- Title
- Longer leukocyte telomeres are associated with ultra-endurance exercise independent of cardiovascular risk factors
- Creator
- Denham, Joshua; Nelson, Christopher; O'Brien, Brendan; Nankervis, Scott; Denniff, Matthew; Harvey, Jack; Marques, Francine; Codd, Veryan; Zukowska-Szczechowska, Ewa; Samani, Nilesh; Tomaszewski, Maciej; Charchar, Fadi
- Date
- 2013
- Type
- Text; Journal article
- Identifier
- http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/36059
- Identifier
- vital:5126
- Identifier
-
https://doi.org/10.1371/journal.pone.0069377
- Identifier
- ISSN:1932-6203
- Abstract
- Telomere length is recognized as a marker of biological age, and shorter mean leukocyte telomere length is associated with increased risk of cardiovascular disease. It is unclear whether repeated exposure to ultra-endurance aerobic exercise is beneficial or detrimental in the long-term and whether it attenuates biological aging. We quantified 67 ultra-marathon runners' and 56 apparently healthy males' leukocyte telomere length (T/S ratio) using real-time quantitative PCR. The ultra-marathon runners had 11% longer telomeres (T/S ratio) than controls (ultra-marathon runners: T/S ratio = 3.5±0.68, controls: T/S ratio = 3.1±0.41;
- Relation
- PLoS ONE Vol. 8, no. 7 (2013), p.
- Rights
- Copyright 2013 Denham et al.
- Rights
- Open Access
- Rights
- This metadata is freely available under a CCO license
- Subject
- MD Multidisciplinary; Longer leukocyte telomeres; Ultra-Endurance Exercise; Cardiovascular risk factors
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