Clinical and Cost-Effectiveness of Therapist-Guided Internet-Delivered Cognitive Behavior Therapy for Older Adults With Symptoms of Anxiety: A Randomized Controlled Trial
- Authors: Dear, Blake , Zou, Judy , Ali, Shehzad , Lorian, Carolyn , Johnston, Luke , Sheehan, Joanne , Staples, Lauren , Gandy, Milena , Fogliati, Vincent , Klein, Britt , Titov, Nickolai
- Date: 2015
- Type: Text , Journal article
- Relation: Behavior Therapy Vol. 46, no. 2 (2015), p. 206-217
- Full Text: false
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- Description: There is preliminary support for internet-delivered cognitive behaviour therapy (iCBT) as a way of improving access to treatment among older adults with anxiety. The aim of this randomized controlled trial (RCT) was to examine the efficacy, long-term outcomes, and cost-effectiveness of an iCBT program for adults over 60. years of age with anxiety. Successful applicants were randomly allocated to either the treatment group (n= 35) or the waitlist control group (n= 37). The online treatment course was delivered over 8. weeks and provided with brief weekly contact with a clinical psychologist via telephone or secure email. Eighty-four percent of participants completed the iCBT course within the 8. weeks and 90% provided data at posttreatment. Significantly lower scores on measures of anxiety (Cohen's d=. 1.43; 95% CI: 0.89 - 1.93) and depression (Cohen's d=. 1.79; 95% CI: 1.21 - 2.32) were found among the treatment group compared to the control group at posttreatment. These lower scores were maintained at 3-month and 12-month follow-up and the treatment group rated the iCBT treatment as acceptable. The treatment group had slightly higher costs ($92.2; 95% CI: $38.7 to $149.2) and Quality-Adjusted Life-Years (QALYs. =. 0.010; 95% CI: 0.003 to 0.018) than the control group at posttreatment and the intervention was found to have a greater than 95% probability of being cost-effective. The results support iCBT as an efficacious and cost-effective treatment option for older adults with symptoms of anxiety. © 2014 Association for Behavioral and Cognitive Therapies.
Examining self-guided internet-delivered cognitive behavior therapy for older adults with symptoms of anxiety and depression: Two feasibility open trials
- Authors: Dear, Blake , Zou, Judy , Ali, Shehzad , Lorian, Carolyn , Johnston, Luke , Terides, Matthew , Staples, Lauren , Gandy, Milena , Fogliati, Vincent , Klein, Britt , Titov, Nickolai
- Date: 2015
- Type: Text , Journal article
- Relation: Internet Interventions Vol. 2, no. (2015), p. 17-23
- Full Text: false
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- Description: Self-guided internet-delivered cognitive behavior therapy (iCBT) has considerable public health potential for treating anxiety and depression. However, no research has examined the use of self-guided iCBT, that is, treatment without contact with a clinician, specifically for older adults. The aim of the present study was to undertake a preliminary examination of the acceptability, efficacy and health economic impact of two entirely self-guided iCBT programs for adults over 60. years of age with anxiety and depression. Two separate single-group feasibility open trials of self-guided iCBT were conducted, the Anxiety Trial (n. =. 27) and the Depression Trial (n. =. 20), using the control groups of two randomized controlled trials. The online treatment packages consisted of five online educational lessons, which were delivered over 8. weeks without clinical contact. Participants rated the interventions as acceptable with more than 90% reporting the course was worth their time and more than 70% of participants completing at least 3 of the 5 lessons within the eight weeks. Significant reductions on measures of anxiety (Generalized Anxiety Disorder 7-item; GAD-7) and depression (Patient Health Questionnaire 9-item; PHQ-9) were observed from pre-treatment to post-treatment in both the Anxiety Trial (GAD-7 Cohen's d=. 1.17; 95% CI: 0.55 to 1.75) and the Depression Trial (PHQ-9 Cohen's d=. 1.06; 95% CI: 0.33 to 1.73). The economic analyses indicated that there was statistically significant improvement in health-related quality of life compared to baseline and marginally higher costs associated with treatment for both the Anxiety Trial ($69.84; 95% CI: $4.24 to $135.45) and the Depression Trial ($54.98; 95% CI: $3.84 to $106.12). The results provide preliminary support for the potential of entirely self-guided iCBT for older adults with anxiety and depression and indicate larger scale and controlled research trials are warranted.
Clinical and Cost-Effectiveness of Therapist-Guided Internet-Delivered Cognitive Behavior Therapy for Older Adults With Symptoms of Depression: A Randomized Controlled Trial
- Authors: Titov, Nickolai , Dear, Blake , Ali, Shehzad , Zou, Judy , Lorian, Carolyn , Johnston, Luke , Terides, Matthew , Kayrouz, Rony , Klein, Britt , Gandy, Milena , Fogliati, Vincent
- Date: 2015
- Type: Text , Journal article
- Relation: Behavior Therapy Vol. 46, no. 2 (2015), p. 193-205
- Full Text: false
- Reviewed:
- Description: Depression is a common and significant health problem among older adults. Unfortunately, while effective psychological treatments exist, few older adults access treatment. The aim of the present randomized controlled trial (RCT) was to examine the efficacy, long-term outcomes, and cost-effectiveness of a therapist-guided internet-delivered cognitive behavior therapy (iCBT) intervention for Australian adults over 60. years of age with symptoms of depression. Participants were randomly allocated to either a treatment group (n= 29) or a delayed-treatment waitlist control group (n=. 25). Twenty-seven treatment group participants started the iCBT treatment and 70% completed the treatment within the 8-week course, with 85% of participants providing data at posttreatment. Treatment comprised an online 5-lesson iCBT course with brief weekly contact with a clinical psychologist, delivered over 8. weeks. The primary outcome measure was the Patient Health Questionnaire-9 Item (PHQ-9), a measure of symptoms and severity of depression. Significantly lower scores on the PHQ-9 (Cohen's d=. 2.08; 95% CI: 1.38 - 2.72) and on a measure of anxiety (Generalized Anxiety Disorder-7 Item) (Cohen's d=. 1.22; 95% CI: 0.61 - 1.79) were observed in the treatment group compared to the control group at posttreatment. The treatment group maintained these lower scores at the 3-month and 12-month follow-up time points and the iCBT treatment was rated as acceptable by participants. The treatment group had slightly higher Quality-Adjusted Life-Years (QALYs) than the control group at posttreatment (estimate: 0.012; 95% CI: 0.004 to 0.020) and, while being a higher cost (estimate $52.9. l 95% CI: -. 23.8 to 128.2), the intervention was cost-effective according to commonly used willingness-to-pay thresholds in Australia. The results support the potential efficacy and cost-effectiveness of therapist-guided iCBT as a treatment for older adults with symptoms of depression. © 2014 Association for Behavioral and Cognitive Therapies.
MindSpot Clinic : An accessible, efficient, and effective online treatment service for anxiety and depression
- Authors: Titov, Nickolai , Dear, Blake , Staples, Lauren , Bennett-Levy, James , Klein, Britt , Rapee, Ronald , Shann, Clare , Richards, David , Andersson, Gerhard , Ritterband, Lee , Purtell, Carol , Bezuidenhout, Greg , Johnston, Luke , Nielssen, Olav
- Date: 2015
- Type: Text , Journal article
- Relation: Psychiatric Services Vol. 66, no. 10 (2015), p. 1043-1050
- Full Text: false
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- Description: OBJECTIVE: The main objective of this study was to report the feasibility of delivering online cognitive-behavioral therapy (iCBT) treatments for anxiety and depression in a national public mental health service. METHODS: A prospective noncontrolled cohort study was conducted of all patients who began assessment or treatment at the MindSpot Clinic from January through December 2013. Clinic services were used by a representative cross-section of the Australian population. Mean age at assessment was 36.4+/-13.0 years, and age range was 18-86 years. Patients completed one of four online courses over eight weeks, during which they received weekly support from a therapist via telephone or secure e-mail. Primary outcome measures were the nine-item Patient Health Questionnaire (PHQ-9) and the seven-item Generalized Anxiety Disorder scale (GAD-7) administered at posttreatment and three months posttreatment. RESULTS: A total of 10,293 adults who self-identified as having problems with anxiety or depression commenced assessment, and 7,172 completed the assessment and were eligible for analysis. Of these, 2,049 enrolled in a course and 1,471 completed the course, for a course completion rate of 71.8%. Moderate to large noncontrolled effect sizes (Cohen's d=.67-1.66, 95% confidence interval=.08-2.07) were found from assessment to three-month follow-up. At posttreatment and follow-up, reliable recovery ranged from 46.7% to 51.1%, and deterioration ranged from 1.9% to 3.8%. Mean total therapist time per patient was 111.8+/-61.6 minutes. CONCLUSIONS: The MindSpot Clinic produced treatment outcomes that were comparable to results from published clinical trials of iCBT. This model of service delivery represents an innovative method of providing accessible, low-cost, effective, and acceptable mental health services to many people who currently are not receiving care.