- Wang, Anni, Guo, Yufang, Cross, Wendy, Lam, Louisa, Plummer, Virginia, Zhang, Wen, Zhang, Jingping
- Authors: Wang, Anni , Guo, Yufang , Cross, Wendy , Lam, Louisa , Plummer, Virginia , Zhang, Wen , Zhang, Jingping
- Date: 2024
- Type: Text , Journal article
- Relation: Psychol Trauma Vol. 16, no. 2 (2024), p. 167-175
- Full Text: false
- Reviewed:
- Description: Objective: Parents who lose an only child in China are stressed and traumatized due to social identity threat (SIT). This qualitative study aimed to interpret their experience to inform culturally and socially sensitive intervention strategies. Methods: Using a phenomenological approach, 17 bereaved parents who lost an only child were interviewed. The transcripts were analyzed using Colaizzi's method. Results: Three themes were identified, namely, "assuming a new social identity," "triggering social identity threat," and "resisting social identity threat and maintaining resilience." The study showed that SIT initially began with identity reconstruction, where self-identity and social identity occurred 1 after another. Once labeled with such social identity, the bereaved parents suffered social identity threat triggered by inner inferiority and external stigmatization. The bereaved parents undertook a variety of coping strategies to resist the threat and to maintain resilience of these strategies, 4 patterns depicting resilience and threat were interpreted. Conclusion: The findings offer an understanding of the multifaceted bereavement dilemma and lay a foundation for developing intervention strategies. Promoting or maintaining resilience and alleviating SIT are 2 important ways that help parents move on. To help them with identity reconstruction, the development of culturally sensitive resilience-based programs and the linking of social resources to solve practical problems are recommended. Community health professionals should encourage parents to maintain good health management to prevent their predicament from worsening. Raising economic assistance, building an elderly care support system, and promoting social acceptance are strategies that could be considered by policymakers. Clinical Impact StatementThe bereaved parents who have lost an only child in China is facing a multifaceted dilemma, which involves psychological, economic and cultural issues. This study applies the construct of social identity threat to interpretive lived experience of parents in China who have lost their only child. The study contributes to better understanding of their multifaceted bereavement dilemma, and lay the foundation for developing psycho-behavioural intervention strategies, which potentially also benefit other marginalized or traumatized bereaved groups. Results in this study offered several recommendations for psychological counselors, community workers, community health professionals, and government policymakers.
Fuzzy multiplier, sum and intersection rules in non-Lipschitzian settings : decoupling approach revisited
- Fabian, Marian, Kruger, Alexander, Mehlitz, Patrick
- Authors: Fabian, Marian , Kruger, Alexander , Mehlitz, Patrick
- Date: 2024
- Type: Text , Journal article
- Relation: Journal of Mathematical Analysis and Applications Vol. 532, no. 2 (2024), p.
- Relation: https://purl.org/au-research/grants/arc/DP160100854
- Full Text:
- Reviewed:
- Description: We revisit the decoupling approach widely used (often intuitively) in nonlinear analysis and optimization and initially formalized about a quarter of a century ago by Borwein & Zhu, Borwein & Ioffe and Lassonde. It allows one to streamline proofs of necessary optimality conditions and calculus relations, unify and simplify the respective statements, clarify and in many cases weaken the assumptions. In this paper we study weaker concepts of quasiuniform infimum, quasiuniform lower semicontinuity and quasiuniform minimum, putting them into the context of the general theory developed by the aforementioned authors. Along the way, we unify the terminology and notation and fill in some gaps in the general theory. We establish rather general primal and dual necessary conditions characterizing quasiuniform
- Authors: Fabian, Marian , Kruger, Alexander , Mehlitz, Patrick
- Date: 2024
- Type: Text , Journal article
- Relation: Journal of Mathematical Analysis and Applications Vol. 532, no. 2 (2024), p.
- Relation: https://purl.org/au-research/grants/arc/DP160100854
- Full Text:
- Reviewed:
- Description: We revisit the decoupling approach widely used (often intuitively) in nonlinear analysis and optimization and initially formalized about a quarter of a century ago by Borwein & Zhu, Borwein & Ioffe and Lassonde. It allows one to streamline proofs of necessary optimality conditions and calculus relations, unify and simplify the respective statements, clarify and in many cases weaken the assumptions. In this paper we study weaker concepts of quasiuniform infimum, quasiuniform lower semicontinuity and quasiuniform minimum, putting them into the context of the general theory developed by the aforementioned authors. Along the way, we unify the terminology and notation and fill in some gaps in the general theory. We establish rather general primal and dual necessary conditions characterizing quasiuniform
Lifestyle management of hypertension : International Society of Hypertension position paper endorsed by the World Hypertension League and European Society of Hypertension
- Charchar, Fadi, Prestes, Priscilla, Mills, Charlotte, Ching, Siew, Neupane, Dinesh, Marques, Francine, Sharman, James, Vogt, Liffert, Burrell, Louise, Korostovtseva, Lyudmila, Zec, Manja, Patil, Mansi, Schultz, Martin, Wallen, Matthew, Renna, Nicolás, Islam, Sheikh, Hiremath, Swapnil, Gyeltshen, Tshewang, Chia, Yook-Chin, Gupta, Abhinav, Schutte, Aletta, Klein, Britt, Borghi, Claudio, Browning, Colette, Czesnikiewicz-Guzik, Marta, Lee, Hae-Young, Itoh, Hiroshi, Miura, Katsuyuki, Akinnibosun, Olutope, Shane Thomas
- Authors: Charchar, Fadi , Prestes, Priscilla , Mills, Charlotte , Ching, Siew , Neupane, Dinesh , Marques, Francine , Sharman, James , Vogt, Liffert , Burrell, Louise , Korostovtseva, Lyudmila , Zec, Manja , Patil, Mansi , Schultz, Martin , Wallen, Matthew , Renna, Nicolás , Islam, Sheikh , Hiremath, Swapnil , Gyeltshen, Tshewang , Chia, Yook-Chin , Gupta, Abhinav , Schutte, Aletta , Klein, Britt , Borghi, Claudio , Browning, Colette , Czesnikiewicz-Guzik, Marta , Lee, Hae-Young , Itoh, Hiroshi , Miura, Katsuyuki , Akinnibosun, Olutope , Shane Thomas
- Date: 2024
- Type: Text , Journal article
- Relation: Journal of hypertension Vol. 42, no. 1 (2024), p. 23-49
- Full Text:
- Reviewed:
- Description: Hypertension, defined as persistently elevated systolic blood pressure (SBP) >140 mmHg and/or diastolic blood pressure (DBP) at least 90 mmHg (International Society of Hypertension guidelines), affects over 1.5 billion people worldwide. Hypertension is associated with increased risk of cardiovascular disease (CVD) events (e.g. coronary heart disease, heart failure and stroke) and death. An international panel of experts convened by the International Society of Hypertension College of Experts compiled lifestyle management recommendations as first-line strategy to prevent and control hypertension in adulthood. We also recommend that lifestyle changes be continued even when blood pressure-lowering medications are prescribed. Specific recommendations based on literature evidence are summarized with advice to start these measures early in life, including maintaining a healthy body weight, increased levels of different types of physical activity, healthy eating and drinking, avoidance and cessation of smoking and alcohol use, management of stress and sleep levels. We also discuss the relevance of specific approaches including consumption of sodium, potassium, sugar, fibre, coffee, tea, intermittent fasting as well as integrated strategies to implement these recommendations using, for example, behaviour change-related technologies and digital tools. **Please note that there are multiple authors for this article therefore only the name of the first 30 including Federation University Australia affiliates “Fadi Charchar, Priscilla Prestes, Britt Klein, Colette Browning, Olutope Akinnibosun and Shane Thomas” are provided in this record**
- Description: Hypertension, defined as persistently elevated systolic blood pressure (SBP) >140 mmHg and/or diastolic blood pressure (DBP) at least 90 mmHg (International Society of Hypertension guidelines), affects over 1.5 billion people worldwide. Hypertension is associated with increased risk of cardiovascular disease (CVD) events (e.g. coronary heart disease, heart failure and stroke) and death. An international panel of experts convened by the International Society of Hypertension College of Experts compiled lifestyle management recommendations as first-line strategy to prevent and control hypertension in adulthood. We also recommend that lifestyle changes be continued even when blood pressure-lowering medications are prescribed. Specific recommendations based on literature evidence are summarized with advice to start these measures early in life, including maintaining a healthy body weight, increased levels of different types of physical activity, healthy eating and drinking, avoidance and cessation of smoking and alcohol use, management of stress and sleep levels. We also discuss the relevance of specific approaches including consumption of sodium, potassium, sugar, fibre, coffee, tea, intermittent fasting as well as integrated strategies to implement these recommendations using, for example, behaviour change-related technologies and digital tools. **Please note that there are multiple authors for this article therefore only the name of the first 30 including Federation University Australia affiliates “Fadi Charchar, Priscilla Prestes, Britt Klein, Colette Browning, Olutope Akinnibossun and Shane Thomas” are provided in this record**
- Authors: Charchar, Fadi , Prestes, Priscilla , Mills, Charlotte , Ching, Siew , Neupane, Dinesh , Marques, Francine , Sharman, James , Vogt, Liffert , Burrell, Louise , Korostovtseva, Lyudmila , Zec, Manja , Patil, Mansi , Schultz, Martin , Wallen, Matthew , Renna, Nicolás , Islam, Sheikh , Hiremath, Swapnil , Gyeltshen, Tshewang , Chia, Yook-Chin , Gupta, Abhinav , Schutte, Aletta , Klein, Britt , Borghi, Claudio , Browning, Colette , Czesnikiewicz-Guzik, Marta , Lee, Hae-Young , Itoh, Hiroshi , Miura, Katsuyuki , Akinnibosun, Olutope , Shane Thomas
- Date: 2024
- Type: Text , Journal article
- Relation: Journal of hypertension Vol. 42, no. 1 (2024), p. 23-49
- Full Text:
- Reviewed:
- Description: Hypertension, defined as persistently elevated systolic blood pressure (SBP) >140 mmHg and/or diastolic blood pressure (DBP) at least 90 mmHg (International Society of Hypertension guidelines), affects over 1.5 billion people worldwide. Hypertension is associated with increased risk of cardiovascular disease (CVD) events (e.g. coronary heart disease, heart failure and stroke) and death. An international panel of experts convened by the International Society of Hypertension College of Experts compiled lifestyle management recommendations as first-line strategy to prevent and control hypertension in adulthood. We also recommend that lifestyle changes be continued even when blood pressure-lowering medications are prescribed. Specific recommendations based on literature evidence are summarized with advice to start these measures early in life, including maintaining a healthy body weight, increased levels of different types of physical activity, healthy eating and drinking, avoidance and cessation of smoking and alcohol use, management of stress and sleep levels. We also discuss the relevance of specific approaches including consumption of sodium, potassium, sugar, fibre, coffee, tea, intermittent fasting as well as integrated strategies to implement these recommendations using, for example, behaviour change-related technologies and digital tools. **Please note that there are multiple authors for this article therefore only the name of the first 30 including Federation University Australia affiliates “Fadi Charchar, Priscilla Prestes, Britt Klein, Colette Browning, Olutope Akinnibosun and Shane Thomas” are provided in this record**
- Description: Hypertension, defined as persistently elevated systolic blood pressure (SBP) >140 mmHg and/or diastolic blood pressure (DBP) at least 90 mmHg (International Society of Hypertension guidelines), affects over 1.5 billion people worldwide. Hypertension is associated with increased risk of cardiovascular disease (CVD) events (e.g. coronary heart disease, heart failure and stroke) and death. An international panel of experts convened by the International Society of Hypertension College of Experts compiled lifestyle management recommendations as first-line strategy to prevent and control hypertension in adulthood. We also recommend that lifestyle changes be continued even when blood pressure-lowering medications are prescribed. Specific recommendations based on literature evidence are summarized with advice to start these measures early in life, including maintaining a healthy body weight, increased levels of different types of physical activity, healthy eating and drinking, avoidance and cessation of smoking and alcohol use, management of stress and sleep levels. We also discuss the relevance of specific approaches including consumption of sodium, potassium, sugar, fibre, coffee, tea, intermittent fasting as well as integrated strategies to implement these recommendations using, for example, behaviour change-related technologies and digital tools. **Please note that there are multiple authors for this article therefore only the name of the first 30 including Federation University Australia affiliates “Fadi Charchar, Priscilla Prestes, Britt Klein, Colette Browning, Olutope Akinnibossun and Shane Thomas” are provided in this record**
The linkedness of cubical polytopes : beyond the cube
- Bui, Hoa, Pineda-Villavicencio, Guillermo, Ugon, Julien
- Authors: Bui, Hoa , Pineda-Villavicencio, Guillermo , Ugon, Julien
- Date: 2024
- Type: Text , Journal article
- Relation: Discrete Mathematics Vol. 347, no. 3 (2024), p.
- Relation: https://purl.org/au-research/grants/arc/DP180100602
- Full Text:
- Reviewed:
- Description: A cubical polytope is a polytope with all its facets being combinatorially equivalent to cubes. The paper is concerned with the linkedness of the graphs of cubical polytopes. A graph with at least 2k vertices is k-linked if, for every set of k disjoint pairs of vertices, there are k vertex-disjoint paths joining the vertices in the pairs. We say that a polytope is k-linked if its graph is k-linked. In a previous paper [3] we proved that every cubical d-polytope is ⌊d/2⌋-linked. Here we strengthen this result by establishing the ⌊(d+1)/2⌋-linkedness of cubical d-polytopes, for every d≠3. A graph G is strongly k-linked if it has at least 2k+1 vertices and, for every vertex v of G, the subgraph G−v is k-linked. We say that a polytope is (strongly) k-linked if its graph is (strongly) k-linked. In this paper, we also prove that every cubical d-polytope is strongly ⌊d/2⌋-linked, for every d≠3. These results are best possible for this class of polytopes.
- Description: A cubical polytope is a polytope with all its facets being combinatorially equivalent to cubes. The paper is concerned with the linkedness of the graphs of cubical polytopes. A graph with at least 2k vertices is k-linked if, for every set of k disjoint pairs of vertices, there are k vertex-disjoint paths joining the vertices in the pairs. We say that a polytope is k-linked if its graph is k-linked. In a previous paper [3] we proved that every cubical d-polytope is
- Authors: Bui, Hoa , Pineda-Villavicencio, Guillermo , Ugon, Julien
- Date: 2024
- Type: Text , Journal article
- Relation: Discrete Mathematics Vol. 347, no. 3 (2024), p.
- Relation: https://purl.org/au-research/grants/arc/DP180100602
- Full Text:
- Reviewed:
- Description: A cubical polytope is a polytope with all its facets being combinatorially equivalent to cubes. The paper is concerned with the linkedness of the graphs of cubical polytopes. A graph with at least 2k vertices is k-linked if, for every set of k disjoint pairs of vertices, there are k vertex-disjoint paths joining the vertices in the pairs. We say that a polytope is k-linked if its graph is k-linked. In a previous paper [3] we proved that every cubical d-polytope is ⌊d/2⌋-linked. Here we strengthen this result by establishing the ⌊(d+1)/2⌋-linkedness of cubical d-polytopes, for every d≠3. A graph G is strongly k-linked if it has at least 2k+1 vertices and, for every vertex v of G, the subgraph G−v is k-linked. We say that a polytope is (strongly) k-linked if its graph is (strongly) k-linked. In this paper, we also prove that every cubical d-polytope is strongly ⌊d/2⌋-linked, for every d≠3. These results are best possible for this class of polytopes.
- Description: A cubical polytope is a polytope with all its facets being combinatorially equivalent to cubes. The paper is concerned with the linkedness of the graphs of cubical polytopes. A graph with at least 2k vertices is k-linked if, for every set of k disjoint pairs of vertices, there are k vertex-disjoint paths joining the vertices in the pairs. We say that a polytope is k-linked if its graph is k-linked. In a previous paper [3] we proved that every cubical d-polytope is
A blockchain-based deep-learning-driven architecture for quality routing in wireless sensor networks
- Khan, Zahoor, Amjad, Sana, Ahmed, Farwa, Almasoud, Abdullah, Imran, Muhammad, Javaid, Nadeem
- Authors: Khan, Zahoor , Amjad, Sana , Ahmed, Farwa , Almasoud, Abdullah , Imran, Muhammad , Javaid, Nadeem
- Date: 2023
- Type: Text , Journal article
- Relation: IEEE Access Vol. 11, no. (2023), p. 31036-31051
- Full Text:
- Reviewed:
- Description: Over the past few years, great importance has been given to wireless sensor networks (WSNs) as they play a significant role in facilitating the world with daily life services like healthcare, military, social products, etc. However, heterogeneous nature of WSNs makes them prone to various attacks, which results in low throughput, and high network delay and high energy consumption. In the WSNs, routing is performed using different routing protocols like low-energy adaptive clustering hierarchy (LEACH), heterogeneous gateway-based energy-aware multi-hop routing (HMGEAR), etc. In such protocols, some nodes in the network may perform malicious activities. Therefore, four deep learning (DL) techniques and a real-time message content validation (RMCV) scheme based on blockchain are used in the proposed network for the detection of malicious nodes (MNs). Moreover, to analyse the routing data in the WSN, DL models are trained on a state-of-the-art dataset generated from LEACH, known as WSN-DS 2016. The WSN contains three types of nodes: sensor nodes, cluster heads (CHs) and the base station (BS). The CHs after aggregating the data received from the sensor nodes, send it towards the BS. Furthermore, to overcome the single point of failure issue, a decentralized blockchain is deployed on CHs and BS. Additionally, MNs are removed from the network using RMCV and DL techniques. Moreover, legitimate nodes (LNs) are registered in the blockchain network using proof-of-authority consensus protocol. The protocol outperforms proof-of-work in terms of computational cost. Later, routing is performed between the LNs using different routing protocols and the results are compared with original LEACH and HMGEAR protocols. The results show that the accuracy of GRU is 97%, LSTM is 96%, CNN is 92% and ANN is 90%. Throughput, delay and the death of the first node are computed for LEACH, LEACH with DL, LEACH with RMCV, HMGEAR, HMGEAR with DL and HMGEAR with RMCV. Moreover, Oyente is used to perform the formal security analysis of the designed smart contract. The analysis shows that blockchain network is resilient against vulnerabilities. © 2013 IEEE.
A blockchain-based deep-learning-driven architecture for quality routing in wireless sensor networks
- Authors: Khan, Zahoor , Amjad, Sana , Ahmed, Farwa , Almasoud, Abdullah , Imran, Muhammad , Javaid, Nadeem
- Date: 2023
- Type: Text , Journal article
- Relation: IEEE Access Vol. 11, no. (2023), p. 31036-31051
- Full Text:
- Reviewed:
- Description: Over the past few years, great importance has been given to wireless sensor networks (WSNs) as they play a significant role in facilitating the world with daily life services like healthcare, military, social products, etc. However, heterogeneous nature of WSNs makes them prone to various attacks, which results in low throughput, and high network delay and high energy consumption. In the WSNs, routing is performed using different routing protocols like low-energy adaptive clustering hierarchy (LEACH), heterogeneous gateway-based energy-aware multi-hop routing (HMGEAR), etc. In such protocols, some nodes in the network may perform malicious activities. Therefore, four deep learning (DL) techniques and a real-time message content validation (RMCV) scheme based on blockchain are used in the proposed network for the detection of malicious nodes (MNs). Moreover, to analyse the routing data in the WSN, DL models are trained on a state-of-the-art dataset generated from LEACH, known as WSN-DS 2016. The WSN contains three types of nodes: sensor nodes, cluster heads (CHs) and the base station (BS). The CHs after aggregating the data received from the sensor nodes, send it towards the BS. Furthermore, to overcome the single point of failure issue, a decentralized blockchain is deployed on CHs and BS. Additionally, MNs are removed from the network using RMCV and DL techniques. Moreover, legitimate nodes (LNs) are registered in the blockchain network using proof-of-authority consensus protocol. The protocol outperforms proof-of-work in terms of computational cost. Later, routing is performed between the LNs using different routing protocols and the results are compared with original LEACH and HMGEAR protocols. The results show that the accuracy of GRU is 97%, LSTM is 96%, CNN is 92% and ANN is 90%. Throughput, delay and the death of the first node are computed for LEACH, LEACH with DL, LEACH with RMCV, HMGEAR, HMGEAR with DL and HMGEAR with RMCV. Moreover, Oyente is used to perform the formal security analysis of the designed smart contract. The analysis shows that blockchain network is resilient against vulnerabilities. © 2013 IEEE.
A community-wide approach to reducing risky drinking cultures in young people in rural Australia
- Murphy, Angela, Ollerenshaw, Alison
- Authors: Murphy, Angela , Ollerenshaw, Alison
- Date: 2023
- Type: Text , Journal article
- Relation: Australian Journal of Rural Health Vol. 31, no. 2 (2023), p. 204-217
- Full Text:
- Reviewed:
- Description: Objective: This study evaluated the impact of a multi-faceted, harm minimisation program addressing youth alcohol change and risky drinking behaviours in rural Australia. The role and influence of a multi-tiered community approach to changing alcohol cultures is examined. Setting: An alcohol culture change project for young people (12–18 years) was implemented in rural Victoria. It was informed by the Alcohol Cultures Framework, comprising community-wide events and youth-focused activities, co-designed with young people. The approach aimed at maximising engagement and reducing alcohol-related harm by targeting the shared activities and drinking practices of young people, parents and the community. Participants: Participants (n = 446) provided feedback specific to three key program activities for promoting alcohol change. Design: Mixed methods: Feedback sheets were collected, and interviews and focus groups were conducted with program participants. Results: Participants indicated that the program had informed their understanding of the way people in their region drink, and the social norms and practices around alcohol that encourage risky drinking. It influenced their short- and medium-term reactions, learnings and activities relating to alcohol consumption. The impact of the program was greatest in adults than young people although reflective learning and some behaviour change were evident across all age groups and community clusters. Conclusion: Community-wide health promotion events offer participants a deeper understanding of the ways in which dominant alcohol cultures inform the practices and activities of young people within a broader community context. Ensuring health promotion programs within a whole-of-community approach are established longer term, is recommended. © 2022 The Authors. Australian Journal of Rural Health published by John Wiley & Sons Australia, Ltd on behalf of National Rural Health Alliance Ltd.
- Authors: Murphy, Angela , Ollerenshaw, Alison
- Date: 2023
- Type: Text , Journal article
- Relation: Australian Journal of Rural Health Vol. 31, no. 2 (2023), p. 204-217
- Full Text:
- Reviewed:
- Description: Objective: This study evaluated the impact of a multi-faceted, harm minimisation program addressing youth alcohol change and risky drinking behaviours in rural Australia. The role and influence of a multi-tiered community approach to changing alcohol cultures is examined. Setting: An alcohol culture change project for young people (12–18 years) was implemented in rural Victoria. It was informed by the Alcohol Cultures Framework, comprising community-wide events and youth-focused activities, co-designed with young people. The approach aimed at maximising engagement and reducing alcohol-related harm by targeting the shared activities and drinking practices of young people, parents and the community. Participants: Participants (n = 446) provided feedback specific to three key program activities for promoting alcohol change. Design: Mixed methods: Feedback sheets were collected, and interviews and focus groups were conducted with program participants. Results: Participants indicated that the program had informed their understanding of the way people in their region drink, and the social norms and practices around alcohol that encourage risky drinking. It influenced their short- and medium-term reactions, learnings and activities relating to alcohol consumption. The impact of the program was greatest in adults than young people although reflective learning and some behaviour change were evident across all age groups and community clusters. Conclusion: Community-wide health promotion events offer participants a deeper understanding of the ways in which dominant alcohol cultures inform the practices and activities of young people within a broader community context. Ensuring health promotion programs within a whole-of-community approach are established longer term, is recommended. © 2022 The Authors. Australian Journal of Rural Health published by John Wiley & Sons Australia, Ltd on behalf of National Rural Health Alliance Ltd.
- Lu, Kui, Sultan, Ibrahim, Phung, Truong
- Authors: Lu, Kui , Sultan, Ibrahim , Phung, Truong
- Date: 2023
- Type: Text , Journal article
- Relation: International Journal of Refrigeration Vol. 145, no. (2023), p. 467-480
- Full Text: false
- Reviewed:
- Description: As an emerging technology, the limaçon rotary compressor possesses great potential for fluid-processing applications. However, the technology and associated cost required to fabricate the limaçon machine could sometimes be beyond the capability of some manufacturers. To reduce the production cost, circolimaçon embodiment whose rotor and housing are constructed of circular arcs has been proposed. This paper is intended to investigate the viability of the circolimaçon embodiment of limaçon technology based on sealing performance. A nonlinear three-degree of freedom model is presented to describe the dynamic behaviour of the apex seal during the machine operation. Additionally, the leakage through the seal-housing gap is formulated by considering the inertia and viscous effects on the flow. A numerical illustration is offered to compare the performance of the circolimaçon embodiment with that of the limaçon-to-limaçon (L2L) type machine at different pressure ratios and operating speeds. The effect of limaçon aspect ratio on the apex seal dynamics is also investigated. Based on the results, it is found that the circolimaçon embodiment exhibits comparable performance to the L2L-type machine, despite having more significant seal vibrations. The differences in the volumetric and isentropic efficiencies between the two machines are found within 8% and 3%, respectively. Additionally, it is also discovered that the circolimaçon compressor with a small capacity undergoes lower level of seal dynamics, suggesting a better machine reliability. © 2022
- Tan, Zhi, Ooi, Ean Hin, Chiew, Yeong, Foo, Ji, Ng, Eddie, Ooi, Ean Tat
- Authors: Tan, Zhi , Ooi, Ean Hin , Chiew, Yeong , Foo, Ji , Ng, Eddie , Ooi, Ean Tat
- Date: 2023
- Type: Text , Journal article
- Relation: Ultrasonics Vol. 131, no. (2023), p.
- Full Text: false
- Reviewed:
- Description: Sonothrombolysis is a technique that utilises ultrasound waves to excite microbubbles surrounding a clot. Clot lysis is achieved through mechanical damage induced by acoustic cavitation and through local clot displacement induced by acoustic radiation force (ARF). Despite the potential of microbubble-mediated sonothrombolysis, the selection of the optimal ultrasound and microbubble parameters remains a challenge. Existing experimental studies are not able to provide a complete picture of how ultrasound and microbubble characteristics influence the outcome of sonothrombolysis. Likewise, computational studies have not been applied in detail in the context of sonothrombolysis. Hence, the effect of interaction between the bubble dynamics and acoustic propagation on the acoustic streaming and clot deformation remains unclear. In the present study, we report for the first time the computational framework that couples the bubble dynamic phenomena with the acoustic propagation in a bubbly medium to simulate microbubble-mediated sonothrombolysis using a forward-viewing transducer. The computational framework was used to investigate the effects of ultrasound properties (pressure and frequency) and microbubble characteristics (radius and concentration) on the outcome of sonothrombolysis. Four major findings were obtained from the simulation results: (i) ultrasound pressure plays the most dominant role over all the other parameters in affecting the bubble dynamics, acoustic attenuation, ARF, acoustic streaming, and clot displacement, (ii) smaller microbubbles could contribute to a more violent oscillation and improve the ARF simultaneously when they are stimulated at higher ultrasound pressure, (iii) higher microbubbles concentration increases the ARF, and (iv) the effect of ultrasound frequency on acoustic attenuation is dependent on the ultrasound pressure. These results may provide fundamental insight that is crucial in bringing sonothrombolysis closer to clinical implementation. © 2023 Elsevier B.V.
A conceptual framework for externally-influenced agents: an assisted reinforcement learning review
- Bignold, Adam, Cruz, Francisco, Taylor, Matthew, Brys, Tim, Dazeley, Richard, Vamplew, Peter, Foale, Cameron
- Authors: Bignold, Adam , Cruz, Francisco , Taylor, Matthew , Brys, Tim , Dazeley, Richard , Vamplew, Peter , Foale, Cameron
- Date: 2023
- Type: Text , Journal article
- Relation: Journal of Ambient Intelligence and Humanized Computing Vol. 14, no. 4 (2023), p. 3621-3644
- Full Text:
- Reviewed:
- Description: A long-term goal of reinforcement learning agents is to be able to perform tasks in complex real-world scenarios. The use of external information is one way of scaling agents to more complex problems. However, there is a general lack of collaboration or interoperability between different approaches using external information. In this work, while reviewing externally-influenced methods, we propose a conceptual framework and taxonomy for assisted reinforcement learning, aimed at fostering collaboration by classifying and comparing various methods that use external information in the learning process. The proposed taxonomy details the relationship between the external information source and the learner agent, highlighting the process of information decomposition, structure, retention, and how it can be used to influence agent learning. As well as reviewing state-of-the-art methods, we identify current streams of reinforcement learning that use external information in order to improve the agent’s performance and its decision-making process. These include heuristic reinforcement learning, interactive reinforcement learning, learning from demonstration, transfer learning, and learning from multiple sources, among others. These streams of reinforcement learning operate with the shared objective of scaffolding the learner agent. Lastly, we discuss further possibilities for future work in the field of assisted reinforcement learning systems. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
- Authors: Bignold, Adam , Cruz, Francisco , Taylor, Matthew , Brys, Tim , Dazeley, Richard , Vamplew, Peter , Foale, Cameron
- Date: 2023
- Type: Text , Journal article
- Relation: Journal of Ambient Intelligence and Humanized Computing Vol. 14, no. 4 (2023), p. 3621-3644
- Full Text:
- Reviewed:
- Description: A long-term goal of reinforcement learning agents is to be able to perform tasks in complex real-world scenarios. The use of external information is one way of scaling agents to more complex problems. However, there is a general lack of collaboration or interoperability between different approaches using external information. In this work, while reviewing externally-influenced methods, we propose a conceptual framework and taxonomy for assisted reinforcement learning, aimed at fostering collaboration by classifying and comparing various methods that use external information in the learning process. The proposed taxonomy details the relationship between the external information source and the learner agent, highlighting the process of information decomposition, structure, retention, and how it can be used to influence agent learning. As well as reviewing state-of-the-art methods, we identify current streams of reinforcement learning that use external information in order to improve the agent’s performance and its decision-making process. These include heuristic reinforcement learning, interactive reinforcement learning, learning from demonstration, transfer learning, and learning from multiple sources, among others. These streams of reinforcement learning operate with the shared objective of scaffolding the learner agent. Lastly, we discuss further possibilities for future work in the field of assisted reinforcement learning systems. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
- Wang, Yanping, Wang, Xiaofen, Dai, Hong-Ning, Zhang, Xiaosong, Imran, Muhammad
- Authors: Wang, Yanping , Wang, Xiaofen , Dai, Hong-Ning , Zhang, Xiaosong , Imran, Muhammad
- Date: 2023
- Type: Text , Journal article
- Relation: IEEE Transactions on Industrial Informatics Vol. 19, no. 6 (2023), p. 7835-7847
- Full Text: false
- Reviewed:
- Description: Intelligent Transport Systems (ITS) have received growing attention recently driven by technical advances in Industrial Internet of Vehicles (IIoV). In IIoV, vehicles report traffic data to management infrastructures to achieve better ITS services. To ensure security and privacy, many anonymous authentication-enabled data reporting protocols are proposed. However, these protocols usually require a large number of preloaded pseudonyms or involve a costly and irrevocable group signature. Thus, they are not ready for realistic deployment due to large storage overhead, expensive computation costs, or absence of malicious users' revocation. To address these issues, we present a novel data reporting protocol for edge-assisted ITS in this paper, where the traffic data is sent to distributed edge nodes for local processing. Specifically, we propose a new anonymous authentication scheme fine-tuned to fulfill the needs of vehicular data reporting, which allows authenticated vehicles to report unlimited unlinkable messages to edge nodes without huge pseudonyms download and storage costs. Moreover, we designed an efficient certificate update scheme based on a bivariate polynomial function. In this way, malicious vehicles can be revoked with time complexity O(1). The security analysis demonstrates that our protocol satisfies source authentication, anonymity, unlinkability, traceability, revocability, nonframeability, and nonrepudiation. Further, extensive simulation results show that the performance of our protocol is greatly improved since the signature size is reduced by at least 8%, the computation costs in message signing and verification are reduced by at least 56% and 67%, respectively, and the packet loss rate is reduced by at least 14%. © 2005-2012 IEEE.
A depth-based hybrid approach for safe flight corridor generation in memoryless planning
- Nguyen, Thai, Murshed, Mamzur, Choudhury, Tanveer, Keogh, Kathleen, Kahandawa Appuhamillage, Gayan, Nguyen, Linh
- Authors: Nguyen, Thai , Murshed, Mamzur , Choudhury, Tanveer , Keogh, Kathleen , Kahandawa Appuhamillage, Gayan , Nguyen, Linh
- Date: 2023
- Type: Text , Journal article
- Relation: Sensors Vol. 23, no. 16 (2023), p.
- Full Text:
- Reviewed:
- Description: This paper presents a depth-based hybrid method to generate safe flight corridors for a memoryless local navigation planner. It is first proposed to use raw depth images as inputs in the learning-based object-detection engine with no requirement for map fusion. We then employ an object-detection network to directly predict the base of polyhedral safe corridors in a new raw depth image. Furthermore, we apply a verification procedure to eliminate any false predictions so that the resulting collision-free corridors are guaranteed. More importantly, the proposed mechanism helps produce separate safe corridors with minimal overlap that are suitable to be used as space boundaries for path planning. The average intersection of union (IoU) of corridors obtained by the proposed algorithm is less than 2%. To evaluate the effectiveness of our method, we incorporated it into a memoryless planner with a straight-line path-planning algorithm. We then tested the entire system in both synthetic and real-world obstacle-dense environments. The obtained results with very high success rates demonstrate that the proposed approach is highly capable of producing safe corridors for memoryless local planning. © 2023 by the authors.
- Authors: Nguyen, Thai , Murshed, Mamzur , Choudhury, Tanveer , Keogh, Kathleen , Kahandawa Appuhamillage, Gayan , Nguyen, Linh
- Date: 2023
- Type: Text , Journal article
- Relation: Sensors Vol. 23, no. 16 (2023), p.
- Full Text:
- Reviewed:
- Description: This paper presents a depth-based hybrid method to generate safe flight corridors for a memoryless local navigation planner. It is first proposed to use raw depth images as inputs in the learning-based object-detection engine with no requirement for map fusion. We then employ an object-detection network to directly predict the base of polyhedral safe corridors in a new raw depth image. Furthermore, we apply a verification procedure to eliminate any false predictions so that the resulting collision-free corridors are guaranteed. More importantly, the proposed mechanism helps produce separate safe corridors with minimal overlap that are suitable to be used as space boundaries for path planning. The average intersection of union (IoU) of corridors obtained by the proposed algorithm is less than 2%. To evaluate the effectiveness of our method, we incorporated it into a memoryless planner with a straight-line path-planning algorithm. We then tested the entire system in both synthetic and real-world obstacle-dense environments. The obtained results with very high success rates demonstrate that the proposed approach is highly capable of producing safe corridors for memoryless local planning. © 2023 by the authors.
A fully automated self-help biopsychosocial transdiagnostic digital intervention to reduce anxiety and/or depression and improve emotional regulation and well-being: pre-follow-up single-arm feasibility trial
- Klein, Britt, Nguyen, Huy, McLaren, Suzanne, Andrews, Brooke, Shandley, Kerrie
- Authors: Klein, Britt , Nguyen, Huy , McLaren, Suzanne , Andrews, Brooke , Shandley, Kerrie
- Date: 2023
- Type: Text , Journal article
- Relation: JMIR Formative Research Vol. 7, no. (2023), p.
- Full Text:
- Reviewed:
- Description: Background: Anxiety disorders and depression are prevalent disorders with high comorbidity, leading to greater chronicity and severity of symptoms. Given the accessibility to treatment issues, more evaluation is needed to assess the potential benefits of fully automated self-help transdiagnostic digital interventions. Innovating beyond the current transdiagnostic one-size-fits-all shared mechanistic approach may also lead to further improvements. Objective: The primary objective of this study was to explore the preliminary effectiveness and acceptability of a new fully automated self-help biopsychosocial transdiagnostic digital intervention (Life Flex) aimed at treating anxiety and/or depression, as well as improving emotional regulation; emotional, social, and psychological well-being; optimism; and health-related quality of life. Methods: This was a real-world pre-during-post-follow-up feasibility trial design evaluation of Life Flex. Participants were assessed at the preintervention time point (week 0), during intervention (weeks 3 and 5), at the postintervention time point (week 8), and at 1- and 3-month follow-ups (weeks 12 and 20, respectively). Results: The results provided early support for the Life Flex program in reducing anxiety (Generalized Anxiety Disorder 7), depression (Patient Health Questionnaire 9), psychological distress (Kessler 6), and emotional dysregulation (Difficulties in Emotional Regulation 36) and increasing emotional, social, and psychological well-being (Mental Health Continuum-Short Form); optimism (Revised Life Orientation Test); and health-related quality of life (EQ-5D-3L Utility Index and Health Rating; all false discovery rate [FDR] < .001). Large within-group treatment effect sizes (range |d|=0.82 to 1.33) were found for most variables from pre- to postintervention assessments and at the 1- and 3-month follow-up. The exceptions were medium treatment effect sizes for EQ-5D-3L Utility Index (range Cohen d=
- Authors: Klein, Britt , Nguyen, Huy , McLaren, Suzanne , Andrews, Brooke , Shandley, Kerrie
- Date: 2023
- Type: Text , Journal article
- Relation: JMIR Formative Research Vol. 7, no. (2023), p.
- Full Text:
- Reviewed:
- Description: Background: Anxiety disorders and depression are prevalent disorders with high comorbidity, leading to greater chronicity and severity of symptoms. Given the accessibility to treatment issues, more evaluation is needed to assess the potential benefits of fully automated self-help transdiagnostic digital interventions. Innovating beyond the current transdiagnostic one-size-fits-all shared mechanistic approach may also lead to further improvements. Objective: The primary objective of this study was to explore the preliminary effectiveness and acceptability of a new fully automated self-help biopsychosocial transdiagnostic digital intervention (Life Flex) aimed at treating anxiety and/or depression, as well as improving emotional regulation; emotional, social, and psychological well-being; optimism; and health-related quality of life. Methods: This was a real-world pre-during-post-follow-up feasibility trial design evaluation of Life Flex. Participants were assessed at the preintervention time point (week 0), during intervention (weeks 3 and 5), at the postintervention time point (week 8), and at 1- and 3-month follow-ups (weeks 12 and 20, respectively). Results: The results provided early support for the Life Flex program in reducing anxiety (Generalized Anxiety Disorder 7), depression (Patient Health Questionnaire 9), psychological distress (Kessler 6), and emotional dysregulation (Difficulties in Emotional Regulation 36) and increasing emotional, social, and psychological well-being (Mental Health Continuum-Short Form); optimism (Revised Life Orientation Test); and health-related quality of life (EQ-5D-3L Utility Index and Health Rating; all false discovery rate [FDR] < .001). Large within-group treatment effect sizes (range |d|=0.82 to 1.33) were found for most variables from pre- to postintervention assessments and at the 1- and 3-month follow-up. The exceptions were medium treatment effect sizes for EQ-5D-3L Utility Index (range Cohen d=
- Ollerenshaw, Alison, Camilleri, Margaret
- Authors: Ollerenshaw, Alison , Camilleri, Margaret
- Date: 2023
- Type: Text , Journal article
- Relation: Australian Journal of Primary Health Vol. 29, no. 5 (2023), p. 422-427
- Full Text: false
- Reviewed:
- Description: Health justice partnerships (HJP) are innovative models for delivering integrated health and legal services to people experiencing complex issues. An HJP was established in regional Victoria, Australia, for young people. Promoting the program to young people and workers was essential for program uptake. There is a dearth of published information about strategies that support program promotion for young people and workers. In this practice and innovation paper, three promotional strategies were employed: a dedicated program website, secondary consultations, and legal education and information sessions. Each strategy is examined, with information presented about why and how these strategies were implemented alongside this HJP. The strengths and limitations of each strategy are explored, with some strategies appearing to engage audiences with the program more than others. The insights about each of the strategies established for this program may inform other HJPs with their planning and implementation for increased program awareness. © 2023 The Author(s) (or their employer(s)).
A hydrogen supply-chain model powering Australian isolated communities
- Hasan, Tanvir, Hassan, Nur, Shah, Rakibuzzaman, Emami, Kianoush, Anderson, Jake
- Authors: Hasan, Tanvir , Hassan, Nur , Shah, Rakibuzzaman , Emami, Kianoush , Anderson, Jake
- Date: 2023
- Type: Text , Journal article
- Relation: Energy Reports Vol. 9, no. (2023), p. 209-214
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- Description: This article proposes a supply chain-based green hydrogen microgrid modelling for a number of remote Australian communities. Green hydrogen can be used as an emissions-free fuel source for electricity generation in places where large-scale renewable energy production is impossible due to land availability, population, or government regulations. This research focuses on the Torres Strait Island communities in northern Australia, where the transition from diesel to renewable electricity generation is difficult due to very limited land availability on most islands. Due to geographical constraints, low population and smaller electrical load, the green hydrogen needs to be sourced from somewhere else. This research presents a green hydrogen supply chain model that leverages the land availability of one island to produce hydrogen to supply other island communities. In addition, this research presents a model of producing and transporting green hydrogen while supplying cheaper electricity to the communities at focus. The study has used a transitional scenario planning approach and the HOMER simulation platform to find the least-cost solution. Based on the results, a levelised cost of energy range of AU$0.42 and AU$0.44 was found. With the help of a green hydrogen supply chain, CO2 emissions at the selected sites could be cut by 90 %. This study can be used as a guide for small clustered communities that could not support or justify large-scale renewable generation facilities but need more opportunities to install renewable generation. © 2023
- Authors: Hasan, Tanvir , Hassan, Nur , Shah, Rakibuzzaman , Emami, Kianoush , Anderson, Jake
- Date: 2023
- Type: Text , Journal article
- Relation: Energy Reports Vol. 9, no. (2023), p. 209-214
- Full Text:
- Reviewed:
- Description: This article proposes a supply chain-based green hydrogen microgrid modelling for a number of remote Australian communities. Green hydrogen can be used as an emissions-free fuel source for electricity generation in places where large-scale renewable energy production is impossible due to land availability, population, or government regulations. This research focuses on the Torres Strait Island communities in northern Australia, where the transition from diesel to renewable electricity generation is difficult due to very limited land availability on most islands. Due to geographical constraints, low population and smaller electrical load, the green hydrogen needs to be sourced from somewhere else. This research presents a green hydrogen supply chain model that leverages the land availability of one island to produce hydrogen to supply other island communities. In addition, this research presents a model of producing and transporting green hydrogen while supplying cheaper electricity to the communities at focus. The study has used a transitional scenario planning approach and the HOMER simulation platform to find the least-cost solution. Based on the results, a levelised cost of energy range of AU$0.42 and AU$0.44 was found. With the help of a green hydrogen supply chain, CO2 emissions at the selected sites could be cut by 90 %. This study can be used as a guide for small clustered communities that could not support or justify large-scale renewable generation facilities but need more opportunities to install renewable generation. © 2023
A literature review of the positive displacement compressor : current challenges and future opportunities
- Lu, Kui, Sultan, Ibrahim, Phung, Truong
- Authors: Lu, Kui , Sultan, Ibrahim , Phung, Truong
- Date: 2023
- Type: Text , Journal article , Review
- Relation: Energies Vol. 16, no. 20 (2023), p.
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- Description: Positive displacement compressors are essential in many engineering systems, from domestic to industrial applications. Many studies have been devoted to providing more insights into the workings and proposing solutions for performance improvements of these machines. This study aims to present a systematic review of published research on positive displacement compressors of various geometrical structures. This paper discusses the literature on compressor topics, including leakage, heat transfer, friction and lubrication, valve dynamics, port characteristics, and capacity control strategies. Moreover, the current status of the application of machine learning methods in positive displacement compressors is also discussed. The challenges and opportunities for future work are presented at the end of the paper. © 2023 by the authors.
- Authors: Lu, Kui , Sultan, Ibrahim , Phung, Truong
- Date: 2023
- Type: Text , Journal article , Review
- Relation: Energies Vol. 16, no. 20 (2023), p.
- Full Text:
- Reviewed:
- Description: Positive displacement compressors are essential in many engineering systems, from domestic to industrial applications. Many studies have been devoted to providing more insights into the workings and proposing solutions for performance improvements of these machines. This study aims to present a systematic review of published research on positive displacement compressors of various geometrical structures. This paper discusses the literature on compressor topics, including leakage, heat transfer, friction and lubrication, valve dynamics, port characteristics, and capacity control strategies. Moreover, the current status of the application of machine learning methods in positive displacement compressors is also discussed. The challenges and opportunities for future work are presented at the end of the paper. © 2023 by the authors.
A longitudinal study on a place-based school-university partnership : listening to the voices of in-service teachers
- Authors: Ma, Hongming , Green, Monica
- Date: 2023
- Type: Text , Journal article
- Relation: Teaching and Teacher Education Vol. 129, no. (2023), p.
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- Description: This paper reports on a longitudinal place-based study by two Australian teacher educators investigating their three-year science-based school-university partnership. The study examined key benefits, challenges, and tensions within the partnership. Data collection was drawn from focus group interviews with in-service teachers across each partnership year. While findings portray the partnership as a catalyst for increased science learning opportunities for school students, teaching opportunities for pre-service teachers, and new in-service teacher roles and responsibilities, the study highlights the evolving nature of partnership development, including the need for continuous negotiation of labor division and stakeholder expectations. © 2023 The Authors
- Authors: Ma, Hongming , Green, Monica
- Date: 2023
- Type: Text , Journal article
- Relation: Teaching and Teacher Education Vol. 129, no. (2023), p.
- Full Text:
- Reviewed:
- Description: This paper reports on a longitudinal place-based study by two Australian teacher educators investigating their three-year science-based school-university partnership. The study examined key benefits, challenges, and tensions within the partnership. Data collection was drawn from focus group interviews with in-service teachers across each partnership year. While findings portray the partnership as a catalyst for increased science learning opportunities for school students, teaching opportunities for pre-service teachers, and new in-service teacher roles and responsibilities, the study highlights the evolving nature of partnership development, including the need for continuous negotiation of labor division and stakeholder expectations. © 2023 The Authors
- Yu, Kelai, Yang, Zhenjun, Li, Hui, Ooi, Ean Tat, Li, Shangming, Liu, GuoHua
- Authors: Yu, Kelai , Yang, Zhenjun , Li, Hui , Ooi, Ean Tat , Li, Shangming , Liu, GuoHua
- Date: 2023
- Type: Text , Journal article
- Relation: Engineering Fracture Mechanics Vol. 278, no. (2023), p.
- Full Text: false
- Reviewed:
- Description: This study develops an innovative numerical approach for simulating complex mesoscale fracture in concrete. In this approach, the concrete meso-structures are generated using a random aggregate generation and packing algorithm. Each aggregate is modelled by a single scaled boundary finite element method (SBFEM) based polygon with the boundary discretized only. The damage and fracture in the mortar is simulated by the continuous damage phase-field regularized cohesive zone model (PF-CZM), and the aggregate-mortar interfaces are modelled by zero-thickness cohesive interface elements (CIEs) with nonlinear softening separation-traction laws. This new approach thus takes full advantages of different methods, including the semi-analytical accuracy and high flexibility in mesh generation and transition of SBFEM, the mesh and length-scale independence of PF-CZM, and the ease-of-use of CIEs in modelling discrete interfacial fracture. These advantages are demonstrated by successful simulations of a few 2D and 3D benchmark examples in mode-I and mixed-mode fracture. © 2022 Elsevier Ltd
A multi-layered approach to developing academic written communication skills for nursing students
- Garvey, Loretta, Willetts, Georgina, Herrmann, Antje, Verezub, Elena, Sinchenko, Elena
- Authors: Garvey, Loretta , Willetts, Georgina , Herrmann, Antje , Verezub, Elena , Sinchenko, Elena
- Date: 2023
- Type: Text , Journal article
- Relation: International Journal of Nursing Education Scholarship Vol. 20, no. 1 (2023), p.
- Full Text: false
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- Description: Objectives: Academic literacy in nursing students has historically been poor this research therefore aimed to investigate the effectiveness of an embedded multidisciplinary approach to academic written communication skills for first year Bachelor of Nursing students in Australia. Methods: This initiative consisted of (1) collaboratively embedding academic skills with nursing staff and Learning and Academic Skills Advisors using scaffolded tasks, curriculum/material development, workshops/tutorials on writing skills; and (2) individual support sessions. Data was obtained via questionnaire. Results: Responses were received from 92 (74% local and 26% international) students. Key findings showed the collaborative approach to embedding skills with added follow up, was beneficial for students' skills development, including improved academic writing, increased confidence, and recognition of the importance of academic writing. Conclusions: It is important to equip student to develop academic literacy and an embedded academic literacy program has been determined to assist and may contribute to future professionalisation in nursing. © 2023 Walter de Gruyter GmbH, Berlin/Boston.
A nethack learning environment language wrapper for autonomous agents
- Goodger, Nikolaj, Vamplew, Peter, Foale, Cameron, Dazeley, Richard
- Authors: Goodger, Nikolaj , Vamplew, Peter , Foale, Cameron , Dazeley, Richard
- Date: 2023
- Type: Text , Journal article
- Relation: Journal of Open Research Software Vol. 11, no. (2023), p.
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- Description: This paper describes a language wrapper for the NetHack Learning Environment (NLE) [1]. The wrapper replaces the non-language observations and actions with comparable language versions. The NLE offers a grand challenge for AI research while MiniHack [2] extends this potential to more specific and configurable tasks. By providing a language interface, we can enable further research on language agents and directly connect language models to a versatile environment. © 2023 The Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See http://creativecommons.org/licenses/by/4.0/.
- Authors: Goodger, Nikolaj , Vamplew, Peter , Foale, Cameron , Dazeley, Richard
- Date: 2023
- Type: Text , Journal article
- Relation: Journal of Open Research Software Vol. 11, no. (2023), p.
- Full Text:
- Reviewed:
- Description: This paper describes a language wrapper for the NetHack Learning Environment (NLE) [1]. The wrapper replaces the non-language observations and actions with comparable language versions. The NLE offers a grand challenge for AI research while MiniHack [2] extends this potential to more specific and configurable tasks. By providing a language interface, we can enable further research on language agents and directly connect language models to a versatile environment. © 2023 The Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See http://creativecommons.org/licenses/by/4.0/.
A new era of integration between multiomics and spatio-temporal analysis for the translation of EMT towards clinical applications in cancer
- Fonseca Teixeira, Adilson, Wu, Siqi, Luwor, Rodney, Zhu, Hong-Jian
- Authors: Fonseca Teixeira, Adilson , Wu, Siqi , Luwor, Rodney , Zhu, Hong-Jian
- Date: 2023
- Type: Text , Journal article , Review
- Relation: Cells Vol. 12, no. 23 (2023), p.
- Full Text:
- Reviewed:
- Description: Epithelial-mesenchymal transition (EMT) is crucial to metastasis by increasing cancer cell migration and invasion. At the cellular level, EMT-related morphological and functional changes are well established. At the molecular level, critical signaling pathways able to drive EMT have been described. Yet, the translation of EMT into efficient diagnostic methods and anti-metastatic therapies is still missing. This highlights a gap in our understanding of the precise mechanisms governing EMT. Here, we discuss evidence suggesting that overcoming this limitation requires the integration of multiple omics, a hitherto neglected strategy in the EMT field. More specifically, this work summarizes results that were independently obtained through epigenomics/transcriptomics while comprehensively reviewing the achievements of proteomics in cancer research. Additionally, we prospect gains to be obtained by applying spatio-temporal multiomics in the investigation of EMT-driven metastasis. Along with the development of more sensitive technologies, the integration of currently available omics, and a look at dynamic alterations that regulate EMT at the subcellular level will lead to a deeper understanding of this process. Further, considering the significance of EMT to cancer progression, this integrative strategy may enable the development of new and improved biomarkers and therapeutics capable of increasing the survival and quality of life of cancer patients. © 2023 by the authors.
- Authors: Fonseca Teixeira, Adilson , Wu, Siqi , Luwor, Rodney , Zhu, Hong-Jian
- Date: 2023
- Type: Text , Journal article , Review
- Relation: Cells Vol. 12, no. 23 (2023), p.
- Full Text:
- Reviewed:
- Description: Epithelial-mesenchymal transition (EMT) is crucial to metastasis by increasing cancer cell migration and invasion. At the cellular level, EMT-related morphological and functional changes are well established. At the molecular level, critical signaling pathways able to drive EMT have been described. Yet, the translation of EMT into efficient diagnostic methods and anti-metastatic therapies is still missing. This highlights a gap in our understanding of the precise mechanisms governing EMT. Here, we discuss evidence suggesting that overcoming this limitation requires the integration of multiple omics, a hitherto neglected strategy in the EMT field. More specifically, this work summarizes results that were independently obtained through epigenomics/transcriptomics while comprehensively reviewing the achievements of proteomics in cancer research. Additionally, we prospect gains to be obtained by applying spatio-temporal multiomics in the investigation of EMT-driven metastasis. Along with the development of more sensitive technologies, the integration of currently available omics, and a look at dynamic alterations that regulate EMT at the subcellular level will lead to a deeper understanding of this process. Further, considering the significance of EMT to cancer progression, this integrative strategy may enable the development of new and improved biomarkers and therapeutics capable of increasing the survival and quality of life of cancer patients. © 2023 by the authors.