The kinetics of local cytokine and galectin expression after challenge infection with the gastrointestinal nematode, Haemonchus contortus

Title: The kinetics of local cytokine and galectin expression after challenge infection with the gastrointestinal nematode, Haemonchus contortus
Creator: Robinson, Nicholas; Pleasance, Jill; Piedrafita, David; Meeusen, Els
Date: 2011
Type: Text; Journal article
Identifier: http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/70644
Identifier: vital:6538
Identifier: https://doi.org/10.1016/j.ijpara.2010.11.006
Identifier: ISSN:0020-7519
Abstract: Gastrointestinal nematode parasites undergo several developmental stages within their mammalian host, each presenting different antigenic challenges to the immune system. To examine the expression of different immune mediators over time, biopsy samples were collected from the cannulated abomasum (true stomach) of immune sheep at several times after a challenge infection with Haemonchus contortus L3s. IL-5 and IL-13 mRNA expression levels were significantly increased above saline-challenged control levels at 5 and 7 days post challenge, while IL-4 showed an earlier peak at day 2 post challenge. IL-5, IL-13 and IL-4, as well as IFN-
Relation: International Journal for Parasitology Vol. 41, no. 5 (2011 2011), p. 487-493
Rights: Copyright Elsevier
Rights: This metadata is freely available under a CCO license
Subject: 0605 Microbiology; 0608 Zoology; 0707 Veterinary Sciences; Gastrointestinal nematode; Biopsy; Cytokine; Galectin; Helminth
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