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Date: 2017
Type: Text
Identifier: http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/157634
Description: The genetics of blood pressure (BP) is all about discovery and understanding, but it is certainly not for the faint hearted. Despite heroic effort, the question we posed nearly 15 years ago [1] regard... More
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Date: 2017
Type: Text
Identifier: http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/158524
Description: Background This study examined a programme of pre-conditioning exercise with subsequent high intensity interval training (HIIT) on blood pressure, echocardiography, cardiac strain mechanics and maxima... More
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Date: 2017
Type: Text
Identifier: http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/156899
Description: Objective: To determine the effect of renal denervation (RDN) on the severity of atherosclerosis and aortic aneurysm in hypertensive mice. Methods: Hypertension, atherosclerosis and aortic aneurysm we... More
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Date: 2015
Type: Text
Identifier: http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/99374
Description: Unravelling the complete genetic predisposition to high blood pressure (BP) has proven to be challenging. This puzzle and the fact that coding regions of the genome account for less than 2 % of the en... More
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Date: 2015
Type: Text
Identifier: http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/100410
Description: The fibroblast growth factor 1 (FGF1) gene is expressed primarily in the kidney and may contribute to hypertension. However, the biologic mechanisms underlying the association between FGF1 and BP regu... More
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Date: 2015
Type: Text
Identifier: http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/102230
Description: MicroRNA-181a binds to the 3’ untranslated region of messenger RNA (mRNA) for renin, a rate-limiting enzyme of the renin-angiotensin system. Our objective was to determine whether this molecular inter... More
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Date: 2014
Type: Text
Identifier: http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/44661
Description: We provide new historical evidence on the developmental origins of health and disease in a cohort of boys born between 1907 and 1922 in Wellington, New Zealand. Using a dataset of 1523 birth records t... More
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Authors: Wang, Yutang
Date: 2014
Type: Text
Identifier: http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/76801
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Authors: Wang, Yutang
Date: 2014
Type: Text
Identifier: http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/76797
Description: Ewen et al. recently reported in the journal Hypertension that they investigated, for the first time, the effect of renal denerva tion on blood pressure in 63 patients with isolated systolic hypertens... More
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Date: 2014
Type: Text
Identifier: http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/92667
Description: Background: The role of copy number variation (CNV) has been poorly explored in essential hypertension in part due to technical difficulties in accurately assessing absolute numbers of DNA copies. Dro... More
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Date: 2013
Type: Text
Identifier: http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/66343
Description: Urotensin-II controls ion/water homeostasis in fish and vascular tone in rodents. We hypothesised that common genetic variants in urotensin-II pathway genes are associated with human blood pressure or... More
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Date: 2012
Type: Text
Identifier: http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/41667
Description: There is now good evidence for a role of the sympathetic nervous system in the etiology of essential hypertension in humans. Although genetic variation is expected to underlie the elevated sympathetic... More
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Date: 2010
Type: Text
Identifier: http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/58280
Description: Essential hypertension is a complex, multifactorial disease with a strong genetic component. Fibroblast growth factor 1 gene (FGF1) is one of the most relevant candidates having been associated not on... More
Date: 2010
Type: Text
Identifier: http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/63959
Description: Genetic determinants of blood pressure are poorly defined. We undertook a large-scale, gene-centric analysis to identify loci and pathways associated with ambulatory systolic and diastolic blood press... More
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Date: 2010
Type: Text
Identifier: http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/67976
Description: Copy number variation has emerged recently as an important genetic mechanism leading to phenotypic heterogeneity. The aim of our study was to determine whether copy number variants (CNVs) exist betwee... More
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