Desiccation cracking is a common, undesirable phenomenon in many geotechnical engineering applications, particularly in compacted clay liners as it causes significant changes to the hydraulic and mechanical properties of soils. This is one of the major concerns in design and construction of landfill clay liners in arid regions. This paper reports the findings of laboratory tests conducted to investigate the effects of adding nylon fibre, guar gum and organic enzyme to the soil to control desiccation cracks. Merri-Creek clay, a highly expansive soil from Victoria, Australia, was used in the tests. The additives were mixed with soil in different combinations and in varying proportions. Desiccation tests were conducted in thin, long moulds as in the free shrinkage tests. It was observed that very small quantities of these additives were sufficient to alter the properties of overall mixture. The results indicated that fibre – enzyme is the most effective combination to reduce desiccation cracks. This additive combination contained 0.3% percent of fibres by dry weight of soil and 0.35 g of enzyme per kg of dry soil. There was a modest improvement in dry density in the fibre -enzyme mixture compared to pure Merri-Creek clay. Fibre-enzyme combination also showed the ability to reduce the hydraulic conductivity. It was discovered that guar gum is not desirable to mix with clays in terms of reducing desiccation cracking or decreasing hydraulic conductivity.