A fully automated self-help biopsychosocial transdiagnostic digital intervention to reduce anxiety and/or depression and improve emotional regulation and well-being: pre-follow-up single-arm feasibility trial
- Klein, Britt, Nguyen, Huy, McLaren, Suzanne, Andrews, Brooke, Shandley, Kerrie
- Authors: Klein, Britt , Nguyen, Huy , McLaren, Suzanne , Andrews, Brooke , Shandley, Kerrie
- Date: 2023
- Type: Text , Journal article
- Relation: JMIR Formative Research Vol. 7, no. (2023), p.
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- Description: Background: Anxiety disorders and depression are prevalent disorders with high comorbidity, leading to greater chronicity and severity of symptoms. Given the accessibility to treatment issues, more evaluation is needed to assess the potential benefits of fully automated self-help transdiagnostic digital interventions. Innovating beyond the current transdiagnostic one-size-fits-all shared mechanistic approach may also lead to further improvements. Objective: The primary objective of this study was to explore the preliminary effectiveness and acceptability of a new fully automated self-help biopsychosocial transdiagnostic digital intervention (Life Flex) aimed at treating anxiety and/or depression, as well as improving emotional regulation; emotional, social, and psychological well-being; optimism; and health-related quality of life. Methods: This was a real-world pre-during-post-follow-up feasibility trial design evaluation of Life Flex. Participants were assessed at the preintervention time point (week 0), during intervention (weeks 3 and 5), at the postintervention time point (week 8), and at 1- and 3-month follow-ups (weeks 12 and 20, respectively). Results: The results provided early support for the Life Flex program in reducing anxiety (Generalized Anxiety Disorder 7), depression (Patient Health Questionnaire 9), psychological distress (Kessler 6), and emotional dysregulation (Difficulties in Emotional Regulation 36) and increasing emotional, social, and psychological well-being (Mental Health Continuum-Short Form); optimism (Revised Life Orientation Test); and health-related quality of life (EQ-5D-3L Utility Index and Health Rating; all false discovery rate [FDR] < .001). Large within-group treatment effect sizes (range |d|=0.82 to 1.33) were found for most variables from pre- to postintervention assessments and at the 1- and 3-month follow-up. The exceptions were medium treatment effect sizes for EQ-5D-3L Utility Index (range Cohen d=
- Authors: Klein, Britt , Nguyen, Huy , McLaren, Suzanne , Andrews, Brooke , Shandley, Kerrie
- Date: 2023
- Type: Text , Journal article
- Relation: JMIR Formative Research Vol. 7, no. (2023), p.
- Full Text:
- Reviewed:
- Description: Background: Anxiety disorders and depression are prevalent disorders with high comorbidity, leading to greater chronicity and severity of symptoms. Given the accessibility to treatment issues, more evaluation is needed to assess the potential benefits of fully automated self-help transdiagnostic digital interventions. Innovating beyond the current transdiagnostic one-size-fits-all shared mechanistic approach may also lead to further improvements. Objective: The primary objective of this study was to explore the preliminary effectiveness and acceptability of a new fully automated self-help biopsychosocial transdiagnostic digital intervention (Life Flex) aimed at treating anxiety and/or depression, as well as improving emotional regulation; emotional, social, and psychological well-being; optimism; and health-related quality of life. Methods: This was a real-world pre-during-post-follow-up feasibility trial design evaluation of Life Flex. Participants were assessed at the preintervention time point (week 0), during intervention (weeks 3 and 5), at the postintervention time point (week 8), and at 1- and 3-month follow-ups (weeks 12 and 20, respectively). Results: The results provided early support for the Life Flex program in reducing anxiety (Generalized Anxiety Disorder 7), depression (Patient Health Questionnaire 9), psychological distress (Kessler 6), and emotional dysregulation (Difficulties in Emotional Regulation 36) and increasing emotional, social, and psychological well-being (Mental Health Continuum-Short Form); optimism (Revised Life Orientation Test); and health-related quality of life (EQ-5D-3L Utility Index and Health Rating; all false discovery rate [FDR] < .001). Large within-group treatment effect sizes (range |d|=0.82 to 1.33) were found for most variables from pre- to postintervention assessments and at the 1- and 3-month follow-up. The exceptions were medium treatment effect sizes for EQ-5D-3L Utility Index (range Cohen d=
A low-cost system for monitoring pH, dissolved oxygen and algal density in continuous culture of microalgae
- Nguyen, Dung, Nguyen, Huy, Dang, Huyen, Nguyen, Viet, Nguyen, Linh
- Authors: Nguyen, Dung , Nguyen, Huy , Dang, Huyen , Nguyen, Viet , Nguyen, Linh
- Date: 2022
- Type: Text , Journal article
- Relation: HardwareX Vol. 12, no. (2022), p.
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- Description: In a continuous and closed system of culturing microalgae, constantly monitoring and controlling pH, dissolved oxygen (DO) and microalgal density in the cultivation environment are paramount, which ultimately influence on the growth rate and quality of the microalgae products. Apart from the pH and DO parameters, the density of microalgae can be used to contemplate what light condition in the culture chamber is or when nutrients should be supplemented, which both also decide productivity of the cultivation. Moreover, the microalgal density is considered as an indicator indicating when the microalgae can be harvested. Therefore, this work proposes a low-cost monitoring equipment that can be employed to observe pH, DO and microalgal density over time in a culture environment. The measurements obtained by the proposed monitoring device can be utilized for not only real-time observations but also controlling other sub-systems in a continuous culture model including stirring, ventilating, nutrient supplying and harvesting, which leads to more efficiency in the microalgal production. More importantly, it is proposed to utilize the off-the-shelf materials to fabricate the equipment with a total cost of about 513 EUR, which makes it practical as well as widespread. The proposed monitoring apparatus was validated in a real-world closed system of cultivating a microalgae strain of Chlorella vulgaris. The obtained results indicate that the measurement accuracies are 0.3%, 3.8% and 8.6% for pH, DO and microalgae density quantities, respectively. © 2022 The Author(s)
- Authors: Nguyen, Dung , Nguyen, Huy , Dang, Huyen , Nguyen, Viet , Nguyen, Linh
- Date: 2022
- Type: Text , Journal article
- Relation: HardwareX Vol. 12, no. (2022), p.
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- Description: In a continuous and closed system of culturing microalgae, constantly monitoring and controlling pH, dissolved oxygen (DO) and microalgal density in the cultivation environment are paramount, which ultimately influence on the growth rate and quality of the microalgae products. Apart from the pH and DO parameters, the density of microalgae can be used to contemplate what light condition in the culture chamber is or when nutrients should be supplemented, which both also decide productivity of the cultivation. Moreover, the microalgal density is considered as an indicator indicating when the microalgae can be harvested. Therefore, this work proposes a low-cost monitoring equipment that can be employed to observe pH, DO and microalgal density over time in a culture environment. The measurements obtained by the proposed monitoring device can be utilized for not only real-time observations but also controlling other sub-systems in a continuous culture model including stirring, ventilating, nutrient supplying and harvesting, which leads to more efficiency in the microalgal production. More importantly, it is proposed to utilize the off-the-shelf materials to fabricate the equipment with a total cost of about 513 EUR, which makes it practical as well as widespread. The proposed monitoring apparatus was validated in a real-world closed system of cultivating a microalgae strain of Chlorella vulgaris. The obtained results indicate that the measurement accuracies are 0.3%, 3.8% and 8.6% for pH, DO and microalgae density quantities, respectively. © 2022 The Author(s)
A robust ensemble regression model for reconstructing genetic networks
- Gamage, Hasini, Chetty, Madhu, Lim, Suryani, Hallinan, Jennifer, Nguyen, Huy
- Authors: Gamage, Hasini , Chetty, Madhu , Lim, Suryani , Hallinan, Jennifer , Nguyen, Huy
- Date: 2023
- Type: Text , Conference paper
- Relation: 2023 International Joint Conference on Neural Networks, IJCNN 2023 Vol. 2023-June
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- Description: Genetic networks contain important information about biological processes, including regulatory relationships and gene-gene interactions. Numerous methods, using high-dimensional gene expression data have been developed to capture these interactions. These gene expression data, generated using high-throughput technologies, are prone to noise. However, most existing network inference methods are unable to cope with noisy data, making genetic network reconstruction challenging. In this paper, we propose a novel ensemble regression model combining quantile regression and cross-validated Ridge regression, RidgeCV, to infer interactions from noisy gene expression data. The application of quantile regression to GRN inference is novel, and its design makes it appropriate for noisy data. RidgeCV also addresses other important issues, such as data overfitting and multicollinearity. First, each regression method is independently applied to gene expression data and the output of these methods, in the form of ranked gene lists, is aggregated using a novel gene score-based method by considering the gene rank and model importance. The model importance score is evaluated based on an adjusted coefficient of determination. This method implicitly includes majority voting by averaging each gene score value across all models. The proposed model was tested on the DREAM4 datasets and publicly available small-scale real-world network datasets. Experiments with noisy datasets showed that the proposed ensemble model is more accurate and efficient than other state-of-the-art methods. © 2023 IEEE.
A systematic review of effort-reward imbalance among health workers
- Nguyen, Huy, Le, Ma, Nguyen, Thanh, Ngoc, Dung, Ngoc, Anh, Nguyen, Phuong
- Authors: Nguyen, Huy , Le, Ma , Nguyen, Thanh , Ngoc, Dung , Ngoc, Anh , Nguyen, Phuong
- Date: 2018
- Type: Text , Journal article , Review
- Relation: International Journal of Health Planning and Management Vol. 33, no. 3 (2018), p. e674-e695
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- Description: The purpose of this article is to systematically collate effort-reward imbalance (ERI) rates among health workers internationally and to assess gender differences. The effort-reward (ER) ratio ranges quite widely from 0.47 up to 1.32 and the ERI rate from 3.5% to 80.7%. Many studies suggested that health workers contribute more than they are rewarded, especially in Japan, Vietnam, Greece, and Germany—with ERI rates of 57.1%, 32.3%, 80.7%, and 22.8% to 27.6%, respectively. Institutions can utilize systems such as the new appraisal and reward system, which is based on performance rather than the traditional system, seniority, which creates a more competitive working climate and generates insecurity. Additionally, an increased workload and short stay patients are realities for workers in a health care environment, while the structure of human resources for health care remains inadequate. Gender differences within the ER ratio can be explained by the continued impact of traditional gender roles on attitudes and motivations that place more pressure to succeed for men rather than for women. This systematic review provides some valued evidence for public health strategies to improve the ER balance among health workers in general as well as between genders in particular. An innovative approach for managing human resources for health care is necessary to motivate and value contributions made by health workers. Copyright © 2018 John Wiley & Sons, Ltd.
- Authors: Nguyen, Huy , Le, Ma , Nguyen, Thanh , Ngoc, Dung , Ngoc, Anh , Nguyen, Phuong
- Date: 2018
- Type: Text , Journal article , Review
- Relation: International Journal of Health Planning and Management Vol. 33, no. 3 (2018), p. e674-e695
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- Description: The purpose of this article is to systematically collate effort-reward imbalance (ERI) rates among health workers internationally and to assess gender differences. The effort-reward (ER) ratio ranges quite widely from 0.47 up to 1.32 and the ERI rate from 3.5% to 80.7%. Many studies suggested that health workers contribute more than they are rewarded, especially in Japan, Vietnam, Greece, and Germany—with ERI rates of 57.1%, 32.3%, 80.7%, and 22.8% to 27.6%, respectively. Institutions can utilize systems such as the new appraisal and reward system, which is based on performance rather than the traditional system, seniority, which creates a more competitive working climate and generates insecurity. Additionally, an increased workload and short stay patients are realities for workers in a health care environment, while the structure of human resources for health care remains inadequate. Gender differences within the ER ratio can be explained by the continued impact of traditional gender roles on attitudes and motivations that place more pressure to succeed for men rather than for women. This systematic review provides some valued evidence for public health strategies to improve the ER balance among health workers in general as well as between genders in particular. An innovative approach for managing human resources for health care is necessary to motivate and value contributions made by health workers. Copyright © 2018 John Wiley & Sons, Ltd.
Adherence to antiplatelet therapy after coronary intervention among patients with myocardial infarction attending Vietnam National Heart Institute
- Luu, Ngoc, Dinh, Anh, Nguyen, Thi, Nguyen, Huy
- Authors: Luu, Ngoc , Dinh, Anh , Nguyen, Thi , Nguyen, Huy
- Date: 2019
- Type: Text , Journal article
- Relation: BioMed Research International Vol. 2019, no. (2019), p.
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- Description: Adherence to antiplatelet therapy is critical to successful treatment of cardiovascular conditions. However, little has been known about this issue in the context of constrained resources such as in Vietnam. The objective of this study was to examine the adherence to antiplatelet therapy among patients receiving acute myocardial infarction interventions and its associated factors. In a cross-sectional survey design, 175 adult patients revisiting Vietnam National Heart Institute diagnosed with acute myocardial infarction were approached for data collection from October 2014 to June 2015. Adherence to antiplatelet therapy was assessed by asking patients whether they took taking antiplatelet regularly as per medication (do not miss any dose at the specified time) for any type of antiplatelet (aspirin, clopidogrel, ticlopidine.) during the last month before the participants came back to take re-examinations. The results indicated that the adherence to antiplatelet therapy among patients was quite high at 1 month; it begins to decline by 6 months, 12 months, and more than 12 months (less than 1 month was 90.29%; from 1 to 6 months 88.0%, from 6 to 12 months 75.43%, and after 12 months only 46.29% of patients). Multivariable logistic regression was utilized to detect factors associated with the adherence to antiplatelet therapy. It showed that patients with average income per month of $300 or more (OR=2.92, 95% CI=1.24-6.89), distance to the hospital of less than 50km (OR=2.48, 95% CI: 1.12-5.52), taking medicine under doctor's instructions (OR=3.65; 95% CI=1.13-11.70), and timely re-examination (OR=3.99, 95% CI=1.08-14.73) were more likely to follow the therapy. In general, the study suggested that to increase the likelihood of adherence to antiplatelet therapy it is important to establish a continuous care system after discharging from hospital. © 2019 Ngoc Minh Luu et al.
- Authors: Luu, Ngoc , Dinh, Anh , Nguyen, Thi , Nguyen, Huy
- Date: 2019
- Type: Text , Journal article
- Relation: BioMed Research International Vol. 2019, no. (2019), p.
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- Description: Adherence to antiplatelet therapy is critical to successful treatment of cardiovascular conditions. However, little has been known about this issue in the context of constrained resources such as in Vietnam. The objective of this study was to examine the adherence to antiplatelet therapy among patients receiving acute myocardial infarction interventions and its associated factors. In a cross-sectional survey design, 175 adult patients revisiting Vietnam National Heart Institute diagnosed with acute myocardial infarction were approached for data collection from October 2014 to June 2015. Adherence to antiplatelet therapy was assessed by asking patients whether they took taking antiplatelet regularly as per medication (do not miss any dose at the specified time) for any type of antiplatelet (aspirin, clopidogrel, ticlopidine.) during the last month before the participants came back to take re-examinations. The results indicated that the adherence to antiplatelet therapy among patients was quite high at 1 month; it begins to decline by 6 months, 12 months, and more than 12 months (less than 1 month was 90.29%; from 1 to 6 months 88.0%, from 6 to 12 months 75.43%, and after 12 months only 46.29% of patients). Multivariable logistic regression was utilized to detect factors associated with the adherence to antiplatelet therapy. It showed that patients with average income per month of $300 or more (OR=2.92, 95% CI=1.24-6.89), distance to the hospital of less than 50km (OR=2.48, 95% CI: 1.12-5.52), taking medicine under doctor's instructions (OR=3.65; 95% CI=1.13-11.70), and timely re-examination (OR=3.99, 95% CI=1.08-14.73) were more likely to follow the therapy. In general, the study suggested that to increase the likelihood of adherence to antiplatelet therapy it is important to establish a continuous care system after discharging from hospital. © 2019 Ngoc Minh Luu et al.
Adherence to highly active antiretroviral therapy among people living with HIV and associated high-risk behaviours and clinical characteristics: A cross-sectional survey in Vietnam
- Le, Phuong, Nguyen, Phuong, Nguyen, Huy, Bui, Duc, Vo, Son
- Authors: Le, Phuong , Nguyen, Phuong , Nguyen, Huy , Bui, Duc , Vo, Son
- Date: 2021
- Type: Text , Journal article
- Relation: International Journal of STD and AIDS Vol. 32, no. 10 (2021), p. 911-918
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- Description: Although Vietnam has promoted the utilisation of highly active antiretroviral therapy (HAART) towards HIV elimination targets, adherence to treatment has remained under-investigated. We aimed to describe high-risk behaviours and clinical characteristics by adherence status and to identify the factors associated with non-adherence. We included 426 people living with HIV (PLWH) currently or previously involved in HAART. Most participants were men (75.4%), young (33.6 years), with low income and low education levels. Non-adherent PLWH (11.5%) were more likely to have a larger number of sex partners (p-value = 0.053), sex without condom use (p-value = 0.007) and not receive result at hospital or voluntary test centre (p-value = 0.001). Multiple logistic regression analysis showed that demographic (education levels), sexual risk behaviours (multiple sex partners and sex without using condom) and clinical characteristics (time and facility at first time received HIV-positive result) were associated with HAART non-adherence. There are differences in associated factors between women (education levels and place of HIV testing) and men (multiple sex partners). Gender-specific programs, changing risky behaviours and reducing harms among PLWH may benefit adherence. We highlight the need to improve the quantity and quality of HIV/AIDS services in Vietnam, especially in pre- and post-test counselling, to achieve better HAART adherence, working towards ending AIDS in 2030. © The Author(s) 2021. **Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Huy Nguyen” is provided in this record**
- Authors: Le, Phuong , Nguyen, Phuong , Nguyen, Huy , Bui, Duc , Vo, Son
- Date: 2021
- Type: Text , Journal article
- Relation: International Journal of STD and AIDS Vol. 32, no. 10 (2021), p. 911-918
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- Description: Although Vietnam has promoted the utilisation of highly active antiretroviral therapy (HAART) towards HIV elimination targets, adherence to treatment has remained under-investigated. We aimed to describe high-risk behaviours and clinical characteristics by adherence status and to identify the factors associated with non-adherence. We included 426 people living with HIV (PLWH) currently or previously involved in HAART. Most participants were men (75.4%), young (33.6 years), with low income and low education levels. Non-adherent PLWH (11.5%) were more likely to have a larger number of sex partners (p-value = 0.053), sex without condom use (p-value = 0.007) and not receive result at hospital or voluntary test centre (p-value = 0.001). Multiple logistic regression analysis showed that demographic (education levels), sexual risk behaviours (multiple sex partners and sex without using condom) and clinical characteristics (time and facility at first time received HIV-positive result) were associated with HAART non-adherence. There are differences in associated factors between women (education levels and place of HIV testing) and men (multiple sex partners). Gender-specific programs, changing risky behaviours and reducing harms among PLWH may benefit adherence. We highlight the need to improve the quantity and quality of HIV/AIDS services in Vietnam, especially in pre- and post-test counselling, to achieve better HAART adherence, working towards ending AIDS in 2030. © The Author(s) 2021. **Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Huy Nguyen” is provided in this record**
Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019 : results from the Global Burden of Disease Study 2019
- Kyu, Hmwe, Vongpradith, Avina, Sirota, Sarah, Novotney, Amanda, Troeger, Christopher, Doxey, Matthew, Bender, Rose, Ledesma, Jorge, Biehl, Molly, Albertson, Samuel, Frostad, Joseph, Burkart, Katrin, Bennitt, Fiona, Zhao, Jeff, Gardner, William, Hagins, Hailey, Bryazka, Dana, Dominguez, Regina, Abate, Semagn, Abdelmasseh, Michael, Abdoli, Amir, Abdoli, Gholamreza, Abedi, Aidin, Abedi, Vida, Abegaz, Tadesse, Abidi, Hassan, Aboagye, Richard, Nguyen, Huy, Rahman, Muhammad Aziz
- Authors: Kyu, Hmwe , Vongpradith, Avina , Sirota, Sarah , Novotney, Amanda , Troeger, Christopher , Doxey, Matthew , Bender, Rose , Ledesma, Jorge , Biehl, Molly , Albertson, Samuel , Frostad, Joseph , Burkart, Katrin , Bennitt, Fiona , Zhao, Jeff , Gardner, William , Hagins, Hailey , Bryazka, Dana , Dominguez, Regina , Abate, Semagn , Abdelmasseh, Michael , Abdoli, Amir , Abdoli, Gholamreza , Abedi, Aidin , Abedi, Vida , Abegaz, Tadesse , Abidi, Hassan , Aboagye, Richard , Nguyen, Huy , Rahman, Muhammad Aziz
- Date: 2022
- Type: Text , Journal article
- Relation: The Lancet Infectious Diseases Vol. 22, no. 11 (2022), p. 1626-1647
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- Description: Background: The global burden of lower respiratory infections (LRIs) and corresponding risk factors in children older than 5 years and adults has not been studied as comprehensively as it has been in children younger than 5 years. We assessed the burden and trends of LRIs and risk factors across all age groups by sex, for 204 countries and territories. Methods: In this analysis of data for the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we used clinician-diagnosed pneumonia or bronchiolitis as our case definition for LRIs. We included International Classification of Diseases 9th edition codes 079.6, 466–469, 470.0, 480–482.8, 483.0–483.9, 484.1–484.2, 484.6–484.7, and 487–489 and International Classification of Diseases 10th edition codes A48.1, A70, B97.4–B97.6, J09–J15.8, J16–J16.9, J20–J21.9, J91.0, P23.0–P23.4, and U04–U04.9. We used the Cause of Death Ensemble modelling strategy to analyse 23 109 site-years of vital registration data, 825 site-years of sample vital registration data, 1766 site-years of verbal autopsy data, and 681 site-years of mortality surveillance data. We used DisMod-MR 2.1, a Bayesian meta-regression tool, to analyse age–sex-specific incidence and prevalence data identified via systematic reviews of the literature, population-based survey data, and claims and inpatient data. Additionally, we estimated age–sex-specific LRI mortality that is attributable to the independent effects of 14 risk factors. Findings: Globally, in 2019, we estimated that there were 257 million (95% uncertainty interval [UI] 240–275) LRI incident episodes in males and 232 million (217–248) in females. In the same year, LRIs accounted for 1·30 million (95% UI 1·18–1·42) male deaths and 1·20 million (1·07–1·33) female deaths. Age-standardised incidence and mortality rates were 1·17 times (95% UI 1·16–1·18) and 1·31 times (95% UI 1·23–1·41) greater in males than in females in 2019. Between 1990 and 2019, LRI incidence and mortality rates declined at different rates across age groups and an increase in LRI episodes and deaths was estimated among all adult age groups, with males aged 70 years and older having the highest increase in LRI episodes (126·0% [95% UI 121·4–131·1]) and deaths (100·0% [83·4–115·9]). During the same period, LRI episodes and deaths in children younger than 15 years were estimated to have decreased, and the greatest decline was observed for LRI deaths in males younger than 5 years (–70·7% [–77·2 to –61·8]). The leading risk factors for LRI mortality varied across age groups and sex. More than half of global LRI deaths in children younger than 5 years were attributable to child wasting (population attributable fraction [PAF] 53·0% [95% UI 37·7–61·8] in males and 56·4% [40·7–65·1] in females), and more than a quarter of LRI deaths among those aged 5–14 years were attributable to household air pollution (PAF 26·0% [95% UI 16·6–35·5] for males and PAF 25·8% [16·3–35·4] for females). PAFs of male LRI deaths attributed to smoking were 20·4% (95% UI 15·4–25·2) in those aged 15–49 years, 30·5% (24·1–36·9) in those aged 50–69 years, and 21·9% (16·8–27·3) in those aged 70 years and older. PAFs of female LRI deaths attributed to household air pollution were 21·1% (95% UI 14·5–27·9) in those aged 15–49 years and 18·2% (12·5–24·5) in those aged 50–69 years. For females aged 70 years and older, the leading risk factor, ambient particulate matter, was responsible for 11·7% (95% UI 8·2–15·8) of LRI deaths. Interpretation: The patterns and progress in reducing the burden of LRIs and key risk factors for mortality varied across age groups and sexes. The progress seen in children younger than 5 years was clearly a result of targeted interventions, such as vaccination and reduction of exposure to risk factors. Similar interventions for other age groups could contribute to the achievement of multiple Sustainable Development Goals targets, including promoting well eing at all ages and reducing health inequalities. Interventions, including addressing risk factors such as child wasting, smoking, ambient particulate matter pollution, and household air pollution, would prevent deaths and reduce health disparities. Funding: Bill & Melinda Gates Foundation. © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license **Please note that there are multiple authors for this article therefore only the name of the first 30 including Federation University Australia affiliate “Muhammad Aziz Rahman and Huy Nguyen” is provided in this record**
- Authors: Kyu, Hmwe , Vongpradith, Avina , Sirota, Sarah , Novotney, Amanda , Troeger, Christopher , Doxey, Matthew , Bender, Rose , Ledesma, Jorge , Biehl, Molly , Albertson, Samuel , Frostad, Joseph , Burkart, Katrin , Bennitt, Fiona , Zhao, Jeff , Gardner, William , Hagins, Hailey , Bryazka, Dana , Dominguez, Regina , Abate, Semagn , Abdelmasseh, Michael , Abdoli, Amir , Abdoli, Gholamreza , Abedi, Aidin , Abedi, Vida , Abegaz, Tadesse , Abidi, Hassan , Aboagye, Richard , Nguyen, Huy , Rahman, Muhammad Aziz
- Date: 2022
- Type: Text , Journal article
- Relation: The Lancet Infectious Diseases Vol. 22, no. 11 (2022), p. 1626-1647
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- Description: Background: The global burden of lower respiratory infections (LRIs) and corresponding risk factors in children older than 5 years and adults has not been studied as comprehensively as it has been in children younger than 5 years. We assessed the burden and trends of LRIs and risk factors across all age groups by sex, for 204 countries and territories. Methods: In this analysis of data for the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we used clinician-diagnosed pneumonia or bronchiolitis as our case definition for LRIs. We included International Classification of Diseases 9th edition codes 079.6, 466–469, 470.0, 480–482.8, 483.0–483.9, 484.1–484.2, 484.6–484.7, and 487–489 and International Classification of Diseases 10th edition codes A48.1, A70, B97.4–B97.6, J09–J15.8, J16–J16.9, J20–J21.9, J91.0, P23.0–P23.4, and U04–U04.9. We used the Cause of Death Ensemble modelling strategy to analyse 23 109 site-years of vital registration data, 825 site-years of sample vital registration data, 1766 site-years of verbal autopsy data, and 681 site-years of mortality surveillance data. We used DisMod-MR 2.1, a Bayesian meta-regression tool, to analyse age–sex-specific incidence and prevalence data identified via systematic reviews of the literature, population-based survey data, and claims and inpatient data. Additionally, we estimated age–sex-specific LRI mortality that is attributable to the independent effects of 14 risk factors. Findings: Globally, in 2019, we estimated that there were 257 million (95% uncertainty interval [UI] 240–275) LRI incident episodes in males and 232 million (217–248) in females. In the same year, LRIs accounted for 1·30 million (95% UI 1·18–1·42) male deaths and 1·20 million (1·07–1·33) female deaths. Age-standardised incidence and mortality rates were 1·17 times (95% UI 1·16–1·18) and 1·31 times (95% UI 1·23–1·41) greater in males than in females in 2019. Between 1990 and 2019, LRI incidence and mortality rates declined at different rates across age groups and an increase in LRI episodes and deaths was estimated among all adult age groups, with males aged 70 years and older having the highest increase in LRI episodes (126·0% [95% UI 121·4–131·1]) and deaths (100·0% [83·4–115·9]). During the same period, LRI episodes and deaths in children younger than 15 years were estimated to have decreased, and the greatest decline was observed for LRI deaths in males younger than 5 years (–70·7% [–77·2 to –61·8]). The leading risk factors for LRI mortality varied across age groups and sex. More than half of global LRI deaths in children younger than 5 years were attributable to child wasting (population attributable fraction [PAF] 53·0% [95% UI 37·7–61·8] in males and 56·4% [40·7–65·1] in females), and more than a quarter of LRI deaths among those aged 5–14 years were attributable to household air pollution (PAF 26·0% [95% UI 16·6–35·5] for males and PAF 25·8% [16·3–35·4] for females). PAFs of male LRI deaths attributed to smoking were 20·4% (95% UI 15·4–25·2) in those aged 15–49 years, 30·5% (24·1–36·9) in those aged 50–69 years, and 21·9% (16·8–27·3) in those aged 70 years and older. PAFs of female LRI deaths attributed to household air pollution were 21·1% (95% UI 14·5–27·9) in those aged 15–49 years and 18·2% (12·5–24·5) in those aged 50–69 years. For females aged 70 years and older, the leading risk factor, ambient particulate matter, was responsible for 11·7% (95% UI 8·2–15·8) of LRI deaths. Interpretation: The patterns and progress in reducing the burden of LRIs and key risk factors for mortality varied across age groups and sexes. The progress seen in children younger than 5 years was clearly a result of targeted interventions, such as vaccination and reduction of exposure to risk factors. Similar interventions for other age groups could contribute to the achievement of multiple Sustainable Development Goals targets, including promoting well eing at all ages and reducing health inequalities. Interventions, including addressing risk factors such as child wasting, smoking, ambient particulate matter pollution, and household air pollution, would prevent deaths and reduce health disparities. Funding: Bill & Melinda Gates Foundation. © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license **Please note that there are multiple authors for this article therefore only the name of the first 30 including Federation University Australia affiliate “Muhammad Aziz Rahman and Huy Nguyen” is provided in this record**
An adaptive model of health system organization and responses helped Vietnam to successfully halt the Covid-19 pandemic : what lessons can be learned from a resource-constrained country
- Nguyen, Huy, Van Hoang, Minh, Dao, An, Nguyen, Hoa, Van Nguyen, Tien, Nguyen, Phuong, Khuong, Long, Le, Phuong, Gilmour, Stuart
- Authors: Nguyen, Huy , Van Hoang, Minh , Dao, An , Nguyen, Hoa , Van Nguyen, Tien , Nguyen, Phuong , Khuong, Long , Le, Phuong , Gilmour, Stuart
- Date: 2020
- Type: Text , Journal article
- Relation: International Journal of Health Planning and Management Vol. 35, no. 5 (2020), p. 988-992
- Full Text:
- Reviewed:
- Description: Coping with the COVID-19 pandemic has been painful and no single model for such a purpose is perfect. However, sharing experiences is the best way for countries to learn real-time lessons and adapt to this rapidly changing pandemic. This commentary shares with the international community how an adaptive model of health system organization and responses helped Vietnam to break transmission of coronavirus. We find that an effective model is adaptive to time and context, and mobilizes and engages the wider society. We identify merging of different health system units into Center for Diseases Controls as a health system organization that saved massive resources. The early establishment of a formal committee responding to the pandemic helped unify every public health strategy. The mobilization of different stakeholders and communities added resources and facilitated a synchronous implementation of response strategies, even where those strategies involved significant personal or financial sacrifice. National training on Covid-19 treatment for healthcare professionals across the entire hospital system was useful to expand the health service availability. Quickly published response guidelines helped to activate every level of the health system and involve every sector of society. A strategy of keeping high alert and preemptive action is also essential for coping with the pandemic. © 2020 John Wiley & Sons, Ltd.
- Authors: Nguyen, Huy , Van Hoang, Minh , Dao, An , Nguyen, Hoa , Van Nguyen, Tien , Nguyen, Phuong , Khuong, Long , Le, Phuong , Gilmour, Stuart
- Date: 2020
- Type: Text , Journal article
- Relation: International Journal of Health Planning and Management Vol. 35, no. 5 (2020), p. 988-992
- Full Text:
- Reviewed:
- Description: Coping with the COVID-19 pandemic has been painful and no single model for such a purpose is perfect. However, sharing experiences is the best way for countries to learn real-time lessons and adapt to this rapidly changing pandemic. This commentary shares with the international community how an adaptive model of health system organization and responses helped Vietnam to break transmission of coronavirus. We find that an effective model is adaptive to time and context, and mobilizes and engages the wider society. We identify merging of different health system units into Center for Diseases Controls as a health system organization that saved massive resources. The early establishment of a formal committee responding to the pandemic helped unify every public health strategy. The mobilization of different stakeholders and communities added resources and facilitated a synchronous implementation of response strategies, even where those strategies involved significant personal or financial sacrifice. National training on Covid-19 treatment for healthcare professionals across the entire hospital system was useful to expand the health service availability. Quickly published response guidelines helped to activate every level of the health system and involve every sector of society. A strategy of keeping high alert and preemptive action is also essential for coping with the pandemic. © 2020 John Wiley & Sons, Ltd.
Changes in, and predictors of, quality of life among patients with unstable angina after percutaneous coronary intervention
- Nguyen, Huy, Khuong, Long, Nguyen, Anh, Nguyen, Cham
- Authors: Nguyen, Huy , Khuong, Long , Nguyen, Anh , Nguyen, Cham
- Date: 2021
- Type: Text , Journal article
- Relation: Journal of Evaluation in Clinical Practice Vol. 27, no. 2 (2021), p. 325-332
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- Reviewed:
- Description: Rationale, aims and objectives: Changes in, and predictors of, quality of life (QoL) among unstable angina patients are informative for both clinical and public health practice. However, there is little research on this topic, especially in health care settings with limited resources. This study aims to detect changes in QoL and its associated factors among patients with unstable angina after percutaneous coronary intervention. Methods: A longitudinal design was conducted with two repeated rounds of measurements, 1 and 3 months after intervention, using the generic SF-36 questionnaire, in 120 patients from Vietnam National Heart Institute. A linear mixed-effects model was used to assess changes in patient QoL over time while adjusting for other covariates. Results: Only two out of eight QoL subscales (social functioning and emotional well-being) declined after 1 month, but these tended to rise again after 3 months, while scores of all other QoL subscales increased. Adjusting for covariates, QoL increased slightly after 1 month of intervention (β = 0.65, 95%CI = −0.86 to 2.16) but improved by almost six QoL points after 3 months (β = 5.99, 95%CI = 4.48 to 7.50). Four confounders significantly associated with a decline in QoL were older age, being retired, living in rural areas, and having abnormal troponin level. Conclusion: QoL of the patients with unstable angina improves significantly 3 months after intervention, rather than after 1 month. More attention should be given to patients, who are old, retired, live in rural areas and have abnormal troponin level. © 2020 John Wiley & Sons, Ltd. **Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Huy Nguyen" is provided in this record**
- Authors: Nguyen, Huy , Khuong, Long , Nguyen, Anh , Nguyen, Cham
- Date: 2021
- Type: Text , Journal article
- Relation: Journal of Evaluation in Clinical Practice Vol. 27, no. 2 (2021), p. 325-332
- Full Text:
- Reviewed:
- Description: Rationale, aims and objectives: Changes in, and predictors of, quality of life (QoL) among unstable angina patients are informative for both clinical and public health practice. However, there is little research on this topic, especially in health care settings with limited resources. This study aims to detect changes in QoL and its associated factors among patients with unstable angina after percutaneous coronary intervention. Methods: A longitudinal design was conducted with two repeated rounds of measurements, 1 and 3 months after intervention, using the generic SF-36 questionnaire, in 120 patients from Vietnam National Heart Institute. A linear mixed-effects model was used to assess changes in patient QoL over time while adjusting for other covariates. Results: Only two out of eight QoL subscales (social functioning and emotional well-being) declined after 1 month, but these tended to rise again after 3 months, while scores of all other QoL subscales increased. Adjusting for covariates, QoL increased slightly after 1 month of intervention (β = 0.65, 95%CI = −0.86 to 2.16) but improved by almost six QoL points after 3 months (β = 5.99, 95%CI = 4.48 to 7.50). Four confounders significantly associated with a decline in QoL were older age, being retired, living in rural areas, and having abnormal troponin level. Conclusion: QoL of the patients with unstable angina improves significantly 3 months after intervention, rather than after 1 month. More attention should be given to patients, who are old, retired, live in rural areas and have abnormal troponin level. © 2020 John Wiley & Sons, Ltd. **Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Huy Nguyen" is provided in this record**
Current gaps in the control of cardiovascular disease in Vietnam : a systematic review of Vietnamese-based studies
- Dao, An, Nguyen, Huy, Nguyen, Hoa, Allison, Jeroan, Le, Tung, Bui, Ngoc, Nguyen, Huong, Nguyen, Phuong, Le, Phuong, Van Nguyen, Tien, Chiriboga, German, Goldberg, Robert, Nguyen, Hien
- Authors: Dao, An , Nguyen, Huy , Nguyen, Hoa , Allison, Jeroan , Le, Tung , Bui, Ngoc , Nguyen, Huong , Nguyen, Phuong , Le, Phuong , Van Nguyen, Tien , Chiriboga, German , Goldberg, Robert , Nguyen, Hien
- Date: 2024
- Type: Text , Journal article
- Relation: Journal of Health Management Vol. 26, no. 2 (2024), p. 342-350
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- Description: Cardiovascular disease (CVD) is the leading cause of death among all non-communicable diseases (NCDs) in Vietnam. The objectives of the present study were to analyse contemporary gaps in CVD control studies, which were published in Vietnam between 2013 and 2017. A systematic literature review was performed according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses. Research articles written in English or Vietnamese, published between 2013 and 2017, and focused on the four main WHO themes of CVD control were identified. Among 11,385 Vietnamese-based CVD studies published during this period, only 119 studies (1.0%) were relevant to public health CVD control outcomes, and only 17 of 20 CVD indicators were addressed in these studies. Most studies were published in Vietnamese journals (73.9%), focused on disease and intermediate risk factors (73.9%), were cross-sectional (84.8%) and hospital-based (54.6%). We observed a lack of studies, many of which suffered design and analysis limitations, focused on several WHO themes for effective CVD control. Future Vietnamese-based CVD control studies should focus on the WHO-recommended themes and health indicators in broader community settings to provide better data to inform effective public health policies to control CVD. © 2024 Indian Institute of Health Management Research.
- Authors: Dao, An , Nguyen, Huy , Nguyen, Hoa , Allison, Jeroan , Le, Tung , Bui, Ngoc , Nguyen, Huong , Nguyen, Phuong , Le, Phuong , Van Nguyen, Tien , Chiriboga, German , Goldberg, Robert , Nguyen, Hien
- Date: 2024
- Type: Text , Journal article
- Relation: Journal of Health Management Vol. 26, no. 2 (2024), p. 342-350
- Full Text:
- Reviewed:
- Description: Cardiovascular disease (CVD) is the leading cause of death among all non-communicable diseases (NCDs) in Vietnam. The objectives of the present study were to analyse contemporary gaps in CVD control studies, which were published in Vietnam between 2013 and 2017. A systematic literature review was performed according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses. Research articles written in English or Vietnamese, published between 2013 and 2017, and focused on the four main WHO themes of CVD control were identified. Among 11,385 Vietnamese-based CVD studies published during this period, only 119 studies (1.0%) were relevant to public health CVD control outcomes, and only 17 of 20 CVD indicators were addressed in these studies. Most studies were published in Vietnamese journals (73.9%), focused on disease and intermediate risk factors (73.9%), were cross-sectional (84.8%) and hospital-based (54.6%). We observed a lack of studies, many of which suffered design and analysis limitations, focused on several WHO themes for effective CVD control. Future Vietnamese-based CVD control studies should focus on the WHO-recommended themes and health indicators in broader community settings to provide better data to inform effective public health policies to control CVD. © 2024 Indian Institute of Health Management Research.
Difference in quality of life and associated factors among the elderly in rural Vietnam
- Nguyen, Tien, Nguyen, Huy, Nguyen, Duc, van Nguyen, Thanh, Nguyen, The Phuong
- Authors: Nguyen, Tien , Nguyen, Huy , Nguyen, Duc , van Nguyen, Thanh , Nguyen, The Phuong
- Date: 2017
- Type: Text , Journal article
- Relation: Journal of Preventive Medicine and Hygiene Vol. 58, no. 1 (2017), p. E63-E71
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- Description: Background. In Vietnam today, many generations remain living together in a family. With escalating urbanization and population aging, mental health disorders and the quality of life (QoL) among the elderly are gradually presenting themselves as of great concern. The objective of this study was to examine gender differences in QoL and some associated factors among the elderly in rural Vietnam using the QoL scale of WHO (WHOQOL-BREF). Methods. A cross-sectional study using quantitative methods. Results and Conclusions. The proportion of the elderly men having higher level of QoL in physical health, psychological health and environment was higher than that of their women counterparts. Reversely, of those having medium and lower QoL, females made up a larger proportion than males. The overall QoL score in elderly men (75.32) was higher than that of women (72.32) and the same pattern was witnessed in all four domains of QoL. While higher QoL in elderly men was significantly correlated with 5 factors, aged ≥ 80 years, following Buddhism and Christianity, having better connection and without illness in the past 6 months, these among female counterparts are aged ≥ 80 years, completing secondary level or above, having medium and high socioeconomic status and without illness in the last 6 months. © 2017, Pacini Editore S.p.A. All rights reserved.
- Authors: Nguyen, Tien , Nguyen, Huy , Nguyen, Duc , van Nguyen, Thanh , Nguyen, The Phuong
- Date: 2017
- Type: Text , Journal article
- Relation: Journal of Preventive Medicine and Hygiene Vol. 58, no. 1 (2017), p. E63-E71
- Full Text:
- Reviewed:
- Description: Background. In Vietnam today, many generations remain living together in a family. With escalating urbanization and population aging, mental health disorders and the quality of life (QoL) among the elderly are gradually presenting themselves as of great concern. The objective of this study was to examine gender differences in QoL and some associated factors among the elderly in rural Vietnam using the QoL scale of WHO (WHOQOL-BREF). Methods. A cross-sectional study using quantitative methods. Results and Conclusions. The proportion of the elderly men having higher level of QoL in physical health, psychological health and environment was higher than that of their women counterparts. Reversely, of those having medium and lower QoL, females made up a larger proportion than males. The overall QoL score in elderly men (75.32) was higher than that of women (72.32) and the same pattern was witnessed in all four domains of QoL. While higher QoL in elderly men was significantly correlated with 5 factors, aged ≥ 80 years, following Buddhism and Christianity, having better connection and without illness in the past 6 months, these among female counterparts are aged ≥ 80 years, completing secondary level or above, having medium and high socioeconomic status and without illness in the last 6 months. © 2017, Pacini Editore S.p.A. All rights reserved.
Efficacy of a digital mental health biopsychosocial transdiagnostic intervention with or without therapist assistance for adults with anxiety and depression : adaptive randomized controlled trial
- Andrews, Brooke, Klein, Britt, Nguyen, Huy, Corboy, Denise, McLaren, Suzanne, Watson, Shaun
- Authors: Andrews, Brooke , Klein, Britt , Nguyen, Huy , Corboy, Denise , McLaren, Suzanne , Watson, Shaun
- Date: 2023
- Type: Text , Journal article
- Relation: Journal of Medical Internet Research Vol. 25, no. (2023), p.
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- Reviewed:
- Description: Background: Digital mental health (DMH) interventions incorporating elements that adapt to the evolving needs of consumers have the potential to further our understanding of the optimal intensity of therapist assistance and inform stepped-care models. Objective: The primary objective was to compare the efficacy of a transdiagnostic biopsychosocial DMH program, with or without therapist assistance for adults with subthreshold symptoms or a diagnosis of anxiety or depression. Methods: In a randomized adaptive clinical trial design, all participants had access to the DMH program, with eligibility to have their program augmented with therapist assistance determined by program engagement or symptom severity. Participants who met stepped-care criteria were randomized to have their treatment program augmented with either low-intensity (10 min/week of video chat support for 7 weeks) or high-intensity (50 min/week of video chat support for 7 weeks) therapist assistance. A total of 103 participants (mean age 34.17, SD 10.50 years) were assessed before (week 0), during (weeks 3 and 6), and after the intervention (week 9) and at the 3-month follow-up (week 21). The effects of 3 treatment conditions (DMH program only, DMH program+low-intensity therapist assistance, and DMH program+high-intensity therapist assistance) on changes in the 2 primary outcomes of anxiety (7-item Generalized Anxiety Disorder Scale [GAD-7]) and depression (9-item Patient Health Questionnaire [PHQ-9]) were assessed using the Cohen d, reliable change index, and mixed-effects linear regression analyses. Results: There were no substantial differences in the outcome measures among intervention conditions. However, there were significant time effect changes in most outcomes over time. All 3 intervention conditions demonstrated strong and significant treatment effect changes in GAD-7 and PHQ-9 scores, with absolute Cohen d values ranging from 0.82 to 1.79 (all P<.05). The mixed-effects models revealed that, in the Life Flex program–only condition at week 3, mean GAD-7 and PHQ-9 scores significantly decreased from baseline by 3.54 and 4.38 (all P<.001), respectively. At weeks 6, 9, and 21, GAD-7 and PHQ-9 scores significantly decreased from baseline by at least 6 and 7 points (all P<.001), respectively. Nonresponders at week 3 who were stepped up to therapist assistance increased program engagement and treatment response. At the postintervention time point and 3-month follow-up, 67% (44/65) and 69% (34/49) of the participants, respectively, no longer met diagnostic criteria for anxiety or depression. Conclusions: The findings highlight that early detection of low engagement and non–treatment response presents an opportunity to effectively intervene by incorporating an adaptive design. Although the study findings indicate that therapist assistance was no more effective than the DMH intervention program alone for reducing symptoms of anxiety or depression, the data highlight the potential influence of participant selection bias and participant preferences within stepped-care treatment models. ©Brooke Andrews, Britt Klein, Huy Van Nguyen, Denise Corboy, Suzanne McLaren, Shaun Watson.
- Authors: Andrews, Brooke , Klein, Britt , Nguyen, Huy , Corboy, Denise , McLaren, Suzanne , Watson, Shaun
- Date: 2023
- Type: Text , Journal article
- Relation: Journal of Medical Internet Research Vol. 25, no. (2023), p.
- Full Text:
- Reviewed:
- Description: Background: Digital mental health (DMH) interventions incorporating elements that adapt to the evolving needs of consumers have the potential to further our understanding of the optimal intensity of therapist assistance and inform stepped-care models. Objective: The primary objective was to compare the efficacy of a transdiagnostic biopsychosocial DMH program, with or without therapist assistance for adults with subthreshold symptoms or a diagnosis of anxiety or depression. Methods: In a randomized adaptive clinical trial design, all participants had access to the DMH program, with eligibility to have their program augmented with therapist assistance determined by program engagement or symptom severity. Participants who met stepped-care criteria were randomized to have their treatment program augmented with either low-intensity (10 min/week of video chat support for 7 weeks) or high-intensity (50 min/week of video chat support for 7 weeks) therapist assistance. A total of 103 participants (mean age 34.17, SD 10.50 years) were assessed before (week 0), during (weeks 3 and 6), and after the intervention (week 9) and at the 3-month follow-up (week 21). The effects of 3 treatment conditions (DMH program only, DMH program+low-intensity therapist assistance, and DMH program+high-intensity therapist assistance) on changes in the 2 primary outcomes of anxiety (7-item Generalized Anxiety Disorder Scale [GAD-7]) and depression (9-item Patient Health Questionnaire [PHQ-9]) were assessed using the Cohen d, reliable change index, and mixed-effects linear regression analyses. Results: There were no substantial differences in the outcome measures among intervention conditions. However, there were significant time effect changes in most outcomes over time. All 3 intervention conditions demonstrated strong and significant treatment effect changes in GAD-7 and PHQ-9 scores, with absolute Cohen d values ranging from 0.82 to 1.79 (all P<.05). The mixed-effects models revealed that, in the Life Flex program–only condition at week 3, mean GAD-7 and PHQ-9 scores significantly decreased from baseline by 3.54 and 4.38 (all P<.001), respectively. At weeks 6, 9, and 21, GAD-7 and PHQ-9 scores significantly decreased from baseline by at least 6 and 7 points (all P<.001), respectively. Nonresponders at week 3 who were stepped up to therapist assistance increased program engagement and treatment response. At the postintervention time point and 3-month follow-up, 67% (44/65) and 69% (34/49) of the participants, respectively, no longer met diagnostic criteria for anxiety or depression. Conclusions: The findings highlight that early detection of low engagement and non–treatment response presents an opportunity to effectively intervene by incorporating an adaptive design. Although the study findings indicate that therapist assistance was no more effective than the DMH intervention program alone for reducing symptoms of anxiety or depression, the data highlight the potential influence of participant selection bias and participant preferences within stepped-care treatment models. ©Brooke Andrews, Britt Klein, Huy Van Nguyen, Denise Corboy, Suzanne McLaren, Shaun Watson.
- Klein, Britt, Oldenhof, Erin, Nguyen, Huy, Schattner, Peter, Shandley, Kerrie
- Authors: Klein, Britt , Oldenhof, Erin , Nguyen, Huy , Schattner, Peter , Shandley, Kerrie
- Date: 2023
- Type: Text , Journal article
- Relation: Journal of Behavioral and Cognitive Therapy Vol. 33, no. 3 (2023), p. 179-193
- Full Text: false
- Reviewed:
- Description: Introduction: Benzodiazepines (BDZs) are often inappropriately prescribed to manage anxiety and insomnia for longer-term use, despite guidelines recommending short-term use (i.e., <4 weeks). A range of harms can occur rapidly with regular use, and dependence can make stopping BDZs challenging. Evidence shows that a combination of BDZ tapering and psychological support are effective interventions, yet are not widely accessible. Methods: This was a one-group pilot trial of a 6-week fully automated self-help BDZ digital intervention (‘BDZ digital health’), providing guidance on how to safely taper BDZs as well as psychological support. The trial was undertaken with Australian adults considering a reduction and/or withdrawal from their BDZ (N = 43). Participants were assessed at pre-intervention (Week 0), during intervention (Week 3), post-intervention (Week 6), and at a 3- and 6-month follow-up (Week 18 and 30 respectively). Results: Reductions in BDZ use and self-reported dependency were observed over the course of the intervention. Significant symptom reductions in anxiety, insomnia, depression, psychological distress, and emotional dysregulation, as well as improvements in mental wellbeing and quality of life were observed when looking across all timepoints. However, the specific assessment timepoint changes for depression and psychological distress did not reach significance from the pre- to post-intervention timepoint. The intervention acceptability ratings were in the moderately high to high range. Discussion: The preliminary results of the pilot trial suggest that BDZ digital health is an acceptable and promising self-help digital intervention to assist adults reducing and withdrawing from their BDZs, and to improve their mental health and wellbeing. Trial registration: ACTRN12617000574347 (24/04/2017). © 2023 Association Française de Therapie Comportementale et Cognitive
Factors associated with depression among the elderly living in urban Vietnam
- Dao, An, Nguyen, Van, Nguyen, Huy, Nguyen, Lien
- Authors: Dao, An , Nguyen, Van , Nguyen, Huy , Nguyen, Lien
- Date: 2018
- Type: Text , Journal article
- Relation: BioMed Research International Vol. 2018, no. (2018), p.
- Full Text:
- Reviewed:
- Description: The proportion of elderly people in big cities of developing countries, including Vietnam, is rapidly increasing during the age of rampant urbanization. This is being followed by a sustained rise of illnesses, especially mental health issues. The objective of this study was to analyze the association between depression and the factors associated with depression among the elderly. In a cross-sectional study, 299 elderly living in Hanoi, Vietnam, were approached for data collection. Self-reported depression among the elderly was 66.9% (32.8% mild, 30.4% moderate, and 3.7% severe cases). In multivariate analysis, there were significant associations between age, number of physical activities, number of medicine intake, and 3 domains of quality of life (physical health, psychological health, and environmental health) and depression. Age and the number of medicine intake are positively correlated with depression, accounting for 57.94% and 58.93%, respectively. On the contrary, the number of physical activities and the 3 domains of quality life mentioned above are negatively correlated with depression. In the urban setting of a developing country like Vietnam, the elderly have experienced common depression. Recognizing depression among the elderly - which is individual and social - helps us design public health programs. Screening for early depression, joining social programming, and participating in physical activities may improve the mental life of the elderly. © 2018 An T. M. Dao et al.
- Authors: Dao, An , Nguyen, Van , Nguyen, Huy , Nguyen, Lien
- Date: 2018
- Type: Text , Journal article
- Relation: BioMed Research International Vol. 2018, no. (2018), p.
- Full Text:
- Reviewed:
- Description: The proportion of elderly people in big cities of developing countries, including Vietnam, is rapidly increasing during the age of rampant urbanization. This is being followed by a sustained rise of illnesses, especially mental health issues. The objective of this study was to analyze the association between depression and the factors associated with depression among the elderly. In a cross-sectional study, 299 elderly living in Hanoi, Vietnam, were approached for data collection. Self-reported depression among the elderly was 66.9% (32.8% mild, 30.4% moderate, and 3.7% severe cases). In multivariate analysis, there were significant associations between age, number of physical activities, number of medicine intake, and 3 domains of quality of life (physical health, psychological health, and environmental health) and depression. Age and the number of medicine intake are positively correlated with depression, accounting for 57.94% and 58.93%, respectively. On the contrary, the number of physical activities and the 3 domains of quality life mentioned above are negatively correlated with depression. In the urban setting of a developing country like Vietnam, the elderly have experienced common depression. Recognizing depression among the elderly - which is individual and social - helps us design public health programs. Screening for early depression, joining social programming, and participating in physical activities may improve the mental life of the elderly. © 2018 An T. M. Dao et al.
Factors associated with high-risk behaviors of people newly diagnosed with HIV/AIDS : results from a cross-sectional study in Vietnam
- Nguyen, Phuong, Gilmour, Stuart, Le, Phuong, Nguyen, Trung, Tanuma, Junko, Nguyen, Huy
- Authors: Nguyen, Phuong , Gilmour, Stuart , Le, Phuong , Nguyen, Trung , Tanuma, Junko , Nguyen, Huy
- Date: 2021
- Type: Text , Journal article
- Relation: AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV Vol. 33, no. 5 (2021), p. 607-615
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- Reviewed:
- Description: Towards the elimination of this global epidemic, understanding the high-risk behaviors of people newly diagnosed with HIV/AIDS (PNDWH) is essential. This study aimed to describe the general characteristics and high-risk behaviors of PNDWH and identify associated factors for adopting high-risk behaviors. A cross-sectional survey was conducted in Vietnam to explore the high-risk behaviors of 506 PNDWH. Associated factors were identified using multivariable logistic regressions. 83.2% of participants had sex without using a condom, and 27.9% had more than two sex partners. Among injected drug users, 44% had shared needles with an average number of 2.1 shared partners. Male, Kinh ethnicity (Vietnamese), high income, and high educational level were risk factors for high-risk behaviors. Our findings revealed the first time a comprehensive picture of PNDWH and emphasized the high prevalence of STIs, including untreated STIs and the long delay since the early HIV diagnosis. Also, our model found much higher risk behaviors among participants who were non-adherent to ART and those currently enrolled in ART. By better managing newly-diagnosed cases, better integrating STI management services and prevention consultants, as well as improving ART adherence programs, Vietnam can make better progress towards the complete control of HIV for its most vulnerable populations. © 2020 Informa UK Limited, trading as Taylor & Francis Group.
- Authors: Nguyen, Phuong , Gilmour, Stuart , Le, Phuong , Nguyen, Trung , Tanuma, Junko , Nguyen, Huy
- Date: 2021
- Type: Text , Journal article
- Relation: AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV Vol. 33, no. 5 (2021), p. 607-615
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- Description: Towards the elimination of this global epidemic, understanding the high-risk behaviors of people newly diagnosed with HIV/AIDS (PNDWH) is essential. This study aimed to describe the general characteristics and high-risk behaviors of PNDWH and identify associated factors for adopting high-risk behaviors. A cross-sectional survey was conducted in Vietnam to explore the high-risk behaviors of 506 PNDWH. Associated factors were identified using multivariable logistic regressions. 83.2% of participants had sex without using a condom, and 27.9% had more than two sex partners. Among injected drug users, 44% had shared needles with an average number of 2.1 shared partners. Male, Kinh ethnicity (Vietnamese), high income, and high educational level were risk factors for high-risk behaviors. Our findings revealed the first time a comprehensive picture of PNDWH and emphasized the high prevalence of STIs, including untreated STIs and the long delay since the early HIV diagnosis. Also, our model found much higher risk behaviors among participants who were non-adherent to ART and those currently enrolled in ART. By better managing newly-diagnosed cases, better integrating STI management services and prevention consultants, as well as improving ART adherence programs, Vietnam can make better progress towards the complete control of HIV for its most vulnerable populations. © 2020 Informa UK Limited, trading as Taylor & Francis Group.
Factors associated with job satisfaction among district hospital health workers in Northern Vietnam : a cross-sectional study
- Nguyen, Huy, Duong, Huong, Vu, Toan
- Authors: Nguyen, Huy , Duong, Huong , Vu, Toan
- Date: 2017
- Type: Text , Journal article
- Relation: International Journal of Health Planning and Management Vol. 32, no. 2 (2017), p. 163-179
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- Description: Background: In many developing countries, including Vietnam, little is known about job satisfaction among lower level-health staff. The purpose of this study was to assess job satisfaction and its determinants among district hospital health staff. Methods: In a cross-sectional quantitative study, 128 health staff from a rural district hospital in Northern Vietnam were approached for data collection. Regression techniques were adopted to assess factors associated with several types of job satisfaction. Results: Overall job satisfaction was moderately high, ranging from 69% to 91%. Across all dimensions, health workers showed their highest satisfaction with co-worker relationships, while, in comparison, it was much lower for their supervisor's style and relationship. However, they claimed their lowest satisfaction with compensation and benefits. In final multivariate models, females and those satisfied with knowledge, skills and job performance were most likely to be satisfied with relationships with co-workers. Staff who were married, received a low pay, who were not satisfied with supervisor style and relationships and who were not satisfied with staff training, development opportunities were least likely to be satisfied with compensation and benefits. Conclusions: The study findings highlight an important need for designing an intervention program that considers organizational factors. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.
- Authors: Nguyen, Huy , Duong, Huong , Vu, Toan
- Date: 2017
- Type: Text , Journal article
- Relation: International Journal of Health Planning and Management Vol. 32, no. 2 (2017), p. 163-179
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- Description: Background: In many developing countries, including Vietnam, little is known about job satisfaction among lower level-health staff. The purpose of this study was to assess job satisfaction and its determinants among district hospital health staff. Methods: In a cross-sectional quantitative study, 128 health staff from a rural district hospital in Northern Vietnam were approached for data collection. Regression techniques were adopted to assess factors associated with several types of job satisfaction. Results: Overall job satisfaction was moderately high, ranging from 69% to 91%. Across all dimensions, health workers showed their highest satisfaction with co-worker relationships, while, in comparison, it was much lower for their supervisor's style and relationship. However, they claimed their lowest satisfaction with compensation and benefits. In final multivariate models, females and those satisfied with knowledge, skills and job performance were most likely to be satisfied with relationships with co-workers. Staff who were married, received a low pay, who were not satisfied with supervisor style and relationships and who were not satisfied with staff training, development opportunities were least likely to be satisfied with compensation and benefits. Conclusions: The study findings highlight an important need for designing an intervention program that considers organizational factors. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.
Factors associated with risky alcohol consumption among male street laborers in urban Vietnam
- Mylona, Lamprini, Nguyen, Huy, Ha, Pham, Riggi, Emilia, Marrone, Gaetano
- Authors: Mylona, Lamprini , Nguyen, Huy , Ha, Pham , Riggi, Emilia , Marrone, Gaetano
- Date: 2017
- Type: Text , Journal article
- Relation: Substance Use and Misuse Vol. 52, no. 9 (2017), p. 1170-1180
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- Description: Background: Alcohol consumption is of global concern. However, drinking patterns and associated factors remain under-investigated, especially among low socioeconomic groups such as street laborers. Objective: Using the social cognitive model as a framework for the study we aimed to identify factors associated with risky alcohol consumption. Methods: In a cross-sectional study using structured questionnaires, 450 male street laborers searching for casual works in Hanoi, Vietnam were interviewed. A logistic regression was applied in order to detect predictors of risky alcohol drinking. Results: During the last month, 45% of the participants reported daily consumption while the other 55% consumed weekly or less. Among the drinkers (416 out of 450, 92%), 27% were identified as high-risk drinkers who reported more than 14 standard drinks per week, while only 8% were lifetime abstainers. The multivariable logistic regression showed that older age, higher income were positively associated with a higher likelihood of drinking alcohol, while high school level negatively. The environmental predictor was the higher level of peer connection. The association between drinking and risky behavior was found positive with regards to the number of sexual partners. Conclusions: The study suggests that male street laborers are vulnerable to health risks. Decision makers should note that a significant proportion of this target group exceeds the guidelines for alcohol use and this should be included in future interventions or further research. A multisectoral approach together with an important strategy of education is needed to control alcohol use. © 2017 Taylor & Francis Group, LLC.
- Authors: Mylona, Lamprini , Nguyen, Huy , Ha, Pham , Riggi, Emilia , Marrone, Gaetano
- Date: 2017
- Type: Text , Journal article
- Relation: Substance Use and Misuse Vol. 52, no. 9 (2017), p. 1170-1180
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- Description: Background: Alcohol consumption is of global concern. However, drinking patterns and associated factors remain under-investigated, especially among low socioeconomic groups such as street laborers. Objective: Using the social cognitive model as a framework for the study we aimed to identify factors associated with risky alcohol consumption. Methods: In a cross-sectional study using structured questionnaires, 450 male street laborers searching for casual works in Hanoi, Vietnam were interviewed. A logistic regression was applied in order to detect predictors of risky alcohol drinking. Results: During the last month, 45% of the participants reported daily consumption while the other 55% consumed weekly or less. Among the drinkers (416 out of 450, 92%), 27% were identified as high-risk drinkers who reported more than 14 standard drinks per week, while only 8% were lifetime abstainers. The multivariable logistic regression showed that older age, higher income were positively associated with a higher likelihood of drinking alcohol, while high school level negatively. The environmental predictor was the higher level of peer connection. The association between drinking and risky behavior was found positive with regards to the number of sexual partners. Conclusions: The study suggests that male street laborers are vulnerable to health risks. Decision makers should note that a significant proportion of this target group exceeds the guidelines for alcohol use and this should be included in future interventions or further research. A multisectoral approach together with an important strategy of education is needed to control alcohol use. © 2017 Taylor & Francis Group, LLC.
Gambling-related suicide in Victoria, Australia : a population-based cross-sectional study
- Rintoul, Angela, Dwyer, Jeremy, Millar, Ciara, Bugeja, Lyndal, Nguyen, Huy
- Authors: Rintoul, Angela , Dwyer, Jeremy , Millar, Ciara , Bugeja, Lyndal , Nguyen, Huy
- Date: 2023
- Type: Text , Journal article
- Relation: The Lancet Regional Health - Western Pacific Vol. 41, no. (2023), p.
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- Description: Background: Gambling is associated with serious harms to health, including suicide. Yet public health systems for recording the role of gambling in suicide deaths are relatively underdeveloped. This study contributes to the understanding of this relationship. Methods: A population-based cross-sectional study of suicides reported to the Coroners Court of Victoria between 2009 and 2016 was performed to identify the incidence and characteristics of gambling-related suicides (GRS). Findings: From 2009 to 2016 there were 4788 suicide deaths in Victoria. Of these, 184 were identified as direct GRS and a further 17 were GRS by ‘affected others’. Together, these GRS comprise 4.2% of all suicides in Victoria over this eight-year period. Direct GRS account for an annual average rate of 5.13 GRS per million Victorian adults. GRS were significantly more likely to be male (n = 153, 83%), than the Victorian population of total suicide deaths and significantly more likely to occur among those most disadvantaged. Family members and friends were more likely than clinicians to know about the deceased gambling. Interpretation: Given that gambling is not routinely investigated by coroners and may be hidden from family, friends, and health professionals, this is an underestimate of the true scale of the GRS in Victoria. A range of measures should be introduced to prevent, screen, support, and treat gambling harm. Family members and friends should also be provided with help services. Preventing gambling-related harm through public health measures could significantly reduce suicidality and suicide, both in Australia and globally. Funding: Federation University Australia, Coroners Court of Victoria, Suicide Prevention Australia. © 2023 The Authors
- Authors: Rintoul, Angela , Dwyer, Jeremy , Millar, Ciara , Bugeja, Lyndal , Nguyen, Huy
- Date: 2023
- Type: Text , Journal article
- Relation: The Lancet Regional Health - Western Pacific Vol. 41, no. (2023), p.
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- Description: Background: Gambling is associated with serious harms to health, including suicide. Yet public health systems for recording the role of gambling in suicide deaths are relatively underdeveloped. This study contributes to the understanding of this relationship. Methods: A population-based cross-sectional study of suicides reported to the Coroners Court of Victoria between 2009 and 2016 was performed to identify the incidence and characteristics of gambling-related suicides (GRS). Findings: From 2009 to 2016 there were 4788 suicide deaths in Victoria. Of these, 184 were identified as direct GRS and a further 17 were GRS by ‘affected others’. Together, these GRS comprise 4.2% of all suicides in Victoria over this eight-year period. Direct GRS account for an annual average rate of 5.13 GRS per million Victorian adults. GRS were significantly more likely to be male (n = 153, 83%), than the Victorian population of total suicide deaths and significantly more likely to occur among those most disadvantaged. Family members and friends were more likely than clinicians to know about the deceased gambling. Interpretation: Given that gambling is not routinely investigated by coroners and may be hidden from family, friends, and health professionals, this is an underestimate of the true scale of the GRS in Victoria. A range of measures should be introduced to prevent, screen, support, and treat gambling harm. Family members and friends should also be provided with help services. Preventing gambling-related harm through public health measures could significantly reduce suicidality and suicide, both in Australia and globally. Funding: Federation University Australia, Coroners Court of Victoria, Suicide Prevention Australia. © 2023 The Authors
- Ha, Diep, Nguyen, Huy, Dao, An, Golley, Rebecca, Thomson, W., Manton, David, Leary, Sam, Scott, Jane, Spencer, Andrew, Do, Loc
- Authors: Ha, Diep , Nguyen, Huy , Dao, An , Golley, Rebecca , Thomson, W. , Manton, David , Leary, Sam , Scott, Jane , Spencer, Andrew , Do, Loc
- Date: 2022
- Type: Text , Journal article
- Relation: Journal of Dentistry Vol. 122, no. (2022), p.
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- Description: Objectives: To investigate the trajectory of maternal intake of sugar-sweetened beverages (SSB) during the first five years of their child's life and its effect on the child's dental caries at five years-of-age. Methods: This is an ongoing prospective population-based birth cohort study in Adelaide, Australia. Mothers completed questionnaires on their SSB intake, socioeconomic factors and health behaviors at the birth of their child and at the ages of one, two and five years. Child dental caries measured as decayed, missing, or filled tooth surfaces was collected by oral examination. Maternal SSB intake was used to estimate the trajectory of SSB intake. The trajectories then became the main exposure of the study. Dental caries at age five years were the primary outcomes. Adjusted mean- and prevalence-ratios were estimated for dental caries, controlling for confounders. Results: 879 children had dental examinations at five years-of-age. Group-based trajectory modeling identified three trajectories of maternal SSB intake: ‘Stable low’ (40.8%), ‘Moderate but increasing’ (13.6%), and ‘High early’ trajectory (45.6%). Multivariable regression analysis found children of mothers in the ‘High early’ and ‘Moderate but increasing’ groups to have greater experience of dental caries (MR: 1.37 (95%CI 1.01–1.67), and 1.24 (95%CI 0.96–1.60) than those in the ‘Stable low’ trajectory, respectively. Conclusion: Maternal consumption of SSB during pregnancy and in the early postnatal period influenced their offspring's oral health. It is important to create a low-sugar environment from early childhood. The results suggest that health promotion activities need to be delivered to expecting women or soon after childbirth. © 2022
Health service utilization among people with noncommunicable diseases in rural Vietnam
- Van Minh, Hoang, Oh, Juhwan, Giang, Kim, Nguyen, Bao, Nguyen, Huy
- Authors: Van Minh, Hoang , Oh, Juhwan , Giang, Kim , Nguyen, Bao , Nguyen, Huy
- Date: 2018
- Type: Text , Journal article
- Relation: Journal of public health management and practice : JPHMP Vol. 24, no. (2018), p. S60-S66
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- Description: CONTEXT: Chronic noncommunicable diseases (NCDs) have been shown to be major causes of morbidity and mortality in hospitals for the whole country. OBJECTIVE: This study aims to describe the situation of health service utilization among people with NCDs in a rural area and identify association between the situation of health service utilization among people with chronic diseases and their socioeconomic status. DESIGN: This was a cross-sectional study. SETTING: A rural district located in the North of Vietnam. PARTICIPANTS: People 15 years of age and older. Health service utilization was analyzed only among people who reported having NCD. MAIN OUTCOME MEASURES: Data were collected through a personal household interview conducted by 12 trained field workers. The dependent variable is health care service utilization among people with chronic NCDs. The explanatory variables include both household attributes such as household economic conditions, and so forth, and individual characteristics. RESULTS: Eighteen percent of the adults and 51% of the elderly respondents reported having at least 1 of the NCDs. The proportions of people with NCDs who used at least 1 outpatient service and used at least 1 inpatient health service during the last 12 months were 68.1% and 10.7%, respectively (the nonutilization rates of 31.9% and 89.3%, respectively). The statistically significant correlates of health care service utilization among people with NCDs were ethnicity (ethnic minority was significantly associated with a lower odds of health care service utilization) and health insurance (no health insurance was significantly associated with lower odds of health care service utilization). CONCLUSION: Given the evidence from this study, actions to improve access to health care services among people with NCDs are clearly needed. The capacity of primary health care system for the prevention and control of NCDs should be ranked a top priority. **Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Huy Nguyen” is provided in this record**