Antimicrobial resistance in community and nosocomial Escherichia coli urinary tract isolates, London 2005-2006

Bean, David; Krahe, Daniel; Wareham, David

Title: Antimicrobial resistance in community and nosocomial Escherichia coli urinary tract isolates, London 2005-2006
Creator: Bean, David; Krahe, Daniel; Wareham, David
Date: 2008
Type: Text; Journal article
Identifier: http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/74092
Identifier: vital:7153
Identifier: https://doi.org/10.1186/1476-0711-7-13
Identifier: ISSN:1476-0711
Abstract: Background: Escherichia coli is the commonest cause of community and nosocomial urinary tract infection (UTI). Antibiotic treatment is usually empirical relying on susceptibility data from local surveillance studies. We therefore set out to determine levels of resistance to 8 commonly used antimicrobial agents amongst all urinary isolates obtained over a 12 month period. Methods: Antimicrobial susceptibility to ampicillin, amoxicillin/ clavulanate, cefalexin, ciprofloxacin, gentamicin, nitrofurantoin, trimethoprim and cefpodoxime was determined for 11,865 E. coli urinary isolates obtained from community and hospitalised patients in East London. Results: Nitrofurantoin was the most active agent (94% susceptible), followed by gentamicin and cefpodoxime. High rates of resistance to ampicillin (55%) and trimethoprim (40%), often in combination were observed in both sets of isolates. Although isolates exhibiting resistance to multiple drug classes were rare, resistance to cefpodoxime, indicative of Extended spectrum; C1
Relation: Annals of Clinical Microbiology and Antimicrobials Vol. 7, no. (June 2008 2008), p.
Rights: Open access
Rights: This metadata is freely available under a CCO license
Subject: 1103 Clinical Sciences
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