Gambling disorder in the UK : key research priorities and the urgent need for independent research funding
- Bowden-Jones, Henrietta, Hook, Roxanne, Grant, Jon, Ioannidis, Konstantinos, Corazza, Ornella, Fineberg, Naomi, Singer, Bryan, Roberts, Amanda, Bethlehem, Richard, Dymond, Simon, Romero-Garcia, Rafa, Robbins, Trevor, Cortese, Samuele, Thomas, Shane, Sahakian, Barbara, Dowling, Nicki, Chamberlain, Samuel
- Authors: Bowden-Jones, Henrietta , Hook, Roxanne , Grant, Jon , Ioannidis, Konstantinos , Corazza, Ornella , Fineberg, Naomi , Singer, Bryan , Roberts, Amanda , Bethlehem, Richard , Dymond, Simon , Romero-Garcia, Rafa , Robbins, Trevor , Cortese, Samuele , Thomas, Shane , Sahakian, Barbara , Dowling, Nicki , Chamberlain, Samuel
- Date: 2022
- Type: Text , Journal article , Review
- Relation: The Lancet Psychiatry Vol. 9, no. 4 (2022), p. 321-329
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- Description: Gambling in the modern era is pervasive owing to the variety of gambling opportunities available, including those that use technology (eg, online applications on smartphones). Although many people gamble recreationally without undue negative effects, a sizeable subset of individuals develop disordered gambling, which is associated with marked functional impairment including other mental health problems, relationship problems, bankruptcy, suicidality, and criminality. The National UK Research Network for Behavioural Addictions (NUK-BA) was established to promote understanding of, research into, and treatments for behavioural addictions including gambling disorder, which is the only formally recognised behavioural addiction. In this Health Policy paper, we outline the status of research and treatment for disordered gambling in the UK (including funding issues) and key research that should be conducted to establish the magnitude of the problem, vulnerability and resilience factors, the underlying neurobiology, long-term consequences, and treatment opportunities. In particular, we emphasise the need to: (1) conduct independent longitudinal research into the prevalence of disordered gambling (including gambling disorder and at-risk gambling), and gambling harms, including in vulnerable and minoritised groups; (2) select and refine the most suitable pragmatic measurement tools; (3) identify predictors (eg, vulnerability and resilience markers) of disordered gambling in people who gamble recreationally, including in vulnerable and minoritised groups; (4) conduct randomised controlled trials on psychological interventions and pharmacotherapy for gambling disorder; (5) improve understanding of the neurobiological basis of gambling disorder, including impulsivity and compulsivity, genetics, and biomarkers; and (6) develop clinical guidelines based on the best contemporary research evidence to guide effective clinical interventions. We also highlight the need to consider what can be learnt from approaches towards mitigating gambling-related harm in other countries. © 2022 Elsevier Ltd
- Authors: Bowden-Jones, Henrietta , Hook, Roxanne , Grant, Jon , Ioannidis, Konstantinos , Corazza, Ornella , Fineberg, Naomi , Singer, Bryan , Roberts, Amanda , Bethlehem, Richard , Dymond, Simon , Romero-Garcia, Rafa , Robbins, Trevor , Cortese, Samuele , Thomas, Shane , Sahakian, Barbara , Dowling, Nicki , Chamberlain, Samuel
- Date: 2022
- Type: Text , Journal article , Review
- Relation: The Lancet Psychiatry Vol. 9, no. 4 (2022), p. 321-329
- Full Text:
- Reviewed:
- Description: Gambling in the modern era is pervasive owing to the variety of gambling opportunities available, including those that use technology (eg, online applications on smartphones). Although many people gamble recreationally without undue negative effects, a sizeable subset of individuals develop disordered gambling, which is associated with marked functional impairment including other mental health problems, relationship problems, bankruptcy, suicidality, and criminality. The National UK Research Network for Behavioural Addictions (NUK-BA) was established to promote understanding of, research into, and treatments for behavioural addictions including gambling disorder, which is the only formally recognised behavioural addiction. In this Health Policy paper, we outline the status of research and treatment for disordered gambling in the UK (including funding issues) and key research that should be conducted to establish the magnitude of the problem, vulnerability and resilience factors, the underlying neurobiology, long-term consequences, and treatment opportunities. In particular, we emphasise the need to: (1) conduct independent longitudinal research into the prevalence of disordered gambling (including gambling disorder and at-risk gambling), and gambling harms, including in vulnerable and minoritised groups; (2) select and refine the most suitable pragmatic measurement tools; (3) identify predictors (eg, vulnerability and resilience markers) of disordered gambling in people who gamble recreationally, including in vulnerable and minoritised groups; (4) conduct randomised controlled trials on psychological interventions and pharmacotherapy for gambling disorder; (5) improve understanding of the neurobiological basis of gambling disorder, including impulsivity and compulsivity, genetics, and biomarkers; and (6) develop clinical guidelines based on the best contemporary research evidence to guide effective clinical interventions. We also highlight the need to consider what can be learnt from approaches towards mitigating gambling-related harm in other countries. © 2022 Elsevier Ltd
- Sinclair, Julia, Aslan, Betul, Agabio, Roberta, Anilkumar, Amith, Brosnan, Mark, Day, Ed, Dowling, Nicki, Flood, Chelsey, Grant, Jon, Halliday, Robyn, Hofvander, Björn, Howes, Leesa, Moseley, Rachel, Myers, Bronwyn, O'Connor, Vincent, Shaya, Gabriel, Thomas, Shane, Robinson, Janine, Chamberlain, Samuel
- Authors: Sinclair, Julia , Aslan, Betul , Agabio, Roberta , Anilkumar, Amith , Brosnan, Mark , Day, Ed , Dowling, Nicki , Flood, Chelsey , Grant, Jon , Halliday, Robyn , Hofvander, Björn , Howes, Leesa , Moseley, Rachel , Myers, Bronwyn , O'Connor, Vincent , Shaya, Gabriel , Thomas, Shane , Robinson, Janine , Chamberlain, Samuel
- Date: 2023
- Type: Text , Journal article
- Relation: Comprehensive Psychiatry Vol. 124, no. (2023), p. 152393-152393
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- Description: Autistic people are more likely to report problematic alcohol and other substance use when compared to the general population. Evidence suggests that up to one in three autistic adults may have an alcohol or other substance use disorder (AUD/SUD), although the evidence base for behavioural addictions is less clear. Autistic people may use substances or engage in potentially addictive behaviours as a means of coping with social anxiety, challenging life problems, or camouflaging in social contexts. Despite the prevalence and detrimental effects of AUD, SUD and behavioural addictions in community samples, literature focusing on the intersection between autism and these conditions is scarce, hindering health policy, research, and clinical practice. We aimed to identify the top 10 priorities to build the evidence for research, policy, and clinical practice at this intersection. A priority-setting partnership was used to address this aim, comprising an international steering committee and stakeholders from various backgrounds, including people with declared lived experience of autism and/or addiction. First, an online survey was used to identify what people considered key questions about Substance use, alcohol use, or behavioural addictions in autistic people (SABA-A). These initial questions were reviewed and amended by stakeholders, and then classified and refined to form the final list of top priorities via an online consensus process. The top ten priorities were identified: three research, three policy, and four practice questions. Future research suggestions are discussed. •Little is known about the overlap between autism and addiction, yet both are common.•This priority-setting partnership identified the top research, policy and clinical practice questions regarding this overlap•Identification of these priorities will assist researchers and experts, and policy makers to address key knowledge gaps.
Transforming global approaches to chronic disease prevention and management across the lifespan : integrating genomics, behavior change, and digital health solutions
- Thomas, Shane, Browning, Collette, Charchar, Fadi, Klein, Britt, Ory, Marcia, Bowden-Jones, Henrietta, Chamberlain, Samuel
- Authors: Thomas, Shane , Browning, Collette , Charchar, Fadi , Klein, Britt , Ory, Marcia , Bowden-Jones, Henrietta , Chamberlain, Samuel
- Date: 2023
- Type: Text , Journal article
- Relation: Frontiers in Public Health Vol. 11, no. (2023), p.
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- Description: Chronic illnesses are a major threat to global population health through the lifespan into older age. Despite world-wide public health goals, there has been a steady increase in chronic and non-communicable diseases (e.g., cancer, cardiovascular and metabolic disorders) and strong growth in mental health disorders. In 2010, 67% of deaths worldwide were due to chronic diseases and this increased to 74% in 2019, with accelerated growth in the COVID-19 era and its aftermath. Aging and wellbeing across the lifespan are positively impacted by the presence of effective prevention and management of chronic illness that can enhance population health. This paper provides a short overview of the journey to this current situation followed by discussion of how we may better address what the World Health Organization has termed the “tsunami of chronic diseases.” In this paper we advocate for the development, validation, and subsequent deployment of integrated: 1. Polygenic and multifactorial risk prediction tools to screen for those at future risk of chronic disease and those with undiagnosed chronic disease. 2. Advanced preventive, behavior change and chronic disease management to maximize population health and wellbeing. 3. Digital health systems to support greater efficiencies in population-scale health prevention and intervention programs. It is argued that each of these actions individually has an emerging evidence base. However, there has been limited research to date concerning the combined population-level health effects of their integration. We outline the conceptual framework within which we are planning and currently conducting studies to investigate the effects of their integration. Copyright © 2023 Thomas, Browning, Charchar, Klein, Ory, Bowden-Jones and Chamberlain.
- Authors: Thomas, Shane , Browning, Collette , Charchar, Fadi , Klein, Britt , Ory, Marcia , Bowden-Jones, Henrietta , Chamberlain, Samuel
- Date: 2023
- Type: Text , Journal article
- Relation: Frontiers in Public Health Vol. 11, no. (2023), p.
- Full Text:
- Reviewed:
- Description: Chronic illnesses are a major threat to global population health through the lifespan into older age. Despite world-wide public health goals, there has been a steady increase in chronic and non-communicable diseases (e.g., cancer, cardiovascular and metabolic disorders) and strong growth in mental health disorders. In 2010, 67% of deaths worldwide were due to chronic diseases and this increased to 74% in 2019, with accelerated growth in the COVID-19 era and its aftermath. Aging and wellbeing across the lifespan are positively impacted by the presence of effective prevention and management of chronic illness that can enhance population health. This paper provides a short overview of the journey to this current situation followed by discussion of how we may better address what the World Health Organization has termed the “tsunami of chronic diseases.” In this paper we advocate for the development, validation, and subsequent deployment of integrated: 1. Polygenic and multifactorial risk prediction tools to screen for those at future risk of chronic disease and those with undiagnosed chronic disease. 2. Advanced preventive, behavior change and chronic disease management to maximize population health and wellbeing. 3. Digital health systems to support greater efficiencies in population-scale health prevention and intervention programs. It is argued that each of these actions individually has an emerging evidence base. However, there has been limited research to date concerning the combined population-level health effects of their integration. We outline the conceptual framework within which we are planning and currently conducting studies to investigate the effects of their integration. Copyright © 2023 Thomas, Browning, Charchar, Klein, Ory, Bowden-Jones and Chamberlain.
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