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Analysis of the impact of sex and age on the variation in the prevalence of antinuclear autoantibodies in Polish population : a nationwide observational, cross-sectional study

- Krzemie, Kasperczyk, Sławomir, Banach, Maciejc, Kasperczyk, Aleksandra, Dobrakowski, Michał, Tomasik, Tomasz, Windak, Adam, Mastej, Mirosław, Catapano, Alberico, Ray, Kausik, Mikhailidis, Dimitri, Toth, Peter, Howard, George, Lip, Gregory, Tomaszewski, Macie, Charchar, Fadi, Sattar, Naveed, Williams, Bryan, MacDonald, Thomas, Penson, Peter, J, Al-Shaer B, Andrusewicz W., Anusz-Gaszewska E., B, Balawajder P., Bańka G., Barańska-Skubisz E., Przyczyna, B., Bartkowiak S.

Infographic consensus recommendations on the classification, definition and diagnostic criteria of hip-related pain in young and middle-aged active adults from the International Hip-related Pain Research Network, Zurich 2018

- Reiman, Michael, Agricola, Rintje, Kemp, Joanne, Heerey, Joshua, Weir, Adam, Van Klij, Pim, Kassarjian, Ara, Mosler, Andrea, Ageberg, Eva, Hölmich, Perj, WArholm, Kristian, Griffin, Damian, Mayes, Suec, Khan, Karim, Crossley, Kay, Bizzini, Mario, Bloom, Nancy, Casartelli, Nicola, Diamond, Laura, Di Stasi, Stephanieu, Drew, Michael, Friedman, Daniel, Freke, Matthew, Glyn-Jones, Sionz, Gojanovic, Borisaa, Harris-Hayes, Marcie, Hunt, Michael, Impellizzeri, Franco, Ishøi, Lasseae;, Jones, Denise

Training load and recovery during a pre-olympic season in professional rhythmic gymnasts

- Debien, Paula, Miloski, Bernardo, Werneck, Francisco, Timoteo, Thiago, Ferezin, Camila, Filho, Mauricio, Gabbett, Tim

  • Authors: Debien, Paula , Miloski, Bernardo , Werneck, Francisco , Timoteo, Thiago , Ferezin, Camila , Filho, Mauricio , Gabbett, Tim
  • Date: 2020
  • Type: Text , Journal article
  • Relation: Journal of Athletic Training Vol. 55, no. 9 (2020), p. 977-983
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  • Description: Context: Rhythmic gymnastics requires a high level of complexity and perfection of technical gestures, associated with well-developed physical and artistic capacities. The training-load and recovery profiles of rhythmic gymnasts across a season are unknown. Objective: To analyze the training load and recovery of professional rhythmic gymnasts during 1 season. Design: Cohort study. Setting: Brazilian National Training Center of Rhythmic Gymnastics and competition facilities. Patients or Other Participants: Eight gymnasts from the Brazilian national senior rhythmic gymnastics group. Main Outcome Measure(s): Session rating of perceived exertion (session-RPE) and total quality recovery (TQR) scores were collected daily for 43 weeks. We obtained the session-RPE after each session and TQR score before the first session of the day. Performances during 5 competitions were also recorded. The season was divided into 8 periods. Total weekly internal training load (wITL), training intensity, frequency, duration, recovery, and acute: chronic workload ratio were calculated for analysis. Results: The season mean wITL was 10 381 6 4894 arbitrary units, mean session-RPE score was 5.0 6 1.6, and mean TQR score was 12.8 6 1.3. The gymnasts trained an average of 8.7 6 2.9 sessions per week, with a mean duration of 219 6 36 minutes. Each competitive period showed increased wITL compared with the previous period. Training-load variables (wITL and session-RPE) and recovery were inversely correlated. Gymnasts were poorly recovered (TQR, 13) during 50.9% of the season (n ¼ 167 times), especially during competitive weeks. Spikes in load (acute: chronic workload ratio ≥ 1.5) occurred across 18.1% of the season (n ¼ 55 times). Conclusions: The training-load variables and recovery changed throughout a professional rhythmic gymnastics group season, mainly during competitive periods. The correct distribution of training load is critical to ensure that gymnasts are entering competitions in a recovered state. © by the National Athletic Trainers' Association, Inc www.natajournals.org

Influence of workload and recovery on injuries in elite male volleyball players

- Timoteo, Thiago, Debien, Paula, Miloski, Bernardo, Werneck, Francisco, Gabbett, Tim, Bara Filho, Mauricio

  • Authors: Timoteo, Thiago , Debien, Paula , Miloski, Bernardo , Werneck, Francisco , Gabbett, Tim , Bara Filho, Mauricio
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Journal of strength and conditioning research Vol. 35, no. 3 (2021), p. 791-796
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  • Description: ABSTRACT: Timoteo, TF, Debien, PB, Miloski, B, Werneck, FZ, Gabbett, T, and Filho, MGb. Influence of workload and recovery on injuries in elite male volleyball players. J Strength Cond Res 35(3): 791-796, 2021-The aim of this study was to investigate the influence of workload and recovery on injury rates in elite male volleyball players. Data were collected from 14 male professional volleyball players over a 27-week season. Workloads were monitored daily using the session rating of perceived exertion, and recovery status was appraised using the Total Quality Recovery (TQR) scale. The players were exposed to 4,573.31 hours (h) of training and games with an overall injury incidence of 13.99 per 1,000 hours. Overuse accounted for 83% (11.58 injuries/1,000 hours) and trauma accounted for 17% (2.40 injuries per 1,000 hours) of all injuries. There was a higher incidence of injuries (p = 0.003), higher weekly workload (p = 0.008), and acute:chronic workload ratio (ACWR) (p < 0.001) in the pre-season compared with the competitive period. Healthy players had lower ACWR (p = 0.002) compared with the injured players. The TQR was higher for the healthy group compared with the injured group (p < 0.001). The greater odds of injury was related to higher ACWR (risk factor) (p = 0.014) and lower TQR values (p = 0.004) (protection factor). Athlete's workloads and the state of recovery may be related to injuries in volleyball. The results presented in this study emphasize the importance of controlling these variables in professional volleyball teams to prevent injuries. Copyright © 2018 National Strength and Conditioning Association.

Association between cognitive dysfunction and nocturnal peaks of blood pressure estimated from pulse transit time in obstructive sleep apnoea

- Alomri, Ridwan, Kennedy, Gerard, Wali, Siraj, Alhejaili, Faris, Zelko, Matthew, Robinson, Stephen

  • Authors: Alomri, Ridwan , Kennedy, Gerard , Wali, Siraj , Alhejaili, Faris , Zelko, Matthew , Robinson, Stephen
  • Date: 2022
  • Type: Text , Journal article
  • Relation: Sleep Medicine Vol. 90, no. (2022), p. 185-191
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  • Description: Background: Obstructive sleep apnoea (OSA) is characterised by recurrent episodes of partial or complete cessation of breathing during sleep and an increased effort to breathe. Patients with untreated OSA exhibit cognitive impairment that is only partly accounted for by hypoxia and sleep disruption, suggesting that other factors remain to be identified. OSA can involve repeated spikes of nocturnal blood pressure because of increased activity of the sympathetic nervous system during sleep. While high resting blood pressure is associated with cognitive dysfunction, it is not yet known whether peaks in nocturnal blood pressure are associated with cognitive impairment in OSA. Methods: A cohort of patients participated in overnight polysomnographic studies at a major sleep laboratory to investigate whether nocturnal elevations in blood pressure are associated with cognitive dysfunction in OSA. Nocturnal pulse transit time was measured as a surrogate for arterial blood pressure during sleep. Results: Of the 75 patients, 12 had no obstructive sleep apnoea, 26 had mild OSA, 18 moderate, and 19 severe OSA. The results revealed that systolic blood pressure peaks were associated with OSA severity, while diastolic blood pressure peaks were not. Peaks of nocturnal systolic blood pressure were independently associated with poorer performance on a test of visuospatial function, but not with impairments on tests of sustained attention, reaction time or autobiographical memory. Conclusion: The present findings indicate nocturnal peaks of systolic blood pressure that are substantially higher than normal daytime values may contribute to visuospatial dysfunction in OSA. © 2022 Elsevier B.V.

The role of internet gaming in the association between anxiety and depression : a preliminary cross-sectional study

- Stavropoulos, Vasileios, Vassallo, Jeremy, Burleigh, Tyrone, Gomez, Rapson, Colder Carras, Michelle

  • Authors: Stavropoulos, Vasileios , Vassallo, Jeremy , Burleigh, Tyrone , Gomez, Rapson , Colder Carras, Michelle
  • Date: 2022
  • Type: Text , Journal article
  • Relation: Asia-Pacific Psychiatry Vol. 14, no. 2 (2022), p.
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  • Description: Background: Disordered Internet gaming is thought to be perpetuated by one's need to escape their real-life distress or mental health symptoms, which may in turn generate depressive feelings. Nevertheless, moderate engagement with Internet games has also been suggested to provide relief, thus improving one's mood. This study aspires to clarify the contribution of Internet gaming and gender in the association between anxiety and depression. Methods: A large sample of Internet gamers (N = 964) were recruited online. Disordered Internet gaming was assessed with the Internet Gaming Disorder Scale, 9 Items Short Form (IGD9S-SF). Anxiety and depression symptoms were assessed using the Depression, Anxiety and Stress Scale, 21 items (DASS-21). Results: Regression, moderation and moderated moderation analyses accounting for the effects of gender on the relationship between disordered gaming, anxiety, and depression found a significant effect for anxiety symptoms on depression symptoms and a significant interaction between anxiety and Internet gaming disorder on depression symptoms. Findings support the theory that although anxious gamers bear a higher depression risk, this is buffered with lower and exacerbated with higher disordered gaming symptoms. Conclusion: Findings suggest a dual role of Internet gaming in the association between anxiety and depression, depending on the intensity of one's disordered gaming symptoms. Depression prevention and intervention protocols should be optimized by considering the effects of Internet gaming among anxious gamers by focusing on the intensity of a gamer's involvement and any gaming disorder symptoms. Further research should include clinical samples to better understand this interaction. © 2021 John Wiley & Sons Australia, Ltd.

Network analyses of internet gaming disorder symptoms and their links with different types of motivation

- Gomez, Rapson, Stavropoulos, Vasileios, Tullett-Prado, Deon, Schivinski, Bruno, Chen, Wai

  • Authors: Gomez, Rapson , Stavropoulos, Vasileios , Tullett-Prado, Deon , Schivinski, Bruno , Chen, Wai
  • Date: 2022
  • Type: Text , Journal article
  • Relation: BMC Psychiatry Vol. 22, no. 1 (2022), p.
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  • Description: The study used regularized partial correlation network analysis (EBICglasso) to examine the structure of DSM-5 internet gaming disorder (IGD) symptoms (network 1); and the associations of the IGD symptoms in the network with different types of motivation as defined in the self-determination theory i.e., intrinsic motivation (engaging in an activity for something unrelated to the activity), identified regulation (engaging in the activity because it aligns with one’s values and/or goals), external regulation (engagement in activity being driven by external rewards and/or approval), and amotivation (engaging in an activity without often understanding why) (network 2). Participants were 968 adults from the general community. They completed self-rating questionnaires covering IGD symptoms and different types of motivation. The findings for network 1 showed mostly positive connections between the symptoms within the IGD network. The most central symptom was loss of control, followed by continuation, withdrawal symptoms, and tolerance. In general, these symptoms were more strongly connected with each other than with the rest of the IGD symptoms. The findings for network 2 showed that the different types of motivation were connected differently with the different IGD symptoms. For instance, the likeliest motivation for the preoccupation and escape symptoms is intrinsic motivation, and for negative consequences, it is low identified regulation. Overall, the findings showed a novel understanding of the structure of the IGD symptoms, and the motivations underlying them. The clinical implications of the findings for assessment and treatment of IGD are discussed. © 2022, The Author(s).

Expression of TIMPs and MMPs in ovarian tumors, ascites, ascites-derived cells, and cancer cell lines : characteristic modulatory response before and after chemotherapy treatment

- Escalona, Ruth, Kannourakis, George, Findlay, Jock, Ahmed, Nuzhat

  • Authors: Escalona, Ruth , Kannourakis, George , Findlay, Jock , Ahmed, Nuzhat
  • Date: 2022
  • Type: Text , Journal article
  • Relation: Frontiers in Oncology Vol. 11, no. (2022), p.
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  • Description: Background: The tissue inhibitors of metalloproteinase (TIMPs) and their associated metalloproteinase (MMPs) are essential regulators of tissue homeostasis and are essential for cancer progression. This study analyzed the expression of TIMP-1,-2,-3 and the associated MMPs (MMP-2,-9,-11,-14) in different Stages, Grades and World Health Organization (WHO) classifications of serous ovarian tumors, ascites, ascites-derived cells from chemo-naïve (CN) and relapsed (CR) patients, and in ovarian cancer cell lines. The status of TIMPs and associated MMPs in response to chemotherapy treatment was assessed in cancer cell lines; TCGA data was interrogated to gauge TIMPs and associated MMPs as prognostic and platinum-response indicators. Methods: The levels of TIMP-1, -2 and -3 were assessed by immunohistochemistry. The mRNA expression of TIMPs and MMPs was quantified by real time PCR (qRT-PCR). The chemosensitivity (IC50 values) to Cisplatin or Paclitaxel in cell lines was evaluated by MTT assay. The levels of TIMPs in ascites and cell lysates were analyzed by an ELISA assay. Results: The expression of TIMP-2 was significantly upregulated in Type 2 compared to Type 1 tumors and normal/benign ovarian tissues. TIMP-3 expression was significantly enhanced in Stage III, Grade 3 and Type 2 tumors compared to normal/benign ovarian tissues. The mRNA expression of MMP-9,-11 and -14 was significantly upregulated in Stage IV compared to normal/benign ovarian tissues. The expression of TIMP-1 was highest, followed by TIMP-2 and then TIMP-3 in CN ascites. At the cellular level, TIMP-2 mRNA expression was significantly higher in CN compared to CR epithelial cells in patients. The expression of TIMP-1 and -2, MMPs and cancer stem cells (CSCs) were upregulated in response to chemotherapy treatments in cancer cell lines. Interrogation of the TCGA dataset suggests shifts in platinum responses in patients consistent with genetic alterations in TIMP-2, -3 and MMP-2, -11 genes in tumors; and decreased overall survival (OS) and progression-free survival (PFS) in patients with altered MMP-14 genes. Conclusions: TIMPs and related MMPs are differentially expressed in serous ovarian tumors, ascites, ascites-derived cells and ovarian cancer cell lines. Chemotherapy treatment modulates expression of TIMPs and MMPs in association with increased expression of genes related to cancer stem cells. Copyright © 2022 Escalona, Kannourakis, Findlay and Ahmed.

The impact of COVID-19 restrictions on Australians' frequency and duration of participation in different types of sport and physical activity

- Eime, Rochelle, Harvey, Jack, Charity, Melanie, Pankowiak, Aurelie, Westerbeek, Hans

  • Authors: Eime, Rochelle , Harvey, Jack , Charity, Melanie , Pankowiak, Aurelie , Westerbeek, Hans
  • Date: 2022
  • Type: Text , Journal article
  • Relation: BMC Sports Science, Medicine and Rehabilitation Vol. 14, no. 1 (2022), p.
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  • Description: Background: Sports management and public health physical activity stakeholders need to understand changing patterns of participation to inform the development of sport and physical activity opportunities and strategies. This study investigated changes in the frequency and duration of participation in sport and physical activity in Australia from pre-COVID-19 to during-COVID-19, broken down by the specific type of activity and by gender, age and region. Methods: During the first pandemic restrictions and lockdowns in Australia in May–June 2020, 6140 survey respondents provided information about the types, frequency and duration of the sport and physical activity they participated in prior to and during COVID-19 restrictions. Differences between mean values were analyzed. Results: The greatest decline in participation during COVID-19 was in team sports, and the decline was greater for men than for women. Conclusion: How will sport respond to getting these men back in the game, and women back from home-based yoga and Pilates? © 2022, The Author(s).

A qualitative exploration of the impact of knowledge and perceptions about hypertension in medication adherence in Middle Eastern refugees and migrants

- Shahin, Wejdan, Kennedy, Gerard, Stupans, Ieva

  • Authors: Shahin, Wejdan , Kennedy, Gerard , Stupans, Ieva
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Exploratory Research in Clinical and Social Pharmacy Vol. 3, no. (2021), p. 100038-100038
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  • Description: Knowledge and perceptions about chronic disease and medications play a crucial role in determining long-term treatment adherence to diseases such as hypertension. Exploring in depth the barriers and enablers to medication adherence in specific population subgroups such as Middle Eastern refugees and migrants in Australia is important. This may provide a better understanding of each of these groups' beliefs and knowledge and suggest strategies and interventions to improve medication adherence. This study aimed to understand Middle Eastern refugees' and migrants' experiences, perceptions, and knowledge about hypertension and to explore factors affecting medication adherence. In this study 15 participants who identified themselves as Middle Eastern refugees and migrants in Australia and had been diagnosed with hypertension were interviewed (migrants = 5, refugees =10) using semi-structured interviews. Recorded interviews were analysed using a thematic analysis framework and the findings were reported according to consolidated criteria for reporting qualitative research. Three key themes emerged from the interview analysis: (1) dealing with the illness in terms of understanding the symptoms and causes, self-managing of high blood pressure, and coping and acquaintance with the illness (2) beliefs, practices around medication adherence and the barriers and facilitators to taking medications regularly and (3) healthcare encounters represented by participants trust in healthcare providers. Differences were found between refugees and migrants relating to the understanding, control, and coping with hypertension, beliefs about medications, trust of healthcare providers, and taking medications as prescribed. There were also differences in the social context of the two groups. Understanding the factors that prevent adherence to hypertension in Middle Eastern refugees addressed the gap in the literature regarding refugees' beliefs and medication adherence. Future studies are recommended to assess the improvement in medication adherence in refugees by modifying their beliefs, attitude, and knowledge about medications and illness. In addition, healthcare providers should consider the differences between Middle Eastern refugees and migrants when providing the health advice that targets each of these population independently to ultimately improve their overall health and adherence to medications. Erratum: The publisher regrets that the section below was accidentally anonymized in the original published version of this article: “Ethical approval was obtained from (redacted) 60–19/22299”. This section should read: “Ethical approval was obtained from RMIT University Ethics Committee 60–19/22299”. The publisher would like to apologise for any inconvenience caused.

Pediatric emergency asthma presentations in Southwest Victoria : a retrospective cross-sectional study 2017 to 2020

- Terry, Daniel, Peck, Blake, Kloot, Kloot, Hutchins, Toinette

  • Authors: Terry, Daniel , Peck, Blake , Kloot, Kloot , Hutchins, Toinette
  • Date: 2022
  • Type: Text , Journal article
  • Relation: Journal of Asthma Vol. 59, no. 2 (2022), p. 264-272
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  • Description: Objectives: Australia has one of the highest prevalence of asthma globally, and accessible emergency asthma presentation data remains vital, however, is currently underreported in regional and rural areas. Utilizing the Rural Acute Hospital Data Register (RAHDaR) which includes previously non-reported data, the aim of the study is to provide a more accurate understanding of asthma emergency presentation events, while investigating the factors associated with these presentations. Methods: A retrospective cross-sectional study collected de-identified emergency asthma presentation data from nine health services in regional Victoria for children aged 0 to 14 years between 2017 and 2020. Demographic and presentation data were collated along with government datasets. Asthma emergency presentations incidence rates and predictor variables were analyzed using hierarchical multiple regression after adjusting for smoking and sex. Significance was determined at p < 0.05. Results: Of the 1090 emergency asthma presentations, n = 369 occurred at health services who did not previously report data. This represents a 33.86% increase in our understanding of emergency asthma presentations and demonstrating a rate of 16.06 presentations per 1000 children per year. Key factors such as age, population density, and private health insurance were associated with asthma emergency presentation events among both sexes, while socioeconomic status and rurality were not predictive. Conclusions: Although some findings are consistent with current research, the study highlights previously unrecognized specific factors that are predictive of asthma among 0–14-year-old children. These findings provide more accurate insights for healthcare workers and policymakers as they seek to support people with asthma and accurately address health inequities. © 2020 Taylor & Francis Group, LLC.

Prevalence and correlates of diabetes distress and depressive symptoms among individuals with type-2 diabetes mellitus during Ramadan fasting : a cross-sectional study in Bangladesh amid the COVID-19

- Sultana, Mst Sadiaa, Islam, Md Saiful, Sayeed, Abu, Potenza, Marc, Sikder, Md Tajuddin, Rahman, Muhammad Aziz, Koly, Kamrun

  • Authors: Sultana, Mst Sadiaa , Islam, Md Saiful , Sayeed, Abu , Potenza, Marc , Sikder, Md Tajuddin , Rahman, Muhammad Aziz , Koly, Kamrun
  • Date: 2022
  • Type: Text , Journal article
  • Relation: Diabetes Research and Clinical Practice Vol. 185, no. (2022), p.
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  • Description: Aims: Psychological concerns relating to “diabetes distress” (DD) and depressive symptoms (DS) in individuals with type-2 diabetes mellitus (T2DM) may negatively impact adherence to medical treatments and overall mental health. Thus, this study was undertaken to investigate DS and DD in relation to fasting during the month of Ramadan. Methods: A cross-sectional survey was conducted among 735 patients with T2DM in 2021. DD and DS were measured by the Problem Areas in Diabetes scale and Patient Health Questionnaire-9, respectively. Logistic regression and correlation analyses were executed. Results: More than one-third of the participants (41.2%) had DD and DS (36.9%). DS was significantly higher in participants who did not fast (p = 0.027). Participants who had higher dietary diversity were less likely to have DD (p = 0.004) and DS (p = 0.001). Females (AOR = 1.89, 95% CI: 1.25–2.85) and those who lived alone (AOR = 1.89, 95% CI: 1.25–2.85) were more likely to have DS. Participants with diabetes-related complications were more likely to experience DS (AOR = 2.17; 95% CI: 1.5–3.13) and DD (AOR = 3.46; 95% CI: 2.42–4.95). DD was also associated with being younger (p = 0.003), having hypertension (p = 0.030), having heart disease (p = 0.012), and taking insulin (p = 0.010). Conclusions: Individuals with T2DM who were not fasting experienced more mental health concerns. Psychosocial support and other interventions from health professionals should be examined and empirical interventions should be implemented to promote the mental health and well-being of individuals with T2DM. © 2022 Elsevier B.V.

Indicators of job quality in the Australian aged care workforce : a scoping review

- Carnemolla, Phillippa, Taylor, Philip, Gringart, Eyal, Adams, Claire

  • Authors: Carnemolla, Phillippa , Taylor, Philip , Gringart, Eyal , Adams, Claire
  • Date: 2022
  • Type: Text , Journal article , Review
  • Relation: Australasian Journal on Ageing Vol. 41, no. 2 (2022), p. e94-e102
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  • Description: Objective: As governments grapple with ageing populations, there is a need to understand more about the aged care workforce and how it is managed. Methods: We undertook a scoping review according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidelines. Scopus and PubMed were used to identify papers published between 2010 and 2020. We mapped the breadth and scale of the evidence base according to the QuInnE indicators of job quality. Results: Out of 642 titles and abstracts that were screened, 122 were selected. Outcomes were measured across a range of domains, including wages, employment quality, education and training, working conditions, work/life balance and consultative participation and collective representation. These were distributed unevenly, revealing evidence gaps. Conclusions: We identified significant knowledge gaps regarding Australia's aged care workforce at a time when the sector is coming under fresh scrutiny and projections indicate that it will face critical labour shortfalls going forward. © 2021 AJA Inc.

Assessment of emergency department staff awareness, access and utilisation of advance care directives and goals of care : a cross-sectional survey

- Osman, Abdi, Howell, Jocelyn, Smithies, Lisa, Wilson, Damian, Lam, Louisa, Moran, Juli, Jones, Daryl, Taylor, David

  • Authors: Osman, Abdi , Howell, Jocelyn , Smithies, Lisa , Wilson, Damian , Lam, Louisa , Moran, Juli , Jones, Daryl , Taylor, David
  • Date: 2022
  • Type: Text , Journal article
  • Relation: Australasian Emergency Care Vol. 25, no. 3 (2022), p. 235-240
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  • Description: Background: Emergency department staff awareness, access and implementation of advance care directives and goals of care documents and the related patient consent processes are important but not well understood. Methods: A cross-sectional survey using purposive sampling was undertaken at a tertiary hospital's Emergency Department from 15th March to 26th April 2021. Participants were recruited through online platforms. Pre-validated questionnaires were distributed by email or as QR codes on bulletin boards. Data collected included staff: demographics, knowledge, access and implementation of advance care directives and goals of care documentation. Results: One hundred thirty-four (28%) of 476 targeted participants responded with nursing forming largest group. Results showed that previous attendance of advance care planning education was low at 20%. Familiarity with advance care directive documentations was only 19% while with goals of care document was average. 61 (48%) respondents reported ease of accessing electronic documents and 21 (19%) reported feeling very comfortable discussing and setting goals of care with patients (p = <0.01). Conclusions: Staff awareness of advance care directive was poor, while awareness of goals of care was average. There was no association between advance care directives awareness and staff age group, gender, length of: - professional practice, practice at the study site. © 2021

Countermovement jump variables not tensiomyography can distinguish between sprint and endurance focused track cyclists

- Lewis, Mitchell, Young, Warren, Knapstein, Luke, Lavender, Andrew, Talpey, Scott

  • Authors: Lewis, Mitchell , Young, Warren , Knapstein, Luke , Lavender, Andrew , Talpey, Scott
  • Date: 2022
  • Type: Text , Journal article
  • Relation: Biology of Sport Vol. 39, no. 1 (2022), p. 67-72
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  • Description: This study investigated the reliability and discriminative ability of tensiomyography and countermovement jump variables as measures of a muscles contractile properties in a cohort of elite endurance and sprint track cyclists. Tensiomyography was performed on the vastus lateralis (VL) and rectus femoris (RF) muscles in sprint track cyclists (N = 8) and endurance track cyclists (N = 8). Additionally, the participants completed a countermovement jump on a force plate. Tensiomyography measurements obtained from the RF displayed greater reliability (ICC = 0.879–0.997) than VL (ICC = 0.746–0.970). Radial muscle belly displacement (Dm), contraction time (Tc) and delay time (Td) demonstrated the most reliable TMG measurements. Only two variables displayed acceptable coefficient of variation (RF Td = 8.89, VL Td = 6.88), other variables presented as unacceptable. The TMG variables were unable to discriminate between endurance and sprint track cyclists whilst the CMJ variables could. Due to the high variability in measurements and its inability to distinguish between sprint and endurance based track cyclists TMG should be used cautiously in this athlete population and if available the CMJ is a more appropriate assessment of leg muscle function. © 2022 Institute of Sport. All rights reserved.

Deficiency of MicroRNA-181a results in transcriptome-wide cell-specific changes in the kidney and increases blood pressure

- Paterson, Madeleine, Jackson, Kristy, Dona, Malathi, Farrugia, Gabriella, Visniauskas, Bruna, Watson, Anna, Johnson, Chad, Prieto, Minolfa, Evans, Roger, Charchar, Fadi, Pinto, Alexander, Marques, Francine, Head, Geoffrey

  • Authors: Paterson, Madeleine , Jackson, Kristy , Dona, Malathi , Farrugia, Gabriella , Visniauskas, Bruna , Watson, Anna , Johnson, Chad , Prieto, Minolfa , Evans, Roger , Charchar, Fadi , Pinto, Alexander , Marques, Francine , Head, Geoffrey
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Hypertension Vol. 78, no. 5 (Nov 2021), p. 1322-1334
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  • Description: MicroRNA miR-181a is downregulated in the kidneys of hypertensive patients and hypertensive mice. In vitro, miR-181a is a posttranslational inhibitor of renin expression, but pleiotropic mechanisms by which miR-181a may influence blood pressure (BP) are unknown. Here, we determined whether deletion of miR-181a/b-1 in vivo changes BP and the molecular mechanisms involved at the single-cell level. We developed a KO (knockout) mouse model lacking miR-181a/b-1 genes using CRISPR/Cas9 technology. Radiotelemetry probes were implanted in 12-week-old C57BL/6J WT (wild type) and miR-181a/b-1 KO mice. Systolic and diastolic BP were 4- to 5-mm Hg higher in KO compared with WT mice over 24 hours (P<0.01). Compared with WT mice, renal renin was higher in the juxtaglomerular cells of KO mice. BP was similar in WT mice on a high- (3.1%) versus low- (0.3%) sodium diet (+0.4 +/- 0.8 mm Hg), but KO mice showed salt sensitivity (+3.3 +/- 0.8 mm Hg; P<0.001). Since microRNAs can target several mRNAs simultaneously, we performed single-nuclei RNA sequencing in 6699 renal cells. We identified 12 distinct types of renal cells, all of which had genes that were dysregulated. This included genes involved in renal fibrosis and inflammation such as Stat4, Col4a1, Cd81, Flt3l, Cxcl16, and Smad4. We observed upregulation of pathways related to the immune system, inflammatory response, reactive oxygen species, and nerve development, consistent with higher tyrosine hydroxylase in the kidney. In conclusion, downregulation of the miR-181a gene led to increased BP and salt sensitivity in mice. This is likely due to an increase in renin expression in juxtaglomerular cells, as well as microRNA-driven pleiotropic effects impacting renal pathways associated with hypertension.

Match high-speed running distances are often suppressed after return from hamstring strain injury in professional footballers

- Whiteley, Rodney, Massey, Andrew, Gabbett, Tim, Blanch, Peter, Cameron, Matthew, Conlan, Greta, Ford, Matthew, Williams, Morgan

  • Authors: Whiteley, Rodney , Massey, Andrew , Gabbett, Tim , Blanch, Peter , Cameron, Matthew , Conlan, Greta , Ford, Matthew , Williams, Morgan
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Sports Health Vol. 13, no. 3 (2021), p. 290-295
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  • Description: Background: High-speed running is commonly implicated in the genesis of hamstring injury. The success of hamstring injury management is typically quantified by the duration of time loss or reinjury rate. These metrics do not consider any loss in performance after returning to play from hamstring injury. It is not known to what extent high-speed running is altered on return to play after such injury. Hypothesis: Match high-speed running distance will change after returning from hamstring injury. Study Design: Non-randomized cohort. Level of Evidence: Level 3. Methods: Match high-speed running distance in highest level professional football (soccer, Rugby League, Rugby Union, and Australian Rules) were examined for a minimum of 5 games prior and subsequent to hamstring strain injury for individual differences using a linear regression models approach. A total of 22 injuries in 15 players were available for analysis. Results: Preinjury cumulative high-speed running distances were strongly correlated for each individual (r2 = 0.92-1.0 P < 0.0001). Pre- and postinjury high-speed running data were available for a median of 15 matches (range, 6-15). Variance from the preinjury high-speed running distance was significantly less (P = 0.0005) than the post injury values suggesting a suppression of high-speed running distance after returning from injury. On return to play, 7 of the 15 players showed a sustained absolute reduction in preinjury high-speed running distance, 7 showed no change, and 1 player (only) showed an increase. Analysis of subsequent (second and third injury) return to play showed no differences to return from the index injury. Conclusion: Return to play was not associated with return to high-speed running performance for nearly half of the players examined, although the same number showed no difference. Persisting deficits in match high-speed running may exist for many players after hamstring strain injury. Clinical Relevance: Returning to play does not mean returning to (high-speed running) performance for nearly half of the high-level professional football players examined in this study. This suggests that successful return to play metrics should be expanded from simple time taken and recurrence to include performance.

Competencies and training of health professionals engaged in health coaching : a systematic review

- Singh, Harjit, Kennedy, Gerard, Stupans, Ieva

  • Authors: Singh, Harjit , Kennedy, Gerard , Stupans, Ieva
  • Date: 2022
  • Type: Text , Journal article
  • Relation: Chronic Illness Vol. 18, no. 1 (2022), p. 58-85
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  • Description: Objective: A systematic review was undertaken in order to evaluate the competencies of primary healthcare professionals who are engaged with health coaching patients with chronic health conditions. Methods: The databases CINHAL, EMBASE, PubMed, PsychINFO and SCOPUS were searched to identify peer reviewed papers referring to competencies of health professionals engaged in health coaching. Results: Nine key competencies that health professionals met and which resulted in successful patient outcomes from health coaching were identified. Comparisons of the core health coaching competencies to the competencies for coaches established by the International Coaching Federation and European Mentoring and Coaching Council showed considerable overlap. However, the comparison also reiterated the need for competencies specific to health coaches to be made explicit. Discussion: Health coaching has been shown to improve the health outcomes in patients with chronic health conditions. As such, there is a need to build an evidenced-based competency framework specific to health coaches. At present, the lack of a competency framework on which to base health coach training could significantly impact the outcomes of patients receiving health coaching. Practical implications include improving regulation and quality of health coaching, and more importantly, the health outcomes of patients receiving the service. © The Author(s) 2020.

Adolescent popularity : distinct profiles and associations with excessive internet usage and interpersonal sensitivity

- Stavropoulos, Vasileios, Barber, Emily, de Sena Collier, Gabriel, Snodgrass, Jeffrey, Gomez, Rapson

  • Authors: Stavropoulos, Vasileios , Barber, Emily , de Sena Collier, Gabriel , Snodgrass, Jeffrey , Gomez, Rapson
  • Date: 2022
  • Type: Text , Journal article
  • Relation: Child Psychiatry and Human Development Vol. 53, no. 6 (2022), p. 1097-1109
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  • Description: Peer popularity constitutes a pivotal developmental task to adolescents’ current and future adaptation. This study identified distinct adolescent popularity profiles and explored their links with excessive Internet usage and interpersonal sensitivity. The sample included 2090 students attending Greek high schools (Mage = 16.16, SD = 0.91). Their popularity was measured via self-report and peer sociometric means. They also responded to the Internet Addiction Test (IAT) and the Interpersonal Sensitivity subscale of the Symptom Checklist-90-Revised (SCL-90-R). A sequence of latent profile analysis, ANOVAs and linear regression models were performed. Three distinct popularity profiles were revealed: the “Average Confident” (68.4%), the “Socially Vulnerable” (26.8%), and the “Insecure Bi-Strategic” (4.8%). These profiles did not significantly vary regarding their Internet usage and interpersonal sensitivity behaviours. Interestingly, lower self-perceived popularity predicted higher interpersonal sensitivity, whereas higher actual popularity predicted excessive Internet use. Findings have important implications for student-tailored mental health prevention and intervention practices. © 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Self-efficacy, grit and perceptions of rural employment : what changes occur after graduation?

- Terry, Daniel, Peck, Blake, Baker, Ed

  • Authors: Terry, Daniel , Peck, Blake , Baker, Ed
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Online journal of rural nursing and health care Vol. 21, no. 2 (2021), p. 44-68
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  • Description: Purpose: General self-efficacy, occupational self-efficacy, and grit have a correlation with academic and practical success amongst nursing students. The role of these same characteristics during the first 18-24 months following the transition from student to nurse is poorly understood. In addition, when a nursing graduate begins to consider a career in a rural area is also remains unclear. This study sought to understand the change, if any, in general self-efficacy, occupational self-efficacy, grit, and rural employment importance that occurred during this transition period. Sample: Nurses after graduating from a three-year Bachelor of Nursing degree (n=28). Method: A follow-up study of a larger longitudinal mixed-methods cohort design used a survey to examine general self-efficacy, occupational self-efficacy, grit, and rural employment importance among novice nurses. Participants had agreed when completing the initial study as students to participate in a follow-up study 18-24-months after graduating. Findings: Occupational self-efficacy increased as the cohort transitioned from student to professional nurse, while grit was remarkably lower between final year students and novice nurses. No change in earlier measures of general self-efficacy or importance placed on rural careers were detected. Conclusions: Following graduation, new clinicians are focused on building professional identity and the development of foundational skills for practice. Clinical agencies have an opportunity to shift the balance between autonomy and support in order to harness these key characteristics in an effort to improve the longevity and progression of nursing graduates within the nursing profession.