- Title
- Acetaldehyde mediates growth stimulation of ethanol-stressed Saccharomyces cerevisiae: Evidence of a redox-driven mechanism
- Creator
- Vriesekoop, Frank; Barber, Andrew; Pamment, Neville
- Date
- 2007
- Type
- Text; Journal article
- Identifier
- http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/45675
- Identifier
- vital:913
- Identifier
-
https://doi.org/10.1007/s10529-007-9367-9
- Identifier
- ISSN:0141-5492
- Abstract
- The ability of acetaldehyde (90 mg l-1) to stimulate ethanol-stressed S. cerevisiae fermentations is examined and reasons for the effect explored. Alternative metabolic electron acceptors generated similar stimulatory effects to acetaldehyde, decreasing the ethanol-induced growth lag phase from 9 h to 3 h, suggesting a redox-driven effect. The exposure to ethanol caused an instant 60% decline in intracellular NAD+ which was largely prevented by the addition of acetaldehyde. Furthermore, the exposure to ethanol affected glycolysis by decreasing the rate of glucose utilisation from 0.33 g glucose g-1 biomass h-1 to 0.11 g glucose g -1 biomass h-1, while the addition of acetaldehyde to an ethanol stressed culture increased this rate to 0.14 g glucose g-1 biomass h-1. © 2007 Springer Science+Business Media B.V.; C1
- Publisher
- Springer
- Relation
- Biotechnology Letters Vol. 29, no. 7 (2007), p. 1099-1103
- Rights
- Copyright Springer
- Rights
- This metadata is freely available under a CCO license
- Subject
- 10 Technology; Acetaldehyde; Electron acceptor; Ethanol; Glycolysis; Redox balance; Yeast
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