The pressure of finding human hypertension genes : New tools, old dilemmas

Title: The pressure of finding human hypertension genes : New tools, old dilemmas
Creator: Charchar, Fadi; Zimmerli, Lukas; Tomaszewski, Maciej
Date: 2008
Type: Text; Journal article
Identifier: http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/43810
Identifier: vital:1772
Identifier: https://doi.org/10.1038/jhh.2008.67
Identifier: ISSN:0950-9240
Abstract: Researchers in hypertension genetics feel like they are left behind again. It always seems that the 'other' complex diseases are ahead in the race. Evolving new technologies in the form of genome-wide arrays and 'omics' technologies mean that investigators can now potentially identify many novel disease factors in one large-scale experiment. Hypertension research now faces the challenge of where to go next after the first genome-wide association experiments failed to provide robust candidates. In this review, we contemplate the old dilemma of whether such genes may ever be found; however, we believe advancing technologies and plummeting costs of large-scale experiments will contribute to the identification of novel molecules that underlie essential hypertension.
Publisher: Nature Publishing Group
Relation: Journal of Human Hypertension Vol. 22, no. (2008), p. 821–828
Rights: Copyright Nature Publishing Group
Rights: This metadata is freely available under a CCO license
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