- Title
- Six weeks of conditioning exercise increases total, but not free testosterone in lifelong sedentary aging men
- Creator
- Hayes, Lawrence; Sculthorpe, Nicholas; Herbert, Peter; Baker, Julien; Spagna, Roberto; Grace, Fergal
- Date
- 2015
- Type
- Text; Journal article
- Identifier
- http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/157907
- Identifier
- vital:11710
- Identifier
-
https://doi.org/10.3109/13685538.2015.1046123
- Identifier
- ISSN:1368-5538
- Abstract
- INTRODUCTION: Advancing age is associated with a gradual decline in circulating androgens, and the putative role of exercise training on systemic androgens remains to be adequately defined. METHODS: The present investigation examined the impact of 6 weeks of supervised exercise training on resting levels of systemic hormones in a cohort of lifelong sedentary men [SED (n = 28), 62.5 +/- 5.3 years], compared with a positive control group of age-matched lifelong exercisers [LE (n = 20), 60.4 +/- 4.7 years, >30 years training history]. Blood hormones were sampled pre- and post-intervention from an antecubital forearm vein and analysed using electrochemiluminescent immunoassay. Cardiorespiratory fitness ([Formula: see text]) was determined via indirect calorimetry during an incremental cycle test to volitional exhaustion. RESULTS: Analysis of variance (ANOVA) revealed a lack of significant change in any parameter amongst LE, whilst SED experienced a significant exercise-induced improvement in cardiorespiratory fitness and total testosterone (all p < 0.05). Concurrent increases in sex hormone-binding globulin (SHBG; p < 0.05) resulted in a lack of change to either bioavailable or calculated free testosterone (p > 0.05) amongst SED. CONCLUSIONS: Although resting levels of systemic total testosterone increased in response to 6 weeks of exercise training, increases in SHBG negated any potential relationship between calculated-free or bioavailable testosterone. These findings indicate that increases in bioavailable testosterone fraction are not required for cardiorespiratory fitness improvements in aging men.
- Relation
- Aging Male Vol. 18, no. 3 (2015), p. 195-200
- Rights
- © 2015 Informa UK Ltd.
- Rights
- This metadata is freely available under a CCO license
- Subject
- 1701 Psychology; Aging; Exercise; Sex hormone-binding globulin; Testosterone
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