Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c
- Zhou, Bin, Sheffer, Kate, Bennett, James, Gregg, Edward, Danaei, Goodarz, Singleton, Rosie, Shaw, Jonathan, Mishra, Anu, Lhoste, Victor, Carrillo-Larco, Rodrigo, Kengne, Andre, Phelps, Nowell, Heap, Rachel, Rayner, Archie, Stevens, Gretchen, Paciorek, Chris, Riley, Leanne, Cowan, Melanie, Savin, Stefan, Vander Hoorn, Stephen, Lu, Yuan, Pavkov, Meda, Imperatore, Giuseppina, Aguilar-Salinas, Carlos, Ahmad, Noor, Anjana, Ranjit, Davletov, Kairat, Farzadfar, Farshad, González-Villalpando, Clicerio, Charchar, Fadi
- Authors: Zhou, Bin , Sheffer, Kate , Bennett, James , Gregg, Edward , Danaei, Goodarz , Singleton, Rosie , Shaw, Jonathan , Mishra, Anu , Lhoste, Victor , Carrillo-Larco, Rodrigo , Kengne, Andre , Phelps, Nowell , Heap, Rachel , Rayner, Archie , Stevens, Gretchen , Paciorek, Chris , Riley, Leanne , Cowan, Melanie , Savin, Stefan , Vander Hoorn, Stephen , Lu, Yuan , Pavkov, Meda , Imperatore, Giuseppina , Aguilar-Salinas, Carlos , Ahmad, Noor , Anjana, Ranjit , Davletov, Kairat , Farzadfar, Farshad , González-Villalpando, Clicerio , Charchar, Fadi
- Date: 2023
- Type: Text , Journal article
- Relation: Nature Medicine Vol. 29, no. 11 (2023), p. 2885-2901
- Full Text:
- Reviewed:
- Description: Fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) are both used to diagnose diabetes, but these measurements can identify different people as having diabetes. We used data from 117 population-based studies and quantified, in different world regions, the prevalence of diagnosed diabetes, and whether those who were previously undiagnosed and detected as having diabetes in survey screening, had elevated FPG, HbA1c or both. We developed prediction equations for estimating the probability that a person without previously diagnosed diabetes, and at a specific level of FPG, had elevated HbA1c, and vice versa. The age-standardized proportion of diabetes that was previously undiagnosed and detected in survey screening ranged from 30% in the high-income western region to 66% in south Asia. Among those with screen-detected diabetes with either test, the age-standardized proportion who had elevated levels of both FPG and HbA1c was 29–39% across regions; the remainder had discordant elevation of FPG or HbA1c. In most low- and middle-income regions, isolated elevated HbA1c was more common than isolated elevated FPG. In these regions, the use of FPG alone may delay diabetes diagnosis and underestimate diabetes prevalence. Our prediction equations help allocate finite resources for measuring HbA1c to reduce the global shortfall in diabetes diagnosis and surveillance. © 2023, The Author(s). **Please note that there are multiple authors for this article therefore only the name of the first 30 including Federation University Australia affiliate “Fadi Charchar" is provided in this record**
- Authors: Zhou, Bin , Sheffer, Kate , Bennett, James , Gregg, Edward , Danaei, Goodarz , Singleton, Rosie , Shaw, Jonathan , Mishra, Anu , Lhoste, Victor , Carrillo-Larco, Rodrigo , Kengne, Andre , Phelps, Nowell , Heap, Rachel , Rayner, Archie , Stevens, Gretchen , Paciorek, Chris , Riley, Leanne , Cowan, Melanie , Savin, Stefan , Vander Hoorn, Stephen , Lu, Yuan , Pavkov, Meda , Imperatore, Giuseppina , Aguilar-Salinas, Carlos , Ahmad, Noor , Anjana, Ranjit , Davletov, Kairat , Farzadfar, Farshad , González-Villalpando, Clicerio , Charchar, Fadi
- Date: 2023
- Type: Text , Journal article
- Relation: Nature Medicine Vol. 29, no. 11 (2023), p. 2885-2901
- Full Text:
- Reviewed:
- Description: Fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) are both used to diagnose diabetes, but these measurements can identify different people as having diabetes. We used data from 117 population-based studies and quantified, in different world regions, the prevalence of diagnosed diabetes, and whether those who were previously undiagnosed and detected as having diabetes in survey screening, had elevated FPG, HbA1c or both. We developed prediction equations for estimating the probability that a person without previously diagnosed diabetes, and at a specific level of FPG, had elevated HbA1c, and vice versa. The age-standardized proportion of diabetes that was previously undiagnosed and detected in survey screening ranged from 30% in the high-income western region to 66% in south Asia. Among those with screen-detected diabetes with either test, the age-standardized proportion who had elevated levels of both FPG and HbA1c was 29–39% across regions; the remainder had discordant elevation of FPG or HbA1c. In most low- and middle-income regions, isolated elevated HbA1c was more common than isolated elevated FPG. In these regions, the use of FPG alone may delay diabetes diagnosis and underestimate diabetes prevalence. Our prediction equations help allocate finite resources for measuring HbA1c to reduce the global shortfall in diabetes diagnosis and surveillance. © 2023, The Author(s). **Please note that there are multiple authors for this article therefore only the name of the first 30 including Federation University Australia affiliate “Fadi Charchar" is provided in this record**
Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021
- Ong, Kanyin, Stafford, Lauryn, McLaughlin, Susan, Boyko, Edward, Vollset, Stein, Smith, Amanda, Dalton, Bronte, Duprey, Joe, Cruz, Jessica, Hagins, Hailey, Lindstedt, Paulina, Aali, Amirali, Abate, Yohannes, Abate, Melew, Abbasian, Mohammadreza, Abbasi-Kangevari, Zeinab, Abbasi-Kangevari, Mohsen, ElHafeez, Samar, Abd-Rabu, Rami, Abdulah, Deldar, Abdullah, Abu, Abedi, Vida, Abidi, Hassan, Aboagye, Richard, Abolhassani, Hassan, Abu-Gharbieh, Eshetie, Abu-Zaid, Ahmed, Adane, Tigist, Adane, Denberu, Rahman, Muhammad Aziz
- Authors: Ong, Kanyin , Stafford, Lauryn , McLaughlin, Susan , Boyko, Edward , Vollset, Stein , Smith, Amanda , Dalton, Bronte , Duprey, Joe , Cruz, Jessica , Hagins, Hailey , Lindstedt, Paulina , Aali, Amirali , Abate, Yohannes , Abate, Melew , Abbasian, Mohammadreza , Abbasi-Kangevari, Zeinab , Abbasi-Kangevari, Mohsen , ElHafeez, Samar , Abd-Rabu, Rami , Abdulah, Deldar , Abdullah, Abu , Abedi, Vida , Abidi, Hassan , Aboagye, Richard , Abolhassani, Hassan , Abu-Gharbieh, Eshetie , Abu-Zaid, Ahmed , Adane, Tigist , Adane, Denberu , Rahman, Muhammad Aziz
- Date: 2023
- Type: Text , Journal article
- Relation: The Lancet Vol. 402, no. 10397 (2023), p. 203-234
- Full Text:
- Reviewed:
- Description: Background: Diabetes is one of the leading causes of death and disability worldwide, and affects people regardless of country, age group, or sex. Using the most recent evidentiary and analytical framework from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD), we produced location-specific, age-specific, and sex-specific estimates of diabetes prevalence and burden from 1990 to 2021, the proportion of type 1 and type 2 diabetes in 2021, the proportion of the type 2 diabetes burden attributable to selected risk factors, and projections of diabetes prevalence through 2050. Methods: Estimates of diabetes prevalence and burden were computed in 204 countries and territories, across 25 age groups, for males and females separately and combined; these estimates comprised lost years of healthy life, measured in disability-adjusted life-years (DALYs; defined as the sum of years of life lost [YLLs] and years lived with disability [YLDs]). We used the Cause of Death Ensemble model (CODEm) approach to estimate deaths due to diabetes, incorporating 25 666 location-years of data from vital registration and verbal autopsy reports in separate total (including both type 1 and type 2 diabetes) and type-specific models. Other forms of diabetes, including gestational and monogenic diabetes, were not explicitly modelled. Total and type 1 diabetes prevalence was estimated by use of a Bayesian meta-regression modelling tool, DisMod-MR 2.1, to analyse 1527 location-years of data from the scientific literature, survey microdata, and insurance claims; type 2 diabetes estimates were computed by subtracting type 1 diabetes from total estimates. Mortality and prevalence estimates, along with standard life expectancy and disability weights, were used to calculate YLLs, YLDs, and DALYs. When appropriate, we extrapolated estimates to a hypothetical population with a standardised age structure to allow comparison in populations with different age structures. We used the comparative risk assessment framework to estimate the risk-attributable type 2 diabetes burden for 16 risk factors falling under risk categories including environmental and occupational factors, tobacco use, high alcohol use, high body-mass index (BMI), dietary factors, and low physical activity. Using a regression framework, we forecast type 1 and type 2 diabetes prevalence through 2050 with Socio-demographic Index (SDI) and high BMI as predictors, respectively. Findings: In 2021, there were 529 million (95% uncertainty interval [UI] 500–564) people living with diabetes worldwide, and the global age-standardised total diabetes prevalence was 6·1% (5·8–6·5). At the super-region level, the highest age-standardised rates were observed in north Africa and the Middle East (9·3% [8·7–9·9]) and, at the regional level, in Oceania (12·3% [11·5–13·0]). Nationally, Qatar had the world's highest age-specific prevalence of diabetes, at 76·1% (73·1–79·5) in individuals aged 75–79 years. Total diabetes prevalence—especially among older adults—primarily reflects type 2 diabetes, which in 2021 accounted for 96·0% (95·1–96·8) of diabetes cases and 95·4% (94·9–95·9) of diabetes DALYs worldwide. In 2021, 52·2% (25·5–71·8) of global type 2 diabetes DALYs were attributable to high BMI. The contribution of high BMI to type 2 diabetes DALYs rose by 24·3% (18·5–30·4) worldwide between 1990 and 2021. By 2050, more than 1·31 billion (1·22–1·39) people are projected to have diabetes, with expected age-standardised total diabetes prevalence rates greater than 10% in two super-regions: 16·8% (16·1–17·6) in north Africa and the Middle East and 11·3% (10·8–11·9) in Latin America and Caribbean. By 2050, 89 (43·6%) of 204 countries and territories will have an age-standardised rate greater than 10%. Interpretation: Diabetes remains a substantial public health issue. Type 2 diabetes, which makes up the bulk of diabetes cases, is largely preventable and, in some cases, potentially reversible if identified and managed early in the disea e course. However, all evidence indicates that diabetes prevalence is increasing worldwide, primarily due to a rise in obesity caused by multiple factors. Preventing and controlling type 2 diabetes remains an ongoing challenge. It is essential to better understand disparities in risk factor profiles and diabetes burden across populations, to inform strategies to successfully control diabetes risk factors within the context of multiple and complex drivers. Funding: Bill & Melinda Gates Foundation. © 2023 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license. **Please note that there are multiple authors for this article therefore only the name of the first 30 including Federation University Australia affiliate “Muhammad Aziz Rahman” is provided in this record**
- Authors: Ong, Kanyin , Stafford, Lauryn , McLaughlin, Susan , Boyko, Edward , Vollset, Stein , Smith, Amanda , Dalton, Bronte , Duprey, Joe , Cruz, Jessica , Hagins, Hailey , Lindstedt, Paulina , Aali, Amirali , Abate, Yohannes , Abate, Melew , Abbasian, Mohammadreza , Abbasi-Kangevari, Zeinab , Abbasi-Kangevari, Mohsen , ElHafeez, Samar , Abd-Rabu, Rami , Abdulah, Deldar , Abdullah, Abu , Abedi, Vida , Abidi, Hassan , Aboagye, Richard , Abolhassani, Hassan , Abu-Gharbieh, Eshetie , Abu-Zaid, Ahmed , Adane, Tigist , Adane, Denberu , Rahman, Muhammad Aziz
- Date: 2023
- Type: Text , Journal article
- Relation: The Lancet Vol. 402, no. 10397 (2023), p. 203-234
- Full Text:
- Reviewed:
- Description: Background: Diabetes is one of the leading causes of death and disability worldwide, and affects people regardless of country, age group, or sex. Using the most recent evidentiary and analytical framework from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD), we produced location-specific, age-specific, and sex-specific estimates of diabetes prevalence and burden from 1990 to 2021, the proportion of type 1 and type 2 diabetes in 2021, the proportion of the type 2 diabetes burden attributable to selected risk factors, and projections of diabetes prevalence through 2050. Methods: Estimates of diabetes prevalence and burden were computed in 204 countries and territories, across 25 age groups, for males and females separately and combined; these estimates comprised lost years of healthy life, measured in disability-adjusted life-years (DALYs; defined as the sum of years of life lost [YLLs] and years lived with disability [YLDs]). We used the Cause of Death Ensemble model (CODEm) approach to estimate deaths due to diabetes, incorporating 25 666 location-years of data from vital registration and verbal autopsy reports in separate total (including both type 1 and type 2 diabetes) and type-specific models. Other forms of diabetes, including gestational and monogenic diabetes, were not explicitly modelled. Total and type 1 diabetes prevalence was estimated by use of a Bayesian meta-regression modelling tool, DisMod-MR 2.1, to analyse 1527 location-years of data from the scientific literature, survey microdata, and insurance claims; type 2 diabetes estimates were computed by subtracting type 1 diabetes from total estimates. Mortality and prevalence estimates, along with standard life expectancy and disability weights, were used to calculate YLLs, YLDs, and DALYs. When appropriate, we extrapolated estimates to a hypothetical population with a standardised age structure to allow comparison in populations with different age structures. We used the comparative risk assessment framework to estimate the risk-attributable type 2 diabetes burden for 16 risk factors falling under risk categories including environmental and occupational factors, tobacco use, high alcohol use, high body-mass index (BMI), dietary factors, and low physical activity. Using a regression framework, we forecast type 1 and type 2 diabetes prevalence through 2050 with Socio-demographic Index (SDI) and high BMI as predictors, respectively. Findings: In 2021, there were 529 million (95% uncertainty interval [UI] 500–564) people living with diabetes worldwide, and the global age-standardised total diabetes prevalence was 6·1% (5·8–6·5). At the super-region level, the highest age-standardised rates were observed in north Africa and the Middle East (9·3% [8·7–9·9]) and, at the regional level, in Oceania (12·3% [11·5–13·0]). Nationally, Qatar had the world's highest age-specific prevalence of diabetes, at 76·1% (73·1–79·5) in individuals aged 75–79 years. Total diabetes prevalence—especially among older adults—primarily reflects type 2 diabetes, which in 2021 accounted for 96·0% (95·1–96·8) of diabetes cases and 95·4% (94·9–95·9) of diabetes DALYs worldwide. In 2021, 52·2% (25·5–71·8) of global type 2 diabetes DALYs were attributable to high BMI. The contribution of high BMI to type 2 diabetes DALYs rose by 24·3% (18·5–30·4) worldwide between 1990 and 2021. By 2050, more than 1·31 billion (1·22–1·39) people are projected to have diabetes, with expected age-standardised total diabetes prevalence rates greater than 10% in two super-regions: 16·8% (16·1–17·6) in north Africa and the Middle East and 11·3% (10·8–11·9) in Latin America and Caribbean. By 2050, 89 (43·6%) of 204 countries and territories will have an age-standardised rate greater than 10%. Interpretation: Diabetes remains a substantial public health issue. Type 2 diabetes, which makes up the bulk of diabetes cases, is largely preventable and, in some cases, potentially reversible if identified and managed early in the disea e course. However, all evidence indicates that diabetes prevalence is increasing worldwide, primarily due to a rise in obesity caused by multiple factors. Preventing and controlling type 2 diabetes remains an ongoing challenge. It is essential to better understand disparities in risk factor profiles and diabetes burden across populations, to inform strategies to successfully control diabetes risk factors within the context of multiple and complex drivers. Funding: Bill & Melinda Gates Foundation. © 2023 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license. **Please note that there are multiple authors for this article therefore only the name of the first 30 including Federation University Australia affiliate “Muhammad Aziz Rahman” is provided in this record**
Global, regional, and national incidence of six major immune-mediated inflammatory diseases: findings from the global burden of disease study 2019
- Wu, Dongze, Jin, Yingzhao, Xing, Yuhan, Abate, Melsew, Abbasian, Mohammadreza, Abbasi-Kangevari, Mohsen, Abbasi-Kangevari, Zeinab, Abd-Allah, Foad, Abdelmasseh, Michael, Abdollahifar, Mohammad-Amin, Abdulah, Deldar, Abedi, Aidin, Abedi, Vida, Abidi, Hassan, Aboagye, Richard, Abolhassani, Hassan, Abuabara, Katrina, Abyadeh, Morteza, Addo, Isaac, Adeniji, Kayode, Adepoju, Abiola, Adesina, Miracle, Adnani, Qorinah, Afarideh, Mohsen, Aghamiri, Shahin, Agodi, Antonella, Agrawal, Anurag, Arriagada, Constanza, Ahmad, Antonella, Rahman, Muhammad Aziz
- Authors: Wu, Dongze , Jin, Yingzhao , Xing, Yuhan , Abate, Melsew , Abbasian, Mohammadreza , Abbasi-Kangevari, Mohsen , Abbasi-Kangevari, Zeinab , Abd-Allah, Foad , Abdelmasseh, Michael , Abdollahifar, Mohammad-Amin , Abdulah, Deldar , Abedi, Aidin , Abedi, Vida , Abidi, Hassan , Aboagye, Richard , Abolhassani, Hassan , Abuabara, Katrina , Abyadeh, Morteza , Addo, Isaac , Adeniji, Kayode , Adepoju, Abiola , Adesina, Miracle , Adnani, Qorinah , Afarideh, Mohsen , Aghamiri, Shahin , Agodi, Antonella , Agrawal, Anurag , Arriagada, Constanza , Ahmad, Antonella , Rahman, Muhammad Aziz
- Date: 2023
- Type: Text , Journal article
- Relation: eClinicalMedicine Vol. 64, no. (2023), p.
- Full Text:
- Reviewed:
- Description: Background: The causes for immune-mediated inflammatory diseases (IMIDs) are diverse and the incidence trends of IMIDs from specific causes are rarely studied. The study aims to investigate the pattern and trend of IMIDs from 1990 to 2019. Methods: We collected detailed information on six major causes of IMIDs, including asthma, inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis, psoriasis, and atopic dermatitis, between 1990 and 2019, derived from the Global Burden of Disease study in 2019. The average annual percent change (AAPC) in number of incidents and age standardized incidence rate (ASR) on IMIDs, by sex, age, region, and causes, were calculated to quantify the temporal trends. Findings: In 2019, rheumatoid arthritis, atopic dermatitis, asthma, multiple sclerosis, psoriasis, inflammatory bowel disease accounted 1.59%, 36.17%, 54.71%, 0.09%, 6.84%, 0.60% of overall new IMIDs cases, respectively. The ASR of IMIDs showed substantial regional and global variation with the highest in High SDI region, High-income North America, and United States of America. Throughout human lifespan, the age distribution of incident cases from six IMIDs was quite different. Globally, incident cases of IMIDs increased with an AAPC of 0.68 and the ASR decreased with an AAPC of
- Authors: Wu, Dongze , Jin, Yingzhao , Xing, Yuhan , Abate, Melsew , Abbasian, Mohammadreza , Abbasi-Kangevari, Mohsen , Abbasi-Kangevari, Zeinab , Abd-Allah, Foad , Abdelmasseh, Michael , Abdollahifar, Mohammad-Amin , Abdulah, Deldar , Abedi, Aidin , Abedi, Vida , Abidi, Hassan , Aboagye, Richard , Abolhassani, Hassan , Abuabara, Katrina , Abyadeh, Morteza , Addo, Isaac , Adeniji, Kayode , Adepoju, Abiola , Adesina, Miracle , Adnani, Qorinah , Afarideh, Mohsen , Aghamiri, Shahin , Agodi, Antonella , Agrawal, Anurag , Arriagada, Constanza , Ahmad, Antonella , Rahman, Muhammad Aziz
- Date: 2023
- Type: Text , Journal article
- Relation: eClinicalMedicine Vol. 64, no. (2023), p.
- Full Text:
- Reviewed:
- Description: Background: The causes for immune-mediated inflammatory diseases (IMIDs) are diverse and the incidence trends of IMIDs from specific causes are rarely studied. The study aims to investigate the pattern and trend of IMIDs from 1990 to 2019. Methods: We collected detailed information on six major causes of IMIDs, including asthma, inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis, psoriasis, and atopic dermatitis, between 1990 and 2019, derived from the Global Burden of Disease study in 2019. The average annual percent change (AAPC) in number of incidents and age standardized incidence rate (ASR) on IMIDs, by sex, age, region, and causes, were calculated to quantify the temporal trends. Findings: In 2019, rheumatoid arthritis, atopic dermatitis, asthma, multiple sclerosis, psoriasis, inflammatory bowel disease accounted 1.59%, 36.17%, 54.71%, 0.09%, 6.84%, 0.60% of overall new IMIDs cases, respectively. The ASR of IMIDs showed substantial regional and global variation with the highest in High SDI region, High-income North America, and United States of America. Throughout human lifespan, the age distribution of incident cases from six IMIDs was quite different. Globally, incident cases of IMIDs increased with an AAPC of 0.68 and the ASR decreased with an AAPC of
Graph learning for anomaly analytics : algorithms, applications, and challenges
- Ren, Jing, Xia, Feng, Lee, Ivan, Noori Hoshyar, Azadeh, Aggarwal, Charu
- Authors: Ren, Jing , Xia, Feng , Lee, Ivan , Noori Hoshyar, Azadeh , Aggarwal, Charu
- Date: 2023
- Type: Text , Journal article
- Relation: ACM Transactions on Intelligent Systems and Technology Vol. 14, no. 2 (2023), p.
- Full Text:
- Reviewed:
- Description: Anomaly analytics is a popular and vital task in various research contexts that has been studied for several decades. At the same time, deep learning has shown its capacity in solving many graph-based tasks, like node classification, link prediction, and graph classification. Recently, many studies are extending graph learning models for solving anomaly analytics problems, resulting in beneficial advances in graph-based anomaly analytics techniques. In this survey, we provide a comprehensive overview of graph learning methods for anomaly analytics tasks. We classify them into four categories based on their model architectures, namely graph convolutional network, graph attention network, graph autoencoder, and other graph learning models. The differences between these methods are also compared in a systematic manner. Furthermore, we outline several graph-based anomaly analytics applications across various domains in the real world. Finally, we discuss five potential future research directions in this rapidly growing field. © 2023 Association for Computing Machinery.
- Authors: Ren, Jing , Xia, Feng , Lee, Ivan , Noori Hoshyar, Azadeh , Aggarwal, Charu
- Date: 2023
- Type: Text , Journal article
- Relation: ACM Transactions on Intelligent Systems and Technology Vol. 14, no. 2 (2023), p.
- Full Text:
- Reviewed:
- Description: Anomaly analytics is a popular and vital task in various research contexts that has been studied for several decades. At the same time, deep learning has shown its capacity in solving many graph-based tasks, like node classification, link prediction, and graph classification. Recently, many studies are extending graph learning models for solving anomaly analytics problems, resulting in beneficial advances in graph-based anomaly analytics techniques. In this survey, we provide a comprehensive overview of graph learning methods for anomaly analytics tasks. We classify them into four categories based on their model architectures, namely graph convolutional network, graph attention network, graph autoencoder, and other graph learning models. The differences between these methods are also compared in a systematic manner. Furthermore, we outline several graph-based anomaly analytics applications across various domains in the real world. Finally, we discuss five potential future research directions in this rapidly growing field. © 2023 Association for Computing Machinery.
Graph lifelong learning : a survey
- Febrinanto, Falih, Xia, Feng, Moore, Kristen, Thapa, Chandra, Aggarwal, Charu
- Authors: Febrinanto, Falih , Xia, Feng , Moore, Kristen , Thapa, Chandra , Aggarwal, Charu
- Date: 2023
- Type: Text , Journal article
- Relation: IEEE Computational Intelligence Magazine Vol. 18, no. 1 (2023), p. 32-51
- Full Text: false
- Reviewed:
- Description: Graph learning is a popular approach for perfor ming machine learning on graph-structured data. It has revolutionized the machine learning ability to model graph data to address downstream tasks. Its application is wide due to the availability of graph data ranging from all types of networks to information systems. Most graph learning methods assume that the graph is static and its complete structure is known during training. This limits their applicability since they cannot be applied to problems where the underlying graph grows over time and/or new tasks emerge incrementally. Such applications require a lifelong learning approach that can learn the graph continuously and accommodate new information whilst retaining previously learned knowledge. Lifelong learning methods that enable continuous learning in regular domains like images and text cannot be directly applied to continuously evolving graph data, due to its irregular structure. As a result, graph lifelong learning is gaining attention from the research community. This survey paper provides a comprehensive overview of recent advancements in graph lifelong learning, including the categorization of existing methods, and the discussions of potential applications and open research problems. © 2005-2012 IEEE.
- Wang, Kaixin, Yang, Yong, Fan, Mingdi, Tang, Yuhang, Li, Haoyang, Chen, Rong, Hu, Jiefeng, Zeng, Weibo, Rodriguez, Jose
- Authors: Wang, Kaixin , Yang, Yong , Fan, Mingdi , Tang, Yuhang , Li, Haoyang , Chen, Rong , Hu, Jiefeng , Zeng, Weibo , Rodriguez, Jose
- Date: 2023
- Type: Text , Journal article
- Relation: IEEE Transactions on Power Electronics Vol. 38, no. 2 (2023), p. 2408-2420
- Full Text: false
- Reviewed:
- Description: This article proposes a new grid impedance detection method incorporating the complex coefficient filter (CCF) with full-order capacitor current observer for a T-type three-level grid-connected inverter controlled by the inverter output current feedback. Compared with conventional CCF impedance detection algorithms, the proposed method reduces the number of current sensors and detects the grid impedance accurately. First, based on the sampled inverter output current and grid-connected voltage signals, the grid-connected current is estimated. Then, the CCF method is used to extract harmonics from the grid-connected current and voltage signals to calculate the grid impedance. Finally, the correctness of the full-order capacitor current observer is verified by simulation and the feasibility and effectiveness of the proposed algorithm are verified experimentally based on a laboratory prototype. © 1986-2012 IEEE.
Healing, faith and fear : church opening in the United States during COVID-19 restrictions
- Smith, Naomi, Snider, Anne-Marie
- Authors: Smith, Naomi , Snider, Anne-Marie
- Date: 2023
- Type: Text , Journal article
- Relation: Journal of Contemporary Religion Vol. 38, no. 2 (2023), p. 283-304
- Full Text: false
- Reviewed:
- Description: This article examines how resistance to stay-at-home orders was framed to congregants through sermons and in statements to media outlets. Using an approach informed by grounded theory, we analysed news articles of church behaviour and the YouTube videos of sermons from pastors that protested against COVID-19 guidelines from March 2020 to November 2020. We also draw on legal filings to identify churches that most actively resisted closures. In analysing these publicly available data, a relationship between church openings in the United States and an evangelical theology of resistance particular to non-denominational churches to public health efforts emerged. Our analysis found that ‘largely evangelical’ churches that are not considered part of a mainline evangelical denomination were more likely to seek ways to remain open in defiance of public health orders. We use the terms ‘largely evangelical’ and ‘mainline evangelical’ to distinguish these two very different denominational families. Evidence from this article suggests that evangelical Christian churches in the US that are not considered ‘mainline evangelical’ denominations (e.g. non-denominational, Pentecostal) were more likely to resist stay-at-home orders and more prepared to be legally active in resisting such policies and gather indoors (as opposed to Catholic churches and ‘mainline evangelical’ denominations). © 2023 Informa UK Limited, trading as Taylor & Francis Group.
Health literacy among children living with a long-term condition : ‘what I know and who I tell’
- Peck, Blake, Bray, Lucy, Dickinson, Annette, Blamires, Julie, Terry, Daniel, Carter, Bernie
- Authors: Peck, Blake , Bray, Lucy , Dickinson, Annette , Blamires, Julie , Terry, Daniel , Carter, Bernie
- Date: 2023
- Type: Text , Journal article
- Relation: Health Education Journal Vol. 82, no. 5 (2023), p. 487-504
- Full Text:
- Reviewed:
- Description: Background: Little is known about the health literacy of children living with long-term conditions. This study aimed to gain insight into the life of children with a long-term condition in the context of health literacy, specifically their understanding of their health and the barriers and facilitators to sharing information about their condition with others. Design: Child-centred qualitative arts-based approach with children aged 6–12 years. Setting: Children participating in the study came from three countries – the UK, Australia and New Zealand. Method: A participatory arts-based qualitative child-centred approach prompted children to draw, label and use stickers, body-outlines and collage to describe elements central to health literacy. This encompassed their long-term condition, their understanding of their condition, its management and decision-making associated with sharing information about their condition with others. The sessions were audio-recorded, and reflexive thematic analysis was undertaken. Results: Four central themes related to key elements of child health literacy: (1) pragmatic understanding – what it feels like and what happens in my body; (2) management regime – what do I have to do to keep on going; (3) information sharing – I don’t tell random people; and (4) benefits of sharing – they’ve got my back. Conclusion: Children indicated a pragmatic or process type understanding of their condition and its management. Children were discerning about who they shared information about their condition with, but tended to establish a network of well-informed peers capable of providing support if needed. Despite gaps in children’s health literacy, parents and families have an important role to play in checking children’s understandings and developing critical health literacy. © The Author(s) 2023.
- Authors: Peck, Blake , Bray, Lucy , Dickinson, Annette , Blamires, Julie , Terry, Daniel , Carter, Bernie
- Date: 2023
- Type: Text , Journal article
- Relation: Health Education Journal Vol. 82, no. 5 (2023), p. 487-504
- Full Text:
- Reviewed:
- Description: Background: Little is known about the health literacy of children living with long-term conditions. This study aimed to gain insight into the life of children with a long-term condition in the context of health literacy, specifically their understanding of their health and the barriers and facilitators to sharing information about their condition with others. Design: Child-centred qualitative arts-based approach with children aged 6–12 years. Setting: Children participating in the study came from three countries – the UK, Australia and New Zealand. Method: A participatory arts-based qualitative child-centred approach prompted children to draw, label and use stickers, body-outlines and collage to describe elements central to health literacy. This encompassed their long-term condition, their understanding of their condition, its management and decision-making associated with sharing information about their condition with others. The sessions were audio-recorded, and reflexive thematic analysis was undertaken. Results: Four central themes related to key elements of child health literacy: (1) pragmatic understanding – what it feels like and what happens in my body; (2) management regime – what do I have to do to keep on going; (3) information sharing – I don’t tell random people; and (4) benefits of sharing – they’ve got my back. Conclusion: Children indicated a pragmatic or process type understanding of their condition and its management. Children were discerning about who they shared information about their condition with, but tended to establish a network of well-informed peers capable of providing support if needed. Despite gaps in children’s health literacy, parents and families have an important role to play in checking children’s understandings and developing critical health literacy. © The Author(s) 2023.
Hermeneutic constructivism : one ontology for authentic understanding
- Authors: Peck, Blake , Mummery, Jane
- Date: 2023
- Type: Text , Journal article
- Relation: Nursing Inquiry Vol. 30, no. 2 (2023), p.
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- Description: Nursing and nurses rely upon qualitative research to understand the intricacies of the human condition. Acknowledging the subjective nature of reality and commonly founded in a constructivist epistemology, qualitative approaches offer opportunities for uncovering insights from the perspective of the individual participants, the insider's view, and the construction of representations that maintain an intimacy with the subject's realities. Debate continues, however, about what is needed for a qualitative construction to be considered an authentic understanding of a subject's realities. Authenticity in the context of qualitative research has been described as entailing consideration of a number of well‐trodden dimensions: fairness, ontological, educative, catalytic and tactical. Taking these dimensional requirements as key, this paper argues that authenticity may not always be as well‐developed through some of the standard practices in qualitative research as perhaps expected. In particular, qualitative understandings of authenticity stress that participants should not be merely reported on but instead should be dynamically involved in and changed by the constructions and interpretations of data developed throughout the research process. As this paper illustrates, such engagements appear problematic for qualitative research approaches that are beholden to designative commitments in the context of language and meaning‐making and which tend to prioritise commonality and generality at the expense of individual authenticity. An alternative qualitative approach, Hermeneutic Constructivism, is proposed as better able to achieve the requirements of the dimensions of authenticity. As outlined, this approach is well‐placed to present an understanding of human experience through a genuinely expressivist approach and transcends the stress upon the common or the general that can be pervasive and problematic.
- Authors: Peck, Blake , Mummery, Jane
- Date: 2023
- Type: Text , Journal article
- Relation: Nursing Inquiry Vol. 30, no. 2 (2023), p.
- Full Text:
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- Description: Nursing and nurses rely upon qualitative research to understand the intricacies of the human condition. Acknowledging the subjective nature of reality and commonly founded in a constructivist epistemology, qualitative approaches offer opportunities for uncovering insights from the perspective of the individual participants, the insider's view, and the construction of representations that maintain an intimacy with the subject's realities. Debate continues, however, about what is needed for a qualitative construction to be considered an authentic understanding of a subject's realities. Authenticity in the context of qualitative research has been described as entailing consideration of a number of well‐trodden dimensions: fairness, ontological, educative, catalytic and tactical. Taking these dimensional requirements as key, this paper argues that authenticity may not always be as well‐developed through some of the standard practices in qualitative research as perhaps expected. In particular, qualitative understandings of authenticity stress that participants should not be merely reported on but instead should be dynamically involved in and changed by the constructions and interpretations of data developed throughout the research process. As this paper illustrates, such engagements appear problematic for qualitative research approaches that are beholden to designative commitments in the context of language and meaning‐making and which tend to prioritise commonality and generality at the expense of individual authenticity. An alternative qualitative approach, Hermeneutic Constructivism, is proposed as better able to achieve the requirements of the dimensions of authenticity. As outlined, this approach is well‐placed to present an understanding of human experience through a genuinely expressivist approach and transcends the stress upon the common or the general that can be pervasive and problematic.
High-intensity interval training for the management of nonalcoholic steatohepatitis : participant experiences and perspectives
- Keating, Shelley, Croci, Ilaria, Wallen, Matthew, Cox, Emily, Coombes, Jeff, Burton, Nicola, Macdonald, Graeme, Hickman, Ingrid
- Authors: Keating, Shelley , Croci, Ilaria , Wallen, Matthew , Cox, Emily , Coombes, Jeff , Burton, Nicola , Macdonald, Graeme , Hickman, Ingrid
- Date: 2023
- Type: Text , Journal article
- Relation: Journal of Clinical and Translational Hepatology Vol. 11, no. 5 (2023), p. 1050-1060
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- Description: Background and Aims: High-intensity interval training (HIIT) is a therapeutic option for people with nonalcoholic steatohepatitis (NASH). However, the perspectives and experiences of HIIT for people with NASH are unknown, limiting translation of research. We explored the experiences and perspectives of both professionally supervised and self-directed HIIT in people with NASH and evaluated participant-reported knowledge, barriers, and enablers to commencing and sus-taining HIIT. Methods: Twelve participants with NASH un-derwent 12 weeks of supervised HIIT (3 days/week, 4×4 minutes at 85–95% maximal heart rate, interspersed with 3 minutes active recovery), followed by 12-weeks of self-directed (unsupervised) HIIT. One-on-one, semistructured participant interviews were conducted by exercise staff prior to HIIT and following both supervised and self-directed HIIT to explore prior knowledge, barriers, enablers, and outcomes at each stage. Interviews were audio-recorded, transcribed, coded, and thematically analyzed by two independent re-searchers. Results: Four dominant themes were identified: (1) no awareness of/experience with HIIT and ambivalence about exercise capabilities; (2) multiple medical and social barriers to commencing and continuing HIIT; (3) exercise specialist support was a highly valued enabler, and (4) HIIT was enjoyed and provided holistic benefits. Conclusions: People with NASH may lack knowledge of and confidence for HIIT, and experience multiple complex barriers to commencing and continuing HIIT. Exercise specialist support is a key enabler to sustained engagement. These factors need to be addressed in future clinical programs to augment the uptake and long-term sustainability of HIIT by people with NASH so they can experience the range of related benefits. © 2023 The Author(s).
- Authors: Keating, Shelley , Croci, Ilaria , Wallen, Matthew , Cox, Emily , Coombes, Jeff , Burton, Nicola , Macdonald, Graeme , Hickman, Ingrid
- Date: 2023
- Type: Text , Journal article
- Relation: Journal of Clinical and Translational Hepatology Vol. 11, no. 5 (2023), p. 1050-1060
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- Description: Background and Aims: High-intensity interval training (HIIT) is a therapeutic option for people with nonalcoholic steatohepatitis (NASH). However, the perspectives and experiences of HIIT for people with NASH are unknown, limiting translation of research. We explored the experiences and perspectives of both professionally supervised and self-directed HIIT in people with NASH and evaluated participant-reported knowledge, barriers, and enablers to commencing and sus-taining HIIT. Methods: Twelve participants with NASH un-derwent 12 weeks of supervised HIIT (3 days/week, 4×4 minutes at 85–95% maximal heart rate, interspersed with 3 minutes active recovery), followed by 12-weeks of self-directed (unsupervised) HIIT. One-on-one, semistructured participant interviews were conducted by exercise staff prior to HIIT and following both supervised and self-directed HIIT to explore prior knowledge, barriers, enablers, and outcomes at each stage. Interviews were audio-recorded, transcribed, coded, and thematically analyzed by two independent re-searchers. Results: Four dominant themes were identified: (1) no awareness of/experience with HIIT and ambivalence about exercise capabilities; (2) multiple medical and social barriers to commencing and continuing HIIT; (3) exercise specialist support was a highly valued enabler, and (4) HIIT was enjoyed and provided holistic benefits. Conclusions: People with NASH may lack knowledge of and confidence for HIIT, and experience multiple complex barriers to commencing and continuing HIIT. Exercise specialist support is a key enabler to sustained engagement. These factors need to be addressed in future clinical programs to augment the uptake and long-term sustainability of HIIT by people with NASH so they can experience the range of related benefits. © 2023 The Author(s).
High-intensity interval training is safe, feasible and efficacious in nonalcoholic steatohepatitis : a randomized controlled trial
- Keating, Shelley, Croci, Ilaria, Wallen, Matthew, Cox, Emily, Thuzar, Moe, Pham, Uyen, Mielke, Gregore, Coombes, Jeff, Macdonald, Graeme, Hickman, Ingrid
- Authors: Keating, Shelley , Croci, Ilaria , Wallen, Matthew , Cox, Emily , Thuzar, Moe , Pham, Uyen , Mielke, Gregore , Coombes, Jeff , Macdonald, Graeme , Hickman, Ingrid
- Date: 2023
- Type: Text , Journal article
- Relation: Digestive Diseases and Sciences Vol. 68, no. 5 (2023), p. 2123-2139
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- Description: Background: High-Intensity Interval Training (HIIT) involves bursts of high-intensity exercise interspersed with lower-intensity exercise recovery. HIIT may benefit cardiometabolic health in people with nonalcoholic steatohepatitis (NASH). Aims: We aimed to examine the safety, feasibility, and efficacy of 12-weeks of supervised HIIT compared with a sham-exercise control (CON) for improving aerobic fitness and peripheral insulin sensitivity in biopsy-proven NASH. Methods: Participants based in the community [(n = 14, 56 ± 10 years, BMI 39.2 ± 6.7 kg/m2, 64% male), NAFLD Activity Score 5 (range 3–7)] were randomized to 12-weeks of supervised HIIT (n = 8, 4 × 4 min at 85–95% maximal heart rate, interspersed with 3 min active recovery; 3 days/week) or CON (n = 6, stretching; 3 days/week). Safety (adverse events) and feasibility determined as
- Authors: Keating, Shelley , Croci, Ilaria , Wallen, Matthew , Cox, Emily , Thuzar, Moe , Pham, Uyen , Mielke, Gregore , Coombes, Jeff , Macdonald, Graeme , Hickman, Ingrid
- Date: 2023
- Type: Text , Journal article
- Relation: Digestive Diseases and Sciences Vol. 68, no. 5 (2023), p. 2123-2139
- Full Text:
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- Description: Background: High-Intensity Interval Training (HIIT) involves bursts of high-intensity exercise interspersed with lower-intensity exercise recovery. HIIT may benefit cardiometabolic health in people with nonalcoholic steatohepatitis (NASH). Aims: We aimed to examine the safety, feasibility, and efficacy of 12-weeks of supervised HIIT compared with a sham-exercise control (CON) for improving aerobic fitness and peripheral insulin sensitivity in biopsy-proven NASH. Methods: Participants based in the community [(n = 14, 56 ± 10 years, BMI 39.2 ± 6.7 kg/m2, 64% male), NAFLD Activity Score 5 (range 3–7)] were randomized to 12-weeks of supervised HIIT (n = 8, 4 × 4 min at 85–95% maximal heart rate, interspersed with 3 min active recovery; 3 days/week) or CON (n = 6, stretching; 3 days/week). Safety (adverse events) and feasibility determined as
Human engagement providing evaluative and informative advice for interactive reinforcement learning
- Bignold, Adam, Cruz, Francisco, Dazeley, Richard, Vamplew, Peter, Foale, Cameron
- Authors: Bignold, Adam , Cruz, Francisco , Dazeley, Richard , Vamplew, Peter , Foale, Cameron
- Date: 2023
- Type: Text , Journal article
- Relation: Neural Computing and Applications Vol. 35, no. 25 (2023), p. 18215-18230
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- Description: Interactive reinforcement learning proposes the use of externally sourced information in order to speed up the learning process. When interacting with a learner agent, humans may provide either evaluative or informative advice. Prior research has focused on the effect of human-sourced advice by including real-time feedback on the interactive reinforcement learning process, specifically aiming to improve the learning speed of the agent, while minimising the time demands on the human. This work focuses on answering which of two approaches, evaluative or informative, is the preferred instructional approach for humans. Moreover, this work presents an experimental setup for a human trial designed to compare the methods people use to deliver advice in terms of human engagement. The results obtained show that users giving informative advice to the learner agents provide more accurate advice, are willing to assist the learner agent for a longer time, and provide more advice per episode. Additionally, self-evaluation from participants using the informative approach has indicated that the agent’s ability to follow the advice is higher, and therefore, they feel their own advice to be of higher accuracy when compared to people providing evaluative advice. © 2022, The Author(s).
- Authors: Bignold, Adam , Cruz, Francisco , Dazeley, Richard , Vamplew, Peter , Foale, Cameron
- Date: 2023
- Type: Text , Journal article
- Relation: Neural Computing and Applications Vol. 35, no. 25 (2023), p. 18215-18230
- Full Text:
- Reviewed:
- Description: Interactive reinforcement learning proposes the use of externally sourced information in order to speed up the learning process. When interacting with a learner agent, humans may provide either evaluative or informative advice. Prior research has focused on the effect of human-sourced advice by including real-time feedback on the interactive reinforcement learning process, specifically aiming to improve the learning speed of the agent, while minimising the time demands on the human. This work focuses on answering which of two approaches, evaluative or informative, is the preferred instructional approach for humans. Moreover, this work presents an experimental setup for a human trial designed to compare the methods people use to deliver advice in terms of human engagement. The results obtained show that users giving informative advice to the learner agents provide more accurate advice, are willing to assist the learner agent for a longer time, and provide more advice per episode. Additionally, self-evaluation from participants using the informative approach has indicated that the agent’s ability to follow the advice is higher, and therefore, they feel their own advice to be of higher accuracy when compared to people providing evaluative advice. © 2022, The Author(s).
Human strongyloidiasis : complexities and pathways forward
- Buonfrate, Dora, Bradbury, Richard, Watts, Matthew, Bisoffi, Zeno
- Authors: Buonfrate, Dora , Bradbury, Richard , Watts, Matthew , Bisoffi, Zeno
- Date: 2023
- Type: Text , Journal article , Review
- Relation: Clinical Microbiology Reviews Vol. 36, no. 4 (2023), p.
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- Description: Strongyloidiasis is a World Health Organization neglected tropical disease usually caused by Strongyloides stercoralis, a parasitic worm with a complex life cycle. Globally, 300-600 million people are infected through contact with fecally contaminated soil. An autoinfective component of the life cycle can lead to chronic infection that may be asymptomatic or cause long-term symptoms, including malnourishment in children. Low larval output can limit the sensitivity of detection in stool, with serology being effectivebut less sensitive in immunocompromise. Host immunosuppression can trigger catastrophic, fatal hyperinfection/dissemination, where large numbers of larvae pierce the bowel wall and disseminate throughout the organs. Stable disease is effectivelytreated by single-dose ivermectin, with disease in immunocompromised patients treated with multiple doses. Strategies for management include raising awareness, clarifying zoonotic potential, the development and use of effectivediagnostic tests for epidemiological studies and individual diagnosis, and the implementation of treatment programs with research into therapeutic alternatives and medication safety. © 2023 American Society for Microbiology. All rights reserved.
- Authors: Buonfrate, Dora , Bradbury, Richard , Watts, Matthew , Bisoffi, Zeno
- Date: 2023
- Type: Text , Journal article , Review
- Relation: Clinical Microbiology Reviews Vol. 36, no. 4 (2023), p.
- Full Text:
- Reviewed:
- Description: Strongyloidiasis is a World Health Organization neglected tropical disease usually caused by Strongyloides stercoralis, a parasitic worm with a complex life cycle. Globally, 300-600 million people are infected through contact with fecally contaminated soil. An autoinfective component of the life cycle can lead to chronic infection that may be asymptomatic or cause long-term symptoms, including malnourishment in children. Low larval output can limit the sensitivity of detection in stool, with serology being effectivebut less sensitive in immunocompromise. Host immunosuppression can trigger catastrophic, fatal hyperinfection/dissemination, where large numbers of larvae pierce the bowel wall and disseminate throughout the organs. Stable disease is effectivelytreated by single-dose ivermectin, with disease in immunocompromised patients treated with multiple doses. Strategies for management include raising awareness, clarifying zoonotic potential, the development and use of effectivediagnostic tests for epidemiological studies and individual diagnosis, and the implementation of treatment programs with research into therapeutic alternatives and medication safety. © 2023 American Society for Microbiology. All rights reserved.
Hybridisation rates, population structure, and dispersal of sambar deer (Cervus unicolor) and rusa deer (Cervus timorensis) in south-eastern Australia
- Hill, Erin, Murphy, Nicholas, Li-Williams, Scarlett, Davies, Christopher, Forsyth, David, Comte, Sebastien, Rollins, Lee, Hogan, Fiona, Wedrowicz, Faye, Crittle, Troy, Thomas, Elaine, Woodford, Luke, Pacioni, Carlo
- Authors: Hill, Erin , Murphy, Nicholas , Li-Williams, Scarlett , Davies, Christopher , Forsyth, David , Comte, Sebastien , Rollins, Lee , Hogan, Fiona , Wedrowicz, Faye , Crittle, Troy , Thomas, Elaine , Woodford, Luke , Pacioni, Carlo
- Date: 2023
- Type: Text , Journal article
- Relation: Wildlife Research Vol. 50, no. 9 (2023), p. 669-687
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- Description: Context. Introduced populations of sambar deer (Cervus unicolor) and rusa deer (Cervus timorensis) are present across south-eastern Australia and are subject to local population control to alleviate their negative impacts. For management to be effective, identification of dispersal capability and management units is necessary. These species also readily hybridise, so additional investigation of hybridisation rates across their distributions is necessary to understand the interactions between the two species. Aims. Measure the hybridisation rate of sambar and rusa deer, assess broad-scale population structure present within both species and identify distinct management units for future population control, and measure the likely dispersal capability of both species. Methods. In total, 198 sambar deer, 189 rusa deer, and three suspected hybrid samples were collected across Victoria and New South Wales (NSW). After sequencing and filtering, 14 099 polymorphic single-nucleotide polymorphism (SNP) markers were retained for analysis. Hybridisation rates were assessed before the data were split by species to identify population structure, diversity indices, and dispersal distances. Key results. Across the entire dataset, 17 hybrids were detected. Broad-scale population structure was evident in sambar deer, but not among the sites where rusa deer were sampled. Analysis of dispersal ability showed that a majority of deer movement occurred within 20 km in both species, suggesting limited dispersal. Conclusions. Distinct management units of sambar deer can be identified from the dataset, allowing independent population control. Although broad-scale population structure was not evident in the rusa deer populations, dispersal limits identified suggest that rusa deer sites sampled in this study could be managed separately. Sambar × rusa deer hybrids are present in both Victoria and NSW and can be difficult to detect on the basis of morphology alone. Implications. Genetic analysis can identify broad-scale management units necessary for population control, and estimates of dispersal capability can assist in delineating management units where broad-scale population structure may not be apparent. The negative impacts associated with hybridisation require further investigation to determine whether removal of hybrids should be considered a priority management aim. © 2023 The Author(s) (or their employer(s)). Published by CSIRO Publishing.
- Authors: Hill, Erin , Murphy, Nicholas , Li-Williams, Scarlett , Davies, Christopher , Forsyth, David , Comte, Sebastien , Rollins, Lee , Hogan, Fiona , Wedrowicz, Faye , Crittle, Troy , Thomas, Elaine , Woodford, Luke , Pacioni, Carlo
- Date: 2023
- Type: Text , Journal article
- Relation: Wildlife Research Vol. 50, no. 9 (2023), p. 669-687
- Full Text:
- Reviewed:
- Description: Context. Introduced populations of sambar deer (Cervus unicolor) and rusa deer (Cervus timorensis) are present across south-eastern Australia and are subject to local population control to alleviate their negative impacts. For management to be effective, identification of dispersal capability and management units is necessary. These species also readily hybridise, so additional investigation of hybridisation rates across their distributions is necessary to understand the interactions between the two species. Aims. Measure the hybridisation rate of sambar and rusa deer, assess broad-scale population structure present within both species and identify distinct management units for future population control, and measure the likely dispersal capability of both species. Methods. In total, 198 sambar deer, 189 rusa deer, and three suspected hybrid samples were collected across Victoria and New South Wales (NSW). After sequencing and filtering, 14 099 polymorphic single-nucleotide polymorphism (SNP) markers were retained for analysis. Hybridisation rates were assessed before the data were split by species to identify population structure, diversity indices, and dispersal distances. Key results. Across the entire dataset, 17 hybrids were detected. Broad-scale population structure was evident in sambar deer, but not among the sites where rusa deer were sampled. Analysis of dispersal ability showed that a majority of deer movement occurred within 20 km in both species, suggesting limited dispersal. Conclusions. Distinct management units of sambar deer can be identified from the dataset, allowing independent population control. Although broad-scale population structure was not evident in the rusa deer populations, dispersal limits identified suggest that rusa deer sites sampled in this study could be managed separately. Sambar × rusa deer hybrids are present in both Victoria and NSW and can be difficult to detect on the basis of morphology alone. Implications. Genetic analysis can identify broad-scale management units necessary for population control, and estimates of dispersal capability can assist in delineating management units where broad-scale population structure may not be apparent. The negative impacts associated with hybridisation require further investigation to determine whether removal of hybrids should be considered a priority management aim. © 2023 The Author(s) (or their employer(s)). Published by CSIRO Publishing.
Hybridizing five neural-metaheuristic paradigms to predict the pillar stress in bord and pillar method
- Zhou, Jian, Chen, Yuxin, Chen, Hui, Khandelwal, Manoj, Monjezi, Masoud, Peng, Kang
- Authors: Zhou, Jian , Chen, Yuxin , Chen, Hui , Khandelwal, Manoj , Monjezi, Masoud , Peng, Kang
- Date: 2023
- Type: Text , Journal article
- Relation: Frontiers in Public Health Vol. 11, no. (2023), p.
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- Description: Pillar stability is an important condition for safe work in room-and-pillar mines. The instability of pillars will lead to large-scale collapse hazards, and the accurate estimation of induced stresses at different positions in the pillar is helpful for pillar design and guaranteeing pillar stability. There are many modeling methods to design pillars and evaluate their stability, including empirical and numerical method. However, empirical methods are difficult to be applied to places other than the original environmental characteristics, and numerical methods often simplify the boundary conditions and material properties, which cannot guarantee the stability of the design. Currently, machine learning (ML) algorithms have been successfully applied to pillar stability assessment with higher accuracy. Thus, the study adopted a back-propagation neural network (BPNN) and five elements including the sparrow search algorithm (SSA), gray wolf optimizer (GWO), butterfly optimization algorithm (BOA), tunicate swarm algorithm (TSA), and multi-verse optimizer (MVO). Combining metaheuristic algorithms, five hybrid models were developed to predict the induced stress within the pillar. The weight and threshold of the BPNN model are optimized by metaheuristic algorithms, in which the mean absolute error (MAE) is utilized as the fitness function. A database containing 149 data samples was established, where the input variables were the angle of goafline (A), depth of the working coal seam (H), specific gravity (G), distance of the point from the center of the pillar (C), and distance of the point from goafline (D), and the output variable was the induced stress. Furthermore, the predictive performance of the proposed model is evaluated by five metrics, namely coefficient of determination (R2), root mean squared error (RMSE), variance accounted for (VAF), mean absolute error (MAE), and mean absolute percentage error (MAPE). The results showed that the five hybrid models developed have good prediction performance, especially the GWO-BPNN model performed the best (Training set: R2 = 0.9991, RMSE = 0.1535, VAF = 99.91, MAE = 0.0884, MAPE = 0.6107; Test set: R2 = 0.9983, RMSE = 0.1783, VAF = 99.83, MAE = 0.1230, MAPE = 0.9253). Copyright © 2023 Zhou, Chen, Chen, Khandelwal, Monjezi and Peng.
- Authors: Zhou, Jian , Chen, Yuxin , Chen, Hui , Khandelwal, Manoj , Monjezi, Masoud , Peng, Kang
- Date: 2023
- Type: Text , Journal article
- Relation: Frontiers in Public Health Vol. 11, no. (2023), p.
- Full Text:
- Reviewed:
- Description: Pillar stability is an important condition for safe work in room-and-pillar mines. The instability of pillars will lead to large-scale collapse hazards, and the accurate estimation of induced stresses at different positions in the pillar is helpful for pillar design and guaranteeing pillar stability. There are many modeling methods to design pillars and evaluate their stability, including empirical and numerical method. However, empirical methods are difficult to be applied to places other than the original environmental characteristics, and numerical methods often simplify the boundary conditions and material properties, which cannot guarantee the stability of the design. Currently, machine learning (ML) algorithms have been successfully applied to pillar stability assessment with higher accuracy. Thus, the study adopted a back-propagation neural network (BPNN) and five elements including the sparrow search algorithm (SSA), gray wolf optimizer (GWO), butterfly optimization algorithm (BOA), tunicate swarm algorithm (TSA), and multi-verse optimizer (MVO). Combining metaheuristic algorithms, five hybrid models were developed to predict the induced stress within the pillar. The weight and threshold of the BPNN model are optimized by metaheuristic algorithms, in which the mean absolute error (MAE) is utilized as the fitness function. A database containing 149 data samples was established, where the input variables were the angle of goafline (A), depth of the working coal seam (H), specific gravity (G), distance of the point from the center of the pillar (C), and distance of the point from goafline (D), and the output variable was the induced stress. Furthermore, the predictive performance of the proposed model is evaluated by five metrics, namely coefficient of determination (R2), root mean squared error (RMSE), variance accounted for (VAF), mean absolute error (MAE), and mean absolute percentage error (MAPE). The results showed that the five hybrid models developed have good prediction performance, especially the GWO-BPNN model performed the best (Training set: R2 = 0.9991, RMSE = 0.1535, VAF = 99.91, MAE = 0.0884, MAPE = 0.6107; Test set: R2 = 0.9983, RMSE = 0.1783, VAF = 99.83, MAE = 0.1230, MAPE = 0.9253). Copyright © 2023 Zhou, Chen, Chen, Khandelwal, Monjezi and Peng.
Identifying complementary and alternative medicine recommendations for anxiety treatment and care : a systematic review and critical assessment of comprehensive clinical practice guidelines
- Zhao, Fei-Yi, Kennedy, Gerard, Xu, Peijie, Conduit, Russell, Wang, Yan-Mei, Zhang, Wen-Jing, Wang, Hui-Ru, Yue, Li-Ping, Huang, Yu-Ling, Wang, Yin, Xu, Yan, Fu, Qiang-Qiang, Zheng, Zhen
- Authors: Zhao, Fei-Yi , Kennedy, Gerard , Xu, Peijie , Conduit, Russell , Wang, Yan-Mei , Zhang, Wen-Jing , Wang, Hui-Ru , Yue, Li-Ping , Huang, Yu-Ling , Wang, Yin , Xu, Yan , Fu, Qiang-Qiang , Zheng, Zhen
- Date: 2023
- Type: Text , Journal article , Review
- Relation: Frontiers in Psychiatry Vol. 14, no. (2023), p.
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- Description: Background: Clinical practice guidelines (CPGs) are used to guide decision-making, especially regarding complementary and alternative medicine (CAM) therapies that are unfamiliar to orthodox healthcare providers. This systematic review aimed to critically review and summarise CAM recommendations associated with anxiety management included in the existing CPGs. Methods: Seven databases, websites of six international guidelines developing institutions, and the National Centre for Complementary and Integrative Health website were systematically searched. Their reporting and methodological quality were evaluated using the Reporting Items for practice Guidelines in Healthcare checklist and the Appraisal of Guidelines for Research and Evaluation (2nd version) instrument, respectively. Results: Ten CPGs were included, with reporting rates between 51.4 and 88.6%. Seven of these were of moderate to high methodological quality. Seventeen CAM modalities were implicated, involving phytotherapeutics, mind–body practice, art therapy, and homeopathy. Applied relaxation was included in 70% CPGs, which varied in degree of support for its use in the treatment of generalised anxiety disorder. There were few recommendations for other therapies/products. Light therapy was not recommended for use in generalised anxiety disorder, and St John’s wort and mindfulness were not recommended for use in social anxiety disorder in individual guidelines. Recommendations for the applicability of other therapies/products for treating a specific anxiety disorder were commonly graded as “unclear, unambiguous, or uncertain”. No CAM recommendations were provided for separation anxiety disorder, specific phobia or selective mutism. Conclusion: Available guidelines are limited in providing logically explained graded CAM recommendations for anxiety treatment and care. A lack of high-quality evidence and multidisciplinary consultation during the guideline development are two major reasons. High quality and reliable clinical evidence and the engagement of a range of interdisciplinary stakeholders are needed for future CPG development and updating. Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022373694, identifier CRD42022373694. Copyright © 2023 Zhao, Kennedy, Xu, Conduit, Wang, Zhang, Wang, Yue, Huang, Wang, Xu, Fu and Zheng.
- Authors: Zhao, Fei-Yi , Kennedy, Gerard , Xu, Peijie , Conduit, Russell , Wang, Yan-Mei , Zhang, Wen-Jing , Wang, Hui-Ru , Yue, Li-Ping , Huang, Yu-Ling , Wang, Yin , Xu, Yan , Fu, Qiang-Qiang , Zheng, Zhen
- Date: 2023
- Type: Text , Journal article , Review
- Relation: Frontiers in Psychiatry Vol. 14, no. (2023), p.
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- Description: Background: Clinical practice guidelines (CPGs) are used to guide decision-making, especially regarding complementary and alternative medicine (CAM) therapies that are unfamiliar to orthodox healthcare providers. This systematic review aimed to critically review and summarise CAM recommendations associated with anxiety management included in the existing CPGs. Methods: Seven databases, websites of six international guidelines developing institutions, and the National Centre for Complementary and Integrative Health website were systematically searched. Their reporting and methodological quality were evaluated using the Reporting Items for practice Guidelines in Healthcare checklist and the Appraisal of Guidelines for Research and Evaluation (2nd version) instrument, respectively. Results: Ten CPGs were included, with reporting rates between 51.4 and 88.6%. Seven of these were of moderate to high methodological quality. Seventeen CAM modalities were implicated, involving phytotherapeutics, mind–body practice, art therapy, and homeopathy. Applied relaxation was included in 70% CPGs, which varied in degree of support for its use in the treatment of generalised anxiety disorder. There were few recommendations for other therapies/products. Light therapy was not recommended for use in generalised anxiety disorder, and St John’s wort and mindfulness were not recommended for use in social anxiety disorder in individual guidelines. Recommendations for the applicability of other therapies/products for treating a specific anxiety disorder were commonly graded as “unclear, unambiguous, or uncertain”. No CAM recommendations were provided for separation anxiety disorder, specific phobia or selective mutism. Conclusion: Available guidelines are limited in providing logically explained graded CAM recommendations for anxiety treatment and care. A lack of high-quality evidence and multidisciplinary consultation during the guideline development are two major reasons. High quality and reliable clinical evidence and the engagement of a range of interdisciplinary stakeholders are needed for future CPG development and updating. Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022373694, identifier CRD42022373694. Copyright © 2023 Zhao, Kennedy, Xu, Conduit, Wang, Zhang, Wang, Yue, Huang, Wang, Xu, Fu and Zheng.
Identifying complementary and alternative medicine recommendations for insomnia treatment and care : a systematic review and critical assessment of comprehensive clinical practice guidelines
- Zhao, Fei-Yi. Y., Xu, Peijie, Kennedy, Gerard, Conduit, Russell, Zhang, Wen-Jing, Wang, Yan-Mei, Fu, Qiang-Qiang, Zheng, Zhen
- Authors: Zhao, Fei-Yi. Y. , Xu, Peijie , Kennedy, Gerard , Conduit, Russell , Zhang, Wen-Jing , Wang, Yan-Mei , Fu, Qiang-Qiang , Zheng, Zhen
- Date: 2023
- Type: Text , Journal article , Review
- Relation: Frontiers in Public Health Vol. 11, no. (2023), p.
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- Description: Background: There is a need for evidence-informed guidance on the use of complementary and alternative medicine (CAM) for insomnia because of its widespread utilization and a lack of guidance on the balance of benefits and harms. This systematic review aimed to identify and summarize the CAM recommendations associated with insomnia treatment and care from existing comprehensive clinical practice guidelines (CPGs). The quality of the eligible guidelines was appraised to assess the credibility of these recommendations. Methods: Formally published CPGs incorporating CAM recommendations for insomnia management were searched for in seven databases from their inception to January 2023. The NCCIH website and six websites of international guideline developing institutions were also retrieved. The methodological and reporting quality of each included guideline was appraised using the AGREE II instrument and RIGHT statement, respectively. Results: Seventeen eligible GCPs were included, and 14 were judged to be of moderate to high methodological and reporting quality. The reporting rate of eligible CPGs ranged from 42.9 to 97.1%. Twenty-two CAM modalities were implicated, involving nutritional or natural products, physical CAM, psychological CAM, homeopathy, aromatherapy, and mindful movements. Recommendations for these modalities were mostly unclear, unambiguous, uncertain, or conflicting. Logically explained graded recommendations supporting the CAM use in the treatment and/or care of insomnia were scarce, with bibliotherapy, Tai Chi, Yoga, and auriculotherapy positively recommended based on little and weak evidence. The only consensus was that four phytotherapeutics including valerian, chamomile, kava, and aromatherapy were not recommended for insomnia management because of risk profile and/or limited benefits. Conclusions: Existing guidelines are generally limited in providing clear, evidence-informed recommendations for the use of CAM therapies for insomnia management due to a lack of high-quality evidence and multidisciplinary consultation in CPG development. More well-designed studies to provide reliable clinical evidence are therefore urgently needed. Allowing the engagement of a range of interdisciplinary stakeholders in future updates of CPGs is also warranted. Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=369155, identifier: CRD42022369155. Copyright © 2023 Zhao, Xu, Kennedy, Conduit, Zhang, Wang, Fu and Zheng.
- Authors: Zhao, Fei-Yi. Y. , Xu, Peijie , Kennedy, Gerard , Conduit, Russell , Zhang, Wen-Jing , Wang, Yan-Mei , Fu, Qiang-Qiang , Zheng, Zhen
- Date: 2023
- Type: Text , Journal article , Review
- Relation: Frontiers in Public Health Vol. 11, no. (2023), p.
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- Description: Background: There is a need for evidence-informed guidance on the use of complementary and alternative medicine (CAM) for insomnia because of its widespread utilization and a lack of guidance on the balance of benefits and harms. This systematic review aimed to identify and summarize the CAM recommendations associated with insomnia treatment and care from existing comprehensive clinical practice guidelines (CPGs). The quality of the eligible guidelines was appraised to assess the credibility of these recommendations. Methods: Formally published CPGs incorporating CAM recommendations for insomnia management were searched for in seven databases from their inception to January 2023. The NCCIH website and six websites of international guideline developing institutions were also retrieved. The methodological and reporting quality of each included guideline was appraised using the AGREE II instrument and RIGHT statement, respectively. Results: Seventeen eligible GCPs were included, and 14 were judged to be of moderate to high methodological and reporting quality. The reporting rate of eligible CPGs ranged from 42.9 to 97.1%. Twenty-two CAM modalities were implicated, involving nutritional or natural products, physical CAM, psychological CAM, homeopathy, aromatherapy, and mindful movements. Recommendations for these modalities were mostly unclear, unambiguous, uncertain, or conflicting. Logically explained graded recommendations supporting the CAM use in the treatment and/or care of insomnia were scarce, with bibliotherapy, Tai Chi, Yoga, and auriculotherapy positively recommended based on little and weak evidence. The only consensus was that four phytotherapeutics including valerian, chamomile, kava, and aromatherapy were not recommended for insomnia management because of risk profile and/or limited benefits. Conclusions: Existing guidelines are generally limited in providing clear, evidence-informed recommendations for the use of CAM therapies for insomnia management due to a lack of high-quality evidence and multidisciplinary consultation in CPG development. More well-designed studies to provide reliable clinical evidence are therefore urgently needed. Allowing the engagement of a range of interdisciplinary stakeholders in future updates of CPGs is also warranted. Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=369155, identifier: CRD42022369155. Copyright © 2023 Zhao, Xu, Kennedy, Conduit, Zhang, Wang, Fu and Zheng.
Identifying factors affecting work-integrated learning opportunities in exercise science and exercise physiology
- Buchan, Jena, Pitcher, Christian, Pascoe, Deborah, McGowan, Courtney, Clanchy, Kelly, Sealey, Rebecca
- Authors: Buchan, Jena , Pitcher, Christian , Pascoe, Deborah , McGowan, Courtney , Clanchy, Kelly , Sealey, Rebecca
- Date: 2023
- Type: Text , Journal article
- Relation: International Journal of Work-Integrated Learning Vol. 24, no. 2 (2023), p. 241-259
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- Description: Support from industry professionals is essential to meet the increasing demand for high-quality work-integrated learning (WIL) that forms a core component of university curriculum in various health professions. This qualitative study used an online survey to investigate the current landscape of exercise science and physiology WIL opportunities in Australia, building from a previous 2013 study. Factors were identified from 76 practicum supervisors that restrict and promote willingness to provide WIL opportunities, with recommendations made on how to better support and engage current and future supervisors. Fifteen factors were identified that influenced supervisor WIL engagement, with four factors reported as 'promote', six factors reported as 'restrict' and five factors identified as promoting and restricting. Using these findings, recommendations were made around five key issues related to supporting sustainable, engaging future WIL opportunities. An update was also provided on status of recommendations resulting from the 2013 research and remaining areas for action. © 2023 International Journal of Work-Integrated Learning. All rights reserved.
- Authors: Buchan, Jena , Pitcher, Christian , Pascoe, Deborah , McGowan, Courtney , Clanchy, Kelly , Sealey, Rebecca
- Date: 2023
- Type: Text , Journal article
- Relation: International Journal of Work-Integrated Learning Vol. 24, no. 2 (2023), p. 241-259
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- Description: Support from industry professionals is essential to meet the increasing demand for high-quality work-integrated learning (WIL) that forms a core component of university curriculum in various health professions. This qualitative study used an online survey to investigate the current landscape of exercise science and physiology WIL opportunities in Australia, building from a previous 2013 study. Factors were identified from 76 practicum supervisors that restrict and promote willingness to provide WIL opportunities, with recommendations made on how to better support and engage current and future supervisors. Fifteen factors were identified that influenced supervisor WIL engagement, with four factors reported as 'promote', six factors reported as 'restrict' and five factors identified as promoting and restricting. Using these findings, recommendations were made around five key issues related to supporting sustainable, engaging future WIL opportunities. An update was also provided on status of recommendations resulting from the 2013 research and remaining areas for action. © 2023 International Journal of Work-Integrated Learning. All rights reserved.
Identifying public healthcare priorities in virtual care for older adults : a participatory research study
- Pu, Dai, Palmer, Victoria, Greenstock, Louise, Pigott, Cathie, Peeters, Anna, Sanci, Lena, Callisaya, Michele, Browning, Colette, Chapman, Wendy, Haines, Terry
- Authors: Pu, Dai , Palmer, Victoria , Greenstock, Louise , Pigott, Cathie , Peeters, Anna , Sanci, Lena , Callisaya, Michele , Browning, Colette , Chapman, Wendy , Haines, Terry
- Date: 2023
- Type: Text , Journal article
- Relation: International Journal of Environmental Research and Public Health Vol. 20, no. 5 (2023), p.
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- Description: There has been increasing adoption and implementation of virtual healthcare in recent years, especially with COVID-19 impacting the world. As a result, virtual care initiatives may not undergo stringent quality control processes to ensure that they are appropriate to their context and meet sector needs. The two objectives of this study were to identify virtual care initiatives for older adults currently in use in Victoria and virtual care challenges that could be prioritised for further investigation and scale-up and to understand why certain virtual care initiatives and challenges are prioritised over others for investigation and scale-up. Methods: This project used an Emerging Design approach. A survey of public health services in the state of Victoria in Australia was first carried out, followed by the co-production of research and healthcare priorities with key stakeholders in the areas of primary care, hospital care, consumer representation, research, and government. The survey was used to gather existing virtual care initiatives for older adults and any associated challenges. Co-production processes consisted of individual ratings of initiatives and group-based discussions to identify priority virtual care initiatives and challenges to be addressed for future scale-up. Stakeholders nominated their top three virtual initiatives following discussions. Results: Telehealth was nominated as the highest priority initiative type for scaling up, with virtual emergency department models of care nominated as the highest priority within this category. Remote monitoring was voted as a top priority for further investigations. The top virtual care challenge was data sharing across services and settings, and the user-friendliness of virtual care platforms was nominated as the top priority for further investigation. Conclusions: Stakeholders prioritised public health virtual care initiatives that are easy to adopt and address needs that are perceived to be more immediate (acute more so than chronic care). Virtual care initiatives that incorporate more technology and integrated elements are valued, but more information is needed to inform their potential scale-up. © 2023 by the authors.
- Authors: Pu, Dai , Palmer, Victoria , Greenstock, Louise , Pigott, Cathie , Peeters, Anna , Sanci, Lena , Callisaya, Michele , Browning, Colette , Chapman, Wendy , Haines, Terry
- Date: 2023
- Type: Text , Journal article
- Relation: International Journal of Environmental Research and Public Health Vol. 20, no. 5 (2023), p.
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- Description: There has been increasing adoption and implementation of virtual healthcare in recent years, especially with COVID-19 impacting the world. As a result, virtual care initiatives may not undergo stringent quality control processes to ensure that they are appropriate to their context and meet sector needs. The two objectives of this study were to identify virtual care initiatives for older adults currently in use in Victoria and virtual care challenges that could be prioritised for further investigation and scale-up and to understand why certain virtual care initiatives and challenges are prioritised over others for investigation and scale-up. Methods: This project used an Emerging Design approach. A survey of public health services in the state of Victoria in Australia was first carried out, followed by the co-production of research and healthcare priorities with key stakeholders in the areas of primary care, hospital care, consumer representation, research, and government. The survey was used to gather existing virtual care initiatives for older adults and any associated challenges. Co-production processes consisted of individual ratings of initiatives and group-based discussions to identify priority virtual care initiatives and challenges to be addressed for future scale-up. Stakeholders nominated their top three virtual initiatives following discussions. Results: Telehealth was nominated as the highest priority initiative type for scaling up, with virtual emergency department models of care nominated as the highest priority within this category. Remote monitoring was voted as a top priority for further investigations. The top virtual care challenge was data sharing across services and settings, and the user-friendliness of virtual care platforms was nominated as the top priority for further investigation. Conclusions: Stakeholders prioritised public health virtual care initiatives that are easy to adopt and address needs that are perceived to be more immediate (acute more so than chronic care). Virtual care initiatives that incorporate more technology and integrated elements are valued, but more information is needed to inform their potential scale-up. © 2023 by the authors.
- Sinclair, Julia, Aslan, Betul, Agabio, Roberta, Anilkumar, Amith, Brosnan, Mark, Day, Ed, Dowling, Nicki, Flood, Chelsey, Grant, Jon, Halliday, Robyn, Hofvander, Björn, Howes, Leesa, Moseley, Rachel, Myers, Bronwyn, O'Connor, Vincent, Shaya, Gabriel, Thomas, Shane, Robinson, Janine, Chamberlain, Samuel
- Authors: Sinclair, Julia , Aslan, Betul , Agabio, Roberta , Anilkumar, Amith , Brosnan, Mark , Day, Ed , Dowling, Nicki , Flood, Chelsey , Grant, Jon , Halliday, Robyn , Hofvander, Björn , Howes, Leesa , Moseley, Rachel , Myers, Bronwyn , O'Connor, Vincent , Shaya, Gabriel , Thomas, Shane , Robinson, Janine , Chamberlain, Samuel
- Date: 2023
- Type: Text , Journal article
- Relation: Comprehensive Psychiatry Vol. 124, no. (2023), p. 152393-152393
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- Description: Autistic people are more likely to report problematic alcohol and other substance use when compared to the general population. Evidence suggests that up to one in three autistic adults may have an alcohol or other substance use disorder (AUD/SUD), although the evidence base for behavioural addictions is less clear. Autistic people may use substances or engage in potentially addictive behaviours as a means of coping with social anxiety, challenging life problems, or camouflaging in social contexts. Despite the prevalence and detrimental effects of AUD, SUD and behavioural addictions in community samples, literature focusing on the intersection between autism and these conditions is scarce, hindering health policy, research, and clinical practice. We aimed to identify the top 10 priorities to build the evidence for research, policy, and clinical practice at this intersection. A priority-setting partnership was used to address this aim, comprising an international steering committee and stakeholders from various backgrounds, including people with declared lived experience of autism and/or addiction. First, an online survey was used to identify what people considered key questions about Substance use, alcohol use, or behavioural addictions in autistic people (SABA-A). These initial questions were reviewed and amended by stakeholders, and then classified and refined to form the final list of top priorities via an online consensus process. The top ten priorities were identified: three research, three policy, and four practice questions. Future research suggestions are discussed. •Little is known about the overlap between autism and addiction, yet both are common.•This priority-setting partnership identified the top research, policy and clinical practice questions regarding this overlap•Identification of these priorities will assist researchers and experts, and policy makers to address key knowledge gaps.