- Title
- Advancements in electrochemical DNA sensor for detection of human papilloma virus - A review
- Creator
- Rasouli, Elisa; Shahnavaz, Zohreh; Basirun, Wan; Rezayi, Majid; Avan, Amir; Ghayour-Mobarhan, Majid; Khandanlou, Roshanak; Johan, Mohd
- Date
- 2018
- Type
- Text; Journal article; Review
- Identifier
- http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/166102
- Identifier
- vital:13393
- Identifier
-
https://doi.org/10.1016/j.ab.2018.07.002
- Identifier
- ISBN:0003-2697
- Abstract
- Human papillomavirus (HPV) is one of the most common sexually transmitted disease, transmitted through intimate skin contact or mucosal membrane. The HPV virus consists of a double-stranded circular DNA and the role of HPV virus in cervical cancer has been studied extensively. Thus it is critical to develop rapid identification method for early detection of the virus. A portable biosensing device could give rapid and reliable results for the identification and quantitative determination of the virus. The fabrication of electrochemical biosensors is one of the current techniques utilized to achieve this aim. In such electrochemical biosensors, a single-strand DNA is immobilized onto an electrically conducting surface and the changes in electrical parameters due to the hybridization on the electrode surface are measured. This review covers the recent developments in electrochemical DNA biosensors for the detection of HPV virus. Due to the several advantages of electrochemical DNA biosensors, their applications have witnessed an increased interest and research focus nowadays.
- Publisher
- Academic Press Inc.
- Relation
- Analytical Biochemistry Vol. 556, no. (2018), p. 136-144
- Rights
- Crown Copyright © 2018 Published by Elsevier Inc. All rights reserved.
- Rights
- This metadata is freely available under a CCO license
- Subject
- 0301 Analytical Chemistry; 0399 Other Chemical Sciences; 0601 Biochemistry and Cell Biology; Cervical cancer; DNA electrochemical biosensor; Human papilloma virus; Single strand DNA
- Reviewed
- Hits: 2604
- Visitors: 2232
- Downloads: 1
| Thumbnail | File | Description | Size | Format |
|---|