- Title
- The effect of moxonidine on atherosclerosis
- Creator
- Nguyen, Dinh
- Date
- 2022
- Type
- Text; Thesis; PhD
- Identifier
- http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/184069
- Identifier
- vital:16422
- Abstract
- Background: Atherosclerosis is an inflammatory disease with hypertension as a risk factor. Moxonidine decreases blood pressure and has an anti-inflammatory effect. Aim: To investigate the effect of moxonidine on atherosclerosis: Key methods and results: For the in vivo experiment, twenty male apolipoprotein E-deficient mice were randomized into two groups: the control and moxonidine treatment groups. The mice from the moxonidine treatment group were treated with moxonidine via drinking water (69 mg/L) which equated to a dose of 18 mg/kg body weight per day, whereas the mice from the control group received normal drinking water without moxonidine. All the mice received angiotensin II (1; Doctor of Philosophy
- Publisher
- Federation University Australia
- Rights
- All metadata describing materials held in, or linked to, the repository is freely available under a CC0 licence
- Rights
- Copyright Dinh Tam Nguyen
- Rights
- Open Access
- Subject
- Moxonidine; Atherosclerosis; Inflammation; Low-density lipoprotein
- Full Text
- Thesis Supervisor
- Wang, Yutang
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