- Title
- Effects of 12-week supervised early resistance training (SEcReT) versus aerobic-based rehabilitation on cognitive recovery following cardiac surgery via median sternotomy : a pilot randomised controlled trial
- Creator
- Pengelly, Jacqueline; Royse, Colin; Williams, Gavin; Bryant, Adam; Clarke-Errey, Sandy; Royse, Alistair; El-Ansary, Doa
- Date
- 2022
- Type
- Text; Journal article
- Identifier
- http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/187219
- Identifier
- vital:17059
- Identifier
-
https://doi.org/10.1016/j.hlc.2021.08.023
- Identifier
- ISBN:1443-9506 (ISSN)
- Abstract
- Aims: To investigate the effects of a 12-week early moderate-intensity resistance training program compared to aerobic-based rehabilitation on postoperative cognitive recovery following cardiac surgery via median sternotomy. Methods: This was a multicentre, prospective, pragmatic, non-blinded, pilot randomised controlled trial (1:1 randomisation) of two parallel groups that compared a 12-week early moderate-intensity resistance training group to a control group, receiving aerobic-based rehabilitation. English-speaking adults (≥18 years) undergoing elective cardiac surgery via median sternotomy were randomised using sealed envelopes, with allocation revealed before surgery. The primary outcome was cognitive function, assessed using the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog), at baseline, 14 weeks and 6 months postoperatively. Results: The ADAS-cog score at 14 weeks was significantly better for the resistance training group (n=14, 7.2±1.4; 95% CI 4.3, 10.2, vs n=17, 9.2±1.3; 95% CI 6.6, 11.9, p=0.010). At 14 weeks postoperatively, 53% of the aerobic-based rehabilitation group (n=9/17) experienced cognitive decline by two points or more from baseline ADAS-cog score, compared to 0% of the resistance training group (n=0/14; p=0.001). Conclusion: Early resistance training appears to be safe and may improve cognitive recovery compared to standard, aerobic-based rehabilitation following cardiac surgery via median sternotomy, however as this was a pilot study, the sample size was small and further research is needed to determine a causal relationship. © 2021 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ)
- Publisher
- Elsevier Ltd
- Relation
- Heart Lung and Circulation Vol. 31, no. 3 (2022), p. 395-406
- Rights
- All metadata describing materials held in, or linked to, the repository is freely available under a CC0 licence
- Rights
- Copyright © 2021 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ)
- Subject
- 3201 Cardiovascular medicine and haematology; 4203 Health services and systems; 4206 Public health; Cardiac rehabilitation; Cardiac surgery; Cognition; Cognitive impairment; Exercise; Resistance training
- Reviewed
- Funder
- Department of Surgery Seeding Grant, University of Melbourne.Jacqueline Pengelly is supported by a Research Training Stipend, Swinburne University of Technology.
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