A survey of early-career researchers in Australia
- Authors: Christian, Katherine , Johnstone, Carolyn , Larkins, Jo-ann , Wright, Wendy , Doran, Michael
- Date: 2021
- Type: Text , Journal article
- Relation: eLife Vol. 10, no. (2021), p. 1-19
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- Description: Early-career researchers (ECRs) make up a large portion of the academic workforce and their experiences often reflect the wider culture of the research system. Here we surveyed 658 ECRs working in Australia to better understand the needs and challenges faced by this community. Although most respondents indicated a ‘love of science’, many also expressed an intention to leave their research position. The responses highlight how job insecurity, workplace culture, mentorship and ‘questionable research practices’ are impacting the job satisfaction of ECRs and potentially compromising science in Australia. We also make recommendations for addressing some of these concerns. © Christian et al.
Observations of caregiver supervision of children at beaches : Identification of factors associated with high supervision
- Authors: Petrass, Lauren , Blitvich, Jennifer , Finch, Caroline
- Date: 2011
- Type: Text , Journal article
- Relation: Injury Prevention Vol. 17, no. 4 (2011), p. 244-249
- Relation: http://purl.org/au-research/grants/nhmrc/565900
- Relation: http://purl.org/au-research/grants/nhmrc/565904
- Full Text: false
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- Description: Objective: To identify independent factors associated with caregiver supervision levels at beaches. Methods: Children (aged 1-14 years) engaged in beach play and their caregivers were observed at Australian beaches during September-April, 2008/09. Caregiver, child, and environmental factor data were collected and recorded on a validated observation instrument. The main outcome of interest was a continuous measure of supervision. After adjusting for potential clustering by beach/state, multivariable linear regression was used to identify independent factors associated with caregiver supervision. Results: Four independent predictors of supervision and one interaction effect (child age by the caregiver and child position on beach) were identified. Caregivers who were supervising from a different position to where the child was playing were less likely to provide high supervision, as were older caregivers (>35 years) compared to younger caregivers (≤34 years). Compared to children playing alone, children playing with one, or two or more others were less likely to receive high supervision, and children aged 1-4 years were likely to receive higher supervision than older children. Conclusion: This study provides new knowledge about underlying factors associated with the level of caregiver supervision in beach settings. Future studies should continue to explore independent predictors of supervision so that effective programmes, which focus on caregiver supervision, can be targeted to address poor supervision practices.
The impact of prostate cancer on partners: A qualitative exploration
- Authors: Wootten, Addie , Abbott, Jo-Anne , Osborne, Dawn , Austin, David , Klein, Britt , Costello, Anthony , Murphy, Declan
- Date: 2014
- Type: Text , Journal article
- Relation: Psycho-Oncology Vol. 23, no. 11 (2014), p. 1252-1258
- Full Text: false
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- Description: Objective: Prostate cancer and its treatment can result in numerous physical and psychological morbidities for the patient as well as his partner. This qualitative study aimed to explore the experiences of intimate spouses or partners of men diagnosed and/or treated for prostate cancer to better understand the personal impact of prostate cancer on the partner. Methods: Twenty-seven partners participated in this study. Six focus groups were convened, and one in-depth interview was undertaken to explore the practical impact of prostate cancer on the intimate spouse/partner. All discussions were audio-recorded and transcribed and then coded using a thematic approach. Results: Six themes emerged: (a) The influence of the man's response to prostate cancer on the partner, (b) The need to be involved in treatment and medical decision making, (c) Supporting a man who is experiencing a loss of masculinity, (d) Degree of congruence between each partner's coping responses, (e) Constrained communication, and (f) Changed roles and increased practical management. Conclusions: It is clear that prostate cancer impacts substantially on many areas of partner well-being. An effective intervention provided to this population seems warranted and may lead to improvements in partner well-being, assist the couple in lessening the impact of prostate cancer and its treatment on their relationship, and assist in the man's recovery. © 2014 John Wiley & Sons, Ltd.
A prospective study of coping and adjustment in adolescents with craniofacial conditions
- Authors: Roberts, Rachel , Shute, Rosalyn
- Date: 2012
- Type: Text , Journal article
- Relation: Children's Health Care Vol. 41, no. 2 (2012), p. 111-128
- Full Text: false
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- Description: This study aimed to examine the role of coping strategy use in concurrent and later adjustment in adolescents with craniofacial anomalies (CFAs). It was expected that better adjustment at both baseline and 12 months would be related to greater baseline perceived coping efficacy, greater use of active coping and social support seeking, and less use of avoidance strategies. Eighty adolescents with CFAs and their parents completed measures of adjustment, coping strategy use, and efficacy in response to CFA-related stressful situations. Fifty-five families completed these measures again 12 months later. Overall, the predicted pattern of correlations between coping and adjustment was found. However, coping and efficacy at baseline did not explain a significant proportion of the variance in adjustment measures 1 year later, after controlling for baseline adjustment. Such prospective findings are beginning to bring into question the assumed importance of coping in pediatric adjustment. © 2012 Copyright Taylor and Francis Group, LLC.
Is there a role for rare variants in DRD4 gene in the susceptibility for ADHD Searching for an effect of allelic heterogeneity
- Authors: Tovo-Rodrigues, Luciana , Rohde, Luis , Roman, Tatiana , Schmitz, Marcelo , Polanczyk, Guilherme , Zeni, Cristian , Marques, Francine , Contini, Veronica , Grevet, Eugenio , Belmonte-De-Abreu, Paulo , Bau, Claiton , Hutz, Mara
- Date: 2012
- Type: Text , Journal article
- Relation: Molecular Psychiatry Vol. 17, no. 5 (May 2012), p. 520-526
- Full Text: false
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- Description: Although several studies have demonstrated an association between the 7-repeat (7R) allele in the 48-bp variable number of tandem repeats (VNTRs) in the exon 3 at dopamine receptor D4 (DRD4) gene and attention-deficit/ hyperactivity disorder (ADHD), others failed to replicate this finding. In this study, a total of 786 individuals with ADHD were genotyped for DRD4 exon 3 VNTR. All 7R homozygous subjects were selected for VNTR re-sequencing. Subjects homozygous for the 4R allele were selected paired by age, ancestry and disorder subtypes in order to have a sample as homogeneous as possible with 7R/7R individuals. Using these criteria, 103 individuals (66 with ADHD and 37 control individuals) were further investigated. An excess of rare variants were observed in the 7R alleles of ADHD patient when compared with controls (P = 0.031). This difference was not observed in 4R allele. Furthermore, nucleotide changes that predict synonymous and non-synonymous substitutions were more common in the 7R sample (P = 0.008 for total substitutions and P = 0.043 for non-synonymous substitutions). In silico prediction of structural/functional alterations caused by these variants have also been observed. Our findings suggest that not only repeat length but also DNA sequence should be assessed to better understand the role of DRD4 exon 3 VNTR in ADHD genetic susceptibility.
- Description: C1
Statistical modelling of falls count data with excess zeros
- Authors: Khan, Asaduzzaman , Ullah, Shahid , Nitz, Jenny
- Date: 2011
- Type: Text , Journal article
- Relation: Injury Prevention Vol. 17, no. 4 (2011), p. 266-270
- Full Text: false
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- Description: Objective To examine the appropriateness of different statistical models in analysing falls count data. Methods Six count models (Poisson, negative binomial (NB), zero-inflated Poisson (ZIP), zero-inflated NB (ZINB), hurdle Poisson (HP) and hurdle NB (HNB)) were used to analyse falls count data. Empirical evaluation of the competing models was performed using model selection criteria and goodness-of-fit through simulation. Data used were from a prospective cohort study of women aged 40-80 years. Results Of the 465 women analysed, 330 (71%) did not fall at all. The analyses identified strong evidence of overdispersion in the falls data. The NB-based regression models (HNB, ZINB, NB) were better performed than the Poisson-based regression models (Poisson, ZIP, HP). Vuong tests favoured the HNB model over the NB and ZINB models and the NB model over the ZINB model. Model accuracy measures and Monte Carlo simulation of goodness-of-fit confirmed the lack of fit of the Poissonbased regression models and demonstrated the best fit for the HNB model with comparable good fit for the ZINB and NB models. Conclusions Falls count data consisting of a considerable number of zeros can be appropriately modelled by the NBbased regression models, with the HNB model offering he best fit. The evaluation procedure presented in this aper provides a defensible guideline to appropriately odel falls or similar count data with excess zeros.
Emotional functioning in children and adolescents with elevated depressive symptoms
- Authors: Hughes, Elizabeth , Gullone, Eleonora , Watson, Shaun
- Date: 2011
- Type: Text , Journal article
- Relation: Journal of Psychopathology and Behavioral Assessment Vol. 33, no. 3 (2011), p. 335-345
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- Description: Difficulties with emotion and its regulation are of central importance to the etiology and course of depression. The current study investigated these constructs in relation to childhood and adolescence by comparing the emotional functioning of 170 9- to 15-year-olds reporting high levels of depressive symptoms (HD) to a matched sample of 170 children and adolescents reporting low levels of depressive symptoms (LD). Compared to LD, HD participants reported significantly greater shame proneness, poorer functioning on emotion regulation competencies (emotional control, self-awareness and situational responsiveness), less healthy emotion regulation strategy use (less reappraisal and greater suppression), and lower levels of guilt proneness. Empathic concern did not differ between the two groups. The findings enhance current knowledge by providing a more comprehensive profile of the emotional difficulties experienced by children and adolescents with elevated depressive symptoms. © 2011 Springer Science+Business Media, LLC.
Legal risk management and injury in the fitness industry: the outcomes of focus group research and a national survey of fitness professionals
- Authors: Keyzer, Patrick , Coyle, Ian , Dietrich, Joachim , Norton, Kevin , Sekendiz, Betul , Jones, Veronica , Finch, Caroline
- Date: 2014
- Type: Text , Journal article
- Relation: Journal of Law and Medicine Vol. 21, no. 4 (June 2014 2014), p. 826-844
- Full Text: false
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- Description: The Australian Fitness Industry Risk Management (AFIRM) Project was set up to explore the operation of rules and regulations for the delivery of safe fitness services. This article summarises the results of recent focus group research and a national survey of risk management practices by the AFIRM Project. Our focus group research in four States identified the following most important concerns: (1) the competency of fitness professionals; (2) the effectiveness of pre-exercise screening and the management of de-conditioned clients; (3) poor supervision of fitness service users and incorrect use of equipment; (4) fitness trainers failing to remain within their scope of practice; (5) equipment misuse (as distinct from incorrect use); and (6) poor fitness training environments. This information was then used to develop 45 specific items for a questionnaire that was disseminated throughout the fitness industry. The survey, which is the largest ever conducted in the Australian fitness industry (n = 1,178), identified similar concerns. Our research indicates that efforts to improve risk management in the fitness industry should focus, first and foremost, on the development and monitoring of safety policy, and improvements in the education and training of fitness instructors to ensure that they can incorporate risk management practices.
- Description: C1
Oppositional defiant disorder: Prevalence based on parent and teacher ratings of Malaysian primary school children
- Authors: Gomez, Rapson , Hafetz, Nina , Gomez, Rashika
- Date: 2013
- Type: Text , Journal article
- Relation: Asian Journal of Psychiatry Vol. 6, no. 4 (2013), p. 299-302
- Full Text: false
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- Description: Background: This study examined the prevalence rate of Oppositional Defiant Disorder (ODD) in Malaysian primary school children. Methods: In all 934 Malaysian parents and teachers completed ratings of their children using a scale comprising DSM-IV-TR ODD symptoms. Results: Results showed rates of 3.10%, 3.85%, 7.49% and 0.64% for parent, teacher, parent or teacher ("or-rule"), and parent and teacher ("and-rule") ratings, respectively. When the functional impairment criterion was not considered, the rate reported by parents was higher at 13.28%. Discussion: The theoretical, diagnostic and cultural implications of the findings are discussed. © 2013 Elsevier B.V.
- Description: C1
Living with a craniofacial condition : Development of the Craniofacial Experiences Questionnaire (CFEQ) for adolescents and their parents
- Authors: Roberts, Rachel , Shute, Rosalyn
- Date: 2011
- Type: Text , Journal article
- Relation: Cleft Palate-Craniofacial Journal Vol. 48, no. 6 (2011), p. 727-735
- Full Text: false
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- Description: Objective: To develop a new instrument (the Craniofacial Experiences Questionnaire, CFEQ) to measure both stressors and positive aspects of living with a craniofacial condition from adolescent and parent perspectives, and to examine its validity and reliability. A secondary aim was to explore experiences reported according to age, gender, and diagnosis. Design: Self-report and parent report questionnaires (CFEQ, Youth Self Report [YSR], Child Behavior Checklist [CBCL], Behavioral and Emotional Rating Scale [BERS]) were completed by adolescents with congenital craniofacial conditions and their parents. Participants: Fifty adolescents with craniofacial conditions and 55 of their parents. Results: Internal reliability of the stressor and positive aspects scales was acceptable (.81 to .92) but was lower for some stressor subscales (.50-.86). Higher stressor scale scores were related to poorer adjustment (CBCL r = .55, YSR r = .37). There were no consistent differences in the stressful or positive experiences of young people with craniofacial conditions according to gender or age. There were no differences in stressors reported according to diagnosis. Conclusions: The CFEQ shows promise as a clinical and research tool for investigating the stressors and positive experiences of young people with craniofacial conditions. Consistent with the literature on chronic pediatric conditions, there were few differences in experiences of young people according to diagnosis. Furthermore, the lack of gender or age differences supports the need for clinicians to comprehensively assess the experiences of young people regardless of demographic variables.
Pathway analysis shows association between FGFBP1 and hypertension
- Authors: Tomaszewski, Maciej , Charchar, Fadi , Nelson, Christopher , Barnes, Timothy , Denniff, Matthew , Kaiser, Michael , Debiec, Radoslaw , Christofidou, Paraskevi , Rafelt, Suzanne , Van Harst, Pim Der , Wang, William , Maric, Christine , Zukowska-Szczechowska, Ewa , Samani, Nilesh
- Date: 2011
- Type: Text , Journal article
- Relation: Journal of the American Society of Nephrology Vol. 22, no. 5 (2011), p. 947-955
- Full Text: false
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- Description: Variants in the gene encoding fibroblast growth factor 1 (FGF1) co-segregate with familial susceptibility to hypertension, and glomerular upregulation of FGF1 associates with hypertension. To investigate whether variants in other members of the FGF signaling pathway may also associate with hypertension, we genotyped 629 subjects from 207 Polish families with hypertension for 79 single nucleotide polymorphisms in eight genes of this network. Family-based analysis showed that parents transmitted the major allele of the rs16892645 polymorphism in the gene encoding FGF binding protein 1 (FGFBP1) to hypertensive offspring more frequently than expected by chance (P = 0.005). An independent cohort of 807 unrelated Polish subjects validated this association. Furthermore, compared with normotensive subjects, hypertensive subjects had approximately 1.5- and 1.4-fold higher expression of renal FGFBP1 mRNA and protein (P = 0.04 and P = 0.001), respectively. By immunohistochemistry, hypertensionrelated upregulation of FGFBP1 was most apparent in the glomerulus and juxtaglomerular space. Taken together, these data suggest that FGFBP1 associates with hypertension and that systematic analysis of signaling pathways can identify previously undescribed genetic associations. Copyright © 2011 by the American Society of Nephrology.
The gendered shaping of University Leadership in Australia, South Africa and the United Kingdom
- Authors: White, Kate , Bagilhole, Barbara , Riordan, Sarah
- Date: 2012
- Type: Text , Journal article
- Relation: Higher Education Quarterly Vol. 66, no. 3 (2012), p. 293-307
- Full Text: false
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- Description: This article analyses career trajectories into university management in Australia, South Africa and the United Kingdom (UK), skills required to operate effectively and the power of vice-chancellors (VCs) and their impact on the gendered shaping of university leadership. It is based on qualitative research with 56 male and female senior managers. The research found that the typical career path was modelled on male academic careers. Not surprisingly, in South Africa and the UK the perception of the top university leader was of a man but in Australia, where more women have been VCs, there was no such assumption. Characteristics valued in university leaders in Australia and South Africa were 'soft' leadership traits, but in the UK 'hard' aggressive and competitive leadership prevailed. VCs are enormously powerful and can shape the gender balance in management teams and thereby potentially broadening leadership styles beyond the predominant transactional model to include transformational leadership. © 2012 The Authors. Higher Education Quarterly © 2012 Blackwell Publishing Ltd.
Girls' transition from participation in a modified sport program to club sport competition - A study of longitudinal patterns and correlates
- Authors: Eime, Rochelle , Harvey, Jack , Charity, Melanie
- Date: 2018
- Type: Text , Journal article
- Relation: BMC Public Health Vol. 18, no. 1 (2018), p. 1-7
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- Description: Background: Participation in sport is very popular for young children. Many children participate in entry-level modified sports programs. These programs are modified to match the developmental capacity of children and are aimed at development of fundamental motor skills and sport-specific skills, rather than competition. There is limited research on the longitudinal tracking of children in these programs and into club-based competition. Research suggests that most children drop-out of the sport and do not transition into club-based competition. Furthermore, more females than males drop-out of sport. The aim of this study is to investigate longitudinally, the patterns and demographic predictors of children's transition from modified sport programs to club sport competition for females. Methods: This study analysed sport participation for females in a popular Australian, predominantly female, sport. Players of the modified sports program were followed over 4 years to determine their pattern of transition: transition to junior player status, withdraw from the sport, or continue in the modified program. Pattern of transition was compared across age (4-10), geographical region (metropolitan/non-metropolitan) and socio-economic status (SES). Logistic regression was used to model the effect of the three factors on the likelihood of transition. Results: A total of 13,760 female children (aged 4-10) participated in the modified sport in the first year. The majority (59%) transitioned from the modified sport program and into club competition. However the rate of transition varied with age, residential location and socio-economic status, and there was an interaction between region and SES, with SES having a significant influence on transition in the metropolitan region. The peak sport entry age with the highest rates of transition was 7-9 years. Conclusions: This study demonstrated that whilst the majority of female participants continued participantion and tranisitioned from the modified sport program and into club competition, the strongest correlate of transition was age of entry, with transition rate peaking among those who commenced at age 7-9 years. It is recommended that, in order to maximise continued participation, sport policy and strategic developments should consider the possibility that targeting the very young is not the optimum recruitment strategy for fostering continued sport participation. © 2018 The Author(s).
Neuromuscular dysfunction that may predict ACL injury risk: A case report
- Authors: Saunders, Natalie , McLean, Scott , Fox, Aaron , Otago, Leonie
- Type: Text , Journal article
- Relation: Knee Vol.21, no.(3), p.789-792
- Full Text: false
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The perception of injury risk and safety in triathlon competition: An exploratory focus group study
- Authors: Gosling, Cameron , Donaldson, Alex , Forbes, Andrew , Gabbe, Belinda
- Date: 2013
- Type: Text , Journal article
- Relation: Clinical Journal of Sport Medicine Vol. 23, no. 1 (2013), p. 70-73
- Full Text: false
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- Description: OBJECTIVE:: To explore stakeholder perceptions of triathlon competition safety and injury risk. DESIGN:: Qualitative focus group study. SETTING:: Triathlon stakeholders from Melbourne, Australia. PARTICIPANTS:: Competition organizers, coaches, and competitors of various skill levels, age, gender, and experience (n = 18). INTERVENTIONS:: Focus groups were conducted, recorded, and transcribed for analysis. MAIN OUTCOME MEASURES:: Key themes were identified using content analysis. RESULTS:: The perceived risk of serious injury was highest for cycling. Running was most commonly linked to minor injuries. Physical and environmental factors, including course turning points, funneling of competitors into narrow sections, and the weather, were perceived as contributing to injury. Experience, skill level, feelings of vulnerability, personal awareness, club culture, and gender issues were perceived as the competitor-related factors potentially contributing to injury. The cycling mount/dismount area, cycling, and swim legs were the race sections perceived as the riskiest for competitors. Competition organizers were considered to generally have the competitors' best interest as a priority. Triathlons were acknowledged as risky activities and individual competitors accepted this risk. CONCLUSIONS:: This study has highlighted the main risks and concerns perceived by triathlon competitors, coaches, and competition organizers, which will help identify potential, context-relevant intervention strategies to reduce injury risk. © 2013 by Lippincott Williams & Wilkins.
An evaluation of 'Reach Out Central': An online gaming program for supporting the mental health of young people
- Authors: Shandley, Kerrie , Austin, David , Klein, Britt , Kyrios, Michael
- Date: 2010
- Type: Text , Journal article
- Relation: Health Education Research Vol. 25, no. 4 (2010), p. 563-574
- Full Text: false
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- Description: The objective of this study was to conduct an evaluation of Reach Out Central (ROC), an online gaming program designed to support the mental health of people aged 16-25. The evaluation sought to determine the benefit of playing ROC on alcohol use, use of coping strategies, psychological distress, resilience and satisfaction with life. Changes in mental health literacy, mental health stigma and willingness to seek help and program satisfaction were also investigated. A single group (N=266) quasi-experimental repeated measures (pre-, post-program, 2-month follow-up) design was employed. The results demonstrated positive improvements across all outcome measures for females; however, a non-significant worsening effect was observed for males on seeking support, avoidance and resilience. Improvements for both genders were observed on mental health literacy and help-seeking. However, literacy levels and help-seeking were significantly higher, and stigma significantly lower for females. Program satisfaction ratings were high irrespective of gender. Although some inconsistencies between genders were noted, ROC appears to enhance protective factors for the prevention or early intervention of mental health disorders. The results of this study need to be viewed with its limitations in mind, specifically, the use of an open trial methodology and the small number of male participants. © The Author 2009. Published by Oxford University Press. All rights reserved.
Chiropractic Observation and Analysis Study (COAST): Providing an understanding of current chiropractic practice
- Authors: French, Simon , Charity, Melanie , Forsdike, Kirsty , Gunn, Jane , Polus, Barbara , Walker, Bruce , Chondros, Patty , Britt, Helena
- Date: 2013
- Type: Text , Journal article
- Relation: Medical Journal of Australia Vol. 199, no. 10 (2013), p. 687-691
- Full Text: false
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- Description: Objectives: COAST (Chiropractic Observation and Analysis Study) aimed to describe the clinical practices of chiropractors in Victoria, Australia. Design: Cross-sectional study using the BEACH (Bettering the Evaluation and Care of Health) methods for general practice. Setting and participants: 180 chiropractors in active clinical practice in Victoria were randomly selected from the list of 1298 chiropractors registered on Chiropractors Registration Board of Victoria. Twenty-four chiropractors were ineligible, 72 agreed to participate, and 52 completed the study. Main outcome measures: Each participating chiropractor documented encounters with up to 100 consecutive patients. For each chiropractor-patient encounter, information collected included patient health profile, patient reasons for encounter, problems and diagnoses, and chiropractic care. Results: Data were collected on 4464 chiropractor-patient encounters from 52 chiropractors between 11 December 2010 and 28 September 2012. In most (71%) encounters, patients were aged 25-64 years; 1% of encounters were with infants (age < 1 year; 95% CI, 0.3%-3.2%). Musculoskeletal reasons for encounter were described by patients at a rate of 60 per 100 encounters (95% CI, 54-67 encounters) and maintenance and wellness or check-up reasons were described at a rate of 39 per 100 encounters (95% CI, 33-47 encounters). Back problems were managed at a rate of 62 per 100 encounters (95% CI, 55-71 encounters). The most frequent care provided by the chiropractors was spinal manipulative therapy and massage. Conclusions: A range of conditions are managed by chiropractors in Victoria, Australia, but most commonly these conditions are musculoskeletal-related. These results can be used by stakeholders of the chiropractic profession in workforce development, education and health care policy.
Testing the NKT cell hypothesis in lenalidomide-treated myelodysplastic syndrome patients
- Authors: Chan, Angela , Neeson, Paul , Leeansyah, Edwin , Tainton, K. , Quach, Hang , Prince, Henry , Godfrey, Dale , Ritchie, David , Berzins, Stuart
- Date: 2010
- Type: Text , Journal article
- Relation: Leukemia Vol. 24, no. 3 (2010), p. 592-600
- Full Text: false
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- Description: Myelodysplastic syndrome (MDS) comprises a group of clonal bone marrow disorders characterized by ineffective hematopoiesis and increased predisposition to acute myeloid leukemia. The causes of MDS remain poorly defined, but several studies have reported the NKT cell compartment of patients with MDS is deficient in number and functionally defective. In support of a central role for NKT cells, a pilot clinical study reported that lenalidomide (an approved treatment for MDS) increased NKT cell numbers in patients with MDS, and several in vitro studies showed lenalidomide specifically promoted NKT cell proliferation and cytokine production. We tested this in a much larger study and confirm a moderate in vitro augmentation of some NKT cell functions by lenalidomide, but find no impact on the NKT cell compartment of patients treated with lenalidomide, despite a consistently positive clinical response. We further show that the frequency and cytokine production of NKT cells is normal in patients with MDS before treatment and remains stable throughout 10 months of lenalidomide therapy. Collectively, our data challenge the concept that NKT cell defects contribute to the development of MDS, and show that a clinical response to lenalidomide is not dependent on modulation of NKT cell frequency or function. © 2010 Macmillan Publishers Limited All rights reserved.
Injury epidemiology among Australian female cricketers
- Authors: Perera, Nirmala
- Date: 2016
- Type: Text , Thesis , PhD
- Full Text:
- Description: Cricket is a male-dominated sport; however, its popularity among females is increasing. Like other sports, participation in cricket poses the risk of injury to players. Injury problems for female cricketers are virtually unknown, as studies examining cricket injuries include almost exclusively male participants. In other sports, the types of injuries experienced by men and women are known to be different. Therefore, a clear understanding of the extent and types of injuries sustained by female cricket players is required, to underpin appropriately targeted injury prevention strategies. This thesis provides the first detailed epidemiological profile of cricket injuries sustained by women, by: 1. conducting a systematic review describing injuries in competitive team bat or stick sports in women, to enable cricket injuries to be viewed within the perspective of wider, but relevant, injury data, 2. evaluating existing data sources relating to hospital admissions from Victoria and Queensland and successful insurance claims across Australia, 3. examining the nature and incidence of cricket injuries in elite female players using Cricket Australia’s Athlete Management System, and 4. conducting a nationwide self-report survey of injuries during the 2014–15 season. This PhD research represents participants from different levels of play, across age groups and across Australia. The findings indicate that incidence of injuries for female cricketers were higher than expected based on previous findings in comparable sports, except when considered in relation to insurance claims. The cricket injury rate across hospital presentations, insurance claims, the AMS (Fair Play AMS 2016) and self-reported survey data, each of which represents different level of the sports injury pyramid, identified all-rounders and pace bowlers as having a higher incidence of injury than players in other positions. The highest frequency of reported injuries were in the head, hands, knees and ankles. The nature of the most common injuries were dislocations/sprains/strains, fractures, muscle injury, joint injury and gradual onset injuries. At the elite-level, lumber spine stress fractures accounted for a significant amount of time-loss from the sport. In this thesis, findings from the insurance claims, self-reported survey and AMS (Fair Play AMS 2016) data indicated that most injuries were of a low severity and were more likely to be treated outside of healthcare facilities such as hospitals. In summary, patterns of the most common injuries, in terms of anatomical location and nature of the injuries, were consistent throughout community-level players with some similarities to elite-level players. However, the injury mechanisms and risk factors may differ depending on the level of competition and player’s skill. Recommendations are that ongoing injury surveillance should be conducted at all levels of the sport, and surveillance methodology should be tailored to the specific setting, personnel and available resources. Therefore, before implementing an injury surveillance system at the community-level of the sport, more research is needed to fully understand what type of injury surveillance system might be feasible and suitable in this context.
- Description: Doctor of Philosophy
Greater understanding of normal hip physical function may guide clinicians in providing targeted rehabilitation programmes
- Authors: Kemp, Joanne , Schache, Anthony , Makdissi, Michael , Sims, Kevin , Crossley, Kay
- Date: 2013
- Type: Text , Journal article
- Relation: Journal of Science and Medicine in Sport Vol. 16, no. 4 (2013), p. 292-296
- Full Text: false
- Reviewed:
- Description: Objectives: This study investigated tests of hip muscle strength and functional performance. The specific objectives were to: (i) establish intra- and inter-rater reliability; (ii) compare differences between dominant and non-dominant limbs; (iii) compare agonist and antagonist muscle strength ratios; (iv) compare differences between genders; and (v) examine relationships between hip muscle strength, baseline measures and functional performance. Design: Reliability study and cross-sectional analysis of hip strength and functional performance. Methods: In healthy adults aged 18-50. years, normalised hip muscle peak torque and functional performance were evaluated to: (i) establish intra-rater and inter-rater reliability; (ii) analyse differences between limbs, between antagonistic muscle groups and genders; and (iii) associations between strength and functional performance. Results: Excellent reliability (intra-rater ICC = 0.77-0.96; inter-rater ICC = 0.82-0.95) was observed. No difference existed between dominant and non-dominant limbs. Differences in strength existed between antagonistic pairs of muscles: hip abduction was greater than adduction (p < 0.001) and hip ER was greater than IR (p < 0.001). Men had greater ER strength (p = 0.006) and hop for distance (p < 0.001) than women. Strong associations were observed between measures of hip muscle strength (except hip flexion) and age, height, and functional performance. Conclusions: Deficits in hip muscle strength or functional performance may influence hip pain. In order to provide targeted rehabilitation programmes to address patient-specific impairments, and determine when individuals are ready to return to physical activity, clinicians are increasingly utilising tests of hip strength and functional performance. This study provides a battery of reliable, clinically applicable tests which can be used for these purposes. © 2012 Sports Medicine Australia.