Improving risk grouping rules for prostate cancer patients with optimization
- Authors: Churilov, Leonid , Bagirov, Adil , Schwartz, Daniel , Smith, Kate , Dally, Michael
- Date: 2004
- Type: Text , Conference paper
- Relation: Paper presented at the 37th Annual Hawaii International Conference on System Sciences, Big Island, Hawaii : 5th January, 2004
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- Description: Data mining techniques provide a popular and powerful toolset to address both clinical and management issues in the area of health care. This paper describes the study of assigning prostate cancer patients into homogenous groups with the aim to support future clinical treatment decisions. The cluster analysis based model is suggested and an application of non-smooth non-convex optimization techniques to solve this model is discussed. It is demonstrated that using the optimization based approach to data mining of a prostate cancer patients database can lead to generation of a significant amount of new knowledge that can be effectively utilized to enhance clinical decision making.
- Description: E1
- Description: 2003000846
Data mining with combined use of optimization techniques and self-organizing maps for improving risk grouping rules : Application to prostate cancer patients
- Authors: Churilov, Leonid , Bagirov, Adil , Schwartz, Daniel , Smith, Kate , Dally, Michael
- Date: 2005
- Type: Text , Journal article
- Relation: Journal of Management Information Systems Vol. 21, no. 4 (2005), p. 85-100
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- Description: Data mining techniques provide a popular and powerful tool set to generate various data-driven classification systems. In this paper, we investigate the combined use of self-organizing maps (SOM) and nonsmooth nonconvex optimization techniques in order to produce a working case of a data-driven risk classification system. The optimization approach strengthens the validity of SOM results, and the improved classification system increases both the quality of prediction and the homogeneity within the risk groups. Accurate classification of prostate cancer patients into risk groups is important to assist in the identification of appropriate treatment paths. We start with the existing rules and aim to improve classification accuracy by identifying inconsistencies utilizing self-organizing maps as a data visualization tool. Then, we progress to the study of assigning prostate cancer patients into homogenous groups with the aim to support future clinical treatment decisions. Using the case of prostate cancer patients grouping, we demonstrate strong potential of data-driven risk classification schemes for addressing the risk grouping issues in more general organizational settings. © 2005 M.E. Sharpe, Inc.
- Description: C1
- Description: 2003001265