http://researchonline.federation.edu.au/vital/access/manager/Index ${session.getAttribute("locale")} 5 Neural suppression of miRNA-181a in the kidney elevates renin expression and exacerbates hypertension in Schlager mice http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:14837 Wed 25 Nov 2020 10:04:34 AEDT ]]> May measurement month 2018 : A pragmatic global screening campaign to raise awareness of blood pressure by the international society of hypertension http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:14048 Wed 07 Apr 2021 14:02:08 AEST ]]> Renal nerves contribute to hypertension in Schlager BPH/2J mice http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:13780 0.1). The depressor response to pentolinium was greater in BPH/2J than BPN/3J, but in both cases the response in RD mice was similar to sham. Enalaprilat decreased MAP more in RD BPH/2J compared to sham (−12 vs −3 mmHg, P < 0.001) but had no effect in BPN/3J. RD reduced renal noradrenaline in both strains but more so in BPH/2J. RD reduced renin mRNA and protein, but not plasma renin in BPH/2J to levels comparable with BPN/3J mice. We conclude that renal nerves contribute to hypertension in BPH mice as RD induced a sustained fall in MAP, which was associated with a reduction of intrarenal renin expression. The lack of inhibition of the depressor effects of pentolinium and enalaprilat by RD suggests that vasoconstrictor effects of the SNS or RAS are not involved.]]> Wed 07 Apr 2021 14:01:53 AEST ]]> A multi-omics glimpse into the biology of arterial stiffness http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:10341 Wed 07 Apr 2021 13:55:41 AEST ]]> A novel interaction between sympathetic overactivity and aberrant regulation of renin by miR-181a in BPH/2J genetically hypertensive mice http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:6926 Wed 07 Apr 2021 13:46:28 AEST ]]> May measurement month 2019 the global blood pressure screening campaign of the International Society of Hypertension http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:14703 = 18 years) recruited through opportunistic sampling were screened at sites in 92 countries during May 2019. Ideally, 3 blood pressure readings were measured for each participant, and data on lifestyle factors and comorbidities were collected. Hypertension was defined as a systolic blood pressure >= 140 mm Hg, or a diastolic blood pressure >= 90 mm Hg (mean of the second and third readings) or taking antihypertensive medication. When necessary, multiple imputation was used to estimate participants' mean blood pressure. Mixed-effects models were used to evaluate associations between blood pressure and participant characteristics. Of 1 508 130 screenees 482 273 (32.0%) had never had a blood pressure measurement before and 513 337 (34.0%) had hypertension, of whom 58.7% were aware, and 54.7% were on antihypertensive medication. Of those on medication, 57.8% were controlled to <140/90 mm Hg, and 28.9% to <130/80 mm Hg. Of all those with hypertension, 31.7% were controlled to <140/90 mm Hg, and 350 825 (23.3%) participants had untreated or inadequately treated hypertension. Of those taking antihypertensive medication, half were taking only a single drug, and 25% reported using aspirin inappropriately. This survey is the largest ever synchronized and standardized contemporary compilation of global blood pressure data. This campaign is needed as a temporary substitute for systematic blood pressure screening in many countries worldwide.]]> Tue 19 Oct 2021 16:23:32 AEDT ]]> Hypertension and renin-angiotensin system blockers are not associated with expression of angiotensin-converting enzyme 2 (ACE2) in the kidney http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:15013 Mon 12 Apr 2021 15:22:09 AEST ]]> The prevalence of cardiovascular risk factors and cardiovascular disease among primary care patients in Poland : results from the LIPIDOGRAM2015 study http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:15692 80% had dyslipidaemia and <15% of patients were diagnosed with diabetes (DM). All of these disorders were more frequent in men. In 80% of patients the waist circumference exceed norm for the European population. Less than half of the patients were current smokers or had smoked in the past. Patients with CVD had significantly higher blood pressure and glucose levels but lower low density lipoprotein-cholesterol level. Conclusions: The prevalence of CVD and CV risk factors among patients in Poland is high. CVD is more common in men than in women. The most common CV risk factors are excess waist circumference, dyslipidaemia and HTN. Family physicians should conduct activities to prevent, diagnose early and treat CVD in the primary health care population. © 2021 Elsevier B.V. **Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Fadi Charchar” is provided in this record**]]> Mon 07 Feb 2022 15:14:21 AEDT ]]>