- Title
- SARS-CoV-2 does not replicate in embryonated hen's eggs or in MDCK cell lines
- Creator
- Barr, Ian; Rynehart, Cleve; Whitney, Paul; Druce, Julian
- Date
- 2020
- Type
- Text; Journal article
- Identifier
- http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/173727
- Identifier
- vital:14702
- Identifier
-
https://doi.org/10.2807/1560-7917.ES.2020.25.25.2001122
- Identifier
- ISBN:1560-7917 (ISSN)
- Abstract
- The advent of COVID-19, has posed a risk that human respiratory samples containing human influenza viruses may also contain SARS-CoV-2. This potential risk may lead to SARS-CoV-2 contaminating conventional influenza vaccine production platforms as respiratory samples are used to directly inoculate embryonated hen's eggs and continuous cell lines that are used to isolate and produce influenza vaccines. We investigated the ability of these substrates to propagate SARS-CoV-2 and found that neither could support SARS-CoV-2 replication.
- Publisher
- European Centre for Disease Prevention and Control
- Relation
- Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin Vol. 25, no. 25 (2020), p.
- Rights
- https://creativecommons.org/licenses/by/4.0/
- Rights
- This article is copyright of the authors or their affiliated institutions, 2020. This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence and indicate if changes were made.
- Rights
- Open Access
- Rights
- This metadata is freely available under a CCO license
- Subject
- 0605 Microbiology; 1117 Public Health and Health Services; 1199 Other Medical and Health Sciences; Influenza; SARS-CoV-2,; Vaccine; Respiratory; Air-borne infections; Viral infections; Iinfluenza; Severe acute respiratory syndrome – SARS; Influenza virus,; Biosafety; Vaccines and immunisation; Laboratory
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