- Title
- Mathematical formulas for some cross-B structures of human Aβ protein
- Creator
- Zhang, Jiapu
- Date
- 2016
- Type
- Text; Journal article
- Identifier
- http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/169277
- Identifier
- vital:14007
- Identifier
-
https://doi.org/10.4172/2161-0444.1000369
- Identifier
- ISBN:2161-0444
- Abstract
- For amyloid fibril cross-β structures of Aβ human protein, we find theoretical calculations are agreeing with laboratory X-ray crystallography experiments. This mini article summarized mathematical formulas of amyloid fibril cross-β structures of segments of human Aβ protein. These formulas are accurate and correct some data in the Protein Data Bank (PDB). However, more mathematical formulas for core Chains AB (PDB IDs: 3OW9, 3PZZ, 2OKZ), or ABGH (PDB IDs: 3OVJ, 2Y3J, 2Y3K, 2Y3L) (or ABCD (PDB ID: 2ONA)) are still needed to present and optimize.
- Publisher
- OMICS International for Nigerian Society of Biochemistry and Molecular Biology
- Relation
- Medicinal chemistry Vol. 6, no. 5 (2016), p. 1-7
- Rights
- http://creativecommons.org/licenses/by/4.0/
- Rights
- Copyright © 2016 Zhang J. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Rights
- Open Access
- Rights
- This metadata is freely available under a CCO license
- Subject
- Human Aβ protein; Cross-β structures; Theoretical calculations; Experimental laboratories; Mathematical formulas
- Full Text
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