Fecundity in adult Haemonchus contortus parasites is correlated with abomasal tissue eosinophils and gamma-delta T cells in resistant Canaria Hair Breed sheep
- Authors: Gonzalez, Jorge , Hernandez, Alvaro , Meeusen, Els , Rodríguez, Francisco , Molina, Jose , Jaber, Jose , Raadsma, Herman , Piedrafita, David
- Date: 2011
- Type: Text , Journal article
- Relation: Veterinary Parasitology Vol. 178, no. 3-4 (2011), p. 286-292
- Full Text: false
- Reviewed:
- Description: Canaria Hair Breed (CHB) sheep are more resistant than Canaria sheep (CS) to experimental Haemonchus contortus infection. Protective responses appear effective against the adult stage of the parasite, not as commonly reported in other breeds against the larval stages. In this study we have quantified several abomasal immune cells and correlated these with parasitological variables for each breed. A significant negative correlation between CD4+ T cell numbers and worm burden or length at 28 dpi was seen only in CS sheep. Significant negative correlations for both abomasal eosinophils and
Comparative experimental Haemonchus contortus infection of two sheep breeds native to the Canary Islands
- Authors: Gonzalez, Jorge , Hernandez, Alvaro , Molina, Jose , Fernandez, Antonio , Raadsma, Herman , Meeusen, Els , Piedrafita, David
- Date: 2008
- Type: Text , Journal article
- Relation: Veterinary Parasitology Vol. 153, no. 304 (2008), p. 374-378
- Full Text: false
- Reviewed:
- Description: This study compares the susceptibility to Haemonchus contortus infection in two breeds of sheep endemic to the Canary Islands, the Canaria Hair Breed sheep and the Canaria sheep. Sheep were experimentally infected with 20,000 larvae of H. contortus and animals killed on days 7 and 28 post-infection. No difference between sheep breeds were detected in immature worm counts at days 7 or 28 post-infection. However, in comparison to the Canaria sheep breed, the Canaria Hair Breed sheep showed lower mean faecal egg counts, lower adult worm counts, lower number of eggs in utero and female worm stunting. Overall, these data suggest that the Canaria Hair Breed sheep has a greater resistance to H. contortus infection than Canaria sheep, and that this resistance may act at the level of the adult parasite.