http://researchonline.federation.edu.au/vital/access/manager/Index ${session.getAttribute("locale")} 5 Inheritance of coronary artery disease in men : An analysis of the role of the y chromosome http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:4526 Wed 07 Apr 2021 13:43:59 AEST ]]> The epithelial sodium channel y-subunit gene and blood pressure : Family based association, renal gene expression, and physiological analyses http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:4524 Wed 07 Apr 2021 13:43:59 AEST ]]> Pathway analysis shows association between FGFBP1 and hypertension http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:4075 Wed 07 Apr 2021 13:43:24 AEST ]]> FGF21 signalling pathway and metabolic traits - genetic association analysis http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:3886 Wed 07 Apr 2021 13:34:55 AEST ]]> Fibroblast growth factor binding protein 1 gene (FGFBP1) and hypertension d from pathway analysis to renal glomerulus http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:3688 Wed 07 Apr 2021 13:34:42 AEST ]]> A common variant in low-density lipoprotein receptor-related protein 6 gene (LRP6) is associated with LDL-Cholesterol http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:2136 = 0.1) single nucleotide polymorphisms in LRP6 were genotyped in 703 individuals from 213 Polish pedigrees (Silesian Cardiovascular Study families). The family-based analysis revealed that the minor allele of rs10845493 clustered with elevated LDL-C in offspring more frequently than expected by chance (P=0.0053). The quantitative analysis restricted to subjects free of lipid-lowering treatment confirmed the association between rs10845493 and age-, sex-, and BMI-adjusted circulating levels of LDL-C in families as well as 2 additional populations - 218 unrelated subjects from Silesian Cardiovascular Study replication panel and 1138 individuals from Young Men Cardiovascular Association cohort (P=0.0268, P=0.0476, and P=0.0472, respectively). In the inverse variance weighted meta-analysis of the 3 populations each extra minor allele copy of rs10845493 was associated with 0.14 mmol/L increase in age-, sex-, and BMI-adjusted LDL-C (SE=0.05, P=0.0038). Conclusions-Common polymorphism in the gene underlying monogenic form of coronary artery disease impacts on risk of LDL-C elevation. (Arterioscler Thromb Vasc Biol. 2009;29:1316-1321.)]]> Wed 07 Apr 2021 13:33:12 AEST ]]> Systematic genetic analysis of fibroblast growth factor signalling pathway uncovers fibroblast growth factor binding protein 1 (FGFBP1) as a novel gene of essential hypertension http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:2137 Wed 07 Apr 2021 13:33:12 AEST ]]> Y chromosome haplogroup as a novel biological risk factor for coronary artery disease - The results of tracking paternal lineages in the west of Scotland primary prevention study (WOSCOPS) http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:2129 Wed 07 Apr 2021 13:33:11 AEST ]]> A common intronic variant in the gene underlying a rare monogenic form of coronary artery disease is associated with low-density lipoprotein cholesterol http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:2115 Wed 07 Apr 2021 13:33:10 AEST ]]> Common allelic variant in the gene underlying rare monogenic form of coronary artery disease cosegregates with elevated LDL cholesterol in families with high cardiovascular risk http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:890 Wed 07 Apr 2021 13:31:52 AEST ]]>