- Title
- Utility of the hypertriglyceridemic waist phenotype in the cardiometabolic risk assessment of youth stratified by body mass index
- Creator
- Buchan, Duncan; Boddy, Lynne; Despres, Jean; Grace, Fergal; Sculthorpe, Nicholas; Mahoney, Craig; Baker, Julien
- Date
- 2016
- Type
- Text; Journal article
- Identifier
- http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/157913
- Identifier
- vital:11673
- Identifier
-
https://doi.org/10.1111/ijpo.12061
- Identifier
- ISSN:2047-6302
- Abstract
- BACKGROUND: It is unclear whether the hypertriglyceridemic waist phenotype (HTWP) can be used to identify those at most risk of cardiometabolic disorders. OBJECTIVES: The utility of the HTWP as a useful predictor of cardiometabolic risk in youth stratified by body mass index was assessed. METHODS: Three hundred and eighty-seven children (12-17.5 years) were used within this cross-sectional study. Participants were classified as normal weight or overweight/obese according to the International Obesity Task Force criteria. The HTWP phenotype was defined as having a waist circumference >/=90th percentile for age and gender with concomitant triglyceride concentrations >/=1.24 mmol L(-1) . Cardiometabolic risk profiles were compared using MANCOVA. RESULTS: Normal weight participants with the HTWP had significantly higher levels of C-reactive protein 2.6 +/- 0.4 vs. 1.6 +/- 0.3 mg L(-1) (P < 0.05) and cardiometabolic risk scores (1.3 +/- 0.3 vs. -0.7 +/- 0.2 and 2.1 +/- 0.4 vs. -0.5 +/- 0.2; both P < 0.05) compared with those of a normal weight without the HTWP. Overweight/obese participants with the HTWP had significantly higher C-reactive protein levels (3.5 +/- 0.6 vs. 2.6 +/- 0.5; P < 0.05) as well as both cardiometabolic risk scores (1.6 +/- 0.6 vs. 0.9 +/- 0.2 and 2.2 +/- 0.6 vs. 0.8 +/- 0.2; both P < 0.001) when compared with overweight/obese participants without the HTWP. CONCLUSIONS: The HTWP may serve as a simple and clinically useful approach to identify youth at increased cardiometabolic risk.
- Relation
- Pediatric Obesity Vol. 11, no. 4 (2016), p. 292-298
- Rights
- © 2015 World Obesity.
- Rights
- This metadata is freely available under a CCO license
- Subject
- Adolescents; Cardiometabolic risk; Cardiorespiratory fitness; Hypertriglyceridemic waist phenotype
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