Factors associated with chronic kidney disease in patients with type 2 diabetes in Bangladesh
- Islam, Sheikh, Salehin, Masudus, Zaman, Sojib, Tansi, Tania, Gupta, Rajat
- Authors: Islam, Sheikh , Salehin, Masudus , Zaman, Sojib , Tansi, Tania , Gupta, Rajat
- Date: 2021
- Type: Text , Journal article
- Relation: International Journal of Environmental Research and Public Health Vol. 18, no. 23 (2021), p.
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- Description: Diabetes and chronic kidney disease (CKD) are a major public health burden in low- and middle-income countries. This study aimed to explore factors associated with CKD in patients with type 2 diabetes (T2D) in Bangladesh. A cross-sectional study was conducted among 315 adults with T2D presenting at the outpatient department of Bangladesh Institute of Health Sciences (BIHS) hospital between July 2013 to December 2013. CKD was diagnosed based on the estimated glomerular filtration rate using the ‘Modification of Diet in Renal Disease’ equations and the presence of albu-minuria estimated by the albumin-to-creatinine ratio. Multivariate logistic regression analysis was used to determine the factors associated with CKD. The overall prevalence of CKD among patients with T2D was 21.3%. In the unadjusted model, factors associated with CKD included age 40–49 years (OR: 5.7, 95% CI: 1.3–25.4), age 50–59 years (7.0, 1.6–39), age ≥60 years (7.6, 1.7–34), being female (2.2, 1.2–3.8), being hypertensive (1.9, 1.1–3.5), and household income between 10,001 and 20,000 Bangladeshi taka, BDT (2.9, 1.0–8.2) compared with income ≤10,000 BDT. However, after ad-justment of other covariates, only the duration of hypertension and household income (10,001– 20,000 BDT) remained statistically significant. There is a need to implement policies and programs for early detection and management of hypertension and CKD in T2D patients in Bangladesh. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. **Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Masudus Salehin” is provided in this record**
- Authors: Islam, Sheikh , Salehin, Masudus , Zaman, Sojib , Tansi, Tania , Gupta, Rajat
- Date: 2021
- Type: Text , Journal article
- Relation: International Journal of Environmental Research and Public Health Vol. 18, no. 23 (2021), p.
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- Description: Diabetes and chronic kidney disease (CKD) are a major public health burden in low- and middle-income countries. This study aimed to explore factors associated with CKD in patients with type 2 diabetes (T2D) in Bangladesh. A cross-sectional study was conducted among 315 adults with T2D presenting at the outpatient department of Bangladesh Institute of Health Sciences (BIHS) hospital between July 2013 to December 2013. CKD was diagnosed based on the estimated glomerular filtration rate using the ‘Modification of Diet in Renal Disease’ equations and the presence of albu-minuria estimated by the albumin-to-creatinine ratio. Multivariate logistic regression analysis was used to determine the factors associated with CKD. The overall prevalence of CKD among patients with T2D was 21.3%. In the unadjusted model, factors associated with CKD included age 40–49 years (OR: 5.7, 95% CI: 1.3–25.4), age 50–59 years (7.0, 1.6–39), age ≥60 years (7.6, 1.7–34), being female (2.2, 1.2–3.8), being hypertensive (1.9, 1.1–3.5), and household income between 10,001 and 20,000 Bangladeshi taka, BDT (2.9, 1.0–8.2) compared with income ≤10,000 BDT. However, after ad-justment of other covariates, only the duration of hypertension and household income (10,001– 20,000 BDT) remained statistically significant. There is a need to implement policies and programs for early detection and management of hypertension and CKD in T2D patients in Bangladesh. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. **Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Masudus Salehin” is provided in this record**
Factors influencing place of delivery : evidence from three south-Asian countries
- Rahman, Ms Ashfikur, Rahman, Muhammad Aziz, Rawal, Lal, Paudel, Mohan, Howlader, Md Hasan
- Authors: Rahman, Ms Ashfikur , Rahman, Muhammad Aziz , Rawal, Lal , Paudel, Mohan , Howlader, Md Hasan
- Date: 2021
- Type: Text , Journal article
- Relation: PLoS ONE Vol. 16, no. 4 April (2021), p.
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- Description: Background High maternal mortality is still a significant public health challenge in many countries of the South-Asian region. The majority of maternal deaths occur due to pregnancy and deliveryrelated complications, which can mostly be prevented by safe facility delivery. Due to the paucity of existing evidence, our study aimed to examine the factors associated with place of delivery, including women's preferences for such in three selected South-Asian countries. Methods We extracted data from the most recent demographic and health surveys (DHS) conducted in Bangladesh (2014), Nepal (2016), and Pakistan (2017-18) and analyzed to identify the association between the outcome variable and socio-demographic characteristics. A total of 16,429 women from Bangladesh (4278; mean age 24.57 years), Nepal (3962; mean age 26.35 years), and Pakistan (8189; mean age 29.57 years) were included in this study. Following descriptive analyses, bivariate and multivariate logistic regressions were conducted. Results Overall, the prevalence of facility-based delivery was 40%, 62%, and 69% in Bangladesh, Nepal, and Pakistan, respectively. Inequity in utilizing facility-based delivery was observed for women in the highest wealth quintile. Participants from Urban areas, educated, middle and upper household economic status, and with high antenatal care (ANC) visits were significantly associated with facility-based delivery in all three countries. Interestingly, watching TV was also found as a strong determinant for facility-based delivery in Bangladesh (aOR = 1.31, 95% CI:1.09-1.56, P = 0.003), Nepal (aOR = 1.42, 95% CI:1.20-1.67, P<0.001) and Pakistan (aOR = 1.17, 95% CI: 1.03-1.32, P = 0.013). Higher education of husband was a significant predictor for facility delivery in Bangladesh (aOR = 1.73, 95% CI:1.27-2.35, P = 0.001) and Pakistan (aOR = 1.19, 95% CI: 0.99-1.43, P = 0.065); husband's occupation was also a significant factor in Bangladesh (aOR = 1.30, 95% CI:1.04-1.61, P = 0.020) and Nepal (aOR = 1.26, 95% CI:1.01-1.58, P = 0.041). Conclusion Our findings suggest that the educational status of both women and their husbands, household economic situation, and the number of ANC visits influenced the place of delivery. There is an urgent need to promote facility delivery by building more birthing facilities, training and deployment of skilled birth attendants in rural and hard-to-reach areas, ensuring compulsory female education for all women, encouraging more ANC visits, and providing financial incentives for facility deliveries. There is a need to promote facility delivery by encouraging health facility visits through utilizing social networks and continuing mass media campaigns. Ensuring adequate Government funding for free maternal and newborn health care and local community involvement is crucial for reducing maternal and neonatal mortality and achieving sustainable development goals in this region. © 2021 Rahman et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. *Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Muhammad Rahman” is provided in this record**
- Authors: Rahman, Ms Ashfikur , Rahman, Muhammad Aziz , Rawal, Lal , Paudel, Mohan , Howlader, Md Hasan
- Date: 2021
- Type: Text , Journal article
- Relation: PLoS ONE Vol. 16, no. 4 April (2021), p.
- Full Text:
- Reviewed:
- Description: Background High maternal mortality is still a significant public health challenge in many countries of the South-Asian region. The majority of maternal deaths occur due to pregnancy and deliveryrelated complications, which can mostly be prevented by safe facility delivery. Due to the paucity of existing evidence, our study aimed to examine the factors associated with place of delivery, including women's preferences for such in three selected South-Asian countries. Methods We extracted data from the most recent demographic and health surveys (DHS) conducted in Bangladesh (2014), Nepal (2016), and Pakistan (2017-18) and analyzed to identify the association between the outcome variable and socio-demographic characteristics. A total of 16,429 women from Bangladesh (4278; mean age 24.57 years), Nepal (3962; mean age 26.35 years), and Pakistan (8189; mean age 29.57 years) were included in this study. Following descriptive analyses, bivariate and multivariate logistic regressions were conducted. Results Overall, the prevalence of facility-based delivery was 40%, 62%, and 69% in Bangladesh, Nepal, and Pakistan, respectively. Inequity in utilizing facility-based delivery was observed for women in the highest wealth quintile. Participants from Urban areas, educated, middle and upper household economic status, and with high antenatal care (ANC) visits were significantly associated with facility-based delivery in all three countries. Interestingly, watching TV was also found as a strong determinant for facility-based delivery in Bangladesh (aOR = 1.31, 95% CI:1.09-1.56, P = 0.003), Nepal (aOR = 1.42, 95% CI:1.20-1.67, P<0.001) and Pakistan (aOR = 1.17, 95% CI: 1.03-1.32, P = 0.013). Higher education of husband was a significant predictor for facility delivery in Bangladesh (aOR = 1.73, 95% CI:1.27-2.35, P = 0.001) and Pakistan (aOR = 1.19, 95% CI: 0.99-1.43, P = 0.065); husband's occupation was also a significant factor in Bangladesh (aOR = 1.30, 95% CI:1.04-1.61, P = 0.020) and Nepal (aOR = 1.26, 95% CI:1.01-1.58, P = 0.041). Conclusion Our findings suggest that the educational status of both women and their husbands, household economic situation, and the number of ANC visits influenced the place of delivery. There is an urgent need to promote facility delivery by building more birthing facilities, training and deployment of skilled birth attendants in rural and hard-to-reach areas, ensuring compulsory female education for all women, encouraging more ANC visits, and providing financial incentives for facility deliveries. There is a need to promote facility delivery by encouraging health facility visits through utilizing social networks and continuing mass media campaigns. Ensuring adequate Government funding for free maternal and newborn health care and local community involvement is crucial for reducing maternal and neonatal mortality and achieving sustainable development goals in this region. © 2021 Rahman et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. *Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Muhammad Rahman” is provided in this record**
- Hu, Yang, Fest, Benedikt, Swearer, Stephen, Arndt, Stefan
- Authors: Hu, Yang , Fest, Benedikt , Swearer, Stephen , Arndt, Stefan
- Date: 2021
- Type: Text , Journal article
- Relation: Estuarine, Coastal and Shelf Science Vol. 259, no. (2021), p.
- Full Text: false
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- Description: Mangrove ecosystems have the potential to store large amounts of carbon but detailed studies on the fine scale spatial variability of biomass components and sediment organic carbon (SOC) and their relationships are lacking. Here we investigated the fine-scale spatial variation of SOC, aboveground and belowground biomass using systematic grid sampling in a temperate Avicennia marina ((Forssk.) Vierh) forest in Australia. We estimated aboveground biomass in a 9 × 9 sampling grid within a 0.16 ha plot and measured SOC, fine root biomass and necromass down to 1 m at 81 sampling points in an A. marina forest in Western Port Bay near Melbourne, Australia. We detected large differences in all measured carbon pools. SOC increased from low to high intertidal position but showed no consistent trend with depth. Aboveground biomass carbon was highly variable (mean 84 ± 56 Mg C ha
Healthy waterways and ecologically sustainable cities in Beijing-Tianjin-Hebei urban agglomeration (northern China) : challenges and future directions
- Kattel, Giri, Reeves, Jessica, Western, Andrew, Zhang, Wenjing, Dowling, Kim
- Authors: Kattel, Giri , Reeves, Jessica , Western, Andrew , Zhang, Wenjing , Dowling, Kim
- Date: 2021
- Type: Text , Journal article
- Relation: Wiley Interdisciplinary Reviews: Water Vol. 8, no. 2 (2021), p.
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- Description: The cities across the northern dry region of China are exposed to multiple sustainability challenges. Beijing-Hebei-Tianjin (BTH) urban agglomeration, for example, experiences severe water shortages due to rapidly expanding urban populations, industrial use, and irrigation-intensive agriculture. Climate change has further threatened water resources security. Overuse of water resources to meet the demand of various water sectors has far-reaching health and environmental implications including ecosystem sustainability. Surface water and groundwater pollution present public health risks. Despite the extraordinary policies and efforts being made and implemented by the Government of China, the BTH region currently lacks coordination among stakeholders leading to poor water governance. Consultation among scientists, engineers and stakeholders on regional water security issues is crucial and must be frequent and inclusive. An international symposium was held in Shijiazhuang in early November 2019 to identify some of the key water security challenges and scope of an idealized future eco-city in the region by developing a sustainability framework. This work drew on experiences from across China and beyond. Scientists agree that integration of science, technology, and governance within an appropriate policy framework was particularly significant for combating the issue of water insecurity, including in the region's newly developed city, Xiong'an New Area. An emerging concept, “Healthy Waterways and Ecologically Sustainable Cities” which integrates social, ecological and hydrological systems and acts as an important pathway for sustainability in the 21st century was proposed in the symposium to tackle the problems in the region. This high level biophysical and cultural concept empowers development goals and promotes human health and wellbeing. The framework on healthy waterways and ecologically sustainable cities can overcome sustainability challenges by resolving water resource management issues in BTH in a holistic way. To implement the concept, we strongly recommend the utilization of evidence-based scientific research and institutional cooperation including national and international collaborations to achieve the Healthy Waterways and Ecologically Sustainable Cities goal in the BTH in future. This article is categorized under: Water and Life > Conservation, Management, and Awareness. © 2020 Wiley Periodicals LLC. **Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Giri Kattel, Jessica Reeves and Kim Dowling” is provided in this record**
- Authors: Kattel, Giri , Reeves, Jessica , Western, Andrew , Zhang, Wenjing , Dowling, Kim
- Date: 2021
- Type: Text , Journal article
- Relation: Wiley Interdisciplinary Reviews: Water Vol. 8, no. 2 (2021), p.
- Full Text:
- Reviewed:
- Description: The cities across the northern dry region of China are exposed to multiple sustainability challenges. Beijing-Hebei-Tianjin (BTH) urban agglomeration, for example, experiences severe water shortages due to rapidly expanding urban populations, industrial use, and irrigation-intensive agriculture. Climate change has further threatened water resources security. Overuse of water resources to meet the demand of various water sectors has far-reaching health and environmental implications including ecosystem sustainability. Surface water and groundwater pollution present public health risks. Despite the extraordinary policies and efforts being made and implemented by the Government of China, the BTH region currently lacks coordination among stakeholders leading to poor water governance. Consultation among scientists, engineers and stakeholders on regional water security issues is crucial and must be frequent and inclusive. An international symposium was held in Shijiazhuang in early November 2019 to identify some of the key water security challenges and scope of an idealized future eco-city in the region by developing a sustainability framework. This work drew on experiences from across China and beyond. Scientists agree that integration of science, technology, and governance within an appropriate policy framework was particularly significant for combating the issue of water insecurity, including in the region's newly developed city, Xiong'an New Area. An emerging concept, “Healthy Waterways and Ecologically Sustainable Cities” which integrates social, ecological and hydrological systems and acts as an important pathway for sustainability in the 21st century was proposed in the symposium to tackle the problems in the region. This high level biophysical and cultural concept empowers development goals and promotes human health and wellbeing. The framework on healthy waterways and ecologically sustainable cities can overcome sustainability challenges by resolving water resource management issues in BTH in a holistic way. To implement the concept, we strongly recommend the utilization of evidence-based scientific research and institutional cooperation including national and international collaborations to achieve the Healthy Waterways and Ecologically Sustainable Cities goal in the BTH in future. This article is categorized under: Water and Life > Conservation, Management, and Awareness. © 2020 Wiley Periodicals LLC. **Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Giri Kattel, Jessica Reeves and Kim Dowling” is provided in this record**
Identifying tobacco retailers in the absence of a licensing system : lessons from Australia
- Baker, John, Masood, Mohd, Rahman, Muhammad Aziz, Thornton, Lukar, Begg, Stephen
- Authors: Baker, John , Masood, Mohd , Rahman, Muhammad Aziz , Thornton, Lukar , Begg, Stephen
- Date: 2021
- Type: Text , Journal article
- Relation: Tobacco Control Vol. 31, no. 4 (2021), p. 543-548
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- Description: ObjectivesTo estimate the proportion of retailers that sell tobacco in the absence of appropriate local government oversight, and to describe the characteristics by which they differ from those that can expect to receive such oversight.MethodsA database of listed tobacco retailers was obtained from a regional Victorian local government. Potential unlisted tobacco retailers were added using online searches, and attempts to visit all retailers were undertaken. GPS coordinates and sales type information of retailers that sold tobacco were recorded and attached to neighbourhood-level data on socioeconomic disadvantage and smoking prevalence using ArcMap. Logistic regression analyses, χ2 tests and t-tests were undertaken to explore differences in numbers of listed and unlisted retailers by business and neighbourhood-level characteristics.ResultsOf 125 confirmed tobacco retailers, 43.2% were trading potentially without government oversight. Significant differences were found between listed and unlisted retailers by primary business type (p<0.001), and sales type (p<0.001) but not by the other characteristics.ConclusionsThe database of tobacco retailers was inaccurate in two ways: (1) a number of listed retailers no longer operated or sold tobacco, and (2) 43.2% of businesses confirmed as selling tobacco were missing. As no form of licensing system exists in Victoria, it is difficult to identify the number of retailers operating, or to determine how many receive formal regulatory oversight. A positive licensing system is recommended to regulate the sale of tobacco and to generate a comprehensive database of retailers, similar to that which exists for food registration, gaming and liquor-licensed premises.
- Authors: Baker, John , Masood, Mohd , Rahman, Muhammad Aziz , Thornton, Lukar , Begg, Stephen
- Date: 2021
- Type: Text , Journal article
- Relation: Tobacco Control Vol. 31, no. 4 (2021), p. 543-548
- Full Text:
- Reviewed:
- Description: ObjectivesTo estimate the proportion of retailers that sell tobacco in the absence of appropriate local government oversight, and to describe the characteristics by which they differ from those that can expect to receive such oversight.MethodsA database of listed tobacco retailers was obtained from a regional Victorian local government. Potential unlisted tobacco retailers were added using online searches, and attempts to visit all retailers were undertaken. GPS coordinates and sales type information of retailers that sold tobacco were recorded and attached to neighbourhood-level data on socioeconomic disadvantage and smoking prevalence using ArcMap. Logistic regression analyses, χ2 tests and t-tests were undertaken to explore differences in numbers of listed and unlisted retailers by business and neighbourhood-level characteristics.ResultsOf 125 confirmed tobacco retailers, 43.2% were trading potentially without government oversight. Significant differences were found between listed and unlisted retailers by primary business type (p<0.001), and sales type (p<0.001) but not by the other characteristics.ConclusionsThe database of tobacco retailers was inaccurate in two ways: (1) a number of listed retailers no longer operated or sold tobacco, and (2) 43.2% of businesses confirmed as selling tobacco were missing. As no form of licensing system exists in Victoria, it is difficult to identify the number of retailers operating, or to determine how many receive formal regulatory oversight. A positive licensing system is recommended to regulate the sale of tobacco and to generate a comprehensive database of retailers, similar to that which exists for food registration, gaming and liquor-licensed premises.
Impact of COVID-19 pandemic on mobility in ten countries and associated perceived risk for all transport modes
- Barbieri, Diego, Lou, Baowen, Passavanti, Marco, Hui, Cang, Lam, Louisa
- Authors: Barbieri, Diego , Lou, Baowen , Passavanti, Marco , Hui, Cang , Lam, Louisa
- Date: 2021
- Type: Text , Journal article
- Relation: PLoS ONE Vol. 16, no. 2 (2021), p.
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- Description: The restrictive measures implemented in response to the COVID-19 pandemic have triggered sudden massive changes to travel behaviors of people all around the world. This study examines the individual mobility patterns for all transport modes (walk, bicycle, motorcycle, car driven alone, car driven in company, bus, subway, tram, train, airplane) before and during the restrictions adopted in ten countries on six continents: Australia, Brazil, China, Ghana, India, Iran, Italy, Norway, South Africa and the United States. This cross-country study also aims at understanding the predictors of protective behaviors related to the transport sector and COVID-19. Findings hinge upon an online survey conducted in May 2020 (N = 9,394). The empirical results quantify tremendous disruptions for both commuting and non-commuting travels, highlighting substantial reductions in the frequency of all types of trips and use of all modes. In terms of potential virus spread, airplanes and buses are perceived to be the riskiest transport modes, while avoidance of public transport is consistently found across the countries. According to the Protection Motivation Theory, the study sheds new light on the fact that two indicators, namely income inequality, expressed as Gini index, and the reported number of deaths due to COVID-19 per 100,000 inhabitants, aggravate respondents’ perceptions. This research indicates that socio-economic inequality and morbidity are not only related to actual health risks, as well documented in the relevant literature, but also to the perceived risks. These findings document the global impact of the COVID-19 crisis as well as provide guidance for transportation practitioners in developing future strategies. © 2021 Barbieri et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. *Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Louisa Lam” is provided in this record**
- Authors: Barbieri, Diego , Lou, Baowen , Passavanti, Marco , Hui, Cang , Lam, Louisa
- Date: 2021
- Type: Text , Journal article
- Relation: PLoS ONE Vol. 16, no. 2 (2021), p.
- Full Text:
- Reviewed:
- Description: The restrictive measures implemented in response to the COVID-19 pandemic have triggered sudden massive changes to travel behaviors of people all around the world. This study examines the individual mobility patterns for all transport modes (walk, bicycle, motorcycle, car driven alone, car driven in company, bus, subway, tram, train, airplane) before and during the restrictions adopted in ten countries on six continents: Australia, Brazil, China, Ghana, India, Iran, Italy, Norway, South Africa and the United States. This cross-country study also aims at understanding the predictors of protective behaviors related to the transport sector and COVID-19. Findings hinge upon an online survey conducted in May 2020 (N = 9,394). The empirical results quantify tremendous disruptions for both commuting and non-commuting travels, highlighting substantial reductions in the frequency of all types of trips and use of all modes. In terms of potential virus spread, airplanes and buses are perceived to be the riskiest transport modes, while avoidance of public transport is consistently found across the countries. According to the Protection Motivation Theory, the study sheds new light on the fact that two indicators, namely income inequality, expressed as Gini index, and the reported number of deaths due to COVID-19 per 100,000 inhabitants, aggravate respondents’ perceptions. This research indicates that socio-economic inequality and morbidity are not only related to actual health risks, as well documented in the relevant literature, but also to the perceived risks. These findings document the global impact of the COVID-19 crisis as well as provide guidance for transportation practitioners in developing future strategies. © 2021 Barbieri et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. *Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Louisa Lam” is provided in this record**
Impact of domestic travel restrictions on transmission of COVID-19 infection using public transportation network approach
- Murano, Yayoi, Ueno, Ryo, Shi, Shoi, Kawashima, Takayuki, Nguyen, Huy
- Authors: Murano, Yayoi , Ueno, Ryo , Shi, Shoi , Kawashima, Takayuki , Nguyen, Huy
- Date: 2021
- Type: Text , Journal article
- Relation: Scientific Reports Vol. 11, no. 1 (2021), p.
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- Description: The international spread of COVID-19 infection has attracted global attention, but the impact of local or domestic travel restriction on public transportation network remains unclear. Passenger volume data for the domestic public transportation network in Japan and the time at which the first confirmed COVID-19 case was observed in each prefecture were extracted from public data sources. A survival approach in which a hazard was modeled as a function of the closeness centrality on the network was utilized to estimate the risk of importation of COVID-19 in each prefecture. A total of 46 prefectures with imported cases were identified. Hypothetical scenario analyses indicated that both strategies of locking down the metropolitan areas and restricting domestic airline travel would be equally effective in reducing the risk of importation of COVID-19. While caution is necessary that the data were limited to June 2020 when the pandemic was in its initial stage and that no other virus spreading routes have been considered, domestic travel restrictions were effective to prevent the spread of COVID-19 on public transportation network in Japan. Instead of lockdown that might seriously damage the economy, milder travel restrictions could have the similar impact on controlling the domestic transmission of COVID-19. © 2021, The Author(s).
- Authors: Murano, Yayoi , Ueno, Ryo , Shi, Shoi , Kawashima, Takayuki , Nguyen, Huy
- Date: 2021
- Type: Text , Journal article
- Relation: Scientific Reports Vol. 11, no. 1 (2021), p.
- Full Text:
- Reviewed:
- Description: The international spread of COVID-19 infection has attracted global attention, but the impact of local or domestic travel restriction on public transportation network remains unclear. Passenger volume data for the domestic public transportation network in Japan and the time at which the first confirmed COVID-19 case was observed in each prefecture were extracted from public data sources. A survival approach in which a hazard was modeled as a function of the closeness centrality on the network was utilized to estimate the risk of importation of COVID-19 in each prefecture. A total of 46 prefectures with imported cases were identified. Hypothetical scenario analyses indicated that both strategies of locking down the metropolitan areas and restricting domestic airline travel would be equally effective in reducing the risk of importation of COVID-19. While caution is necessary that the data were limited to June 2020 when the pandemic was in its initial stage and that no other virus spreading routes have been considered, domestic travel restrictions were effective to prevent the spread of COVID-19 on public transportation network in Japan. Instead of lockdown that might seriously damage the economy, milder travel restrictions could have the similar impact on controlling the domestic transmission of COVID-19. © 2021, The Author(s).
Indoor emission sources detection by pollutants interaction analysis
- Pang, Shaoning, Song, Lei, Sarrafzadeh, Abdolhossein, Coulson, Guy, Longley, Ian, Olivares, Gustavo
- Authors: Pang, Shaoning , Song, Lei , Sarrafzadeh, Abdolhossein , Coulson, Guy , Longley, Ian , Olivares, Gustavo
- Date: 2021
- Type: Text , Journal article
- Relation: Applied Sciences (Switzerland) Vol. 11, no. 16 (2021), p.
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- Description: This study employs the correlation coefficients technique to support emission sources detection for indoor environments. Unlike existing methods analyzing merely primary pollution, we consider alternatively the secondary pollution (i.e., chemical reactions between pollutants in addition to pollutant level), and calculate intra pollutants correlation coefficients for characterizing and distinguishing emission events. Extensive experiments show that seven major indoor emission sources are identified by the proposed method, including (1) frying canola oil on electric hob, (2) frying olive oil on an electric hob, (3) frying olive oil on a gas hob, (4) spray of household pesticide, (5) lighting a cigarette and allowing it to smoulder, (6) no activities, and (7) venting session. Furthermore, our method improves the detection accuracy by a support vector machine compared to without data filtering and applying typical feature extraction methods such as PCA and LDA. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
- Authors: Pang, Shaoning , Song, Lei , Sarrafzadeh, Abdolhossein , Coulson, Guy , Longley, Ian , Olivares, Gustavo
- Date: 2021
- Type: Text , Journal article
- Relation: Applied Sciences (Switzerland) Vol. 11, no. 16 (2021), p.
- Full Text:
- Reviewed:
- Description: This study employs the correlation coefficients technique to support emission sources detection for indoor environments. Unlike existing methods analyzing merely primary pollution, we consider alternatively the secondary pollution (i.e., chemical reactions between pollutants in addition to pollutant level), and calculate intra pollutants correlation coefficients for characterizing and distinguishing emission events. Extensive experiments show that seven major indoor emission sources are identified by the proposed method, including (1) frying canola oil on electric hob, (2) frying olive oil on an electric hob, (3) frying olive oil on a gas hob, (4) spray of household pesticide, (5) lighting a cigarette and allowing it to smoulder, (6) no activities, and (7) venting session. Furthermore, our method improves the detection accuracy by a support vector machine compared to without data filtering and applying typical feature extraction methods such as PCA and LDA. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
- Eklund, Erik, Holm, Antoinette, Reeves, Keir
- Authors: Eklund, Erik , Holm, Antoinette , Reeves, Keir
- Date: 2021
- Type: Text , Journal article
- Relation: Journal of Australian Studies Vol. 45, no. 4 (2021), p. 524-542
- Full Text: false
- Reviewed:
- Description: This article considers the comparative standing of industrial heritage in two distinctive Australian regional contexts. With a focus on the agents and actors in the heritage-making process, we outline the development of a case for heritage in the mining town of Broken Hill in far western New South Wales, which gained momentum soon after the local mines began a steady decline in the early 1970s. Broken Hill has, to some extent, adapted its mining and labour heritage to form a viable element of the town’s current identity and economic base, especially by seeing those individual sites as part of a heritage landscape. We also consider industrial heritage in the Latrobe Valley in Victoria, a brown coal mining and electricity-generation hub where industrial and mining employment has declined much more recently. Reflecting on these changing political policies and industry privatisation in the early 1990s, we examine the impact on industrial heritage in a region typified by mining and power generation. © 2021 International Australian Studies Association.
Kallistatin limits abdominal aortic aneurysm by attenuating generation of reactive oxygen species and apoptosis
- Krishna, Smriti, Li, Jiaze, Wang, Yutang, Moran, Corey, Trollope, Alexandra
- Authors: Krishna, Smriti , Li, Jiaze , Wang, Yutang , Moran, Corey , Trollope, Alexandra
- Date: 2021
- Type: Text , Journal article
- Relation: Scientific Reports Vol. 11, no. 1 (2021), p.
- Full Text:
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- Description: Inflammation, vascular smooth muscle cell apoptosis and oxidative stress are believed to play important roles in abdominal aortic aneurysm (AAA) pathogenesis. Human kallistatin (KAL; gene SERPINA4) is a serine proteinase inhibitor previously shown to inhibit inflammation, apoptosis and oxidative stress. The aim of this study was to investigate the role of KAL in AAA through studies in experimental mouse models and patients. Serum KAL concentration was negatively associated with the diagnosis and growth of human AAA. Transgenic overexpression of the human KAL gene (KS-Tg) or administration of recombinant human KAL (rhKAL) inhibited AAA in the calcium phosphate (CaPO4) and subcutaneous angiotensin II (AngII) infusion mouse models. Upregulation of KAL in both models resulted in reduction in the severity of aortic elastin degradation, reduced markers of oxidative stress and less vascular smooth muscle apoptosis within the aorta. Administration of rhKAL to vascular smooth muscle cells incubated in the presence of AngII or in human AAA thrombus-conditioned media reduced apoptosis and downregulated markers of oxidative stress. These effects of KAL were associated with upregulation of Sirtuin 1 activity within the aortas of both KS-Tg mice and rodents receiving rhKAL. These results suggest KAL-Sirtuin 1 signalling limits aortic wall remodelling and aneurysm development through reductions in oxidative stress and vascular smooth muscle cell apoptosis. Upregulating KAL may be a novel therapeutic strategy for AAA. © 2021, The Author(s).
- Authors: Krishna, Smriti , Li, Jiaze , Wang, Yutang , Moran, Corey , Trollope, Alexandra
- Date: 2021
- Type: Text , Journal article
- Relation: Scientific Reports Vol. 11, no. 1 (2021), p.
- Full Text:
- Reviewed:
- Description: Inflammation, vascular smooth muscle cell apoptosis and oxidative stress are believed to play important roles in abdominal aortic aneurysm (AAA) pathogenesis. Human kallistatin (KAL; gene SERPINA4) is a serine proteinase inhibitor previously shown to inhibit inflammation, apoptosis and oxidative stress. The aim of this study was to investigate the role of KAL in AAA through studies in experimental mouse models and patients. Serum KAL concentration was negatively associated with the diagnosis and growth of human AAA. Transgenic overexpression of the human KAL gene (KS-Tg) or administration of recombinant human KAL (rhKAL) inhibited AAA in the calcium phosphate (CaPO4) and subcutaneous angiotensin II (AngII) infusion mouse models. Upregulation of KAL in both models resulted in reduction in the severity of aortic elastin degradation, reduced markers of oxidative stress and less vascular smooth muscle apoptosis within the aorta. Administration of rhKAL to vascular smooth muscle cells incubated in the presence of AngII or in human AAA thrombus-conditioned media reduced apoptosis and downregulated markers of oxidative stress. These effects of KAL were associated with upregulation of Sirtuin 1 activity within the aortas of both KS-Tg mice and rodents receiving rhKAL. These results suggest KAL-Sirtuin 1 signalling limits aortic wall remodelling and aneurysm development through reductions in oxidative stress and vascular smooth muscle cell apoptosis. Upregulating KAL may be a novel therapeutic strategy for AAA. © 2021, The Author(s).
Modulation of TCR signalling components occurs prior to positive selection and lineage commitment in iNKT cells
- Dinh, Xuyen, Stanley, Dragana, Smith, Letitia, Moreau, Morgane, Berzins, Stuart
- Authors: Dinh, Xuyen , Stanley, Dragana , Smith, Letitia , Moreau, Morgane , Berzins, Stuart
- Date: 2021
- Type: Text , Journal article
- Relation: Scientific Reports Vol. 11, no. 1 (2021), p.
- Full Text:
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- Description: iNKT cells play a critical role in controlling the strength and character of adaptive and innate immune responses. Their unique functional characteristics are induced by a transcriptional program initiated by positive selection mediated by CD1d expressed by CD4+CD8+ (double positive, DP) thymocytes. Here, using a novel Vα14 TCR transgenic strain bearing greatly expanded numbers of CD24hiCD44loNKT cells, we examined transcriptional events in four immature thymic iNKT cell subsets. A transcriptional regulatory network approach identified transcriptional changes in proximal components of the TCR signalling cascade in DP NKT cells. Subsequently, positive and negative selection, and lineage commitment, occurred at the transition from DP NKT to CD4 NKT. Thus, this study introduces previously unrecognised steps in early NKT cell development, and separates the events associated with modulation of the T cell signalling cascade prior to changes associated with positive selection and lineage commitment. © 2021, The Author(s). **Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Stuart Berzins” is provided in this record**
- Authors: Dinh, Xuyen , Stanley, Dragana , Smith, Letitia , Moreau, Morgane , Berzins, Stuart
- Date: 2021
- Type: Text , Journal article
- Relation: Scientific Reports Vol. 11, no. 1 (2021), p.
- Full Text:
- Reviewed:
- Description: iNKT cells play a critical role in controlling the strength and character of adaptive and innate immune responses. Their unique functional characteristics are induced by a transcriptional program initiated by positive selection mediated by CD1d expressed by CD4+CD8+ (double positive, DP) thymocytes. Here, using a novel Vα14 TCR transgenic strain bearing greatly expanded numbers of CD24hiCD44loNKT cells, we examined transcriptional events in four immature thymic iNKT cell subsets. A transcriptional regulatory network approach identified transcriptional changes in proximal components of the TCR signalling cascade in DP NKT cells. Subsequently, positive and negative selection, and lineage commitment, occurred at the transition from DP NKT to CD4 NKT. Thus, this study introduces previously unrecognised steps in early NKT cell development, and separates the events associated with modulation of the T cell signalling cascade prior to changes associated with positive selection and lineage commitment. © 2021, The Author(s). **Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Stuart Berzins” is provided in this record**
Morally excused but socially excluded: Denying agency through the defense of mental impairment
- de Vel-Palumbo, Melissa, Schein, Chelsea, Ferguson, Rose, Chang, Melissa, Bastian, Brock
- Authors: de Vel-Palumbo, Melissa , Schein, Chelsea , Ferguson, Rose , Chang, Melissa , Bastian, Brock
- Date: 2021
- Type: Text , Journal article
- Relation: PloS one Vol. 16, no. 6 (2021), p. e0252586-e0252586
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- Description: Defendants can deny they have agency, and thus responsibility, for a crime by using a defense of mental impairment. We argue that although this strategy may help defendants evade blame, it may carry longer-term social costs, as lay people's perceptions of a person's agency might determine some of the moral rights they grant them. In this registered report protocol, we seek to expand upon preliminary findings from two pilot studies to examine how and why those using the defense of mental impairment are seen as less deserving of certain rights. The proposed study uses a hypothetical vignette design, varying the type of mental impairment, type of crime, and type of sentence. Our design for the registered study improves on various aspects of our pilot studies and aims to rigorously test the reliability and credibility of our model. The findings have implications for defendants claiming reduced agency through legal defenses, as well as for the broader study of moral rights and mind perception.
- Authors: de Vel-Palumbo, Melissa , Schein, Chelsea , Ferguson, Rose , Chang, Melissa , Bastian, Brock
- Date: 2021
- Type: Text , Journal article
- Relation: PloS one Vol. 16, no. 6 (2021), p. e0252586-e0252586
- Full Text:
- Reviewed:
- Description: Defendants can deny they have agency, and thus responsibility, for a crime by using a defense of mental impairment. We argue that although this strategy may help defendants evade blame, it may carry longer-term social costs, as lay people's perceptions of a person's agency might determine some of the moral rights they grant them. In this registered report protocol, we seek to expand upon preliminary findings from two pilot studies to examine how and why those using the defense of mental impairment are seen as less deserving of certain rights. The proposed study uses a hypothetical vignette design, varying the type of mental impairment, type of crime, and type of sentence. Our design for the registered study improves on various aspects of our pilot studies and aims to rigorously test the reliability and credibility of our model. The findings have implications for defendants claiming reduced agency through legal defenses, as well as for the broader study of moral rights and mind perception.
Not a pivot, but a pirouette : a panel presentation about the Arts Academy online in a time of pandemic
- Beddie, Melanie, Crowley, Anthony, Durban, Kim, Hall, Ross
- Authors: Beddie, Melanie , Crowley, Anthony , Durban, Kim , Hall, Ross
- Date: 2021
- Type: Text , Journal article
- Relation: International Journal of Contemporary Humanities Vol. 5, no. 1 (2021), p. 1
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- Authors: Beddie, Melanie , Crowley, Anthony , Durban, Kim , Hall, Ross
- Date: 2021
- Type: Text , Journal article
- Relation: International Journal of Contemporary Humanities Vol. 5, no. 1 (2021), p. 1
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Perceived change in tobacco use and its associated factors among older adults residing in rohingya refugee camps during the covid-19 pandemic in Bangladesh
- Mistry, Sabuj, Ali, Arm Mehrab, Yadav, Uday, Huda, Md Nazmul, Rahman, Muhammad Aziz
- Authors: Mistry, Sabuj , Ali, Arm Mehrab , Yadav, Uday , Huda, Md Nazmul , Rahman, Muhammad Aziz
- Date: 2021
- Type: Text , Journal article
- Relation: International Journal of Environmental Research and Public Health Vol. 18, no. 23 (2021), p.
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- Description: This study explored the perceived change in tobacco use during the COVID-19 pandemic and its associated factors among older adults residing in Rohingya refugee camps, also referred to as Forcibly Displaced Myanmar Nationals in Bangladesh. The study followed a cross-sectional design and was conducted in October 2020 among 416 older adults aged 60 years and above. A purposive sampling technique was applied to identify eligible participants, and face-to-face interviews were conducted using a pre-tested semi-structured questionnaire to collect the data. Participants were asked if they noted any change in their tobacco use patterns (smoking or smokeless tobacco) during the COVID-19 pandemic compared to pre-pandemic. Binary logistic regression models determined the factors associated with the perceived change in tobacco use. More than one in five participants (22.4%) were current tobacco users, of whom 40.8% reported a perceived increase in tobacco use during the COVID-19 pandemic. Adjusted analysis revealed that participants who were concerned about COVID-19 had significantly (p < 0.05) lower odds of perceived increase in tobacco use (aOR = 0.22, 95% CI: 0.06–0.73), while older adults who were overwhelmed by COVID-19 (aOR = 0.26, 95% CI: 0.06–1.18) and communicated less frequently with others during the pandemic than before (aOR = 0.19, 95% CI: 0.03–1.20) had marginally significantly (p < 0.1) lower odds of perceived increase in tobacco use during this pandemic. Relevant stakeholders, policymakers, and practitioners need to focus on strengthening awareness-raising initiatives as part of an emergency preparedness plan to control tobacco use during such a crisis period. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. **Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Muhammad Aziz Rahman” is provided in this record**
- Authors: Mistry, Sabuj , Ali, Arm Mehrab , Yadav, Uday , Huda, Md Nazmul , Rahman, Muhammad Aziz
- Date: 2021
- Type: Text , Journal article
- Relation: International Journal of Environmental Research and Public Health Vol. 18, no. 23 (2021), p.
- Full Text:
- Reviewed:
- Description: This study explored the perceived change in tobacco use during the COVID-19 pandemic and its associated factors among older adults residing in Rohingya refugee camps, also referred to as Forcibly Displaced Myanmar Nationals in Bangladesh. The study followed a cross-sectional design and was conducted in October 2020 among 416 older adults aged 60 years and above. A purposive sampling technique was applied to identify eligible participants, and face-to-face interviews were conducted using a pre-tested semi-structured questionnaire to collect the data. Participants were asked if they noted any change in their tobacco use patterns (smoking or smokeless tobacco) during the COVID-19 pandemic compared to pre-pandemic. Binary logistic regression models determined the factors associated with the perceived change in tobacco use. More than one in five participants (22.4%) were current tobacco users, of whom 40.8% reported a perceived increase in tobacco use during the COVID-19 pandemic. Adjusted analysis revealed that participants who were concerned about COVID-19 had significantly (p < 0.05) lower odds of perceived increase in tobacco use (aOR = 0.22, 95% CI: 0.06–0.73), while older adults who were overwhelmed by COVID-19 (aOR = 0.26, 95% CI: 0.06–1.18) and communicated less frequently with others during the pandemic than before (aOR = 0.19, 95% CI: 0.03–1.20) had marginally significantly (p < 0.1) lower odds of perceived increase in tobacco use during this pandemic. Relevant stakeholders, policymakers, and practitioners need to focus on strengthening awareness-raising initiatives as part of an emergency preparedness plan to control tobacco use during such a crisis period. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. **Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Muhammad Aziz Rahman” is provided in this record**
Performing the bounds of responsibility
- Authors: Berger, Karen
- Date: 2021
- Type: Text , Journal article
- Relation: Humanities Vol. 10, no. 4 (2021), p. 112
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- Description: This paper investigates border-making dynamics in the two political arenas where my subjectivity is most acutely implicated across time—the Jewish Holocaust (as an intergenerational victim) and the Aboriginal genocide (as an unwitting beneficiary). Albeit that there are many differences between the drivers of antisemitism and racism against Indigenous Australians, I investigate both of these racist structures through the lens of border-thinking as theorised by Walter Mignolo as a method of decolonisation (2006). The article has been formatted as an example of discursive border-crossing by juxtaposing theoretical ideas (particularly inspired by Zygmunt Bauman and Deborah Bird Rose) with interjections from my personal journal. I explore my own performative storytelling as a means for me to take responsibility to question power structures, acknowledge injustice, and to enact the potential for ethical dialogue between myself and others. This responsibility gestures to the possibility of border crossing as an ‘act of liberation’ that resides in the acknowledgement of historical injustices and their continued impact on both the beneficiaries and the victims of coloniality in the present.
- Authors: Berger, Karen
- Date: 2021
- Type: Text , Journal article
- Relation: Humanities Vol. 10, no. 4 (2021), p. 112
- Full Text:
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- Description: This paper investigates border-making dynamics in the two political arenas where my subjectivity is most acutely implicated across time—the Jewish Holocaust (as an intergenerational victim) and the Aboriginal genocide (as an unwitting beneficiary). Albeit that there are many differences between the drivers of antisemitism and racism against Indigenous Australians, I investigate both of these racist structures through the lens of border-thinking as theorised by Walter Mignolo as a method of decolonisation (2006). The article has been formatted as an example of discursive border-crossing by juxtaposing theoretical ideas (particularly inspired by Zygmunt Bauman and Deborah Bird Rose) with interjections from my personal journal. I explore my own performative storytelling as a means for me to take responsibility to question power structures, acknowledge injustice, and to enact the potential for ethical dialogue between myself and others. This responsibility gestures to the possibility of border crossing as an ‘act of liberation’ that resides in the acknowledgement of historical injustices and their continued impact on both the beneficiaries and the victims of coloniality in the present.
Physical exercise and health-related quality of life in office workers: A systematic review and meta-analysis
- Nguyen, Thi, Nguyen, Huy, Kim, Jin
- Authors: Nguyen, Thi , Nguyen, Huy , Kim, Jin
- Date: 2021
- Type: Text , Journal article , Review
- Relation: International Journal of Environmental Research and Public Health Vol. 18, no. 7 (2021), p.
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- Description: Office workers are at high risk for many chronic diseases, lowering their health-related quality of life (HRQOL). This systematic review and meta-analysis aimed to summarize the effects of physical exercise on HRQOL in office workers with and without health problems using data obtained from randomized controlled trials (RCTs), quasi-experimental, and observational studies. We searched PubMed, Web of Science, Scopus, Cochrane Library, and several grey literature databases, and identified 26 relevant studies for the synthesis. Overall, physical exercise significantly improved general (standardized mean difference (SMD) = 1.05; 95% confidence interval (CI): 0.66 to 1.44) and mental (SMD = 0.42; 95% CI: 0.19 to 0.66) HRQOL in office workers. Compared with healthy office workers, unhealthy office workers experienced greater improvements in general (unhealthy, SMD = 2.76; 95% CI: 1.63 to 3.89; healthy, SMD = 0.23; 95% CI: −0.09 to 0.56) and physical (unhealthy, SMD = 0.38; 95% CI: 0.17 to 0.58; healthy, SMD = −0.20; 95% CI: −0.51 to 0.11) HRQOL. Unsupervised physical exercise significantly improved general and mental HRQOL, while directly supervised physical exercise significantly improved only general HRQOL. Although physical exercise, especially unsupervised physical exercise, should be encouraged to improve HRQOL in office workers, detailed recommendations could not be made because of the diverse exercise types with different intensities. Therefore, further studies are needed to determine the optimal exercise for office workers with different health conditions. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
- Authors: Nguyen, Thi , Nguyen, Huy , Kim, Jin
- Date: 2021
- Type: Text , Journal article , Review
- Relation: International Journal of Environmental Research and Public Health Vol. 18, no. 7 (2021), p.
- Full Text:
- Reviewed:
- Description: Office workers are at high risk for many chronic diseases, lowering their health-related quality of life (HRQOL). This systematic review and meta-analysis aimed to summarize the effects of physical exercise on HRQOL in office workers with and without health problems using data obtained from randomized controlled trials (RCTs), quasi-experimental, and observational studies. We searched PubMed, Web of Science, Scopus, Cochrane Library, and several grey literature databases, and identified 26 relevant studies for the synthesis. Overall, physical exercise significantly improved general (standardized mean difference (SMD) = 1.05; 95% confidence interval (CI): 0.66 to 1.44) and mental (SMD = 0.42; 95% CI: 0.19 to 0.66) HRQOL in office workers. Compared with healthy office workers, unhealthy office workers experienced greater improvements in general (unhealthy, SMD = 2.76; 95% CI: 1.63 to 3.89; healthy, SMD = 0.23; 95% CI: −0.09 to 0.56) and physical (unhealthy, SMD = 0.38; 95% CI: 0.17 to 0.58; healthy, SMD = −0.20; 95% CI: −0.51 to 0.11) HRQOL. Unsupervised physical exercise significantly improved general and mental HRQOL, while directly supervised physical exercise significantly improved only general HRQOL. Although physical exercise, especially unsupervised physical exercise, should be encouraged to improve HRQOL in office workers, detailed recommendations could not be made because of the diverse exercise types with different intensities. Therefore, further studies are needed to determine the optimal exercise for office workers with different health conditions. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Plasma lipocalin-2/NGAL is stable over 12 weeks and is not modulated by exercise or dieting
- Nakai, Michael, Prestes, Priscilla, O’Brien, Brendan, Charchar, Fadi, Marques, Francine
- Authors: Nakai, Michael , Prestes, Priscilla , O’Brien, Brendan , Charchar, Fadi , Marques, Francine
- Date: 2021
- Type: Text , Journal article
- Relation: Scientific Reports Vol. 11, no. 1 (2021), p.
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- Description: Amongst other immune cells, neutrophils play a key role in systemic inflammation leading to cardiovascular disease and can release inflammatory factors, including lipocalin-2 (LCN2). LCN2 drives cardiac hypertrophy and plays a role in maladaptive remodelling of the heart and has been associated with renal injury. While lifestyle factors such as diet and exercise are known to attenuate low-grade inflammation, their ability to modulate plasma LCN2 levels is unknown. Forty-eight endurance athletes and 52 controls (18–55 years) underwent measurement for various cardiovascular health indicators, along with plasma LCN2 concentration. No significant difference in LCN2 concentration was seen between the two groups. LCN2 was a very weak predictor or absent from models describing blood pressures or predicting athlete status. In another cohort, 57 non-diabetic overweight or obese men and post-menopausal women who fulfilled Adult Treatment Panel III metabolic syndrome criteria were randomly allocated into either a control, modified Dietary Approaches to Stop Hypertension (DASH) diet, or DASH and exercise group. Pre- and post-intervention demographic, cardiovascular health indicators, and plasma LCN2 expression were measured in each individual. While BMI fell in intervention groups, LCN2 levels remained unchanged within and between all groups, as illustrated by strong correlations between LCN2 concentrations pre- and 12 weeks post-intervention (r = 0.743, P < 0.0001). This suggests that circulating LCN2 expression are stable over a period of at least 12 weeks and is not modifiable by diet and exercise. © 2021, The Author(s). *Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Priscilla Prestes, Brendan O'Brien, Fadi Charchar and Francine Marques” is provided in this record** .
- Authors: Nakai, Michael , Prestes, Priscilla , O’Brien, Brendan , Charchar, Fadi , Marques, Francine
- Date: 2021
- Type: Text , Journal article
- Relation: Scientific Reports Vol. 11, no. 1 (2021), p.
- Full Text:
- Reviewed:
- Description: Amongst other immune cells, neutrophils play a key role in systemic inflammation leading to cardiovascular disease and can release inflammatory factors, including lipocalin-2 (LCN2). LCN2 drives cardiac hypertrophy and plays a role in maladaptive remodelling of the heart and has been associated with renal injury. While lifestyle factors such as diet and exercise are known to attenuate low-grade inflammation, their ability to modulate plasma LCN2 levels is unknown. Forty-eight endurance athletes and 52 controls (18–55 years) underwent measurement for various cardiovascular health indicators, along with plasma LCN2 concentration. No significant difference in LCN2 concentration was seen between the two groups. LCN2 was a very weak predictor or absent from models describing blood pressures or predicting athlete status. In another cohort, 57 non-diabetic overweight or obese men and post-menopausal women who fulfilled Adult Treatment Panel III metabolic syndrome criteria were randomly allocated into either a control, modified Dietary Approaches to Stop Hypertension (DASH) diet, or DASH and exercise group. Pre- and post-intervention demographic, cardiovascular health indicators, and plasma LCN2 expression were measured in each individual. While BMI fell in intervention groups, LCN2 levels remained unchanged within and between all groups, as illustrated by strong correlations between LCN2 concentrations pre- and 12 weeks post-intervention (r = 0.743, P < 0.0001). This suggests that circulating LCN2 expression are stable over a period of at least 12 weeks and is not modifiable by diet and exercise. © 2021, The Author(s). *Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Priscilla Prestes, Brendan O'Brien, Fadi Charchar and Francine Marques” is provided in this record** .
Prevalence of and factors associated with anaemia in women of reproductive age in Bangladesh, Maldives and Nepal : evidence from nationally-representative survey data
- Ashfikur Rahman, Md, Sazedur Rahman, Md, Rahman, Muhammad Aziz, Szymlek-Gay, Ewa, Uddin, Riaz, Islam, Sheikh
- Authors: Ashfikur Rahman, Md , Sazedur Rahman, Md , Rahman, Muhammad Aziz , Szymlek-Gay, Ewa , Uddin, Riaz , Islam, Sheikh
- Date: 2021
- Type: Text , Journal article
- Relation: PLoS ONE Vol. 16, no. 1 January (2021), p.
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- Description: Background Anaemia is a significant public health problem in most South-Asian countries, causing increased maternal and child mortality and morbidity. This study aimed to estimate the prevalence of and factors associated with anaemia in women of reproductive age in Bangladesh, Maldives, and Nepal. Methods We used the nationally-representative Demographic and Health Surveys Program data collected from women of reproductive age (15-49 years) in 2011 in Bangladesh (n = 5678), 2016 in Maldives (n = 6837), and 2016 in Nepal (n = 6419). Anaemia was categorized as mild (haemoglobin [Hb] of 10.0-10.9 g/dL for pregnant women and 11.0-11.9 g/dL for non-pregnant women), moderate (Hb of 7.0-9.9 g/dL for pregnant women and 8.0-10.9 g/dL for non-pregnant women), and severe (Hb <7.0 g/dL for pregnant women and <8.0 g/dL for non-pregnant women). Multinomial logistic regression analyses were used to identify factors associated with anaemia. Results The prevalence of anaemia was 41.8% in Bangladesh, 58.5% in Maldives, and 40.6% in Nepal. In Bangladesh, postpartum amenorrhoeic, non-educated, and pregnant women were more likely to have moderate/severe anaemia compared to women who were menopausal, had secondary education, and were not pregnant, respectively. In Maldives, residence in urban areas, underweight, having undergone female sterilization, current pregnancy, and menstruation in the last six weeks were associated with increased odds of moderate/severe anaemia. In Nepal, factors associated with increased odds of moderate/ severe anaemia were having undergone female sterilization and current pregnancy. Conclusion Anaemia remains a significant public health issue among 15-49-year-old women in Bangladesh, Maldives, and Nepal, which requires urgent attention. Effective policies and programmes for the control and prevention of anaemia should take into account the unique factors associated with anaemia identified in each country. In all three countries, strategies for the prevention and control of anaemia should particularly focus on women who are pregnant, underweight, or have undergone sterilization. © 2021 Rahman et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Authors: Ashfikur Rahman, Md , Sazedur Rahman, Md , Rahman, Muhammad Aziz , Szymlek-Gay, Ewa , Uddin, Riaz , Islam, Sheikh
- Date: 2021
- Type: Text , Journal article
- Relation: PLoS ONE Vol. 16, no. 1 January (2021), p.
- Full Text:
- Reviewed:
- Description: Background Anaemia is a significant public health problem in most South-Asian countries, causing increased maternal and child mortality and morbidity. This study aimed to estimate the prevalence of and factors associated with anaemia in women of reproductive age in Bangladesh, Maldives, and Nepal. Methods We used the nationally-representative Demographic and Health Surveys Program data collected from women of reproductive age (15-49 years) in 2011 in Bangladesh (n = 5678), 2016 in Maldives (n = 6837), and 2016 in Nepal (n = 6419). Anaemia was categorized as mild (haemoglobin [Hb] of 10.0-10.9 g/dL for pregnant women and 11.0-11.9 g/dL for non-pregnant women), moderate (Hb of 7.0-9.9 g/dL for pregnant women and 8.0-10.9 g/dL for non-pregnant women), and severe (Hb <7.0 g/dL for pregnant women and <8.0 g/dL for non-pregnant women). Multinomial logistic regression analyses were used to identify factors associated with anaemia. Results The prevalence of anaemia was 41.8% in Bangladesh, 58.5% in Maldives, and 40.6% in Nepal. In Bangladesh, postpartum amenorrhoeic, non-educated, and pregnant women were more likely to have moderate/severe anaemia compared to women who were menopausal, had secondary education, and were not pregnant, respectively. In Maldives, residence in urban areas, underweight, having undergone female sterilization, current pregnancy, and menstruation in the last six weeks were associated with increased odds of moderate/severe anaemia. In Nepal, factors associated with increased odds of moderate/ severe anaemia were having undergone female sterilization and current pregnancy. Conclusion Anaemia remains a significant public health issue among 15-49-year-old women in Bangladesh, Maldives, and Nepal, which requires urgent attention. Effective policies and programmes for the control and prevention of anaemia should take into account the unique factors associated with anaemia identified in each country. In all three countries, strategies for the prevention and control of anaemia should particularly focus on women who are pregnant, underweight, or have undergone sterilization. © 2021 Rahman et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Psychological distress, fear and coping among Malaysians during the COVID-19 pandemic
- Moni, Ahmed, Abdullah, Shalimar, Salehin, Masudus, Cross, Wendy, Rahman, Muhammad Aziz
- Authors: Moni, Ahmed , Abdullah, Shalimar , Salehin, Masudus , Cross, Wendy , Rahman, Muhammad Aziz
- Date: 2021
- Type: Text , Journal article
- Relation: PLoS ONE Vol. 16, no. 9 (2021), p.
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- Description: Introduction The COVID-19 pandemic has enormously affected the psychological well-being, social and working life of millions of people across the world. This study aimed to investigate the psychological distress, fear and coping strategies as a result of the COVID-19 pandemic and its associated factors among Malaysian residents. Methods Participants were invited to an online cross-sectional survey from Aug-Sep 2020. The study assessed psychological distress using the Kessler Psychological Distress Scale, level of fear using the Fear of COVID-19 Scale, and coping strategies using the Brief Resilient Coping Scale. Univariate and multivariate logistic regression analyses were conducted to adjust for potential confounders. Results The mean age (±SD) of the participants (N = 720) was 31.7 (±11.5) years, and most of them were females (67.1%). Half of the participants had an income source, while 216 (30%) identified themselves as frontline health or essential service workers. People whose financial situation was impacted due to COVID-19 (AOR 2.16, 95% CIs 1.54 3.03), people who drank alcohol in the last four weeks (3.43, 1.45 8.10), people who were a patient (2.02, 1.39 2.93), and had higher levels of fear of COVID-19 (2.55, 1.70 3.80) were more likely to have higher levels of psychological distress. Participants who self-isolated due to exposure to COVID-19 (3.12, 1.04 9.32) and who had moderate to very high levels of psychological distress (2.56, 1.71 3.83) had higher levels of fear. Participants who provided care to a family member/patient with a suspected case of COVID-19 were more likely to be moderately to highly resilient compared to those who did not. Conclusion Vulnerable groups of individuals such as patients and those impacted financially during COVID-19 should be supported for their mental wellbeing. Behavioural interventions should be targeted to reduce the impact of alcohol drinking during such crisis period. © 2021 Public Library of Science. All rights reserved. **Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Masudus Salehin, Wendy Cross, Muhammad Aziz Rahman” is provided in this record**
- Authors: Moni, Ahmed , Abdullah, Shalimar , Salehin, Masudus , Cross, Wendy , Rahman, Muhammad Aziz
- Date: 2021
- Type: Text , Journal article
- Relation: PLoS ONE Vol. 16, no. 9 (2021), p.
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- Description: Introduction The COVID-19 pandemic has enormously affected the psychological well-being, social and working life of millions of people across the world. This study aimed to investigate the psychological distress, fear and coping strategies as a result of the COVID-19 pandemic and its associated factors among Malaysian residents. Methods Participants were invited to an online cross-sectional survey from Aug-Sep 2020. The study assessed psychological distress using the Kessler Psychological Distress Scale, level of fear using the Fear of COVID-19 Scale, and coping strategies using the Brief Resilient Coping Scale. Univariate and multivariate logistic regression analyses were conducted to adjust for potential confounders. Results The mean age (±SD) of the participants (N = 720) was 31.7 (±11.5) years, and most of them were females (67.1%). Half of the participants had an income source, while 216 (30%) identified themselves as frontline health or essential service workers. People whose financial situation was impacted due to COVID-19 (AOR 2.16, 95% CIs 1.54 3.03), people who drank alcohol in the last four weeks (3.43, 1.45 8.10), people who were a patient (2.02, 1.39 2.93), and had higher levels of fear of COVID-19 (2.55, 1.70 3.80) were more likely to have higher levels of psychological distress. Participants who self-isolated due to exposure to COVID-19 (3.12, 1.04 9.32) and who had moderate to very high levels of psychological distress (2.56, 1.71 3.83) had higher levels of fear. Participants who provided care to a family member/patient with a suspected case of COVID-19 were more likely to be moderately to highly resilient compared to those who did not. Conclusion Vulnerable groups of individuals such as patients and those impacted financially during COVID-19 should be supported for their mental wellbeing. Behavioural interventions should be targeted to reduce the impact of alcohol drinking during such crisis period. © 2021 Public Library of Science. All rights reserved. **Please note that there are multiple authors for this article therefore only the name of the first 5 including Federation University Australia affiliate “Masudus Salehin, Wendy Cross, Muhammad Aziz Rahman” is provided in this record**
Reduced renal function may explain the higher prevalence of hyperuricemia in older people
- Wang, Yutang, Zhang, Wanlin, Qian, Tingting, Sun, Hui, Xu, Qun, Hou, Xujuan, Hu, Wenqi, Zhang, Guang, Drummond, Grant, Sobey, Chris, Charchar, Fadi, Golledge, Jonathan, Yang, Guang
- Authors: Wang, Yutang , Zhang, Wanlin , Qian, Tingting , Sun, Hui , Xu, Qun , Hou, Xujuan , Hu, Wenqi , Zhang, Guang , Drummond, Grant , Sobey, Chris , Charchar, Fadi , Golledge, Jonathan , Yang, Guang
- Date: 2021
- Type: Text , Journal article
- Relation: Scientific Reports Vol. 11, no. 1 (2021), p.
- Relation: https://purl.org/au-research/grants/nhmrc/1062671
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- Description: This study aimed to investigate the contribution of renal dysfunction to enhanced hyperuricemia prevalence in older people. A cohort of 13,288 Chinese people aged between 40 and 95 years were recruited from January to May 2019. Serum uric acid concentration and estimated glomerular filtration rate [eGFR] were measured. The associations between age or eGFR and serum uric acid or hyperuricemia were analyzed using linear or binary logistic regression adjusting for risk factors. Uric acid concentration and prevalence of hyperuricemia were greater in older participants. Adjustment for reduced renal function (eGFR < 60 mL/min/1.73 m2) eliminated the associations between older age and higher uric acid concentration and between older age and higher prevalence of hyperuricemia diagnosis, whereas adjustment for other risk factors did not change those associations. Lower eGFR was associated with higher uric acid concentration both before (β = − 0.296, P < 0.001) and after adjustment for age (β = − 0.313, P < 0.001). Reduced renal function was associated with hyperuricemia diagnosis both before (odds ratio, OR, 3.64; 95% CI 3.10–4.28; P < 0.001) and after adjustment for age (adjusted OR, 3.82; 95% CI 3.22–4.54; P < 0.001). Mean serum uric acid and prevalence of hyperuricemia were higher in people with eGFR < 60 mL/min/1.73 m2 than those with eGFR ≥ 60 mL/min/1.73 m2. The prevalence of reduced renal function increased with older age (P < 0.001). This study suggests that reduced renal function can explain the increased uric acid levels and hyperuricemia diagnoses in older people. © 2021, The Author(s).
- Authors: Wang, Yutang , Zhang, Wanlin , Qian, Tingting , Sun, Hui , Xu, Qun , Hou, Xujuan , Hu, Wenqi , Zhang, Guang , Drummond, Grant , Sobey, Chris , Charchar, Fadi , Golledge, Jonathan , Yang, Guang
- Date: 2021
- Type: Text , Journal article
- Relation: Scientific Reports Vol. 11, no. 1 (2021), p.
- Relation: https://purl.org/au-research/grants/nhmrc/1062671
- Full Text:
- Reviewed:
- Description: This study aimed to investigate the contribution of renal dysfunction to enhanced hyperuricemia prevalence in older people. A cohort of 13,288 Chinese people aged between 40 and 95 years were recruited from January to May 2019. Serum uric acid concentration and estimated glomerular filtration rate [eGFR] were measured. The associations between age or eGFR and serum uric acid or hyperuricemia were analyzed using linear or binary logistic regression adjusting for risk factors. Uric acid concentration and prevalence of hyperuricemia were greater in older participants. Adjustment for reduced renal function (eGFR < 60 mL/min/1.73 m2) eliminated the associations between older age and higher uric acid concentration and between older age and higher prevalence of hyperuricemia diagnosis, whereas adjustment for other risk factors did not change those associations. Lower eGFR was associated with higher uric acid concentration both before (β = − 0.296, P < 0.001) and after adjustment for age (β = − 0.313, P < 0.001). Reduced renal function was associated with hyperuricemia diagnosis both before (odds ratio, OR, 3.64; 95% CI 3.10–4.28; P < 0.001) and after adjustment for age (adjusted OR, 3.82; 95% CI 3.22–4.54; P < 0.001). Mean serum uric acid and prevalence of hyperuricemia were higher in people with eGFR < 60 mL/min/1.73 m2 than those with eGFR ≥ 60 mL/min/1.73 m2. The prevalence of reduced renal function increased with older age (P < 0.001). This study suggests that reduced renal function can explain the increased uric acid levels and hyperuricemia diagnoses in older people. © 2021, The Author(s).