An approach for Ewing test selection to support the clinical assessment of cardiac autonomic neuropathy
- Authors: Stranieri, Andrew , Abawajy, Jemal , Kelarev, Andrei , Huda, Shamsul , Chowdhury, Morshed , Jelinek, Herbert
- Date: 2013
- Type: Text , Journal article
- Relation: Artificial Intelligence in Medicine Vol. 58, no. 3 (2013), p. 185-193
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- Description: Objective: This article addresses the problem of determining optimal sequences of tests for the clinical assessment of cardiac autonomic neuropathy (CAN) We investigate the accuracy of using only one of the recommended Ewing tests to classify CAN and the additional accuracy obtained by adding the remaining tests of the Ewing battery This is important as not all five Ewing tests can always be applied in each situation in practice Methods and material: We used new and unique database of the diabetes screening research initiative project, which is more than ten times larger than the data set used by Ewing in his original investigation of CAN We utilized decision trees and the optimal decision path finder (ODPF) procedure for identifying optimal sequences of tests Results: We present experimental results on the accuracy of using each one of the recommended Ewing tests to classify CAN and the additional accuracy that can be achieved by adding the remaining tests of the Ewing battery We found the best sequences of tests for cost-function equal to the number of tests The accuracies achieved by the initial segments of the optimal sequences for 2, 3 and 4 categories of CAN are 80.80, 91.33, 93.97 and 94.14, and respectively, 79.86, 89.29, 91.16 and 91.76, and 78.90, 86.21, 88.15 and 88.93 They show significant improvement compared to the sequence considered previously in the literature and the mathematical expectations of the accuracies of a random sequence of tests The complete outcomes obtained for all subsets of the Ewing features are required for determining optimal sequences of tests for any cost-function with the use of the ODPF procedure We have also found two most significant additional features that can increase the accuracy when some of the Ewing attributes cannot be obtained Conclusions: The outcomes obtained can be used to determine the optimal sequences of tests for each individual cost-function by following the ODPF procedure The results show that the best single Ewing test for diagnosing CAN is the deep breathing heart rate variation test Optimal sequences found for the cost-function equal to the number of tests guarantee that the best accuracy is achieved after any number of tests and provide an improvement in comparison with the previous ordering of tests or a random sequence © 2013 Elsevier B.V.
- Description: 2003011130
Empirical study of decision trees and ensemble classifiers for monitoring of diabetes patients in pervasive healthcare
- Authors: Kelarev, Andrei , Stranieri, Andrew , Yearwood, John , Jelinek, Herbert
- Date: 2012
- Type: Text , Conference proceedings
- Full Text: false
- Description: Diabetes is a condition requiring continuous everyday monitoring of health related tests. To monitor specific clinical complications one has to find a small set of features to be collected from the sensors and efficient resource-aware algorithms for their processing. This article is concerned with the detection and monitoring of cardiovascular autonomic neuropathy, CAN, in diabetes patients. Using a small set of features identified previously, we carry out an empirical investigation and comparison of several ensemble methods based on decision trees for a novel application of the processing of sensor data from diabetes patients for pervasive health monitoring of CAN. Our experiments relied on an extensive database collected by the Diabetes Complications Screening Research Initiative at Charles Sturt University and concentrated on the particular task of the detection and monitoring of cardiovascular autonomic neuropathy. Most of the features in the database can now be collected using wearable sensors. Our experiments included several essential ensemble methods, a few more advanced and recent techniques, and a novel consensus function. The results show that our novel application of the decision trees in ensemble classifiers for the detection and monitoring of CAN in diabetes patients achieved better performance parameters compared with the outcomes obtained previously in the literature. © 2012 IEEE.
- Description: 2003009675