- Gielen, Marij, Hageman, Geja, Antoniou, Evangelia, Nordfjall, Katarina, Mangino, Massimo, Balasubramanyam, Muthuswamy, De Meyer, Tim de, Hendricks, Audrey, Giltay, Erik, Hunt, Steven, Nettleton, Jennifer, Salpea, Klelia, Diaz, Vanessa, Farzaneh-Far, Ramin, Atzmon, Gil, Harris, Sarah, Hou, Lifang, Gilley, David, Hovatta, Iiris, Kark, Jeremy, Nassar, Hisham, Kurz, David, Mather, Karen, Willeit, Peter, Zheng, Yun-Ling, Pavanello, Sofia, Demerath, Ellen, Rode, Line, Bunout, Daniel, Steptoe, Andrew, Boardman, Lisa, Marti, Amelia, Needham, Belinda, Zheng, Wei, Ramsey-Goldman, Rosalind, Pellatt, Andrew, Kaprio, Jaakko, Hofmann, Jonathan, Gieger, Christian, Paolisso, Giuseppe, Hjelmborg, Jacob, Mirabello, Lisa, Seeman, Teresa, Wong, Jason, Van Der Harst, Pim, Broer, Linda, Kronenberg, Florian, Kollerits, Barbara, Strandberg, Timo, Eisenberg, Dan, Duggan, Catherine, Verhoeven, Josine, Schaakxs, Roxanne, Zannolli, Raffaela, Dos Reis, Rosana, Charchar, Fadi, Tomaszewski, Maciej, Mons, Ute, Demuth, Ilja, Molli, Andrea, Cheng, Guo, Krasnienkov, Dmytro, D'Antono, Bianca, Kasielski, Marek, McDonnell, Barry, Ebstein, Richard, Sundquist, Kristina, Pare, Guillaume, Chong, Michael, Zeegers, Maurice
- Authors: Gielen, Marij , Hageman, Geja , Antoniou, Evangelia , Nordfjall, Katarina , Mangino, Massimo , Balasubramanyam, Muthuswamy , De Meyer, Tim de , Hendricks, Audrey , Giltay, Erik , Hunt, Steven , Nettleton, Jennifer , Salpea, Klelia , Diaz, Vanessa , Farzaneh-Far, Ramin , Atzmon, Gil , Harris, Sarah , Hou, Lifang , Gilley, David , Hovatta, Iiris , Kark, Jeremy , Nassar, Hisham , Kurz, David , Mather, Karen , Willeit, Peter , Zheng, Yun-Ling , Pavanello, Sofia , Demerath, Ellen , Rode, Line , Bunout, Daniel , Steptoe, Andrew , Boardman, Lisa , Marti, Amelia , Needham, Belinda , Zheng, Wei , Ramsey-Goldman, Rosalind , Pellatt, Andrew , Kaprio, Jaakko , Hofmann, Jonathan , Gieger, Christian , Paolisso, Giuseppe , Hjelmborg, Jacob , Mirabello, Lisa , Seeman, Teresa , Wong, Jason , Van Der Harst, Pim , Broer, Linda , Kronenberg, Florian , Kollerits, Barbara , Strandberg, Timo , Eisenberg, Dan , Duggan, Catherine , Verhoeven, Josine , Schaakxs, Roxanne , Zannolli, Raffaela , Dos Reis, Rosana , Charchar, Fadi , Tomaszewski, Maciej , Mons, Ute , Demuth, Ilja , Molli, Andrea , Cheng, Guo , Krasnienkov, Dmytro , D'Antono, Bianca , Kasielski, Marek , McDonnell, Barry , Ebstein, Richard , Sundquist, Kristina , Pare, Guillaume , Chong, Michael , Zeegers, Maurice
- Date: 2018
- Type: Text , Journal article
- Relation: American Journal of Clinical Nutrition Vol. 108, no. 3 (2018), p. 453-475
- Relation: http://purl.org/au-research/grants/nhmrc/1123472
- Full Text: false
- Reviewed:
- Description: Background: Even before the onset of age-related diseases, obesity might be a contributing factor to the cumulative burden of oxidative stress and chronic inflammation throughout the life course. Obesity may therefore contribute to accelerated shortening of telomeres. Consequently, obese persons are more likely to have shorter telomeres, but the association between body mass index (BMI) and leukocyte telomere length (TL) might differ across the life span and between ethnicities and sexes. Objective: A collaborative cross-sectionalmeta-analysis of observational studies was conducted to investigate the associations between BMI and TL across the life span. Design: Eighty-seven distinct study samples were included in the meta-analysis capturing data from 146,114 individuals. Studyspecific age- and sex-adjusted regression coefficients were combined by using a random-effects model in which absolute [base pairs (bp)] and relative telomere to single-copy gene ratio (T/S ratio) TLs were regressed against BMI. Stratified analysis was performed by 3 age categories ("young": 18-60 y; "middle": 61-75 y; and "old": >75 y), sex, and ethnicity. Results: Each unit increase in BMI corresponded to a-3.99 bp (95% CI: -5.17, -2.81 bp) difference in TL in the total pooled sample; among young adults, each unit increase in BMI corresponded to a -7.67 bp (95% CI:-10.03,-5.31 bp) difference. Each unit increase in BMI corresponded to a -1.58 × 10-3 unit T/S ratio (0.16% decrease; 95% CI: -2.14 × 10-3, -1.01 × 10-3) difference in ageand sex-adjusted relative TL in the total pooled sample; among young adults, each unit increase in BMI corresponded to a -2.58 × 10-3 unit T/S ratio (0.26% decrease; 95% CI: -3.92 × 10-3, -1.25 × 10-3). The associations were predominantly for the white pooled population. No sex differences were observed. Conclusions: A higher BMI is associated with shorter telomeres, especially in younger individuals. The presently observed difference is not negligible. Meta-analyses of longitudinal studies evaluating change in body weight alongside change in TL arewarranted.
- Chen, Jiarui, Cross, Wendy, Plummer, Virginia, Lam, Louisa, Tang, Siyuan
- Authors: Chen, Jiarui , Cross, Wendy , Plummer, Virginia , Lam, Louisa , Tang, Siyuan
- Date: 2019
- Type: Text , Journal article , Review
- Relation: Women and Birth Vol. 32, no. 6 (Dec 2019), p. 487-492
- Full Text: false
- Reviewed:
- Description: Background: As the number of immigrants grows, the health of Chinese immigrant women, especially their perinatal health, has gradually attracted public attention. Our review has two main purposes. First, estimate the prevalence of postpartum depressive symptoms in Chinese immigrant women, and then determine risk factors for postpartum depressive symptoms among these women. Methods: The following databases: MEDLINE, Embase, Scopus, Web of Science, PsycINFO and PubMed were used in literature search from their commencements until November 21st 2017. The Joanna Briggs Institute (JBI) Critical Appraisal instruments were used to evaluate the quality of the article. Four studies met the inclusion criteria, contributed to our review and meta-analysis. Result: The prevalence of postpartum depression is high in Chinese immigrant women. Risk factors for postpartum depression in Chinese immigrant women were defined as lack of social support, unstable economic status, and acculturation. Conclusion: There have been few studies on postpartum depression among Chinese immigrant women. Existing studies have shown a high prevalence of postpartum depression in Chinese immigrant women. Moreover, there is an urgent need for studies on postpartum depression among Chinese immigrant women informing better understanding, programs of care and improving the perinatal health status of Chinese immigrant women. (C) 2018 Australian College of Midwives. Published by Elsevier Ltd. All rights reserved.
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