studies, with quantitative, qualitative, or mixed methods research design. Study-specific factors associated with recruitment and retention of pharmacists in rural practice were identified and grouped into five main themes: geographic and family-related, economic and resources, scope of practice or skills development, the practice environment, and community and practice support factors. Conclusions: The results provide critical insights into the complexities of rural recruitment and retention of pharmacists and confirms the need for flexible yet multifaceted responses to overcoming rural pharmacist workforce challenges. Overall, the results provide an opportunity for rural communities and health services to better identify key strengths and challenges unique to the rural and remote pharmacist workforce that may be augmented to guide more focussed recruitment and retention endeavours. © 2021, The Author(s). **Please note that there are multiple authors for this article therefore only the name of the Federation University Australia affiliates “Daniel Terry, Blake Peck, Danny Hills, Ed Baker and David Schmitz” are provided in this record** Correction to: Factors contributing to the recruitment and retention of rural pharmacist workforce: a systematic review (BMC Health Services Research, (2021), 21, 1, (1052), 10.1186/s12913-021-07072-1)
Health beliefs and chronic illnesses of refugees : a systematic review
- Shahin, Wejdan, Stupans, Ieva, Kennedy, Gerard
- Authors: Shahin, Wejdan , Stupans, Ieva , Kennedy, Gerard
- Date: 2021
- Type: Text , Journal article
- Relation: Ethnicity and Health Vol. 26, no. 5 (2021), p. 756-768
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- Description: Objective: To evaluate beliefs, and attitudes about health of refugees with chronic conditions such as diabetes mellitus type 2, hypertension, chronic obstructive pulmonary disease, and posttraumatic stress disorder and the consequent effects on self-care in comparison to resident populations. Design: A systematic review methodology was used. PubMed, Embase, PsycINFO and CINAHL databases were searched for relevant articles. The main terms analysed were health beliefs, chronic conditions and refugee populations. From 844 articles, 45 were retained for further assessment, and finally 5 met the inclusion criteria. Results: Differences in the health beliefs, attitudes and self-care management approaches of refugees compared to resident populations were identified in two studies. The remaining three papers did not make comparisons between the refugees and the resident population, nor did they specifically explore the refugees’ health beliefs. Of the five studies, three were carried out in Sweden and two in the US. Refugees who have poorer mental and physical health as well as higher prevalence of chronic diseases than the populations among which they resettle seem to lack the knowledge about their illness, symptoms and self-management and thus are less able to control their chronic conditions. Conclusion: The findings highlighted the deficiency in the literature of studies which examine health beliefs and attitudes of minority groups such as refugees who have chronic conditions. The findings also gave insight to the need for a distinctive understanding of refugee health and the management of chronic conditions in comparison to other non-refugee migrant groups. Further research is needed to fully understand the differences between refugees and local populations in terms health beliefs, chronic disease and self-management. © 2018 Informa UK Limited, trading as Taylor & Francis Group.
Palliative care education and its effectiveness: a systematic review
- Li, Wendy, Chhabra, Jasleen, Singh, Smita.
- Authors: Li, Wendy , Chhabra, Jasleen , Singh, Smita.
- Date: 2021
- Type: Text , Journal article
- Relation: Public Health Vol. 194, no. (2021), p. 96-108
- Full Text: false
- Reviewed:
- Description: Palliative care education (PCE) is an important public health approach to palliative care and is crucial to improving its utilisation. The present study aims to develop a comprehensive understanding of PCE and its effectiveness. A systematic review approach, including narrative synthesis, was used to review qualitative and quantitative studies published in the English language between January 1969 and January 2019, focussing on PCE programs. Thirty-nine research studies were included in the systematic review. The target audience of the included studies were mostly healthcare professionals, followed by family caregivers. Definitions of death and palliative care, symptom management and communication were leading themes in the reviewed PCE programs. The educational resources used in PCE programs were mainly self-developed teaching materials, with some programs utilising eLearning resources. The included PCE programs were effective in improving knowledge, attitude and confidence in palliative care and the satisfaction of participant learning experience. PCE is a useful tool to improve knowledge of, confidence in and attitudes towards palliative care amongst healthcare professionals and carers. To make palliative care a public health issue, PCE should be expanded to the public and policy-makers.
The Australian digital online farm trials database increases the quality of systematic reviews and meta-analyses in grains crop research
- Authors: Walters, Judi , Light, Kate
- Date: 2021
- Type: Text , Journal article , Review
- Relation: Crop and Pasture Science Vol. 72, no. 10 (2021), p. 789-800
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- Description: Synthesis and analysis of past cropping research can provide valuable information to direct future decisions around crop management. Systematic reviews and meta-analyses are considered gold standards in the synthesis and analysis of scientific research because they distil large amounts of information about complex issues, provide a summary of knowledge to date, and identify knowledge gaps. However, several issues concerning the methodologies employed to conduct systematic reviews have been identified; among them is the risk of publication bias when a review relies too heavily on 'white' literature from published academic sources and in so doing fails identify relevant 'grey' literature. Grey literature is inherently difficult to identify and collect, but forms a large portion of information available in many fields including agricultural-based research within Australia. The Online Farm Trials (OFT) database is a digital database of crop research field trial data from across Australia that has the potential for use as a discipline-specific source of grey literature to inform systematic reviews and meta-analyses. Using a case study approach to investigate the amount of information available on time of sowing (sowing date) on crop yield across Australia, we demonstrate that the OFT database provides easy access to transparent and reproducible search results similar to other commonly used academic databases. © 2021 Journal Compilation
- Authors: Walters, Judi , Light, Kate
- Date: 2021
- Type: Text , Journal article , Review
- Relation: Crop and Pasture Science Vol. 72, no. 10 (2021), p. 789-800
- Full Text:
- Reviewed:
- Description: Synthesis and analysis of past cropping research can provide valuable information to direct future decisions around crop management. Systematic reviews and meta-analyses are considered gold standards in the synthesis and analysis of scientific research because they distil large amounts of information about complex issues, provide a summary of knowledge to date, and identify knowledge gaps. However, several issues concerning the methodologies employed to conduct systematic reviews have been identified; among them is the risk of publication bias when a review relies too heavily on 'white' literature from published academic sources and in so doing fails identify relevant 'grey' literature. Grey literature is inherently difficult to identify and collect, but forms a large portion of information available in many fields including agricultural-based research within Australia. The Online Farm Trials (OFT) database is a digital database of crop research field trial data from across Australia that has the potential for use as a discipline-specific source of grey literature to inform systematic reviews and meta-analyses. Using a case study approach to investigate the amount of information available on time of sowing (sowing date) on crop yield across Australia, we demonstrate that the OFT database provides easy access to transparent and reproducible search results similar to other commonly used academic databases. © 2021 Journal Compilation