- Title
- A MicroRNA Guide for Clinicians and Basic Scientists : Background and Experimental Techniques
- Creator
- Bernardo, Bianca; Charchar, Fadi; Lin, Ruby; McMullen, Julie
- Date
- 2012
- Type
- Text; Journal article
- Identifier
- http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/59111
- Identifier
- vital:4519
- Identifier
-
https://doi.org/10.1016/j.hlc.2011.11.002
- Identifier
- ISSN:1443-9506
- Abstract
- MicroRNAs (miRNAs) are short non-coding RNA molecules that are approximately 22 nucleotides in length. In the last 10. years, miRNA research and discovery has advanced at a rapid rate. This review provides a brief overview of the discovery and biology of miRNAs, and summarises some of the experimental techniques used for isolation, detection, target prediction, and regulation of miRNAs. We also outline experimental workflows for investigators new to the field, and discuss the diagnostic and therapeutic application of miRNAs. © 2011 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ).
- Relation
- Heart Lung and Circulation Vol. 21, no. 3 (2012), p. 131-142
- Rights
- Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ)
- Rights
- This metadata is freely available under a CCO license
- Subject
- Biomarkers; Experimental Techniques; MicroRNAs; Research Tools; Therapeutics
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