http://researchonline.federation.edu.au/vital/access/manager/Index ${session.getAttribute("locale")} 5 The penetration of methanol into bovine cardiac and hepatic tissues is faster than ethanol and formalin http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:12957 0.05). The penetration rate of formalin was similar to that of ethanol in both tissues however it was significantly slower than methanol (N=4, P<0.005 in the heart; P<0.001 in the liver). The mean penetration coefficients of methanol, formalin and ethanol in the heart tissue were 2.609, 1.994 and 1.801, respectively, and 3.012, 2.153 and 2.113, respectively, in the liver tissue. The penetration coefficient of methanol was significantly greater than that of ethanol or formalin in both tissues (P<0.001 for each comparison). In conclusion, methanol penetrates tissue significantly faster than ethanol and formalin.]]> Wed 07 Apr 2021 14:01:09 AEST ]]> The association between serum uric acid and blood pressure in different age groups in a healthy Chinese cohort http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:12914 7 mg/dL in men and >6 mg/dL in women. The association between sUA concentration and SBP and DBP was examined using Pearson's correlation test, multivariate linear regression, and logistic regression analysis. The prevalence of hypertension and HUA increased with age (P < .001). Hypertension was more common in participants that had HUA than in those that did not (38.95% vs 30.16%, P = .02). Higher sUA was significantly associated with higher SBP and DBP in the 41- to 50-year-old participants (SBP, β = 0.35, P < .001; DBP, β = .29, P < .001; after adjustment for age, sex, total cholesterol, estimated glomerular filtration rate, and fasting plasma glucose). HUA was also a risk factor for hypertension in this age group (odds ratio 1.425, 95% confidence interval, 1.217-1.668, P < .001). There was no association between sUA concentration and SBP and DBP in the other age groups. In this population of healthy Chinese participants, sUA concentration was positively associated with hypertension only in the 41- to 50-year-old group. Lowering uric acid in this age group may help to reduce the incidence of hypertension.]]> Wed 07 Apr 2021 14:01:07 AEST ]]> Reduced renal function may explain the higher prevalence of hyperuricemia in older people http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:14995 Wed 07 Apr 2021 13:24:57 AEST ]]> Both low and high levels of low-density lipoprotein cholesterol are risk factors for diabetes diagnosis in Chinese adults http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:18705 3.77 mmol/L, respectively. Prevalence of diabetes was higher in people with hypocholesterolemia or hypercholesterolemia than that in people with normocholesterolemia. Hypocholesterolemia was associated with an increased multivariable-adjusted risk for diabetes diagnosis (odds ratio, 1.57 95% confidence interval, 1.18–2.08), and so was hypercholesterolemia (odds ratio, 1.29 95% confidence interval, 1.10–1.51). The results remained significant after exclusion of those who took lipid-lowering drugs from the analysis. This study demonstrated that both low and high levels of LDL-C were associated with a higher risk of diabetes diagnosis. Patients with either high or low LDL-C may need to be closely monitored for the risk of diabetes .]]> Tue 12 Dec 2023 14:19:16 AEDT ]]> Adjustment for body mass index changes inverse associations of HDL-cholesterol with blood pressure and hypertension to positive associations http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:16947 Mon 11 Sep 2023 10:07:58 AEST ]]> Hypouricemia is a risk factor for diabetes in Chinese adults http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:17430 Mon 11 Sep 2023 10:05:29 AEST ]]> An improved 3-(4,5-dmethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl )-2H-tetrazolium proliferation assay to overcome the interference of hydralazine http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:15089 = 10 mu M) increased absorbance in a concentration-dependent manner. The modified MTS assay produced results consistent with trypan blue exclusion and microscopy. In conclusion, a simple modification of the standard MTS assay overcame the interference of hydralazine and may be useful to avoid interference from other tested compounds.]]> Mon 10 Jan 2022 15:16:15 AEDT ]]>