- Title
- Human cardiac autonomic responses to head up tilting during 72-h starvation
- Creator
- Brown, Stephen; Bryant, Michelle; Mundel, Toby; Stannard, Stephen
- Date
- 2012
- Type
- Text; Journal article
- Identifier
- http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/72630
- Identifier
- vital:6951
- Identifier
-
https://doi.org/10.1007/s00421-011-2207-6
- Identifier
- ISSN:1439-6319
- Abstract
- Starvation may change autonomic nervous system activity and sensitivity such that a greater vagal withdrawal may occur during a sympathetic challenge. Six healthy humans endured a 3-day, water-only fast, during which participants were subjected to passive 80° head-up tilt testing twice on each day (a.m. and p.m.). Heart rate, heart rate variability (HRV), ventilation (V′E), and respiration ( V′O2 and V′CO2) were recorded during supine rest and head-up tilting. On Day 1 (a.m.), supine heart rate was 46.0 ± 3.3 beats min−1, increasing to 51.6 ± 7.4 beats min−1 on Day 3 (p.m.). On Day 1 (a.m.), supine high frequency HRV was 57.9 ± 31.6NU, increasing to 69.5 ± 21.3NU on Day 3 (p.m.). Tilt-induced increases in heart rate were greater following starvation (10.5 ± 7.8 vs. 16.1 ± 8.6 beats min−1), and tilt-induced decreases in high frequency HRV were greater following starvation (−4.1 ± 27.7 vs. −28.0 ± 20.8NU). Supine V′CO2 remained unchanged, whereas V′O2 increased and respiratory exchange ratio decreased (0.91 ± 0.10 vs. 0.80 ± 0.05). Greater vagal withdrawal and elevated heart rate induced by head-up tilting during starvation may indicate increased autonomic sensitivity.
- Relation
- European Journal of Applied Physiology Vol. 112, no. 6 (2012), p. 2331-2339
- Rights
- Copyright Springer
- Rights
- This metadata is freely available under a CCO license
- Subject
- 1106 Human Movement and Sports Science; Receptor antagonist; Receptor agonist; Receptor subtype; Amino acid; Placebo group; Drug dose; Rat brain
- Reviewed
- Hits: 683
- Visitors: 670
- Downloads: 0
| Thumbnail | File | Description | Size | Format |
|---|