http://researchonline.federation.edu.au/vital/access/manager/Index ${session.getAttribute("locale")} 5 Safety and immunogenicity of pneumococcal conjugate vaccines in a high-risk population : A randomized controlled trial of 10-valent and 13-valent pneumococcal conjugate vaccine in Papua New Guinean infants http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:14097 75% of children vaccinated with either PCV10 or PCV13. Children carried a total of 65 different pneumococcal serotypes (plus nonserotypeable). At 4 months of age, 92% (95% confidence interval [CI] 85–96) of children vaccinated with PCV10 and 81% (95% CI 72–88) vaccinated with PCV13 were pneumococcal carriers (P = .023), whereas no differences were seen at 9 months of age, or for NTHi carriage. Both vaccines were well tolerated and not associated with serious adverse events. Conclusions. Infant vaccination with 3 doses of PCV10 or PCV13 is safe and immunogenic in a highly endemic setting; however, to significantly reduce pneumococcal disease in these settings, PCVs with broader serotype coverage and potency to reduce pneumococcal carriage are needed. Clinical Trials Registration. NCT01619462.]]> Wed 07 Apr 2021 14:02:11 AEST ]]> Rationale and methods of a randomized controlled trial of immunogenicity, safety and impact on carriage of pneumococcal conjugate and polysaccharide vaccines in infants in Papua New Guinea http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:12936 Wed 07 Apr 2021 14:01:08 AEST ]]> Whole genome sequence analysis of Salmonella Typhi in Papua New Guinea reveals an established population of genotype 2.1.7 sensitive to antimicrobials http://researchonline.federation.edu.au/vital/access/manager/Repository/vital:17442 Thu 23 Mar 2023 11:20:08 AEDT ]]>