Association between symptoms and severity of disease in hospitalised novel Coronavirus (COVID-19) patients : a systematic review and meta-analysis
- Talukder, Ashis, Razu, Shaharior, Alif, Sheikh, Rahman, Muhammad Aziz, Islam, Sheikh
- Authors: Talukder, Ashis , Razu, Shaharior , Alif, Sheikh , Rahman, Muhammad Aziz , Islam, Sheikh
- Date: 2022
- Type: Text , Journal article
- Relation: Journal of Multidisciplinary Healthcare Vol. 15, no. (2022), p. 1101-1110
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- Description: Background: Symptoms of the novel coronavirus disease (COVD-19) are well known, although asymptomatic cases were also reported due to this rapidly evolving viral disease. However, there has been limited research with inconsistent findings on symptoms of COVID-19 and disease severity. We aimed to evaluate the association between symptoms and severity of disease in adult patients with confirmed COVID-19 by performing a meta-analysis. Methods: We conducted this study by searching four online databases (Medline, Web of Science, EMBASE and Cochrane library) of published studies that included symptoms of COVID-19 cases and severity of the disease between January 1, 2020, and October 31, 2021. PRISMA and MOOSE guidelines were followed, and only articles published in English were selected. We performed meta-analysis using Mantel-Haenszel random-effects model. Note that we included peer-reviewed studies conducted in Wuhan and published in the English language that reported the clinical characteristics of COVID-19, particularly the symptoms of novel coronavirus patients with their prevalence and distribution of patients based on the severity of the disease. Results: Out of 255 articles identified, a total of twenty articles, including 5390 participants, met the inclusion criteria and were included. Among the participants, 2997 (55.60%) were males, and 974 (18.07%) reported severe conditions. Fever was the most commonly reported symptom in the reported COVID-19 confirmed cases (88.47%, 95% CI: 80.74–93.35%), which was followed by cough, fatigue, and less proportionally dyspnea and myalgia. Dyspnea was the only symptom, which was associated with severity of COVID-19 (OR 2.43, 95% CI: 1.52–3.89). Conclusion: Dyspnoea was found to be associated with severity of COVID-19. People with existing respiratory illnesses, such as chronic obstructive pulmonary diseases need to be careful about the onset of such symptom and should seek medical attention. © 2022 Talukder et al.
- Authors: Talukder, Ashis , Razu, Shaharior , Alif, Sheikh , Rahman, Muhammad Aziz , Islam, Sheikh
- Date: 2022
- Type: Text , Journal article
- Relation: Journal of Multidisciplinary Healthcare Vol. 15, no. (2022), p. 1101-1110
- Full Text:
- Reviewed:
- Description: Background: Symptoms of the novel coronavirus disease (COVD-19) are well known, although asymptomatic cases were also reported due to this rapidly evolving viral disease. However, there has been limited research with inconsistent findings on symptoms of COVID-19 and disease severity. We aimed to evaluate the association between symptoms and severity of disease in adult patients with confirmed COVID-19 by performing a meta-analysis. Methods: We conducted this study by searching four online databases (Medline, Web of Science, EMBASE and Cochrane library) of published studies that included symptoms of COVID-19 cases and severity of the disease between January 1, 2020, and October 31, 2021. PRISMA and MOOSE guidelines were followed, and only articles published in English were selected. We performed meta-analysis using Mantel-Haenszel random-effects model. Note that we included peer-reviewed studies conducted in Wuhan and published in the English language that reported the clinical characteristics of COVID-19, particularly the symptoms of novel coronavirus patients with their prevalence and distribution of patients based on the severity of the disease. Results: Out of 255 articles identified, a total of twenty articles, including 5390 participants, met the inclusion criteria and were included. Among the participants, 2997 (55.60%) were males, and 974 (18.07%) reported severe conditions. Fever was the most commonly reported symptom in the reported COVID-19 confirmed cases (88.47%, 95% CI: 80.74–93.35%), which was followed by cough, fatigue, and less proportionally dyspnea and myalgia. Dyspnea was the only symptom, which was associated with severity of COVID-19 (OR 2.43, 95% CI: 1.52–3.89). Conclusion: Dyspnoea was found to be associated with severity of COVID-19. People with existing respiratory illnesses, such as chronic obstructive pulmonary diseases need to be careful about the onset of such symptom and should seek medical attention. © 2022 Talukder et al.
COVID-19 : factors associated with the psychological distress, fear and resilient coping strategies among community members in Saudi Arabia
- Alharbi, Talal, Alqurashi, Alaa, Mahmud, Ilias, Alharbi, Rayan, Islam, Sheikh, Almustanyir, Sami, Maklad, Ahmed, AlSarraj, Ahmad, Mughaiss, Lujain, Al-Tawfiq, Jaffar, Ahmed, Ahmed, Barry, Mazin, Ghozy, Sherief, Alabdan, Lulwah, Alif, Sheikh, Sultana, Farhana, Salehin, Masudus, Banik, Biswajit, Cross, Wendy, Rahman, Muhammad Aziz
- Authors: Alharbi, Talal , Alqurashi, Alaa , Mahmud, Ilias , Alharbi, Rayan , Islam, Sheikh , Almustanyir, Sami , Maklad, Ahmed , AlSarraj, Ahmad , Mughaiss, Lujain , Al-Tawfiq, Jaffar , Ahmed, Ahmed , Barry, Mazin , Ghozy, Sherief , Alabdan, Lulwah , Alif, Sheikh , Sultana, Farhana , Salehin, Masudus , Banik, Biswajit , Cross, Wendy , Rahman, Muhammad Aziz
- Date: 2023
- Type: Text , Journal article
- Relation: Healthcare (Switzerland) Vol. 11, no. 8 (2023), p.
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- Description: (1) Background: COVID-19 caused the worst international public health crisis, accompanied by major global economic downturns and mass-scale job losses, which impacted the psychosocial wellbeing of the worldwide population, including Saudi Arabia. Evidence of the high-risk groups impacted by the pandemic has been non-existent in Saudi Arabia. Therefore, this study examined factors associated with psychosocial distress, fear of COVID-19 and coping strategies among the general population in Saudi Arabia. (2) Methods: A cross-sectional study was conducted in healthcare and community settings in the Saudi Arabia using an anonymous online questionnaire. The Kessler Psychological Distress Scale (K-10), Fear of COVID-19 Scale (FCV-19S) and Brief Resilient Coping Scale (BRCS) were used to assess psychological distress, fear and coping strategies, respectively. Multivariate logistic regressions were used, and an Adjusted Odds Ratio (AOR) with 95% Confidence Intervals (CIs) was reported. (3) Results: Among 803 participants, 70% (n = 556) were females, and the median age was 27 years; 35% (n = 278) were frontline or essential service workers; and 24% (n = 195) reported comorbid conditions including mental health illness. Of the respondents, 175 (21.8%) and 207 (25.8%) reported high and very high psychological distress, respectively. Factors associated with moderate to high levels of psychological distress were: youth, females, non-Saudi nationals, those experiencing a change in employment or a negative financial impact, having comorbidities, and current smoking. A high level of fear was reported by 89 participants (11.1%), and this was associated with being ex-smokers (3.72, 1.14–12.14, 0.029) and changes in employment (3.42, 1.91–6.11, 0.000). A high resilience was reported by 115 participants (14.3%), and 333 participants (41.5%) had medium resilience. Financial impact and contact with known/suspected cases (1.63, 1.12–2.38, 0.011) were associated with low, medium, to high resilient coping. (4) Conclusions: People in Saudi Arabia were at a higher risk of psychosocial distress along with medium-high resilience during the COVID-19 pandemic, warranting urgent attention from healthcare providers and policymakers to provide specific mental health support strategies for their current wellbeing and to avoid a post-pandemic mental health crisis. © 2023 by the authors.
- Authors: Alharbi, Talal , Alqurashi, Alaa , Mahmud, Ilias , Alharbi, Rayan , Islam, Sheikh , Almustanyir, Sami , Maklad, Ahmed , AlSarraj, Ahmad , Mughaiss, Lujain , Al-Tawfiq, Jaffar , Ahmed, Ahmed , Barry, Mazin , Ghozy, Sherief , Alabdan, Lulwah , Alif, Sheikh , Sultana, Farhana , Salehin, Masudus , Banik, Biswajit , Cross, Wendy , Rahman, Muhammad Aziz
- Date: 2023
- Type: Text , Journal article
- Relation: Healthcare (Switzerland) Vol. 11, no. 8 (2023), p.
- Full Text:
- Reviewed:
- Description: (1) Background: COVID-19 caused the worst international public health crisis, accompanied by major global economic downturns and mass-scale job losses, which impacted the psychosocial wellbeing of the worldwide population, including Saudi Arabia. Evidence of the high-risk groups impacted by the pandemic has been non-existent in Saudi Arabia. Therefore, this study examined factors associated with psychosocial distress, fear of COVID-19 and coping strategies among the general population in Saudi Arabia. (2) Methods: A cross-sectional study was conducted in healthcare and community settings in the Saudi Arabia using an anonymous online questionnaire. The Kessler Psychological Distress Scale (K-10), Fear of COVID-19 Scale (FCV-19S) and Brief Resilient Coping Scale (BRCS) were used to assess psychological distress, fear and coping strategies, respectively. Multivariate logistic regressions were used, and an Adjusted Odds Ratio (AOR) with 95% Confidence Intervals (CIs) was reported. (3) Results: Among 803 participants, 70% (n = 556) were females, and the median age was 27 years; 35% (n = 278) were frontline or essential service workers; and 24% (n = 195) reported comorbid conditions including mental health illness. Of the respondents, 175 (21.8%) and 207 (25.8%) reported high and very high psychological distress, respectively. Factors associated with moderate to high levels of psychological distress were: youth, females, non-Saudi nationals, those experiencing a change in employment or a negative financial impact, having comorbidities, and current smoking. A high level of fear was reported by 89 participants (11.1%), and this was associated with being ex-smokers (3.72, 1.14–12.14, 0.029) and changes in employment (3.42, 1.91–6.11, 0.000). A high resilience was reported by 115 participants (14.3%), and 333 participants (41.5%) had medium resilience. Financial impact and contact with known/suspected cases (1.63, 1.12–2.38, 0.011) were associated with low, medium, to high resilient coping. (4) Conclusions: People in Saudi Arabia were at a higher risk of psychosocial distress along with medium-high resilience during the COVID-19 pandemic, warranting urgent attention from healthcare providers and policymakers to provide specific mental health support strategies for their current wellbeing and to avoid a post-pandemic mental health crisis. © 2023 by the authors.
Ever and cumulative occupational exposure and lung function decline in longitudinal population-based studies : a systematic review and meta-analysis
- Rabbani, Golam, Nimmi, Naima, Benke, Geza, Dharmage, Shyamali, Bui, Dinh, Sim, Malcolm, Abramson, Michael, Alif, Sheikh
- Authors: Rabbani, Golam , Nimmi, Naima , Benke, Geza , Dharmage, Shyamali , Bui, Dinh , Sim, Malcolm , Abramson, Michael , Alif, Sheikh
- Date: 2022
- Type: Text , Journal article , Review
- Relation: Occupational and Environmental Medicine Vol. 80, no. 1 (2022), p. 51-60
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- Description: Objectives Adverse occupational exposures can accelerate age-related lung function decline. Some longitudinal population-based studies have investigated this association. This study aims to examine this association using findings reported by longitudinal population-based studies. Methods Ovid Medline, PubMed, Embase, and Web of Science were searched using keywords and text words related to occupational exposures and lung function and 12 longitudinal population-based studies were identified using predefined inclusion criteria. The quality of the studies was assessed using the Newcastle-Ottawa Scale. Lung function decline was defined as annual loss of forced expiratory volume in 1 s (FEV 1), forced vital capacity (FVC) or the ratio (FEV 1 /FVC). Fixed and random-effects meta-analyses were conducted to calculate pooled estimates for ever and cumulative exposures. Heterogeneity was assessed using the I 2 test, and publication bias was evaluated using funnel plots. Results Ever exposures to gases/fumes, vapours, gases, dusts, fumes (VGDF) and aromatic solvents were significantly associated with FEV 1 decline in meta-analyses. Cumulative exposures for these three occupational agents observed a similar trend of FEV 1 decline. Ever exposures to fungicides and cumulative exposures to biological dust, fungicides and insecticides were associated with FEV 1 decline in fixed-effect models only. No statistically significant association was observed between mineral dust, herbicides and metals and FEV 1 decline in meta-analyses. Conclusion Pooled estimates from the longitudinal population-based studies have provided evidence that occupational exposures are associated with FEV 1 decline. Specific exposure control and respiratory health surveillance are required to protect the lung health of the workers. © 2023 Author(s). Published by BMJ.
- Authors: Rabbani, Golam , Nimmi, Naima , Benke, Geza , Dharmage, Shyamali , Bui, Dinh , Sim, Malcolm , Abramson, Michael , Alif, Sheikh
- Date: 2022
- Type: Text , Journal article , Review
- Relation: Occupational and Environmental Medicine Vol. 80, no. 1 (2022), p. 51-60
- Full Text:
- Reviewed:
- Description: Objectives Adverse occupational exposures can accelerate age-related lung function decline. Some longitudinal population-based studies have investigated this association. This study aims to examine this association using findings reported by longitudinal population-based studies. Methods Ovid Medline, PubMed, Embase, and Web of Science were searched using keywords and text words related to occupational exposures and lung function and 12 longitudinal population-based studies were identified using predefined inclusion criteria. The quality of the studies was assessed using the Newcastle-Ottawa Scale. Lung function decline was defined as annual loss of forced expiratory volume in 1 s (FEV 1), forced vital capacity (FVC) or the ratio (FEV 1 /FVC). Fixed and random-effects meta-analyses were conducted to calculate pooled estimates for ever and cumulative exposures. Heterogeneity was assessed using the I 2 test, and publication bias was evaluated using funnel plots. Results Ever exposures to gases/fumes, vapours, gases, dusts, fumes (VGDF) and aromatic solvents were significantly associated with FEV 1 decline in meta-analyses. Cumulative exposures for these three occupational agents observed a similar trend of FEV 1 decline. Ever exposures to fungicides and cumulative exposures to biological dust, fungicides and insecticides were associated with FEV 1 decline in fixed-effect models only. No statistically significant association was observed between mineral dust, herbicides and metals and FEV 1 decline in meta-analyses. Conclusion Pooled estimates from the longitudinal population-based studies have provided evidence that occupational exposures are associated with FEV 1 decline. Specific exposure control and respiratory health surveillance are required to protect the lung health of the workers. © 2023 Author(s). Published by BMJ.
Exploration of associations between occupational exposures and current adult eczema
- Lopez, Diego, Alif, Sheikh, Dharmage, Shyamali, Lodge, Caroline, Bui, Dinh, Le Moual, Nicole, Waidyatillake, Nilakshi, Su, John, Abramson, Michael, Walters, E., Hamilton, Garun, Bowatte, Gayan, Erbas, Bircan, Benke, Geza, Perret, Jennifer, Lowe, Adrian
- Authors: Lopez, Diego , Alif, Sheikh , Dharmage, Shyamali , Lodge, Caroline , Bui, Dinh , Le Moual, Nicole , Waidyatillake, Nilakshi , Su, John , Abramson, Michael , Walters, E. , Hamilton, Garun , Bowatte, Gayan , Erbas, Bircan , Benke, Geza , Perret, Jennifer , Lowe, Adrian
- Date: 2023
- Type: Text , Journal article
- Relation: Occupational and Environmental Medicine Vol. 80, no. 10 (2023), p. 564-571
- Full Text: false
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- Description: Objectives There is a scarcity of evidence on occupational exposures that may increase eczema in adults. We aimed to investigate potential associations between occupational exposures and eczema in middle-aged adults. Methods A lifetime work history calendar was collected from the Tasmanian Longitudinal Health Study participants when they were at age 53. Their work history was collated with the occupational asthma-specific job exposure matrix to define ever-exposure and cumulative exposure unit-years since no eczema job exposure matrix is available. Eczema was determined using the report of flexural rash that was coming and going for at least 6 months in the last 12 months. Skin prick tests were used to further subgroup eczema and atopic eczema (AE) or non-AE (NAE). Logistic and multinomial regression models were used to investigate the associations. Results Eczema prevalence was 9.1%. Current occupational exposure to animals (adjusted OR, aOR=3.06 (95% CI 1.43 to 6.58)), storage mites (aOR=2.96 (95% CI 1.38 to 6.34)) and endotoxin (aOR=1.95 (95% CI 1.04 to 3.64)) were associated with increased risk of current eczema. Furthermore, increased odds of NAE were associated with current exposure to animals (aOR=5.60 (95% CI 1.45 to 21.7)) and storage mites (aOR=5.63 (95% CI 1.45 to 21.9)). Current exposures to isocyanates (aOR=5.27 (95% CI 1.17 to 23.7)) and acrylates (aOR=8.41 (95% CI 1.60 to 44.3)) were associated with AE. There was no evidence of associations between cumulative exposures and eczema prevalence. Cumulative exposure to metalworking fluids (aOR=1.10 (95% CI 1.01 to 1.22)) was associated with NAE and acrylates (aOR=1.24 (95% CI 1.04 to 1.46)) with AE. Conclusions In this exploratory assessment, multiple occupational exposures were associated with current eczema in middle-aged adults. Raising awareness and limiting these exposures during an individual's productive working life will likely have various health benefits, including reducing eczema prevalence. © Author(s) (or their employer(s)) 2023. No commercial re-use. See rights and permissions. Published by BMJ.
Factors associated with psychological distress, fear and coping strategies during the COVID-19 pandemic in Australia
- Rahman, Muhammad Aziz, Hoque, Nazmul,, Alif, Sheikh, Salehin, Masudus, Islam, Sheikh, Banik, Biswajit, Sharif, Ahmed, Nazim, Nashrin, Sultana, Farhan, Cross, Wendy
- Authors: Rahman, Muhammad Aziz , Hoque, Nazmul, , Alif, Sheikh , Salehin, Masudus , Islam, Sheikh , Banik, Biswajit , Sharif, Ahmed , Nazim, Nashrin , Sultana, Farhan , Cross, Wendy
- Date: 2020
- Type: Text , Journal article
- Relation: Globalization and health Vol. 16, no. 1 (2020), p. 1-15
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- Reviewed:
- Description: The COVID-19 pandemic disrupted the personal, professional and social life of Australians with some people more impacted than others. Objectives This study aimed to identify factors associated with psychological distress, fear and coping strategies during the COVID-19 pandemic in Australia. Methods A cross-sectional online survey was conducted among residents in Australia, including patients, frontline health and other essential service workers, and community members during June 2020. Psychological distress was assessed using the Kessler Psychological Distress Scale (K10) level of fear was assessed using the Fear of COVID-19 Scale (FCV-19S) and coping strategies were assessed using the Brief Resilient Coping Scale (BRCS). Logistic regression was used to identify factors associated with the extent of psychological distress, level of fear and coping strategies while adjusting for potential confounders. Results Among 587 participants, the majority (391, 73.2%)...
- Description: This work was supported by grant 1R21EB022356 from the National Institutes of Health (NIH).
- Authors: Rahman, Muhammad Aziz , Hoque, Nazmul, , Alif, Sheikh , Salehin, Masudus , Islam, Sheikh , Banik, Biswajit , Sharif, Ahmed , Nazim, Nashrin , Sultana, Farhan , Cross, Wendy
- Date: 2020
- Type: Text , Journal article
- Relation: Globalization and health Vol. 16, no. 1 (2020), p. 1-15
- Full Text:
- Reviewed:
- Description: The COVID-19 pandemic disrupted the personal, professional and social life of Australians with some people more impacted than others. Objectives This study aimed to identify factors associated with psychological distress, fear and coping strategies during the COVID-19 pandemic in Australia. Methods A cross-sectional online survey was conducted among residents in Australia, including patients, frontline health and other essential service workers, and community members during June 2020. Psychological distress was assessed using the Kessler Psychological Distress Scale (K10) level of fear was assessed using the Fear of COVID-19 Scale (FCV-19S) and coping strategies were assessed using the Brief Resilient Coping Scale (BRCS). Logistic regression was used to identify factors associated with the extent of psychological distress, level of fear and coping strategies while adjusting for potential confounders. Results Among 587 participants, the majority (391, 73.2%)...
- Description: This work was supported by grant 1R21EB022356 from the National Institutes of Health (NIH).
Global, regional, and national incidence of six major immune-mediated inflammatory diseases: findings from the global burden of disease study 2019
- Wu, Dongze, Jin, Yingzhao, Xing, Yuhan, Abate, Melsew, Abbasian, Mohammadreza, Abbasi-Kangevari, Mohsen, Abbasi-Kangevari, Zeinab, Abd-Allah, Foad, Abdelmasseh, Michael, Abdollahifar, Mohammad-Amin, Abdulah, Deldar, Abedi, Aidin, Abedi, Vida, Abidi, Hassan, Aboagye, Richard, Abolhassani, Hassan, Abuabara, Katrina, Abyadeh, Morteza, Addo, Isaac, Adeniji, Kayode, Adepoju, Abiola, Adesina, Miracle, Adnani, Qorinah, Afarideh, Mohsen, Aghamiri, Shahin, Agodi, Antonella, Agrawal, Anurag, Arriagada, Constanza, Ahmad, Antonella, Rahman, Muhammad Aziz, Alif, Sheikh
- Authors: Wu, Dongze , Jin, Yingzhao , Xing, Yuhan , Abate, Melsew , Abbasian, Mohammadreza , Abbasi-Kangevari, Mohsen , Abbasi-Kangevari, Zeinab , Abd-Allah, Foad , Abdelmasseh, Michael , Abdollahifar, Mohammad-Amin , Abdulah, Deldar , Abedi, Aidin , Abedi, Vida , Abidi, Hassan , Aboagye, Richard , Abolhassani, Hassan , Abuabara, Katrina , Abyadeh, Morteza , Addo, Isaac , Adeniji, Kayode , Adepoju, Abiola , Adesina, Miracle , Adnani, Qorinah , Afarideh, Mohsen , Aghamiri, Shahin , Agodi, Antonella , Agrawal, Anurag , Arriagada, Constanza , Ahmad, Antonella , Rahman, Muhammad Aziz , Alif, Sheikh
- Date: 2023
- Type: Text , Journal article
- Relation: eClinicalMedicine Vol. 64, no. (2023), p.
- Full Text:
- Reviewed:
- Description: Background: The causes for immune-mediated inflammatory diseases (IMIDs) are diverse and the incidence trends of IMIDs from specific causes are rarely studied. The study aims to investigate the pattern and trend of IMIDs from 1990 to 2019. Methods: We collected detailed information on six major causes of IMIDs, including asthma, inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis, psoriasis, and atopic dermatitis, between 1990 and 2019, derived from the Global Burden of Disease study in 2019. The average annual percent change (AAPC) in number of incidents and age standardized incidence rate (ASR) on IMIDs, by sex, age, region, and causes, were calculated to quantify the temporal trends. Findings: In 2019, rheumatoid arthritis, atopic dermatitis, asthma, multiple sclerosis, psoriasis, inflammatory bowel disease accounted 1.59%, 36.17%, 54.71%, 0.09%, 6.84%, 0.60% of overall new IMIDs cases, respectively. The ASR of IMIDs showed substantial regional and global variation with the highest in High SDI region, High-income North America, and United States of America. Throughout human lifespan, the age distribution of incident cases from six IMIDs was quite different. Globally, incident cases of IMIDs increased with an AAPC of 0.68 and the ASR decreased with an AAPC of
- Authors: Wu, Dongze , Jin, Yingzhao , Xing, Yuhan , Abate, Melsew , Abbasian, Mohammadreza , Abbasi-Kangevari, Mohsen , Abbasi-Kangevari, Zeinab , Abd-Allah, Foad , Abdelmasseh, Michael , Abdollahifar, Mohammad-Amin , Abdulah, Deldar , Abedi, Aidin , Abedi, Vida , Abidi, Hassan , Aboagye, Richard , Abolhassani, Hassan , Abuabara, Katrina , Abyadeh, Morteza , Addo, Isaac , Adeniji, Kayode , Adepoju, Abiola , Adesina, Miracle , Adnani, Qorinah , Afarideh, Mohsen , Aghamiri, Shahin , Agodi, Antonella , Agrawal, Anurag , Arriagada, Constanza , Ahmad, Antonella , Rahman, Muhammad Aziz , Alif, Sheikh
- Date: 2023
- Type: Text , Journal article
- Relation: eClinicalMedicine Vol. 64, no. (2023), p.
- Full Text:
- Reviewed:
- Description: Background: The causes for immune-mediated inflammatory diseases (IMIDs) are diverse and the incidence trends of IMIDs from specific causes are rarely studied. The study aims to investigate the pattern and trend of IMIDs from 1990 to 2019. Methods: We collected detailed information on six major causes of IMIDs, including asthma, inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis, psoriasis, and atopic dermatitis, between 1990 and 2019, derived from the Global Burden of Disease study in 2019. The average annual percent change (AAPC) in number of incidents and age standardized incidence rate (ASR) on IMIDs, by sex, age, region, and causes, were calculated to quantify the temporal trends. Findings: In 2019, rheumatoid arthritis, atopic dermatitis, asthma, multiple sclerosis, psoriasis, inflammatory bowel disease accounted 1.59%, 36.17%, 54.71%, 0.09%, 6.84%, 0.60% of overall new IMIDs cases, respectively. The ASR of IMIDs showed substantial regional and global variation with the highest in High SDI region, High-income North America, and United States of America. Throughout human lifespan, the age distribution of incident cases from six IMIDs was quite different. Globally, incident cases of IMIDs increased with an AAPC of 0.68 and the ASR decreased with an AAPC of
Long-term occupational exposures on disability-free survival and mortality in older adults
- Alif, Sheikh, Benke, Geza, Kromhout, Hans, Vermeulen, Roel, Tran, Cammie, Ronaldson, Kathlyn, Walker-Bone, Karen, Woods, Robyn, Beilin, Lawerence, Tonkin, Andrew, Owen, Alice, McNeil, John
- Authors: Alif, Sheikh , Benke, Geza , Kromhout, Hans , Vermeulen, Roel , Tran, Cammie , Ronaldson, Kathlyn , Walker-Bone, Karen , Woods, Robyn , Beilin, Lawerence , Tonkin, Andrew , Owen, Alice , McNeil, John
- Date: 2023
- Type: Text , Journal article
- Relation: Occupational Medicine Vol. 73, no. 8 (2023), p. 492-499
- Full Text:
- Reviewed:
- Description: Background The impact of long-term occupational exposures on health in older adults is increasingly relevant as populations age. To date, no studies have reported their impact on survival free of disability in older adults. Aims We aimed to investigate the association between long-term occupational exposure and disability-free survival (DFS), all-cause mortality and cause-specific mortality in initially healthy older adults. Methods We analysed data from 12 215 healthy participants in the ASPirin in Reducing Events in the Elderly (ASPREE) study whose mean age was 75 years. Their work history was collated with the ‘ALOHA-plus JEM’ (Job Exposure Matrix) to assign occupational exposures. The primary endpoint, DFS, was a composite measure of death, dementia or persistent physical disability. The secondary endpoint, mortality, was classified according to the underlying cause. Cox proportional hazard models were used to calculate hazard ratios and 95% confidence intervals, adjusted for confounders. Results A total of 1835 individuals reached the DFS endpoint during the median 4.7 years follow-up period. Both ever-high and cumulative exposure to all dusts and all pesticides during a person’s working years were associated with reduced DFS. Compared to no exposure, men with high exposure to dusts and pesticides had a reduced DFS. Neither of these exposures were significantly associated with all-cause mortality. Men with high occupational exposure to solvents and women exposed to dusts experienced higher all-cause and cancer-related mortality. Conclusions Long-term occupational exposure to all dusts and pesticides was associated with a reduced DFS and increased mortality in community-dwelling healthy older adults. © The Author(s) 2023. Published by Oxford University Press on behalf of the Society of Occupational Medicine.
- Authors: Alif, Sheikh , Benke, Geza , Kromhout, Hans , Vermeulen, Roel , Tran, Cammie , Ronaldson, Kathlyn , Walker-Bone, Karen , Woods, Robyn , Beilin, Lawerence , Tonkin, Andrew , Owen, Alice , McNeil, John
- Date: 2023
- Type: Text , Journal article
- Relation: Occupational Medicine Vol. 73, no. 8 (2023), p. 492-499
- Full Text:
- Reviewed:
- Description: Background The impact of long-term occupational exposures on health in older adults is increasingly relevant as populations age. To date, no studies have reported their impact on survival free of disability in older adults. Aims We aimed to investigate the association between long-term occupational exposure and disability-free survival (DFS), all-cause mortality and cause-specific mortality in initially healthy older adults. Methods We analysed data from 12 215 healthy participants in the ASPirin in Reducing Events in the Elderly (ASPREE) study whose mean age was 75 years. Their work history was collated with the ‘ALOHA-plus JEM’ (Job Exposure Matrix) to assign occupational exposures. The primary endpoint, DFS, was a composite measure of death, dementia or persistent physical disability. The secondary endpoint, mortality, was classified according to the underlying cause. Cox proportional hazard models were used to calculate hazard ratios and 95% confidence intervals, adjusted for confounders. Results A total of 1835 individuals reached the DFS endpoint during the median 4.7 years follow-up period. Both ever-high and cumulative exposure to all dusts and all pesticides during a person’s working years were associated with reduced DFS. Compared to no exposure, men with high exposure to dusts and pesticides had a reduced DFS. Neither of these exposures were significantly associated with all-cause mortality. Men with high occupational exposure to solvents and women exposed to dusts experienced higher all-cause and cancer-related mortality. Conclusions Long-term occupational exposure to all dusts and pesticides was associated with a reduced DFS and increased mortality in community-dwelling healthy older adults. © The Author(s) 2023. Published by Oxford University Press on behalf of the Society of Occupational Medicine.
Occupational characteristics and disability-free survival after retirement age : an exploratory analysis from the ASPREE study
- Alif, Sheikh, Benke, Geza, Ronaldson, Kathlyn, Walker-Bone, Karen, Woods, Robyn, Tran, Cammie, Beilin, Lawrence, Tonkin, Andrew, Owen, Alice, McNeil, John
- Authors: Alif, Sheikh , Benke, Geza , Ronaldson, Kathlyn , Walker-Bone, Karen , Woods, Robyn , Tran, Cammie , Beilin, Lawrence , Tonkin, Andrew , Owen, Alice , McNeil, John
- Date: 2023
- Type: Text , Journal article
- Relation: Frontiers in Public Health Vol. 11, no. (2023), p.
- Full Text:
- Reviewed:
- Description: Background: Certain occupational characteristics have been linked with poor health and reduced longevity. However, the association between occupational characteristics and survival free of disability in a post-retirement age group has not been investigated. Methods: We investigated outcomes in 12,215 healthy older Australian adults in the Aspirin in Reducing Events in the Elderly (ASPREE) and ASPREE Longitudinal Study of Older Persons (ALSOP) sub-study. The ISCO-88 major occupational groups, settings, and activity levels were assigned based on free-text job descriptions. The Finnish Job Exposure Matrix was used to assign occupational characteristics to the three longest-held jobs. The primary endpoint, disability-free survival, was defined as a composite measure of death, dementia, or persistent physical disability. The endpoint of all-cause mortality was analyzed separately. Because of multiple exploratory analyses, only those associations with a two-sided value of p less than 0.005 were considered statistically significant. Cox proportional hazard models were used to calculate adjusted hazard ratios. Results: Having worked in an ‘elementary’ occupation was associated with a reduction in disability-free survival. A specific impact on disability-free survival was observed among those whose work had involved high accident risk and adverse social climate. No significant relationship was identified with those previously exposed to sedentary work, vigorous physical activity, work primarily outdoors, or a range of other occupational characteristics. All-cause mortality was not increased among any of the occupational groups. Conclusion: This exploratory study found a reduction in disability-free survival among people who worked in ‘elementary’ occupations, with specific risks associated with occupations involving high accident risks and adverse social climate. Copyright © 2023 Alif, Benke, Ronaldson, Walker-Bone, Woods, Tran, Beilin, Tonkin, Owen and McNeil.
- Authors: Alif, Sheikh , Benke, Geza , Ronaldson, Kathlyn , Walker-Bone, Karen , Woods, Robyn , Tran, Cammie , Beilin, Lawrence , Tonkin, Andrew , Owen, Alice , McNeil, John
- Date: 2023
- Type: Text , Journal article
- Relation: Frontiers in Public Health Vol. 11, no. (2023), p.
- Full Text:
- Reviewed:
- Description: Background: Certain occupational characteristics have been linked with poor health and reduced longevity. However, the association between occupational characteristics and survival free of disability in a post-retirement age group has not been investigated. Methods: We investigated outcomes in 12,215 healthy older Australian adults in the Aspirin in Reducing Events in the Elderly (ASPREE) and ASPREE Longitudinal Study of Older Persons (ALSOP) sub-study. The ISCO-88 major occupational groups, settings, and activity levels were assigned based on free-text job descriptions. The Finnish Job Exposure Matrix was used to assign occupational characteristics to the three longest-held jobs. The primary endpoint, disability-free survival, was defined as a composite measure of death, dementia, or persistent physical disability. The endpoint of all-cause mortality was analyzed separately. Because of multiple exploratory analyses, only those associations with a two-sided value of p less than 0.005 were considered statistically significant. Cox proportional hazard models were used to calculate adjusted hazard ratios. Results: Having worked in an ‘elementary’ occupation was associated with a reduction in disability-free survival. A specific impact on disability-free survival was observed among those whose work had involved high accident risk and adverse social climate. No significant relationship was identified with those previously exposed to sedentary work, vigorous physical activity, work primarily outdoors, or a range of other occupational characteristics. All-cause mortality was not increased among any of the occupational groups. Conclusion: This exploratory study found a reduction in disability-free survival among people who worked in ‘elementary’ occupations, with specific risks associated with occupations involving high accident risks and adverse social climate. Copyright © 2023 Alif, Benke, Ronaldson, Walker-Bone, Woods, Tran, Beilin, Tonkin, Owen and McNeil.
Psychological distress, fear and coping strategies during the second and third waves of the COVID-19 pandemic in Southern Germany
- Elsayed, Mohamed, Schönfeldt-Lecuona, Carlos, Welte, Xenia, Dardeer, Khaled, Kamal, Manar, Abdelnaby, Ramy, Rudek, Markus, Riedel, Evelyne, Denkinger, Michael, Gahr, Maximilian, Connemann, Bernhard, Alif, Sheikh, Banik, Biswajit, Cross, Wendy, Rahman, Muhammad Aziz
- Authors: Elsayed, Mohamed , Schönfeldt-Lecuona, Carlos , Welte, Xenia , Dardeer, Khaled , Kamal, Manar , Abdelnaby, Ramy , Rudek, Markus , Riedel, Evelyne , Denkinger, Michael , Gahr, Maximilian , Connemann, Bernhard , Alif, Sheikh , Banik, Biswajit , Cross, Wendy , Rahman, Muhammad Aziz
- Date: 2022
- Type: Text , Journal article
- Relation: Frontiers in Psychiatry Vol. 13, no. (2022), p.
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- Description: Background: The COVID-19 pandemic has imposed enormous psychological discomfort and fear across the globe, including Germany. Objectives: To assess the levels of COVID-19 associated psychological distress and fear amongst Southern German population, and to identify their coping strategies. Methods: A cross-sectional survey using an online questionnaire was conducted in healthcare and community settings in the region of Ulm, Southern Germany. Assessment inventories were the Kessler Psychological Distress Scale (K-10), the Brief Resilient Coping Scale (BRCS), and the Fear of COVID-19 Scale (FCV-19S), which were valid and reliable tools. Results: A total of 474 Individuals participated in the study. The mean age was 33.6 years, and 327 (69%) were females. Most participants (n = 381, 80.4%) had high levels of psychological distress, whereas only 5.1% had high levels of fear, and two-thirds of participants showed higher levels of coping. Moderate to very high levels of psychological distress were associated with being female, living alone, distress due to employment changes, experiencing financial impact, having multiple co-morbidities, being a smoker, increased alcohol use over the previous 6 months, contact with COVID-19 cases and healthcare providers for COVID-19-related stress. Individuals who were
- Authors: Elsayed, Mohamed , Schönfeldt-Lecuona, Carlos , Welte, Xenia , Dardeer, Khaled , Kamal, Manar , Abdelnaby, Ramy , Rudek, Markus , Riedel, Evelyne , Denkinger, Michael , Gahr, Maximilian , Connemann, Bernhard , Alif, Sheikh , Banik, Biswajit , Cross, Wendy , Rahman, Muhammad Aziz
- Date: 2022
- Type: Text , Journal article
- Relation: Frontiers in Psychiatry Vol. 13, no. (2022), p.
- Full Text:
- Reviewed:
- Description: Background: The COVID-19 pandemic has imposed enormous psychological discomfort and fear across the globe, including Germany. Objectives: To assess the levels of COVID-19 associated psychological distress and fear amongst Southern German population, and to identify their coping strategies. Methods: A cross-sectional survey using an online questionnaire was conducted in healthcare and community settings in the region of Ulm, Southern Germany. Assessment inventories were the Kessler Psychological Distress Scale (K-10), the Brief Resilient Coping Scale (BRCS), and the Fear of COVID-19 Scale (FCV-19S), which were valid and reliable tools. Results: A total of 474 Individuals participated in the study. The mean age was 33.6 years, and 327 (69%) were females. Most participants (n = 381, 80.4%) had high levels of psychological distress, whereas only 5.1% had high levels of fear, and two-thirds of participants showed higher levels of coping. Moderate to very high levels of psychological distress were associated with being female, living alone, distress due to employment changes, experiencing financial impact, having multiple co-morbidities, being a smoker, increased alcohol use over the previous 6 months, contact with COVID-19 cases and healthcare providers for COVID-19-related stress. Individuals who were
Psychological impact of COVID-19 on healthcare workers : cross-sectional analyses from 14 countries
- Ghozy, Sherief, Cross, Wendy, Islam, Shariful, Al-Mawali, Adhra Hilal, AlQurashi, Alaa Ashraf, Hamza, Amr, Joseph, Bindu, Banik, Biswajit, Elsori, Deena H., Sultana, Farhana, Yasmin, Farhana, Mahmud, Ilias, Lam, Louisa, Hammoud, Majeda, Salehin, Masudus, Keblawi, Mohammed Ali, Eltewacy, Nael Kamel, Al Laham, Nahed, El-Khazragy, Nashwa, Oli, Natalia, Tungpunkom, Patraporn, Almustanyir, Sami, Chair, Sek, Alif, Sheikh, Al-Madhoun, Sondos, Chien, Wai Tong, Rahman, Muhammad Aziz
- Authors: Ghozy, Sherief , Cross, Wendy , Islam, Shariful , Al-Mawali, Adhra Hilal , AlQurashi, Alaa Ashraf , Hamza, Amr , Joseph, Bindu , Banik, Biswajit , Elsori, Deena H. , Sultana, Farhana , Yasmin, Farhana , Mahmud, Ilias , Lam, Louisa , Hammoud, Majeda , Salehin, Masudus , Keblawi, Mohammed Ali , Eltewacy, Nael Kamel , Al Laham, Nahed , El-Khazragy, Nashwa , Oli, Natalia , Tungpunkom, Patraporn , Almustanyir, Sami , Chair, Sek , Alif, Sheikh , Al-Madhoun, Sondos , Chien, Wai Tong , Rahman, Muhammad Aziz
- Date: 2022
- Type: Text , Journal article
- Relation: Glob. Ment. Health Vol. 9, no. (2022), p. 328-338
- Full Text:
- Reviewed:
- Description: Healthcare workers (HCWs) have been impacted psychologically due to their professional responsibilities over the prolonged era of the coronavirus disease 2019 (COVID-19) pandemic. The study aimed to identify the predictors of psychological distress, fear, and coping during the COVID-19 pandemic among HCWs. A cross-sectional online survey was conducted among self-identified HCWs across 14 countries (12 from Asia and two from Africa). The Kessler Psychological Distress Scale, the Fear of COVID-19 Scale, and the Brief Resilient Coping Scale were used to assess the psychological distress, fear, and coping of HCWs, respectively. A total of 2447 HCWs participated 36% were doctors, and 42% were nurses, with a mean age of 36 (±12) years, and 70% were females. Moderate to very-high psychological distress was prevalent in 67% of the HCWs the lowest rate was reported in the United Arab Emirates (1%) and the highest in Indonesia (16%). The prevalence of high levels of fear was 20% the lowest rate was reported in Libya (9%) and the highest in Egypt (32%). The prevalence of medium-to-high resilient coping was 63% the lowest rate was reported in Libya (28%) and the highest in Syria (76%). COVID-19 has augmented the psychological distress among HCWs. Factors identified in this study should be considered in managing the wellbeing of HCWs, who had been serving as the frontline drivers in managing the crisis successfully across all participating countries. Furthermore, interventions to address their psychological distress should be considered.
- Authors: Ghozy, Sherief , Cross, Wendy , Islam, Shariful , Al-Mawali, Adhra Hilal , AlQurashi, Alaa Ashraf , Hamza, Amr , Joseph, Bindu , Banik, Biswajit , Elsori, Deena H. , Sultana, Farhana , Yasmin, Farhana , Mahmud, Ilias , Lam, Louisa , Hammoud, Majeda , Salehin, Masudus , Keblawi, Mohammed Ali , Eltewacy, Nael Kamel , Al Laham, Nahed , El-Khazragy, Nashwa , Oli, Natalia , Tungpunkom, Patraporn , Almustanyir, Sami , Chair, Sek , Alif, Sheikh , Al-Madhoun, Sondos , Chien, Wai Tong , Rahman, Muhammad Aziz
- Date: 2022
- Type: Text , Journal article
- Relation: Glob. Ment. Health Vol. 9, no. (2022), p. 328-338
- Full Text:
- Reviewed:
- Description: Healthcare workers (HCWs) have been impacted psychologically due to their professional responsibilities over the prolonged era of the coronavirus disease 2019 (COVID-19) pandemic. The study aimed to identify the predictors of psychological distress, fear, and coping during the COVID-19 pandemic among HCWs. A cross-sectional online survey was conducted among self-identified HCWs across 14 countries (12 from Asia and two from Africa). The Kessler Psychological Distress Scale, the Fear of COVID-19 Scale, and the Brief Resilient Coping Scale were used to assess the psychological distress, fear, and coping of HCWs, respectively. A total of 2447 HCWs participated 36% were doctors, and 42% were nurses, with a mean age of 36 (±12) years, and 70% were females. Moderate to very-high psychological distress was prevalent in 67% of the HCWs the lowest rate was reported in the United Arab Emirates (1%) and the highest in Indonesia (16%). The prevalence of high levels of fear was 20% the lowest rate was reported in Libya (9%) and the highest in Egypt (32%). The prevalence of medium-to-high resilient coping was 63% the lowest rate was reported in Libya (28%) and the highest in Syria (76%). COVID-19 has augmented the psychological distress among HCWs. Factors identified in this study should be considered in managing the wellbeing of HCWs, who had been serving as the frontline drivers in managing the crisis successfully across all participating countries. Furthermore, interventions to address their psychological distress should be considered.
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