- Title
- An optimization approach to the study of drug-drug interactions
- Creator
- Mammadov, Musa; Banerjee, Arunava
- Date
- 2005
- Type
- Text; Conference paper
- Identifier
- http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/63938
- Identifier
- vital:3771
- Identifier
- ISBN:0646452525
- Abstract
- Drug-drug interaction is one of the important problems of Adverse Drug Reaction (ADR). In this paper we develop an optimization approach for the study of this problem. This approach is based on drug-reaction relationships represented in the form of a vector of weights, which can be defined as a solution to some global optimization problem. Although this approach can be used for solving many ADR problems, we concentrate here only on drug-drug interactions. Based on drug-reaction relationships, we formulate this problem as an optimization problem. The approach is applied to different classes of reactions from the Australian Adverse Drug Reaction Advisory Committee (ADRAC) database.
- Publisher
- Ballarat, Victoria : University of Ballarat
- Relation
- Paper pesented at Sixteenth Australasian Workshop on Combinatorial Algorithms, AWOCA 2005, Ballarat, Victoria : 18th-21st September 2005 p. 201-216
- Rights
- Open Access
- Rights
- This metadata is freely available under a CCO license
- Subject
- 0802 Computation Theory and Mathematics; Global optimization; Adverse drug reaction; Multi-label classification; Drug-drug interaction
- Full Text
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