- Title
- Commercial lentils (lens culinaris) provide antioxidative and broad-spectrum anti-cancerous effects
- Creator
- Kiran, Sudha; Johnson, Joel; Mani, Janice; Portman, Andrew; Mizzi, Trent; Naiker, Mani
- Date
- 2021
- Type
- Text; Journal article
- Identifier
- http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/176388
- Identifier
- vital:15120
- Identifier
-
https://doi.org/10.18805/lr-557
- Identifier
- ISBN:0250-5371
- Abstract
- Background: Interest is growing surrounding functional foods, which provide health benefits in addition to nutritional value. In particular, there is a focus on pulse crops which contain high levels of polyphenolics, such as lentils. Methods: In this study, polyphenols were extracted from five L. culinaris varieties and characterized by both their antioxidant profile and cytotoxic activity. Result: Hulled varieties had a high content of secondary metabolites (>70 mg GAE/g), while all varieties demonstrated high antioxidant potential (1570-2020 Oxygen Radical Absorbance Capacity index). Furthermore, all extracts showed significant cytotoxicity against H9C2, HepG2, A549 and Calu-1 cancer cell lines. This recommends further investigation into the specific compounds present in L. culinaris, which could potentially be exploited for their anti-cancer activity.
- Relation
- Legume Research Vol. 44, no. 2 (Feb 2021), p. 202-206
- Rights
- All metadata describing materials held in, or linked to, the repository is freely available under a CC0 licence
- Rights
- Copyright © 2019 ARCC Journals
- Subject
- 1103 Clinical Sciences; Antioxidant capacity; ORAC; Polyphenols; Oxidative stress; Inflammation; Growth
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