http://researchonline.federation.edu.au/vital/access/manager/Index ${session.getAttribute("locale")} 5 Increasing chloramphenicol resistance in Streptococcus pneumoniae isolates from Papua New Guinean Children with acute bacterial meningitis http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:12939 100 h at a MIC of ≥4 μg/ml was approximately 50%. All isolates were ceftriaxone sensitive. These data support ceftriaxone rather than conventional chloramphenicol for all PNG children with suspected ABM.]]> Wed 07 Apr 2021 14:01:08 AEST ]]> Influenza viruses with B/Yamagata- and B/Victoria-like neuraminidases are differentially affected by mutations that alter antiviral susceptibility http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:12923 Wed 07 Apr 2021 14:01:07 AEST ]]> Paradoxical effect of 1-(1-naphthylmethyl)-piperazine on resistance to tetracyclines in multidrug-resistant Acinetobacter baumannii http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:7155 Wed 07 Apr 2021 13:46:39 AEST ]]> Plasmids imparting sulfonamide resistance in Escherichia coli: Implications for persistence http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:7154 97%) national decline in the rate of prescription of sulfonamides in the 1990s. To investigate potential mechanisms accounting for this persistence, we characterized plasmids carrying sul2, the most prevalent determinant of sulfonamide resistance. Among 33 conjugative and 5 nonconjugative plasmids carrying sul2, resistance to other antimicrobial agents was common, but the spectrum of resistance profiles was diverse: 82%, 74%, and 45% carried resistance to ampicillin, streptomycin, and trimethoprim, respectively. Resistance to mercury was carried by 33% of the plasmids, but none conferred significant resistance to silver or to any of three disinfectants tested. The potential virulence genes iutA (aerobactin system) and traT (serum survival) were carried by 21% and 36% of the plasmids, respectively. The 33 conjugative plasmids belonged to five different incompatibility groups, FIB, B/O, I1, K/B, and P (42%, 33%, 9%, 3% and 3%, respectively), with 3 plasmids being unassigned, and to 19 similarity groups on the basis of their restriction profiles. The sequences flanking sul2 were diverse and suggested more than one mechanism of genetic mobility. The five nonconjugative plasmids were all related to p9123 (pBP1), which was previously found to confer a fitness advantage on its host. We propose that the persistence of sul2, despite the reduced rate of prescription of sulfonamides, is due to a combination of coselection by antibiotics still in common use, a lack of a selective disadvantage in sul2 carriage, and the genetic mobility of sul2. Copyright © 2009, American Society for Microbiology. All Rights Reserved.]]> Wed 07 Apr 2021 13:46:39 AEST ]]> A novel plasmid-mediated polymyxin resistance determinant (mcr-1.8) in escherichia coli recovered from broiler chickens in Brunei Darussalam http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:14237 Thu 09 Dec 2021 16:01:04 AEDT ]]>