- Title
- Wild Australian shorebirds as reservoirs of pathogenic bacteria and antimicrobial resistance
- Creator
- Smith, Hannah
- Date
- 2020
- Type
- Text; Thesis; PhD
- Identifier
- http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/179783
- Identifier
- vital:15674
- Abstract
- Many existing and emerging diseases of humans are of zoonotic origin. In addition, the development of antimicrobial resistance (AMR) presents a serious risk for hospitals, agriculture, and the community. Habitat loss and degradation are forcing many wild animal populations into closer contact with human populations, presenting opportunities for the introduction and transmission of bacterial diseases. In Australia, many shorebird species undertake yearly migrations to and from breeding grounds in the high Artic, and during their migrations they pass over one-third of the human population. To determine if shorebirds are reservoirs of pathogenic bacteria the research presented in this thesis investigated the presence of three common enteric bacterial pathogens in twelve species of wild Australian shorebird; followed by AMR profiles of isolates, and genetic characterisation of selected isolates. In total, 1022 individual birds were sampled across three Australian states and tested for the presence of three potentially zoonotic pathogens; Escherichia coli, Enterococcus spp., and Salmonella spp. Two-hundred and six E. coli, 266 Enterococcus, and 20 Salmonella isolates were recovered, with AMR observed in 42% of E. coli isolates, 85% of Enterococcus isolates, and 10% of Salmonella isolates. Sedentary birds were more likely to carry AMR bacteria than migratory birds. A selection of E. coli isolates (n=16) underwent whole genome sequencing, and analysis of their genomes indicated a high level of genetic diversity with each isolate having a unique serotype. A total of 33 recognised virulence genes and eight AMR genes were detected. An important food-borne pathogen, Salmonella enterica serovar Hvittingfoss, was also recovered from one species of bird. This study shows that wild shorebirds can carry pathogenic enteric bacteria. While migratory birds may be less likely to harbour AMR bacteria relative to sedentary birds, they pose the potential to act as vectors for enteric and foodborne pathogens.; Doctor of Philosophy
- Publisher
- Federation University Australia
- Rights
- All metadata describing materials held in, or linked to, the repository is freely available under a CC0 licence
- Rights
- Copyright Hannah Smith
- Rights
- Open Access
- Subject
- Antimicrobial resistance,; Shorebirds; Pathogenic bacteria
- Full Text
- Thesis Supervisor
- Greenhill, Andrew
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