http://researchonline.federation.edu.au/vital/access/manager/Index ${session.getAttribute("locale")} 5 Involvement of human monogenic cardiomyopathy genes in experimental polygenic cardiac hypertrophy http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:13538 Wed 07 Apr 2021 14:01:40 AEST ]]> Renal Mechanisms of Association between Fibroblast Growth Factor 1 and Blood Pressure http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:10534 Wed 07 Apr 2021 13:55:52 AEST ]]> MicroRNAs mediate the cardioprotective effect of angiotensin-converting enzyme inhibition in acute kidney injury http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:10353 Wed 07 Apr 2021 13:55:42 AEST ]]> Runs of Homozygosity : Association with Coronary Artery Disease and Gene Expression in Monocytes and Macrophages http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:10162 Wed 07 Apr 2021 13:55:29 AEST ]]> The emerging role of non-coding RNA in essential hypertension and blood pressure regulation http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:10127 Wed 07 Apr 2021 13:55:26 AEST ]]> Acute exercise leads to regulation of Telomere-Associated genes and MicroRNA expression in immune Cells http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:5804 Wed 07 Apr 2021 13:45:22 AEST ]]> Urotensin-II system in genetic control of blood pressure and renal function http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:5740 Wed 07 Apr 2021 13:45:18 AEST ]]> Male-specific region of the y chromosome and cardiovascular risk phylogenetic analysis and gene expression studies http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:5099 Wed 07 Apr 2021 13:44:43 AEST ]]> Whole genome survey of copy number variation in the spontaneously hypertensive rat relationship to quantitative trait loci, gene expression, and blood pressure http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:2909 Wed 07 Apr 2021 13:33:56 AEST ]]> Kidney omics in hypertension: from statistical associations to biological mechanisms and clinical applications http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:17466 1000 common and rare genetic variants associated with BP and/or hypertension. The kidney is not only an organ of key relevance to BP regulation and the development of hypertension, but it also acts as the tissue mediator of genetic predisposition to hypertension. The identity of kidney genes, pathways, and related mechanisms underlying the genetic associations with BP has started to emerge through integration of genomics with kidney transcriptomics, epigenomics, and other omics as well as through applications of causal inference, such as Mendelian randomization. Single-cell methods further enabled mapping of BP-associated kidney genes to cell types, and in conjunction with other omics, started to illuminate the biological mechanisms underpinning associations of BP-associated genetic variants and kidney genes. Polygenic risk scores derived from genome-wide association studies and refined on kidney omics hold the promise of enhanced diagnostic prediction, whereas kidney omics-informed drug discovery is likely to contribute new therapeutic opportunities for hypertension and hypertension-mediated kidney damage. © 2022 International Society of Nephrology]]> Thu 23 Mar 2023 11:55:08 AEDT ]]> Human Y Chromosome Exerts Pleiotropic Effects on Susceptibility to Atherosclerosis http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:14223 Thu 19 May 2022 12:38:25 AEST ]]>