A global optimisation approach to classification in medical diagnosis and prognosis
- Authors: Bagirov, Adil , Rubinov, Alex , Yearwood, John , Stranieri, Andrew
- Date: 2001
- Type: Text , Conference paper
- Relation: Paper presented at 34th Hawaii International Conference on System Sciences, HICSS-34, Maui, Hawaii, USA : 3rd-6th January 2001
- Full Text:
- Description: In this paper global optimisation-based techniques are studied in order to increase the accuracy of medical diagnosis and prognosis with FNA image data from the Wisconsin Diagnostic and Prognostic Breast Cancer databases. First we discuss the problem of determining the most informative features for the classification of cancerous cases in the databases under consideration. Then we apply a technique based on convex and global optimisation to breast cancer diagnosis. It allows the classification of benign cases and malignant ones and the subsequent diagnosis of patients with very high accuracy. The third application of this technique is a method that calculates centres of clusters to predict when breast cancer is likely to recur in patients for which cancer has been removed. The technique achieves higher accuracy with these databases than reported elsewhere in the literature.
- Description: 2003003950
Using global optimization to improve classification for medical diagnosis and prognosis
- Authors: Bagirov, Adil , Rubinov, Alex , Yearwood, John
- Date: 2001
- Type: Text , Journal article
- Relation: Topics in health information management Vol. 22, no. 1 (2001), p. 65-74
- Full Text: false
- Description: Global optimization-based techniques are studied in order to increase the accuracy of medical diagnosis and prognosis with data from various databases. First, we discuss feature selection, the problem of determining the most informative features for classification in the databases under consideration. Then, we apply a technique based on convex and global optimization for classification in these databases. The third application of this technique is a method that calculates centers of clusters to predict when breast cancer is likely to recur in patients for which cancer has been removed. The technique achieves high accuracy with these databases. Better classifiers will lead to improved assistance in making medical diagnostic and prognostic decisions.
- Description: 2003003662
A global optimization approach to classification
- Authors: Bagirov, Adil , Rubinov, Alex , Yearwood, John
- Date: 2002
- Type: Text , Journal article
- Relation: Optimization and Engineering Vol. 9, no. 7 (2002), p. 129-155
- Full Text: false
- Reviewed:
- Description: In this paper is presented an hybrid algorithm for finding the absolute extreme point of a multimodal scalar function of many variables. The algorithm is suitable when the objective function is expensive to compute, the computation can be affected by noise and/or partial derivatives cannot be calculated. The method used is a genetic modification of a previous algorithm based on the Prices method. All information about behavior of objective function collected on previous iterates are used to chose new evaluation points. The genetic part of the algorithm is very effective to escape from local attractors of the algorithm and assures convergence in probability to the global optimum. The proposed algorithm has been tested on a large set of multimodal test problems outperforming both the modified Prices algorithm and classical genetic approach.
- Description: C1
- Description: 2003000061
An algorithm for clustering based on non-smooth optimization techniques
- Authors: Bagirov, Adil , Rubinov, Alex , Sukhorukova, Nadezda , Yearwood, John
- Date: 2003
- Type: Text , Journal article
- Relation: International Transactions in Operational Research Vol. 10, no. 6 (2003), p. 611-617
- Full Text: false
- Reviewed:
- Description: The problem of cluster analysis is formulated as a problem of non-smooth, non-convex optimization, and an algorithm for solving the cluster analysis problem based on non-smooth optimization techniques is developed. We discuss applications of this algorithm in large databases. Results of numerical experiments are presented to demonstrate the effectiveness of this algorithm.
- Description: C1
- Description: 2003000422
Analysis of the Australian credit database
- Authors: Rubinov, Alex , Sukhorukova, Nadezda , Yearwood, John
- Date: 2003
- Type: Text , Conference paper
- Relation: Paper presented at the Symposium on Industrial Optimisation and the 9th Australian Optimisation Day, Perth : 30th September, 2002
- Full Text: false
- Reviewed:
- Description: E1
- Description: 2003000353
Dynamical systems based on a fuzzy derivative and its applications to data classification
- Authors: Mammadov, Musa , Rubinov, Alex , Yearwood, John
- Date: 2003
- Type: Text , Conference paper
- Relation: Paper presented at the Industrial Optimisation 2003 Conference, Perth : 30th September, 2002
- Full Text: false
- Reviewed:
- Description: E1
- Description: 2003000339
Unsupervised and supervised data classification via nonsmooth and global optimisation
- Authors: Bagirov, Adil , Rubinov, Alex , Sukhorukova, Nadezda , Yearwood, John
- Date: 2003
- Type: Text , Journal article
- Relation: Top Vol. 11, no. 1 (2003), p. 1-92
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- Reviewed:
- Description: We examine various methods for data clustering and data classification that are based on the minimization of the so-called cluster function and its modications. These functions are nonsmooth and nonconvex. We use Discrete Gradient methods for their local minimization. We consider also a combination of this method with the cutting angle method for global minimization. We present and discuss results of numerical experiments.
- Description: C1
- Description: 2003000421
Dynamical systems described by relational elasticities with applications to global optimization
- Authors: Mammadov, Musa , Rubinov, Alex , Yearwood, John
- Date: 2005
- Type: Text , Book chapter
- Relation: Continuous Optimization: Current Trends and Modern Applications Chapter p. 365-385
- Full Text: false
- Reviewed:
- Description: B1
The study of drug-reaction relationships using global optimization techniques
- Authors: Mammadov, Musa , Rubinov, Alex , Yearwood, John
- Date: 2007
- Type: Text , Journal article
- Relation: Optimization Methods and Software Vol. 22, no. 1 (2007), p. 99-126
- Full Text: false
- Reviewed:
- Description: In this paper we develop an optimization approach for the study of adverse drug reaction (ADR) problems. This approach is based on drug-reaction relationships represented in the form of a vector of weights, which can be defined as a solution to some global optimization problem. Although it can be used for solving many ADR problems, we concentrate on two of them here: the accurate identification of drugs that are responsible for reactions that have occurred, and drug-drug interactions. Based on drug-reaction relationships, we formulate these problems as an optimization problem. The approach is applied to cardiovascularn-type reactions from the Australian Adverse Drug Reaction Advisory Committee (ADRAC) database. Software based on this approach has been developed and could have beneficial use in prescribing.
- Description: C1
- Description: 2003002217