- Title
- Evaluating the efficacy of an integrated motivational interviewing and multi-modal exercise intervention for youth with major depression: Healthy Body, Healthy Mind randomised controlled trial protocol
- Creator
- Nasstasia, Yasmina; Baker, Amanda; Halpin, Sean; Hides, Leanne; Lewin, Terry; Kelly, Brian; Callister, Robin
- Date
- 2018
- Type
- Text; Journal article
- Identifier
- http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/182370
- Identifier
- vital:16121
- Identifier
-
https://doi.org/10.1016/j.conctc.2017.11.007
- Identifier
- ISBN:2451-8654 (ISSN)
- Abstract
- Background Recent meta-analytic reviews suggest exercise can reduce depression severity among adults with major depressive disorder (MDD); however, efficacy studies with depressed youth are limited. Few studies have investigated the efficacy of multi-modal exercise interventions in this population, addressed treatment engagement, or explored the differential effects of exercise on depressive symptom profiles. Objectives This paper describes the study protocol and recruitment pattern for an assessor blinded, two-arm randomised controlled trial investigating the efficacy of an integrated motivational interviewing (MI) and multi-modal exercise intervention in youth diagnosed with MDD. Associations between depressive symptom profiles (cognitive, somatic and affective) and psychological, physiological (fitness), and biological (blood biomarker) outcomes will also be examined. Methods Participants aged 15–25 years with current MDD were recruited. Eligible participants were randomised and stratified according to gender and depression severity to either an immediate or delayed (control) group. The immediate group received a brief MI intervention followed by a 12-week small group exercise intervention (3 times per week for 1 h), all delivered by personal trainers. The delayed control group received the same intervention 12-weeks later. Both groups were reassessed at mid-treatment or mid-control, post-treatment or post-control, and follow-up (12 weeks post-treatment). Results 68 participants were recruited and randomly allocated to an intervention group. Conclusion This trial will increase our understanding of the efficacy of multi-modal exercise interventions for depression and the specific effects of exercise on depressive symptom profiles. It also offers a novel contribution by addressing treatment engagement in exercise efficacy trials in youth with MDD. © 2017 The Authors
- Publisher
- Elsevier Inc.
- Relation
- Contemporary Clinical Trials Communications Vol. 9, no. (2018), p. 13-22
- Rights
- All metadata describing materials held in, or linked to, the repository is freely available under a CC0 licence
- Rights
- http://creativecommons.org/licenses/BY-NC-ND/4.0/
- Rights
- Copyright @ 2017 The Authors
- Subject
- 32 Biomedical and Clinical Sciences; 42 Health Sciences; Affective; Cognitive; Depression; Exercise; Motivational interviewing; Youth
- Full Text
- Reviewed
- Funder
- This work was supported by Hunter Medical Research Institute (HMRI) and Beyond Blue. Neither funding body had any role in the collection, analysis, or interpretation of data, or in writing this paper. Both Amanda Baker and Leanne Hides are currently supported by NHMRC ( 1041866, 119098 ) senior research fellowships. Leanne Hides was previously supported by an Australian Research Council Future Fellowship , FT120100780 (2012–2016).
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