Showing items 81 - 100 of 376

Your selections:

Using historical tropical cyclone climate datasets to examine wind speed recurrence for coastal Australia

  • Authors: Bell, Samuel , Dowdy, Andrew , Ramsay, H. , Chand, Savin , Su, C. , Ye, Harvey
  • Date: 2022
  • Type: Text , Journal article
  • Relation: Scientific Reports Vol. 12, no. 1 (2022), p.
  • Full Text:
  • Reviewed:
  • Description: Likelihood estimates of extreme winds, including those from tropical cyclones (TCs) at certain locations are used to inform wind load standards for structural design. Here, wind speed average recurrence intervals (ARIs) determined from TC climate data dating back to the 1970s in two quantile–quantile adjusted reanalysis datasets (ERA5 and BARRA [1990]), and best-track observations for context, were compared with Standardized ARIs (AS/NZS) across seven tropical and two subtropical Australian inland coastal regions. The novelty of this work lies in determining TC-wind speed ARIs from a range of datasets that are not typically used to evaluate this metric. Inherent differences between the data used to determine the Standard ARIs (large sample size allow for larger extrapolations; GEV function) and TC data ARIs (smaller sample size and less certain data; the more asymptotic Lognormal/Weibull functions are used) led to the use of different extreme value functions. Results indicated that although these are two distinct ways of determining design wind speeds, when they are considered equivalent, there was a moderate reproduction of the ARI curves with respect to the Standard in both reanalysis datasets, suggesting that similar analyses using climate model products can provide useful information on these types of metrics with some caveats. Trends in TC wind strength affecting coastal Australia were also analyzed, indicating a potential slight downtrend in tropical West coast TC wind strength and slight uptrend for tropical East coast TC wind strength, noting considerable uncertainty given the short time period and limitations of data quality including over longer time periods. Such trends are not only limited to the relationship between TC intensity and anthropogenic warming, but also to regional changes in TC frequency and track direction. This could lead to significant trends emerging in regional Australian TC wind gust strength before several decades of warming have occurred. It is hoped that climate models can provide both longer-term and a more homogenous base for these types of evaluations and subsequent projections with respect to climate change simulations. © 2022, Crown.

Validating an inertial measurement unit for cricket fast bowling : a first step in assessing the feasibility of diagnosing back injury risk in cricket fast bowlers during a tele-sport-and-exercise medicine consultation

  • Authors: Harnett, Keegan , Plint, Brenda , Chan, Ka , Clark, Benjamin , Netto, Kevin , Davey, Paul , Müller, Sean , Rosalie, Simon
  • Date: 2022
  • Type: Text , Journal article
  • Relation: PeerJ Vol. 10, no. (2022), p.
  • Full Text:
  • Reviewed:
  • Description: This study aimed to validate an array-based inertial measurement unit to measure cricket fast bowling kinematics as a first step in assessing feasibility for tele-sport-and-exercise medicine. We concurrently captured shoulder girdle relative to the pelvis, trunk lateral flexion, and knee flexion angles at front foot contact of eight cricket medium-fast bowlers using inertial measurement unit and optical motion capture. We used one sample t-tests and 95% limits of agreement (LOA) to determine the mean difference between the two systems and Smallest Worth-while Change statistic to determine whether any differences were meaningful. A statistically significant (p < 0.001) but small mean difference of -4.7̊ ± 8.6̊ (95% Confidence Interval (CI) [-3.1̊ to -6.4̊], LOA [-22.2 to 12.7], SWC 3.9̊) in shoulder girdle relative to the pelvis angle was found between the systems. There were no statistically significant differences between the two systems in trunk lateral flexion and knee flexion with the mean differences being 0.1̊ ± 10.8̊ (95% CI [-1.9̊ to 2.2̊], LOA [-22.5 to 22.7], SWC 1.2̊) and 1.6̊ ± 10.1̊ (95% CI [-0.2̊ to 3.3̊], LOA [-19.2 to 22.3], SWC 1.9̊) respectively. The inertial measurement unit-based system tested allows for accurate measurement of specific cricket fast bowling kinematics and could be used in determining injury risk in the context of tele-sport-and-exercise-medicine. Copyright 2022 Harnett et al.

A global-scale screening of non-native aquatic organisms to identify potentially invasive species under current and future climate conditions

  • Authors: Vilizzi, Lorenzo , Copp, Gordon , Hill, Jeffrey , Adamovich, Boris , Lloyd, Lance
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Science of the Total Environment Vol. 788, no. (2021), p.
  • Full Text:
  • Reviewed:
  • Description: The threat posed by invasive non-native species worldwide requires a global approach to identify which introduced species are likely to pose an elevated risk of impact to native species and ecosystems. To inform policy, stakeholders and management decisions on global threats to aquatic ecosystems, 195 assessors representing 120 risk assessment areas across all six inhabited continents screened 819 non-native species from 15 groups of aquatic organisms (freshwater, brackish, marine plants and animals) using the Aquatic Species Invasiveness Screening Kit. This multi-lingual decision-support tool for the risk screening of aquatic organisms provides assessors with risk scores for a species under current and future climate change conditions that, following a statistically based calibration, permits the accurate classification of species into high-, medium- and low-risk categories under current and predicted climate conditions. The 1730 screenings undertaken encompassed wide geographical areas (regions, political entities, parts thereof, water bodies, river basins, lake drainage basins, and marine regions), which permitted thresholds to be identified for almost all aquatic organismal groups screened as well as for tropical, temperate and continental climate classes, and for tropical and temperate marine ecoregions. In total, 33 species were identified as posing a ‘very high risk’ of being or becoming invasive, and the scores of several of these species under current climate increased under future climate conditions, primarily due to their wide thermal tolerances. The risk thresholds determined for taxonomic groups and climate zones provide a basis against which area-specific or climate-based calibrated thresholds may be interpreted. In turn, the risk rankings help decision-makers identify which species require an immediate ‘rapid’ management action (e.g. eradication, control) to avoid or mitigate adverse impacts, which require a full risk assessment, and which are to be restricted or banned with regard to importation and/or sale as ornamental or aquarium/fishery enhancement. © 2021 The Authors. **Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Lance Lloyd" is provided in this record**

An annotated catalog of Iranian Symphypleona and Neelipleona (Hexapoda: Collembola) : new records and key to species

  • Authors: Mayvan, Mahmood , Sadeghi-Namaghi, Hussein , Shayanmehr, Masoumeh , Greenslade, Penelope
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Journal of Asia-Pacific Biodiversity Vol. 14, no. 4 (2021), p. 501-513
  • Full Text:
  • Reviewed:
  • Description: This article provides an annotated catalog of the Symphypleona and Neelipleona (Hexapoda: Collembola) of Iran based on published literature and specimens recently collected from three different ecosystems in North Khorasan province (Forest, Rangeland, and Agricultural) of the years 2018 and 2019. Thirty-five species in seven families and 17 genera are listed. Among them, Megalothorax minimus and Bourletiella sp. are recorded for the first time from Iran. An updated key to the Iranian species and information on the biology and geographical distribution of each species is provided. © 2021 National Science Museum of Korea (NSMK) and Korea National Arboretum (KNA)

An empirical analysis of sediment export dynamics from a constructed landform in the wet tropics

  • Authors: Yavari, Shahla , McIntyre, Neil , Baumgartl, Thomas
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Water (Switzerland) Vol. 13, no. 8 (2021), p.
  • Full Text:
  • Reviewed:
  • Description: Although plot-scale erosion experiments are numerous, there are few studies on constructed landforms. This limits the understanding of their long-term stability, which is especially important for planning mined land rehabilitation. The objective of this study was to gain insight into the erosion processes in a 30 × 30 m trial plot on a mine waste rock dump in tropical northern Australia. The relationships between rainfall, runoff and suspended and bedload sediment export were assessed at annual, seasonal, inter-event and intra-event timescales. During a five-year study period, 231 rainfall– runoff–sediment export events were examined. The measured bedload and suspended sediments (mainly represented in nephelometric turbidity units (NTU)) showed the dominance of the wet season and heavy rainfall events. The bedload dominated the total mass, although the annual bedload diminished by approximately 75% over the five years, with greater flow energy required over time to mobilise the same bedload. The suspended load was more sustained, though it also exhibited an exhaustion process, with equal rainfall and runoff volumes and intensities, leading to lower NTU values over time. Intra-event NTU dynamics, including runoff-NTU time lags and hysteretic behaviours, were somewhat random from one event to the next, indicating the influence of the antecedent distribution of mobilisable sediments. The value of the results for supporting predictive modelling is discussed. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Analysis of water quantity and quality trade-offs to inform selective harvesting of inflows in complex water resource systems

  • Authors: Dey, Sayani , Barton, Andrew , Kandra, Harpreet , Bagirov, Adil , Wilson, Kym
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Water Resources Management Vol. 35, no. 12 (2021), p. 4149-4165
  • Full Text: false
  • Reviewed:
  • Description: Challenges faced by water resource systems are multi-faceted. The problem can be even more pronounced in a dry continent like Australia where the water resources can often be afflicted by high salinity and turbidity. Therefore, modern water resource systems require to appropriately manage both water quality and quantity. This study aims to illustrate the trade-offs between water quantity and quality in a reservoir, based on decisions to harvest different inflow sources. Taylors Lake of the Grampians reservoir system in Western Victoria, Australia was chosen as the case study for this research as it is sufficiently complex and includes many of the contemporary water resources challenges seen around the world. Different operational scenarios were analysed which included increasingly stringent water quality criteria before the water was harvested or otherwise allowed to by-pass the storage. The study suggests that selective harvesting of water can be an option to improve the overall and long-term water quality within a reservoir, but stringent water quality measures can lead to an associated loss of overall water quantity. This research study provides useful insight to water planners and stakeholders in similar catchment settings around the world, to identify water harvesting regimes with competing water quality constraints. © 2021, The Author(s), under exclusive licence to Springer Nature B.V. Correction to: Analysis of Water Quantity and Quality Trade‑Offs to Inform Selective Harvesting of Inflows in Complex Water Resource Systems (Water Resources Management, (2021), 35, 12, (4149-4165), 10.1007/s11269-021-02936-x)

Association between nocturnal activity of the sympathetic nervous system and cognitive dysfunction in obstructive sleep apnoea

  • Authors: Alomri, Ridwan , Kennedy, Gerard , Wali, Siraj , Alhejaili, Faris , Robinson, Stephen
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Scientific Reports Vol. 11, no. 1 (2021), p. 11990-11990.
  • Full Text:
  • Reviewed:
  • Description: Obstructive sleep apnoea (OSA) is associated with repetitive breathing obstructions during sleep. These episodes of hypoxia and associated arousals from sleep induce physiological stress and nocturnal over-activation of the sympathetic nervous system (SNS). One consequence of OSA is impairment in a range of cognitive domains. Previous research into cognitive impairment in OSA have focussed on intermittent hypoxia and disrupted sleep, but not nocturnal over-activation of the SNS. Therefore, we investigated whether nocturnal over-activity of the SNS was associated with cognitive impairments in OSA. The extent of nocturnal SNS activation was estimated from heart rate variability (HRV), pulse wave amplitude (PWA) and stress response biomarkers (cortisol and glucose levels). OSA severity was significantly associated with PWA indices and the HRV low frequency/ high frequency ratio (p < 0.05). Morning blood glucose levels were significantly associated with the duration of a blood oxygen saturation (SaO2) < 90% (p < 0.01). PWA and HRV were significantly associated with the time taken to perform a task involving visuospatial functioning (p < 0.05), but not with impairments in sustained attention, reaction time or autobiographical memory. These results suggest that the visuospatial dysfunction observed in people with OSA is associated with increased nocturnal activity of the SNS. © 2021, The Author(s).

Associations of the initial Covid-19 lockdown on self-reported happiness and worry about developing loneliness : a cross-sectional analysis of rural, regional, and urban Australian communities

  • Authors: Isaac, Vivian , Cheng, Teresa , Townsin, Louise , Assareh, Hassan , Li, Amy , McLachlan, Craig
  • Date: 2021
  • Type: Text , Journal article
  • Relation: International Journal of Environmental Research and Public Health Vol. 18, no. 18 (2021), p.
  • Full Text:
  • Reviewed:
  • Description: Australia adopted hard lockdown measures to eliminate community transmission of COVID-19. Lockdown imposes periods of social isolation that contributes to increased levels of stress, anxiety, depression, loneliness, and worry. We examined whether lockdowns have similar psychosocial associations across rural and urban areas and whether associations existed between happiness and worry of loneliness in the initial wave of the COVID-19 pandemic in Australia. Data were collected using the “COVID-19 Living Survey” between 13 and 20 May 2020 by BehaviourWorks Australia at the Monash Sustainable Development Institute. The mean self-reported feeling of happiness and anxiousness (N = 1593), on a 10-point Likert scale with 0 being least happy or highly anxious, was 6.5 (SD = 2.4) and 3.9 (2.9), respectively. Factors associated with happiness were older age and having a postgraduate education. Participants worried about becoming lonely also exhibited reduced happiness (estimate = −1.58, 95%CI = −1.84–−1.32) and higher anxiousness (2.22, 1.93–2.51) scores, and these conditions remained associated after adjusting for demographics. Interestingly, worry about loneliness was greater in rural areas than in urban communities. The negative impact of the COVID-19 lockdown on rural youth and those less-educated was evident. Participants in rural Australia who were worried about becoming lonely were reportedly less happy than participants in major cities. This dataset provides a better understanding of factors that influence psychological well-being and quality of life in the Australian population and helps to determine whether happiness may be an associative factor that could mitigate self-feelings of anxiety and worry about loneliness. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

AusTraits, a curated plant trait database for the Australian flora

  • Authors: Falster, Daniel , Gallagher, Rachael , Wenk, Elizabeth , Wright, Ian , Cheal, David
  • Date: 2021
  • Type: Text , Journal article , Data article
  • Relation: Scientific Data Vol. 8, no. 1 (2021), p.
  • Full Text:
  • Reviewed:
  • Description: We introduce the AusTraits database - a compilation of values of plant traits for taxa in the Australian flora (hereafter AusTraits). AusTraits synthesises data on 448 traits across 28,640 taxa from field campaigns, published literature, taxonomic monographs, and individual taxon descriptions. Traits vary in scope from physiological measures of performance (e.g. photosynthetic gas exchange, water-use efficiency) to morphological attributes (e.g. leaf area, seed mass, plant height) which link to aspects of ecological variation. AusTraits contains curated and harmonised individual- and species-level measurements coupled to, where available, contextual information on site properties and experimental conditions. This article provides information on version 3.0.2 of AusTraits which contains data for 997,808 trait-by-taxon combinations. We envision AusTraits as an ongoing collaborative initiative for easily archiving and sharing trait data, which also provides a template for other national or regional initiatives globally to fill persistent gaps in trait knowledge. © 2021, The Author(s). **Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “David Cheal" is provided in this record**

Blood–brain barrier disruption and ventricular enlargement are the earliest neuropathological changes in rats with repeated sub-concussive impacts over 2 weeks

  • Authors: Hiles-Murison, Bailey , Lavender, Andrew , Hackett, Mark , Armstrong, Joshua , Nesbit, Michael
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Scientific Reports Vol. 11, no. 1 (2021), p.
  • Full Text:
  • Reviewed:
  • Description: Repeated sub-concussive impact (e.g. soccer ball heading), a significantly lighter form of mild traumatic brain injury, is increasingly suggested to cumulatively alter brain structure and compromise neurobehavioural function in the long-term. However, the underlying mechanisms whereby repeated long-term sub-concussion induces cerebral structural and neurobehavioural changes are currently unknown. Here, we utilised an established rat model to investigate the effects of repeated sub-concussion on size of lateral ventricles, cerebrovascular blood–brain barrier (BBB) integrity, neuroinflammation, oxidative stress, and biochemical distribution. Following repeated sub-concussion 3 days per week for 2 weeks, the rats showed significantly enlarged lateral ventricles compared with the rats receiving sham-only procedure. The sub-concussive rats also presented significant BBB dysfunction in the cerebral cortex and hippocampal formation, whilst neuromotor function assessed by beamwalk and rotarod tests were comparable to the sham rats. Immunofluorescent and spectroscopic microscopy analyses revealed no significant changes in neuroinflammation, oxidative stress, lipid distribution or protein aggregation, within the hippocampus and cortex. These data collectively indicate that repeated sub-concussion for 2 weeks induce significant ventriculomegaly and BBB disruption, preceding neuromotor deficits. © 2021, The Author(s). *Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Andrew Lavender” is provided in this record**

Can optimum solar radiation exposure or supplemented vitamin D intake reduce the severity of COVID-19 symptoms?

  • Authors: Abraham, Joji , Dowling, Kim , Florentine, Singarayer
  • Date: 2021
  • Type: Text , Journal article , Review
  • Relation: International Journal of Environmental Research and Public Health Vol. 18, no. 2 (2021), p. 1-21
  • Full Text:
  • Reviewed:
  • Description: The foremost mortality-causing symptom associated with COVID-19 is acute respiratory distress syndrome (ARDS). A significant correlation has been identified between the deficiency in vitamin D and the risk of developing ARDS. It has been suggested that if we can reduce or modify ARDS in COVID-19 patients, we may significantly reduce the severity of COVID-19 symptoms and associated mortality rates. The increased mortality of dark-skinned people, who have a reduced UV absorption capacity, may be consistent with diminished vitamin D status. The factors associated with COVID-19 mortality, such as old age, ethnicity, obesity, hypertension, cardiovascular diseases, and diabetes, are all found to be linked with vitamin D deficiency. Based on this review and as a precautionary measure, it is suggested that the adoption of appropriate and safe solar exposure and vitamin D enriched foods and supplements should be considered to reduce the possible severity of COVID-19 symptoms. Safe sun exposure is deemed beneficial globally, specifically in low and middle- income countries, as there is no cost involved. It is also noted that improved solar exposure and vitamin D levels can reduce the impact of other diseases as well, thus assisting in maintaining general human well-being. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Changes in tobacco use patterns during COVID-19 and their correlates among older adults in Bangladesh

  • Authors: Mistry, Sabuj , Ali, , Armm , Rahman, Md Ashfikur , Yadav, , Uday , Rahman, Muhammad Aziz
  • Date: 2021
  • Type: Text , Journal article
  • Relation: International Journal of Environmental Research and Public Health Vol. 18, no. 4 (2021), p. 1-11
  • Full Text:
  • Reviewed:
  • Description: The present study explored the changes in tobacco use patterns during the COVID-19 pandemic and their correlates among older adults in Bangladesh. This cross-sectional study was conducted among 1032 older adults aged ≥60 years in Bangladesh through telephone interviews in October 2020. Participants’ characteristics and COVID-19-related information were gathered using a pretested semi-structured questionnaire. Participants were asked if they noted any change in their tobacco use patterns (smoking or smokeless tobacco) during the COVID-19 pandemic compared to pre-pandemic (6 months prior to the survey). Nearly half of the participants (45.6%) were current tobacco users, of whom 15.9% reported increased tobacco use during the COVID-19 pandemic and all others had no change in their tobacco use patterns. Tobacco use was significantly increased among the participants from rural areas, who had reduced communications during COVID-19 compared to pre-pandemic (OR = 2.76, 95%CI:1.51–5.03). Participants who were aged ≥70 years (OR = 0.33, 95% CI: 0.14–0.77), widowed (OR = 0.36, 95% CI: 0.13–1.00), had pre-existing, non-communi-cable, and/or chronic conditions (OR = 0.44, 95% CI:0.25–0.78), and felt themselves at the highest risk of COVID-19 (OR = 0.31, 95% CI: 0.15–0.62), had significantly lower odds of increased tobacco use. Policy makers and practitioners need to focus on strengthening awareness and raising initia-tives to avoid tobacco use during such a crisis period. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. **Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Muhammad Aziz Rahman” is provided in this record**

Continuing the discussion about ecological futures for the lower Murray River (Australia) in the Anthropocene

  • Authors: Finlayson, C. Max , Gell, Peter , Conallin, John
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Marine and Freshwater Research Vol. 73, no. 10 (2021), p. 1241-1244
  • Full Text:
  • Reviewed:
  • Description: The lower Murray River (Australia) has been subject to considerable change from human activities, including the conversion of a variable flow system to one with regulated water levels and the conversion of the estuary to a freshwater system. These conditions will face further pressures owing to reduced flows and higher sea levels associated with climate change. Policy decisions to retain present target conditions could be reconsidered to improve habitat conditions for wetlands, native fish and waterbirds. Contrary to many views, this would be permissible under the Ramsar Convention and, by increasing the diversity of conditions, may assist managers to retain functional systems. This paper encourages a new conversation across the broader community to develop pathways to prepare for emerging pressures on the riverine ecosystems, and move into anthropogenic futures for the Lower Murray. © 2021 CSIRO. All rights reserved.

Data-driven decision-making in COVID-19 response : a survey

  • Authors: Yu, Shuo , Qing, Qing , Zhang, Chen , Shehzad, Ahsan , Oatley, Giles , Xia, Feng
  • Date: 2021
  • Type: Text , Journal article , Review
  • Relation: IEEE Transactions on Computational Social Systems Vol. 8, no. 4 (2021), p. 989-1002
  • Full Text:
  • Reviewed:
  • Description: COVID-19 has spread all over the world, having an enormous effect on our daily life and work. In response to the epidemic, a lot of important decisions need to be taken to save communities and economies worldwide. Data clearly play a vital role in effective decision-making. Data-driven decision-making uses data-related evidence and insights to guide the decision-making process and verify the plan of action before it is committed. To better handle the epidemic, governments and policy-making institutes have investigated abundant data originating from COVID-19. These data include those related to medicine, knowledge, media, and so on. Based on these data, many prevention and control policies are made. In this survey article, we summarize the progress of data-driven decision-making in the response to COVID-19, including COVID-19 prevention and control, psychological counseling, financial aid, work resumption, and school reopening. We also propose some current challenges and open issues in data-driven decision-making, including data collection and quality, complex data analysis, and fairness in decision-making. This survey article sheds light on current policy-making driven by data, which also provides a feasible direction for further scientific research. © 2014 IEEE.

Does climate play any role in covid-19 spreading? : an Australian perspective

  • Authors: Abraham, Joji , Turville, Christopher , Dowling, Kim , Florentine, Singarayer
  • Date: 2021
  • Type: Text , Journal article
  • Relation: International Journal of Environmental Research and Public Health Vol. 18, no. 17 (2021), p.
  • Full Text:
  • Reviewed:
  • Description: Compared to other countries, the COVID-19 pandemic did not severely affect Australia as measured by total deaths until mid-2021. Though a substantial number of daily confirmed cases (up to 698) were reported during the second wave, most of them were from the southern state of Victoria. This study examined the possible correlations between climate variables and the number of daily confirmed COVID-19 cases in Victoria, Australia, from 25 January to 31 October 2020. Appropriate regression models and cross-correlation diagnostics were used to examine the effect of temperature, rainfall, solar exposure, and ultraviolet index (UVI) with the number of daily confirmed cases. Significant positive associations were identified for solar exposure and maximum and average UVI for confirmed cases one and 19 days later. Negative associations for these variables were found for confirmed cases five days later. Minimum temperature had a significant negative correlation one day later and a positive effect 21 days later. No significant correlation was found for maximum temperature and rainfall. The most significant relationships were found for confirmed cases 19 days after changes in the meteorological variables. A 1% increase in solar exposure, maximum UVI, and average UVI was associated with a 0.31% (95% CI: 0.13 to 0.51), 0.71% (95% CI: 0.43 to 0.98), and 0.63% (95%CI: 0.20 to 1.61) increase 19 days later in the number of confirmed cases, respectively. The implications of these results can be used in the public health management of any possible future events in Australia. It also highlights the significance of considering the climatic variables and seasonality in all kinds of epidemics and pandemics. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Duration of intervals in the care seeking pathway for lung cancer in Bangladesh : a journey from symptoms triggering consultation to receipt of treatment

  • Authors: Ansar, Adnan , Lewis, Virginia , McDonald, Christine , Liu, , Chaojie , Rahman, Muhammad Aziz
  • Date: 2021
  • Type: Text , Journal article
  • Relation: PLoS ONE Vol. 16, no. 9 September (2021), p.
  • Full Text:
  • Reviewed:
  • Description: Timeliness in seeking care is critical for lung cancer patients survival and better prognosis. The care seeking trajectory of patients with lung cancer in Bangladesh has not been explored, despite the differences in health systems and structures compared to high income countries. This study investigated the symptoms triggering healthcare seeking, preferred healthcare providers (including informal healthcare providers such as pharmacy retailers, village doctors, and "traditional healers"), and the duration of intervals in the lung cancer care pathway of patients in Bangladesh. A cross-sectional study was conducted in three tertiary care hospitals in Bangladesh among diagnosed lung cancer patients through face-Toface interview and medical record review. Time intervals from onset of symptom and care seeking events were calculated and compared between those who sought initial care from different providers using Wilcoxon rank sum tests. Among 418 study participants, the majority (90%) of whom were males, with a mean age of 57 ±9.86 years, cough and chest pain were the most common (23%) combination of symptoms triggering healthcare seeking. About two-Thirds of the total respondents (60%) went to informal healthcare providers as their first point of contact. Living in rural areas, lower levels of education and lower income were associated with seeking care from such providers. The median duration between onset of symptom to confirmation of diagnosis was 121 days, between confirmation of diagnosis and initiation of treatment was 22 days, and between onset of symptom and initiation of treatment was 151 days. Pre-diagnosis durations were longer for those who had sought initial care from an informal provider (p<0.05). Time to first contact with a health provider was shorter in this study compared to other developed and developing countries but utilizing informal healthcare providers caused delays in diagnosis and initiation of treatment. Encouraging people to seek care from a formal healthcare provider may reduce the overall duration of the care seeking pathway. © 2021 Public Library of Science. All rights reserved.

Effectiveness of mouth rinsing versus ingesting pickle juice for alleviating electrically induced cramp in physically active adults

  • Authors: Georgieva, Julia , Brade, Carly , Ducker, Kagan , Davey, Paul , Jacques, Angela , Ohno, Masato , Lavender, Andrew
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Applied Sciences (Switzerland) Vol. 11, no. 24 (2021), p.
  • Full Text:
  • Reviewed:
  • Description: (1) Background: Stimulating oropharyngeal transient receptor potential (TRP) channels in-hibits muscle cramping by triggering a supraspinal reflex to reduce α-motor neuron hyperexcitability. This study investigated whether the longer stimulation of the TRP channels via mouth rinsing with PJ is more effective than drinking PJ at inhibiting an electrically induced muscle cramp (EIMC). Both conditions were compared to the control (water). (2) Methods: The tibial nerves in 11 cramp-prone adults were percutaneously stimulated to elicit an EIMC of the flexor hallucis brevis in three trials that took place one week apart from each other. At cramp onset, the participants received mouth rinsing and expelling PJ (25 mL), ingesting PJ (1 mL·kg−1 body-mass (BM)), or ingesting water (1 mL·kg−1 BM). Cramp onset and offset were induced by electromyography, and the severity of discomfort was recorded using a visual analogue scale (VAS). (3) Results: The median time to cramp cessation as a percentage of water was 82.8 ± 14.63% and 68.6 ± 47.78% for PJ ingestion and PJ mouth rinsing, respectively. These results had large variability, and no statistically significant differences were observed. There were also no differences in perceived cramp discomfort between conditions, despite the hazard ratios for the time taken to reach VAS = 0, which was higher than water (control) for PJ ingestion (22%) and mouth rinsing (35%) (p = 0.66 and 0.51, respectively). (4) Conclusions: The data suggest no difference in cramp duration and perceived discomfort between PJ and water. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. **Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Andrew Lavender” is provided in this record**

Establishment of sex difference in circulating uric acid is associated with higher testosterone and lower sex hormone-binding globulin in adolescent boys

  • Authors: Wang, Yutang , Charchar, Fadi
  • Date: 2021
  • Type: Text , Journal article
  • Relation: Scientific Reports Vol. 11, no. 1 (2021), p.
  • Relation: https://purl.org/au-research/grants/nhmrc/1062671
  • Full Text:
  • Reviewed:
  • Description: Men have higher circulating levels of uric acid than women. This sex difference is suspected to be a result of suppressive effects of estradiol on uric acid. If so, estradiol would be inversely associated with circulating uric acid. This study aimed to test this hypothesis. This cross-sectional study included 9472 participants (weighted sample size of 184,342,210) aged 12–80 years from the 2013 to 2016 US National Health and Nutrition Examination Survey. Associations of sex hormones with uric acid were analyzed using weighted least squares regression, adjusting for demographic characteristics, lifestyle risk factors, and comorbidities. Neither free nor bioavailable estradiol was inversely associated with circulating uric acid in adolescent boys or girls, or adult men or women, or perimenopausal women after full adjustment. The sex difference in uric acid was established during adolescence as a result of a dramatic increase in uric acid in adolescent boys. During adolescence, the increase in estradiol in girls over time was accompanied by a relatively unchanged level of uric acid. All three fractions of estradiol (free, bioavailable, and total) were positively associated with uric acid in adolescent boys and girls after full adjustment. In adolescent boys, all three fractions of testosterone were positively associated with serum uric acid, and sex hormone-binding globulin was inversely associated with uric acid after full adjustment. These results suggest that estradiol is not inversely associated with circulating uric acid in adolescents and the establishment of sex difference in circulating uric acid during adolescence is associated with higher testosterone and lower sex hormone-binding globulin in adolescent boys. © 2021, The Author(s).

Exclusive breastfeeding continuation and associated factors among employed women in North Ethiopia : a cross-sectional study

  • Authors: Gebrekidan, Kahsu , Hall, Helen , Plummer, Virginia , Fooladi, Ensieh
  • Date: 2021
  • Type: Text , Journal article
  • Relation: PLoS ONE Vol. 16, no. 7 (2021), p.
  • Full Text:
  • Reviewed:
  • Description: Background Exclusive Breastfeeding (EBF) can prevent up to 13% of under-five mortality in developing countries. In Sub-Saharan Africa the rate of EBF at six months remains very low at 36%. Different types of factors such as maternal, family and work-related factors are responsible for the low rate of EBF among employed women. This study aimed to assess the prevalence of EBF continuation and associated factors among employed women in North Ethiopia. Materials and methods A community-based, cross-sectional study was conducted in two towns of Tigray region, North Ethiopia. Employed women who had children between six months and two years were surveyed using multistage, convenience sampling. Women filled in a paper based validated questionnaire adopted from the Breastfeeding and Employment Study toolkit (BESt). The questions were grouped into four parts of sociodemographic characteristics, maternal characteristics, family support and work-related factors. Factors associated with EBF continuation as a binary outcome (yes/no) were determined using multivariable logistic regression. Results Four-hundred and forty-nine women participated in this study with a mean (SD) age 30.4 (4.2) years. Two hundred and fifty-four (56.4%) participants exclusively breastfed their children for six months or more. The main reason for discontinuation of EBF was the requirement of women to return to paid employment (31.5%). Four-hundred and forty (98.2%) participants believed that breastfeeding has benefits either to the infant or to the mother. Three hundred and seventy-one (82.8%) of the participants received support from their family at home to assist with EBF, most commonly from their husbands and mothers. Having family support (adjusted odds ratio [AOR] = 2.1, 95%, CI 1.2–3.6; P = 0.005), having frequent breaks at work (AOR = 2.6, 95% CI, 1.4–4.8; P = 0.002) and the possibility of buying or borrowing required equipment for expressing breast milk (AOR = 1.7, 95% CI, 1.0–3.0; P = 0.033) were statistically associated with an increased chance of EBF. Conclusion Although returning to work was reported by the study participants as the main reason for discontinuation of EBF, families and managers’ support play significant roles in EBF continuation, which in the absence of six-month’s maternity leave for employed women in Ethiopia would be of benefit to both mothers and children. © 2021 Gebrekidan et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Factors associated with chronic kidney disease in patients with type 2 diabetes in Bangladesh

  • Authors: Islam, Sheikh , Salehin, Masudus , Zaman, Sojib , Tansi, Tania , Gupta, Rajat
  • Date: 2021
  • Type: Text , Journal article
  • Relation: International Journal of Environmental Research and Public Health Vol. 18, no. 23 (2021), p.
  • Full Text:
  • Reviewed:
  • Description: Diabetes and chronic kidney disease (CKD) are a major public health burden in low- and middle-income countries. This study aimed to explore factors associated with CKD in patients with type 2 diabetes (T2D) in Bangladesh. A cross-sectional study was conducted among 315 adults with T2D presenting at the outpatient department of Bangladesh Institute of Health Sciences (BIHS) hospital between July 2013 to December 2013. CKD was diagnosed based on the estimated glomerular filtration rate using the ‘Modification of Diet in Renal Disease’ equations and the presence of albu-minuria estimated by the albumin-to-creatinine ratio. Multivariate logistic regression analysis was used to determine the factors associated with CKD. The overall prevalence of CKD among patients with T2D was 21.3%. In the unadjusted model, factors associated with CKD included age 40–49 years (OR: 5.7, 95% CI: 1.3–25.4), age 50–59 years (7.0, 1.6–39), age ≥60 years (7.6, 1.7–34), being female (2.2, 1.2–3.8), being hypertensive (1.9, 1.1–3.5), and household income between 10,001 and 20,000 Bangladeshi taka, BDT (2.9, 1.0–8.2) compared with income ≤10,000 BDT. However, after ad-justment of other covariates, only the duration of hypertension and household income (10,001– 20,000 BDT) remained statistically significant. There is a need to implement policies and programs for early detection and management of hypertension and CKD in T2D patients in Bangladesh. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. **Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Masudus Salehin” is provided in this record**