- Title
- Does type 1 diabetes mellitus affect Achilles tendon response to a 10 km run? A case control study
- Creator
- Wong, Andrea; Docking, Sean; Cook, Jill; Gaida, Jamie
- Date
- 2015
- Type
- Text; Journal article
- Identifier
- http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/100722
- Identifier
- vital:10521
- Identifier
-
https://doi.org/10.1186/s12891-015-0803-z
- Identifier
- ISSN:1471-2474
- Abstract
- Background: Achilles tendon structure deteriorates 2-days after maximal loading in elite athletes. The load-response behaviour of tendons may be altered in type 1 diabetes mellitus (T1DM) as hyperglycaemia accelerates collagen cross-linking. This study compared Achilles tendon load-response in participants with T1DM and controls. Methods: Achilles tendon structure was quantified at day-0, day-2 and day-4 after a 10 km run. Ultrasound tissue characterisation (UTC) measures tendon structural integrity by classifying pixels as echo-type I, II, III or IV. Echo-type I has the most aligned collagen fibrils and IV has the least. Results: Participants were 7 individuals with T1DM and 10 controls. All regularly ran distances greater than 5 km and VISA-A scores indicated good tendon function (T1DM = 94 +/- 11, control = 94 +/- 10). There were no diabetic complications and HbA1c was 8.7 +/- 2.6 mmol/mol for T1DM and 5.3 +/- 0.4 mmol/mol for control groups. Baseline tendon structure was similar in T1DM and control groups -UTC echo-types (I-IV) and anterior-posterior thickness were all p > 0.05. No response to load was seen in either T1DM or control group over the 4-days post exercise. Conclusion: Active individuals with T1DM do not have a heightened Achilles tendon response to load, which suggests no increased risk of tendon injury. We cannot extrapolate these findings to sedentary individuals with T1DM.
- Publisher
- BioMed Central
- Relation
- Bmc Musculoskeletal Disorders Vol. 16, no. (2015), p. 1-7
- Rights
- Copyright © 2015 Wong et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver applies to the data made available in this article, unless otherwise stated.
- Rights
- Open Access
- Rights
- http://creativecommons.org/publicdomain/zero/1.0/
- Rights
- This metadata is freely available under a CCO license
- Subject
- 1103 Clinical Sciences; Exercise; Imaging; T1DM; Achilles; Tendon
- Full Text
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