${session.getAttribute("locale")} 5 Identification of fromiamycalin and halaminol A from Australian marine sponge extracts with anthelmintic activity against haemonchus contortus = 100 mu M). Investigation of the active fractions from the two Haliclona collections led to identification of a mixture of amino alcohol lipids, and, subsequently, a known natural product halaminol A (5). Anthelmintic profiling showed that 5 had limited potency at inhibiting larval development and motility. These data indicate that fromiamycalin, other related pentacyclic guanidine alkaloids and/or halaminols could have potential as anthelmintics following future medicinal chemistry efforts.]]> Wed 07 Apr 2021 14:02:28 AEST ]]> Selected alpha-pyrones from the plants Cryptocarya novoguineensis (Lauraceae) and Piper methysticum (Piperaceae) with activity against Haemonchus contortus in vitro Wed 07 Apr 2021 14:02:14 AEST ]]> Deguelin exerts potent nematocidal activity via the mitochondrial respiratory chain Wed 07 Apr 2021 14:01:13 AEST ]]> Screening of a small, well-curated natural product-based library identifies two rotenoids with potent nematocidal activity against Haemonchus contortus Wed 07 Apr 2021 14:00:28 AEST ]]> Advances in the discovery and development of anthelmintics by harnessing natural product scaffolds Thu 26 Aug 2021 12:27:56 AEST ]]>