Exploring novel features and decision rules to identify cardiovascular autonomic neuropathy using a hybrid of wrapper-filter based feature selection
- Authors: Huda, Shamsul , Jelinek, Herbert , Ray, Biplob , Stranieri, Andrew , Yearwood, John
- Date: 2010
- Type: Text , Conference paper
- Relation: Paper presented at the 2010 6th International Conference on Intelligent Sensors, Sensor Networks and Information Processing, ISSNIP 2010 p. 297-302
- Full Text:
- Reviewed:
- Description: Cardiovascular autonomic neuropathy (CAN) is one of the important causes of mortality among diabetes patients. Statistics shows that more than 22% of people with type 2 diabetes mellitus suffer from CAN and which in turn leads to cardiovascular disease (heart attack, stroke). Therefore early detection of CAN could reduce the mortality. Traditional method for detection of CAN uses Ewing's algorithm where five noninvasive cardiovascular tests are used. Often for clinician, it is difficult to collect data from for the Ewing Battery patients due to onerous test conditions. In this paper, we propose a hybrid of wrapper-filter approach to find novel features from patients' ECG records and then generate decision rules for the new features for easier detection of CAN. In the proposed feature selection, a hybrid of filter (Maximum Relevance, MR) and wrapper (Artificial Neural Net Input Gain Measurement Approximation ANNIGMA) approaches (MR-ANNIGMA) would be used. The combined heuristics in the hybrid MRANNIGMA takes the advantages of the complementary properties of the both filter and wrapper heuristics and can find significant features. The selected features set are used to generate a new set of rules for detection of CAN. Experiments on real patient records shows that proposed method finds a smaller set of features for detection of CAN than traditional method which are clinically significant and could lead to an easier way to diagnose CAN. © 2010 IEEE.
AWSum - applying data mining in a health care scenario
- Authors: Quinn, Anthony , Jelinek, Herbert , Stranieri, Andrew , Yearwood, John
- Date: 2008
- Type: Text , Conference paper
- Relation: Paper presented at International Conference on Intelligent Sensors, Sensor Networks and Information Processing, ISSNIP 2008, Sydney, New South Wales : 15th-18th December 2008 p. 291-296
- Full Text:
- Description: This paper investigates the application of a new data mining algorithm called Automated Weighted Sum, (AWSum), to diabetes screening data to explore its use in providing researchers with new insight into the disease and secondarily to explore the potential the algorithm has for the generation of prognostic models for clinical use. There are many data mining classifiers that produce high levels of predictive accuracy but their application to health research and clinical applications is limited because they are complex, produce results that are difficult to interpret and are difficult to integrate with current knowledge and practises. This is because most focus on accuracy at the expense of informing the user as to the influences that lead to their classification results. By providing this information on influences a researcher can be pointed to new potentially interesting avenues for investigation. AWSum measures influence by calculating a weight for each feature value that represents its influence on a class value relative to other class values. The results produced, although on limited data, indicated the approach has potential uses for research and has some characteristics that may be useful in the future development of prognostic models.
- Description: 2003006660
Detection of CAN by ensemble classifiers based on Ripple Down rules
- Authors: Kelarev, Andrei , Dazeley, Richard , Stranieri, Andrew , Yearwood, John , Jelinek, Herbert
- Date: 2012
- Type: Text , Book chapter
- Relation: Knowledge Management and Acquisition for Intelligent Systems p. 147-159
- Full Text: false
- Reviewed:
- Description: It is well known that classification models produced by the Ripple Down Rules are easier to maintain and update. They are compact and can provide an explanation of their reasoning making them easy to understand for medical practitioners. This article is devoted to an empirical investigation and comparison of several ensemble methods based on Ripple Down Rules in a novel application for the detection of cardiovascular autonomic neuropathy (CAN) from an extensive data set collected by the Diabetes Complications Screening Research Initiative at Charles Sturt University. Our experiments included essential ensemble methods, several more recent state-of-the-art techniques, and a novel consensus function based on graph partitioning. The results show that our novel application of Ripple Down Rules in ensemble classifiers for the detection of CAN achieved better performance parameters compared with the outcomes obtained previously in the literature.
A comparison of machine learning algorithms for multilabel classification of CAN
- Authors: Kelarev, Andrei , Stranieri, Andrew , Yearwood, John , Jelinek, Herbert
- Date: 2012
- Type: Text , Journal article
- Relation: Advances in Computer Science and Engineering Vol. 9, no. 1 (2012), p. 1-4
- Full Text:
- Reviewed:
- Description: This article is devoted to the investigation and comparison of several important machine learning algorithms in their ability to obtain multilabel classifications of the stages of cardiac autonomic neuropathy (CAN). Data was collected by the Diabetes Complications Screening Research Initiative at Charles Sturt University. Our experiments have achieved better results than those published previously in the literature for similar CAN identification tasks.
Rule-based classifiers and meta classifiers for identification of cardiac autonomic neuropathy progression
- Authors: Jelinek, Herbert , Kelarev, Andrei , Stranieri, Andrew , Yearwood, John
- Date: 2012
- Type: Text , Journal article
- Relation: International Journal of Information Science and Computer Mathematics Vol. 5, no. 2 (2012), p. 49-53
- Full Text:
- Reviewed:
- Description: We investigate and compare several rule-based classifiers and meta classifiers in their ability to obtain multi-class classifications of cardiac autonomic neuropathy (CAN) and its progression. The best results obtained in our experiments are significantly better than the outcomes published previously in the literature for analogous CAN identification tasks or simpler binary classification tasks.
Empirical investigation of consensus clustering for large ECG data sets
- Authors: Kelarev, Andrei , Stranieri, Andrew , Yearwood, John , Jelinek, Herbert
- Date: 2012
- Type: Text , Conference proceedings
- Full Text: false
- Description: This article investigates a novel machine learning approach applying consensus clustering in conjunction with classification for the data mining of very large and highly dimensional ECG data sets. To obtain robust and stable clusterings, consensus functions can be applied for clustering ensembles combining a multitude of independent initial clusterings. Direct applications of consensus functions to highly dimensional ECG data sets remain computationally expensive and impracticable. We introduce a multistage scheme including various procedures for dimensionality reduction, consensus clustering of randomized samples, followed by the use of a fast supervised classification algorithm. Applying the Hybrid Bipartite Graph Formulation combined with rank ordering and SMO we obtained an area under the receiver operating curve of 0.987. The performance of the classification algorithm at the final stage is crucial for the effectiveness of this technique. It can be regarded as an indication of the reliability, quality and stability of the combined consensus clustering. © 2012 IEEE.
Empirical study of decision trees and ensemble classifiers for monitoring of diabetes patients in pervasive healthcare
- Authors: Kelarev, Andrei , Stranieri, Andrew , Yearwood, John , Jelinek, Herbert
- Date: 2012
- Type: Text , Conference proceedings
- Full Text: false
- Description: Diabetes is a condition requiring continuous everyday monitoring of health related tests. To monitor specific clinical complications one has to find a small set of features to be collected from the sensors and efficient resource-aware algorithms for their processing. This article is concerned with the detection and monitoring of cardiovascular autonomic neuropathy, CAN, in diabetes patients. Using a small set of features identified previously, we carry out an empirical investigation and comparison of several ensemble methods based on decision trees for a novel application of the processing of sensor data from diabetes patients for pervasive health monitoring of CAN. Our experiments relied on an extensive database collected by the Diabetes Complications Screening Research Initiative at Charles Sturt University and concentrated on the particular task of the detection and monitoring of cardiovascular autonomic neuropathy. Most of the features in the database can now be collected using wearable sensors. Our experiments included several essential ensemble methods, a few more advanced and recent techniques, and a novel consensus function. The results show that our novel application of the decision trees in ensemble classifiers for the detection and monitoring of CAN in diabetes patients achieved better performance parameters compared with the outcomes obtained previously in the literature. © 2012 IEEE.
- Description: 2003009675
Improving classifications for cardiac autonomic neuropathy using multi-level ensemble classifiers and feature selection based on random forest
- Authors: Kelarev, Andrei , Stranieri, Andrew , Abawajy, Jemal , Yearwood, John , Jelinek, Herbert
- Date: 2012
- Type: Text , Conference paper
- Relation: Tenth Australasian Data Mining Conference Vol. 134, p. 93-101
- Full Text: false
- Reviewed:
- Description: This paper is devoted to empirical investigation of novel multi-level ensemble meta classifiers for the detection and monitoring of progression of cardiac autonomic neuropathy, CAN, in diabetes patients. Our experiments relied on an extensive database and concentrated on ensembles of ensembles, or multi-level meta classifiers, for the classification of cardiac autonomic neuropathy progression. First, we carried out a thorough investigation comparing the performance of various base classifiers for several known sets of the most essential features in this database and determined that Random Forest significantly and consistently outperforms all other base classifiers in this new application. Second, we used feature selection and ranking implemented in Random Forest. It was able to identify a new set of features, which has turned out better than all other sets considered for this large and well-known database previously. Random Forest remained the very best classifier for the new set of features too. Third, we investigated meta classifiers and new multi-level meta classifiers based on Random Forest, which have improved its performance. The results obtained show that novel multi-level meta classifiers achieved further improvement and obtained new outcomes that are significantly better compared with the outcomes published in the literature previously for cardiac autonomic neuropathy.
AWSum -Combining classification with knowledge acquisition
- Authors: Quinn, Anthony , Stranieri, Andrew , Yearwood, John , Hafen, Gaudenz , Jelinek, Herbert
- Date: 2008
- Type: Text , Journal article
- Relation: International Journal of Software and Informatics Vol. 2, no. 2 (2008), p. 199-214
- Full Text: false
- Reviewed:
- Description: Many classifiers achieve high levels of accuracy but have limited applicability in real world situations because they do not lead to a greater understanding or insight into the way features influence the classification. In areas such as health informatics a classifier that clearly identifies the influences on classification can be used to direct research and formulate interventions. This research investigates the practical aplications of Automated Weighted Sum, (AWSum), a classifier that provides accuracy comparable to other techniques whist providing insight into the data. This is achieved by calculating a weight for each feature value that represents its influence on the class value. The merits of this approach in classification and insight are evaluated on a Cystic Fibrosis and diabetes datasets with positive results.