http://researchonline.federation.edu.au/vital/access/manager/Index ${session.getAttribute("locale")} 5 http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:14097 75% of children vaccinated with either PCV10 or PCV13. Children carried a total of 65 different pneumococcal serotypes (plus nonserotypeable). At 4 months of age, 92% (95% confidence interval [CI] 85–96) of children vaccinated with PCV10 and 81% (95% CI 72–88) vaccinated with PCV13 were pneumococcal carriers (P = .023), whereas no differences were seen at 9 months of age, or for NTHi carriage. Both vaccines were well tolerated and not associated with serious adverse events. Conclusions. Infant vaccination with 3 doses of PCV10 or PCV13 is safe and immunogenic in a highly endemic setting; however, to significantly reduce pneumococcal disease in these settings, PCVs with broader serotype coverage and potency to reduce pneumococcal carriage are needed. Clinical Trials Registration. NCT01619462.]]> Wed 07 Apr 2021 14:02:11 AEST ]]> http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:13455 Wed 07 Apr 2021 14:01:36 AEST ]]> http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:13442 Wed 07 Apr 2021 14:01:35 AEST ]]> http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:13447 Wed 07 Apr 2021 14:01:35 AEST ]]> http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:13453 Wed 07 Apr 2021 14:01:35 AEST ]]> http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:12970 Wed 07 Apr 2021 14:01:10 AEST ]]> http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:12934 Wed 07 Apr 2021 14:01:08 AEST ]]> http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:12922 Wed 07 Apr 2021 14:01:07 AEST ]]> http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:12620 Wed 07 Apr 2021 14:00:51 AEST ]]> http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:12560 15,000 cases of cholera were reported, resulting in approximately 500 deaths. The origin of this outbreak is unknown, but considering the remote location of the initial outbreak an infected international traveller is unlikely to be the source. In this paper we review the characteristics of the PNG cholera outbreak and discuss the ongoing threat of cholera to the country and the region.]]> Wed 07 Apr 2021 14:00:48 AEST ]]> http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:11077 100 colonies from each sample). For the alternate serotyping methods, the overall sensitivity ranged from 1% to 99% (reference method 98%), and PPV from 8% to 100% (reference method 100%), when testing the spiked samples. Fifteen methods had ≥70% sensitivity to detect the dominant (major) serotype, whilst only eight methods had ≥70% sensitivity to detect minor serotypes. For the field samples, the overall sensitivity ranged from 74.2% to 95.8% (reference method 93.8%), and PPV from 82.2% to 96.4% (reference method 99.6%). The microarray had the highest sensitivity (95.8%) and high PPV (93.7%). The major limitation of this study is that not all of the available alternative serotyping methods were included. Conclusions: Most methods were able to detect the dominant serotype in a sample, but many performed poorly in detecting the minor serotype populations. Microarray with a culture amplification step was the top-performing method. Results from this comprehensive evaluation will inform future vaccine evaluation and impact studies, particularly in low-income settings, where pneumococcal disease burden remains high. © 2015 Satzke et al. *For a complete list of authors, please see acknowledgments in the published article.]]> Wed 07 Apr 2021 13:56:24 AEST ]]> http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:12781 Wed 05 May 2021 11:59:09 AEST ]]> http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:12540 48 hours post-admission and thus considered nosocomially acquired. These data suggest two distinct patterns of bacterial infection in PNG surgical inpatients that have implications for national antibiotic prescription guidelines.]]> Wed 05 May 2021 11:39:22 AEST ]]> http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:15610 Tue 04 Jan 2022 11:22:14 AEDT ]]> http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:14840 Thu 19 May 2022 12:11:29 AEST ]]> http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:12929 Thu 03 Feb 2022 12:53:21 AEDT ]]>