- Title
- Supportive-expressive group therapy for women with metastatic breast cancer : Survival and psychosocial outcome from a randomized controlled trial
- Creator
- Kissane, David; Grabsch, Brenda; Clarke, David; Smith, Graeme; Love, Anthony; Bloch, Sidney; Snyder, Raymond; Li, Yuellin
- Date
- 2007
- Type
- Text; Journal article
- Identifier
- http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/60799
- Identifier
- vital:3030
- Identifier
-
https://doi.org/10.1002/pon.1185
- Identifier
- ISSN:1057-9249
- Abstract
- Background: Mixed reports exist about the impact of supportive-expressive group therapy (SEGT) on survival. Methods: From 485 women with advanced breast cancer recruited between 1996-2002, 227 (47%) consented and were randomized within an average 10 months of cancer recurrence in a 2:1 ratio to intervention with 1 year or more of weekly SEGT plus three classes of relaxation therapy (147 women) or to control receiving three classes of relaxation therapy (80 women). The primary outcome was survival; psychosocial well-being was appraised secondarily. Analysis was by intention-to-treat. Results: SEGT did not prolong survival (median survival 24.0 months in SEGT and 18.3 in controls; univariate hazard ratio for death 0.92 [95% CI, 0.69-1.26]; multivariate hazard ratio, 1.06 [95% CI, 0.74-1.51]). Significant predictors of survival were treatment with chemotherapy and hormone therapy (p<0.001), visceral metastases (p<0.001) and advanced disease at first diagnosis (p<0.05). SEGT ameliorated and prevented new DSM-IV depressive disorders (p = 0.002), reduced hopeless-helplessness (p = 0.004), trauma symptoms (p = 0.04) and improved social functioning (p = 0.03). Conclusions: SEGT did not prolong survival. It improved quality of life, including treatment of and protection against depression. Copyright © 2007 John Wiley & Sons, Ltd.; C1
- Publisher
- Wiley
- Relation
- Psycho-Oncology Vol. 16, no. 4 (2007), p. 277-286
- Rights
- Copyright John Wiley & Sons
- Rights
- This metadata is freely available under a CCO license
- Subject
- 1112 Oncology and Carcinogenesis; 1701 Psychology; Breast cancer; Group therapy; Survival; Depression; Psychosocial outcome
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